Dmen005177.1
Basic Information
- Insect
- Diaphora mendica
- Gene Symbol
- -
- Assembly
- GCA_949125395.1
- Location
- OX421311.1:10911331-10913793[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.0013 0.18 13.8 0.5 1 23 5 27 5 27 0.93 2 18 0.095 13 7.9 0.5 1 23 100 122 100 122 0.98 3 18 0.00095 0.13 14.2 0.2 1 23 126 148 126 148 0.95 4 18 0.0077 1 11.4 0.5 1 23 153 176 153 176 0.93 5 18 0.00067 0.09 14.7 2.5 1 23 182 205 182 205 0.96 6 18 3.5e-05 0.0047 18.7 0.2 1 23 212 235 212 235 0.98 7 18 3e-05 0.004 18.9 1.3 1 23 241 263 241 263 0.96 8 18 1.7e-06 0.00023 22.8 2.7 1 23 269 291 269 291 0.99 9 18 0.00068 0.091 14.7 5.2 1 23 297 320 297 320 0.96 10 18 0.054 7.3 8.7 1.6 1 23 432 455 432 455 0.97 11 18 1 1.4e+02 4.6 0.6 2 23 480 502 479 502 0.93 12 18 0.16 22 7.2 0.1 1 23 526 548 526 548 0.96 13 18 0.00029 0.039 15.8 0.2 1 23 552 574 552 574 0.98 14 18 0.0002 0.027 16.3 0.4 1 23 579 602 579 602 0.96 15 18 0.0031 0.42 12.6 0.3 2 23 609 631 609 631 0.93 16 18 0.01 1.3 11.0 5.5 1 23 638 661 638 661 0.97 17 18 2.6e-05 0.0035 19.1 2.7 2 23 668 689 667 689 0.96 18 18 0.00013 0.018 16.9 1.6 1 23 695 717 695 717 0.98
Sequence Information
- Coding Sequence
- ATGAAGAATTTATATATTTGCTTTTACTGTGATCAACAATTCTCAGATCCTGTTAAGCTCAGGCTCCATAACTTAGAACATTCCTTATTGaaaggctatcaaataaaacaGGCGATGTCGAAACTGAGGAAATACGAGTTAGTGAAGATAGATGTGACTGATGTCAGCTGCAAGCTGTGTGAAGATCAAATTCTTGATTTCCCATCTTTGAAATGGCATTTACTTGAAAAGCATTACAAGCAGTTGGACCCCAAATCCGCCGATGGATTGTTGCCATTCAAAGTTACTTCAGACGACTTCCAATGCGTGTTATGTATAGAAAAATACTCGGAGTTTAAATTGTTAAACCAACATATGAATgtacattttcaaaattttatatgCGAGCAATGCGGTACTGGGTTTGTCACACCCGAACGGTTAAGAACTCACGCATTCTCACATGAGACGGGTTCGTTTCCTTGTGATAGCTGCGATAAGGTATTCCGTTCTACTTACGCGAAGAATGAACATTTTGCAACAGTACACATGAAAGTAAAACGTCACAGATGCCCTCAATGTCCTGAAACTTTTAGAAACTATTTCCAAAGAAATAAACACATTTCTTCAGTTCATGGTGTGAAgttaaaagaatttaaatgtaCCATGTGCCCGAAAGTGTTCACATTGAGTGGAAAACTGGGTGTTCATGTCAGGACAGTACACCTGAAGGTTAAGCGACATGCCTGCAAAGTCTGCGAGTGGCAATTTTATTCCAAGTCTGAGTTGAAAGAGCATATGATAAGACACGGTGGTGAAAGAAAATTTCAGTGCAGCGTGTGCAAGAAAGCGTATGCCAGGAAGCATACATTACGAGAGCATATGAGAATACATGAAAATGATAGACGTTTCATATGTGTTACTTGCGGCACTTCGTTTGTACAAAAATGTAGCCTAAAACATCATACTAAAATGCAGCATTCTAACTCAGGGCAAAGATCCGTCTCGCCCATACGTGACTCCAAGCGAAGAATCGTGCCGTTATTCCAGGTGTCTTACGACAGAAGCTTGTGTAAACCATTGGGCACTTTAGTGAACTTCAGTGCACTCAAAAAGACTATTACTAGACATAATACTCCATTGCGAAGTCCTTCTCCTGTAAATATATCACGATCACCATCCCCGTACTTTGAGAGACCAAAATCAATTGAAACTATCAATCCAAAGACTAAGAAAAATCCGGACATAAGACAGAACGCTCTAGCTGTGTTTGAATATTCAACGGTATATCCGTTTGTGTACGGAAATAACAAATTCAAATGTTTTGTTTGCTCGCAACCCTATTTAGATTTACACTTGCTCAAAGAACATATGCGTGAAACTCATAATTTTGCTCCGCTTAAGAGATTAGTTAATAATCGGAGGGAAAACGTTTTAAAAGTGGATGTCAGTGATATTACCTGTAAAATATGTTCGGTAAAACCATCCGACTTGGTAAAGTTAAAACACCATCTCAAAGAAGTTCACGACAAACCAATAAACTTAGATCTTCAAGACAATTTAATACCGTTCAAATTGGAATTAGACAATGGGTCTTATAAGTGTGTCATTTGCCAGGAAATTTTCATCAAAGTAAGAATATTAGTTATTCATATGAGTATACACTTTAATAACTATAGTTGCGAAGTTTGTGGTTCTGCATTCATGACGTTGCGACTTCTAAAGAAACATTTAGAAGTCCACGAAGCCGGTAACTATCCGTGTGACCGTTGTAGCAAAGTTTTTAGCACTCCTTACAAAAGGACGTTGCATATCCGAGGCGTACATCTTAAGCAGTTGCCAAGAAGATGTCCAATTTGTCCAGAGAGGTTTAACTCTAATTATAAAAGGACAATTCATTTGCAAGATGTCCACAATCAGTCAACGAGAGTGCATAAATGTGAAACTTGTGGTCGTGGTTTTAATTTGAAATACCATTTGATATGTCATATTAGGTCTGTTCATTTACAAGAGAGGAATCAACAATGTGAGGTTTGTCAGCAAAGGTTTTGTAATAAAGAGTCTTTGAAGCGTCACATGGTAATACATACTGGCGAAAAAAATCATAAGTGTGAAGTTTGCGGGATGGCATTTTTGAGGAGGAAAAACTTGAAGGATCATTTACGATTGCATAATATAGATTAA
- Protein Sequence
- MKNLYICFYCDQQFSDPVKLRLHNLEHSLLKGYQIKQAMSKLRKYELVKIDVTDVSCKLCEDQILDFPSLKWHLLEKHYKQLDPKSADGLLPFKVTSDDFQCVLCIEKYSEFKLLNQHMNVHFQNFICEQCGTGFVTPERLRTHAFSHETGSFPCDSCDKVFRSTYAKNEHFATVHMKVKRHRCPQCPETFRNYFQRNKHISSVHGVKLKEFKCTMCPKVFTLSGKLGVHVRTVHLKVKRHACKVCEWQFYSKSELKEHMIRHGGERKFQCSVCKKAYARKHTLREHMRIHENDRRFICVTCGTSFVQKCSLKHHTKMQHSNSGQRSVSPIRDSKRRIVPLFQVSYDRSLCKPLGTLVNFSALKKTITRHNTPLRSPSPVNISRSPSPYFERPKSIETINPKTKKNPDIRQNALAVFEYSTVYPFVYGNNKFKCFVCSQPYLDLHLLKEHMRETHNFAPLKRLVNNRRENVLKVDVSDITCKICSVKPSDLVKLKHHLKEVHDKPINLDLQDNLIPFKLELDNGSYKCVICQEIFIKVRILVIHMSIHFNNYSCEVCGSAFMTLRLLKKHLEVHEAGNYPCDRCSKVFSTPYKRTLHIRGVHLKQLPRRCPICPERFNSNYKRTIHLQDVHNQSTRVHKCETCGRGFNLKYHLICHIRSVHLQERNQQCEVCQQRFCNKESLKRHMVIHTGEKNHKCEVCGMAFLRRKNLKDHLRLHNID
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00823274;
- 90% Identity
- iTF_01198012;
- 80% Identity
- -