Dmen004012.1
Basic Information
- Insect
- Diaphora mendica
- Gene Symbol
- -
- Assembly
- GCA_949125395.1
- Location
- OX421311.1:1273230-1277803[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 1.9e-06 0.00025 22.7 0.4 1 21 108 128 108 129 0.94 2 18 1.1 1.5e+02 4.6 0.2 3 23 135 155 134 155 0.92 3 18 0.003 0.4 12.6 0.4 3 23 162 183 161 183 0.96 4 18 0.0019 0.26 13.2 2.2 1 23 188 210 188 210 0.95 5 18 0.00029 0.039 15.8 0.2 1 23 246 269 246 269 0.94 6 18 4.6e-05 0.0062 18.3 1.7 1 23 275 297 275 297 0.98 7 18 7.7 1e+03 1.9 0.3 6 23 308 325 306 325 0.93 8 18 4.1 5.6e+02 2.8 1.0 1 23 331 354 331 354 0.90 9 18 0.0041 0.55 12.2 1.2 2 22 480 500 479 503 0.88 10 18 0.04 5.4 9.1 0.1 3 23 507 528 506 528 0.95 11 18 0.0015 0.2 13.6 0.5 1 23 533 556 533 556 0.95 12 18 6.3e-05 0.0085 17.9 0.4 2 23 562 583 561 583 0.96 13 18 1 1.3e+02 4.7 1.2 2 20 587 605 587 607 0.91 14 18 3.4e-06 0.00046 21.9 1.0 1 23 633 656 633 656 0.95 15 18 0.00031 0.042 15.7 0.5 1 23 662 684 662 684 0.95 16 18 0.065 8.7 8.4 0.1 1 23 690 712 690 712 0.97 17 18 0.0037 0.5 12.4 0.3 1 23 718 741 718 741 0.94 18 18 3e-05 0.004 18.9 0.8 2 23 748 770 747 770 0.95
Sequence Information
- Coding Sequence
- ATGGAGATGGATGCTGCTCTTCCCCCTGGGACGTGCAGCTCCTGTTTCGAAGCTACAATAGCGGCTATGACCTTCAGAAACCTTTGCACGCAGTCGGCGCATCACTGGATCGAGGCTCCTACCTATTTATCCCAAATCCACCCGCCGACGAACGAGGATAAGGCTTACTTCATATTTTATAACGACgaaaaaactataattaaagACCAAGTAGACAATGTGCCAACAAAGGAAGCCGCCTTGGAAAGGTTAAATTTGAGGTATCAGGACAAACCGGAGAAGGTCCGCCGGCCGAAGCGAGCTTATGATCCACTGTCTACTTGCAAATGCCCGGATTGTGGAAAGGTGTTCTCAGTTCCAGATTATTTAAACTCTCATTTAAGAAACACTCTCAAACGAGCTTGCACTAAATGTGGGGTAGTTATATCGAAGAAAAAGATGGCCAAACACATGGCTATACAACACGATATTATAATGGCCGATTGTACTATTTGTTACAAGTTGTTTGAAAACGAAACAGACCTGAAAGATCACTTGAGAGAATCCCACGCAGATAATATACATTGCTGTAGTGTCTGTGGCAATGGTTTCACTAACGAGAGAGCCTTGAGAGCCCATTTATATTCTCATTCGCTGTTTCATTGCAACTCTTGTAGCCTAAGCttcgaaaatataaaatgtcACAAATATCACCAAAAACAATGTTCAAGTGCTAAGCACTCGAGTTTTAAACACTTCATATGCGATTTGTGTGGTGTTACATATAACCGGAAGCCTTCGTTACGAATTCATATCATCCAGAAACATTTGAATGTTCTCCCATATGTTTGTCAGACGTGTGGTAAGAGGACATCTACGCTAGCACATTTGAGATCGCACGAAAAAGTCCATAAGACTGAACGAAagatatttcaatgtttttgtGGAGCGAAATTGCGAACTGAGCTCGGATATCAGCTCCATCAGAGAATACATACCGGTGAACGACCTTACGAATGTGAATTCTGTGGTGATCGATTTTTGTCTTCGTCTAGAAGATTGGATCATATAAAAAGACGTCACAGAGGTTTCAAACAAATGCCACACGCTTGTGATCAATGCTCCGCACGTTTCATGAAAGAAGAATCGTTAATACCTGTCGGCGCGTGTGTAGCTTGCGCCAGCACGGCTCTCGCCGCTCAAGAGTTCCGTCTATTCGTGAGAAATTCACAAAAAACATGGTGGAAAGCTATCCAAAATCTCGCCATTATTCCATACACCACTGCGTCTCCTGTCAAATCAGTTTGTGCCTTCGTAAAACCAAGTGATCTCACGATACAGACTTTCAAAGATTACACACAAGGTGATGCTCGATCCATCCTGAATAGATTAAAAAATCGTGTTACCAAAAAACCTGTTGAAAGAAAGCCTAGAGGGGCACGGTCCGGCCCTTCTTGTAACTGTCCCGATTGTGGCAAATCGTTTTTAAGCCCTTACTTCCTAAGCATGCATTTGAAAAACAGTGGACATAAGGAAGCTTGTCAAATATGCGGTTCTGTCTTCATCagaggcaaagaaatgaaagaTCATCTGTCCTCTGTACACAAAGAAaacgtatttttatgtaaacaatGTCCAATTTTATTCACAAATGAGATACAGCTTAAAAAGCACGTCAAAAAAGCTCATAAAGCAGGAGCACTAACTTGTTCAGATTGTGGAAGAACCTTCCCAAGGCTGGCTTCTTTTGAAAGTCACTCACAGATGCACGCAGTCAGGACTTGCAGAGCCTGCGGTGTTCAGTTTACTAATCGGGGATGCTACAGAGAGCACAGGTCTCAATGTGAGCCTGACGCTAAGCCTAACGCACAAAGCTTCCCTAGAAACCGCCGCTCAAACATTCGAGACCCAGCACAGTTCACTTGTGACCACTGCGGCAAAACATACAATTCCAGACCACAACTCAAGAACCACATAATTTGGATTCATATGAATATACGACCTCATCAGTGTCAATGGTGTGGAAAAAGGTTTTATACTCCCGCCCGTTTGGCTGAACATACTGTTGTCCATACTCGAGTTCGAAATTTCGAATGCGATATCTGTGGCGTGAAGCTCGTATCCAAGATGGCCGCTGTTTACCATAGACGGAGGCACACAGGCGAAAGGCCTTATGAGTGTGAGGATTGTGGTGAGAAATTCATATCTGCGTCGCGGAGATCGGAGCACGCTAAACGTAGACATAataaaggctataggctaccaTGTTTGAAATGTCCTGCTAGTTTTGTTAGGAAACATGAACTGAAAAAGCATATGGAAAAAGCACATAGAGCGCCAGATGCTATATTGACATGGTGA
- Protein Sequence
- MEMDAALPPGTCSSCFEATIAAMTFRNLCTQSAHHWIEAPTYLSQIHPPTNEDKAYFIFYNDEKTIIKDQVDNVPTKEAALERLNLRYQDKPEKVRRPKRAYDPLSTCKCPDCGKVFSVPDYLNSHLRNTLKRACTKCGVVISKKKMAKHMAIQHDIIMADCTICYKLFENETDLKDHLRESHADNIHCCSVCGNGFTNERALRAHLYSHSLFHCNSCSLSFENIKCHKYHQKQCSSAKHSSFKHFICDLCGVTYNRKPSLRIHIIQKHLNVLPYVCQTCGKRTSTLAHLRSHEKVHKTERKIFQCFCGAKLRTELGYQLHQRIHTGERPYECEFCGDRFLSSSRRLDHIKRRHRGFKQMPHACDQCSARFMKEESLIPVGACVACASTALAAQEFRLFVRNSQKTWWKAIQNLAIIPYTTASPVKSVCAFVKPSDLTIQTFKDYTQGDARSILNRLKNRVTKKPVERKPRGARSGPSCNCPDCGKSFLSPYFLSMHLKNSGHKEACQICGSVFIRGKEMKDHLSSVHKENVFLCKQCPILFTNEIQLKKHVKKAHKAGALTCSDCGRTFPRLASFESHSQMHAVRTCRACGVQFTNRGCYREHRSQCEPDAKPNAQSFPRNRRSNIRDPAQFTCDHCGKTYNSRPQLKNHIIWIHMNIRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICGVKLVSKMAAVYHRRRHTGERPYECEDCGEKFISASRRSEHAKRRHNKGYRLPCLKCPASFVRKHELKKHMEKAHRAPDAILTW
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01492234;
- 90% Identity
- iTF_00707196;
- 80% Identity
- -