Basic Information

Insect: Diaphora mendica
Gene Symbol: ken
Assembly: GCA_949125395.1
Location: OX421312.1:33843338-33853986[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 4.3e-07 5.7e-05 24.7 0.5 1 23 244 266 244 266 0.98

2 14 0.15 21 7.3 2.4 1 23 272 295 272 295 0.96

3 14 1.6e-05 0.0021 19.8 0.8 1 23 301 323 301 323 0.98

4 14 2.6e-06 0.00036 22.3 3.1 1 23 328 350 328 350 0.99

5 14 5.8e-06 0.00078 21.2 3.7 1 23 356 378 356 378 0.99

6 14 9e-07 0.00012 23.7 1.1 1 23 384 407 384 407 0.95

7 14 3.9e-05 0.0052 18.6 2.9 1 23 413 435 413 435 0.97

8 14 1.9e-05 0.0026 19.5 0.8 1 23 441 463 441 463 0.98

9 14 5.4e-05 0.0073 18.1 2.1 1 23 469 491 469 491 0.99

10 14 9.3e-08 1.3e-05 26.8 0.7 1 23 497 519 497 519 0.98

11 14 2.3e-06 0.00031 22.5 3.5 1 23 525 547 525 547 0.98

12 14 0.076 10 8.2 2.9 1 23 553 572 553 572 0.95

13 14 1.2e-06 0.00016 23.4 0.7 1 23 578 600 578 600 0.98

14 14 0.0002 0.027 16.3 3.1 1 23 606 628 606 628 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	4.3e-07	5.7e-05	24.7	0.5	1	23	244	266	244	266	0.98
2	14	0.15	21	7.3	2.4	1	23	272	295	272	295	0.96
3	14	1.6e-05	0.0021	19.8	0.8	1	23	301	323	301	323	0.98
4	14	2.6e-06	0.00036	22.3	3.1	1	23	328	350	328	350	0.99
5	14	5.8e-06	0.00078	21.2	3.7	1	23	356	378	356	378	0.99
6	14	9e-07	0.00012	23.7	1.1	1	23	384	407	384	407	0.95
7	14	3.9e-05	0.0052	18.6	2.9	1	23	413	435	413	435	0.97
8	14	1.9e-05	0.0026	19.5	0.8	1	23	441	463	441	463	0.98
9	14	5.4e-05	0.0073	18.1	2.1	1	23	469	491	469	491	0.99
10	14	9.3e-08	1.3e-05	26.8	0.7	1	23	497	519	497	519	0.98
11	14	2.3e-06	0.00031	22.5	3.5	1	23	525	547	525	547	0.98
12	14	0.076	10	8.2	2.9	1	23	553	572	553	572	0.95
13	14	1.2e-06	0.00016	23.4	0.7	1	23	578	600	578	600	0.98
14	14	0.0002	0.027	16.3	3.1	1	23	606	628	606	628	0.98

Sequence Information

Coding Sequence: ATGGAAGTGGACAGATCGTTGCCATTTCTCGATGTTAAATTAACGGTCCTCTCCACCGACCGTCACTATTACTCCAGAATAGTACGGGAAGCAGTCGAaatcaaaaaaaatagaatttcaACAGAGAAGCTGGGTACCGCTTGTCAACATCTTGGAATCCTGTCATCAGCAAATGCAATCGTCAGCGAATACATGTTACTCGACAAGACTCAACGAACGTCCTTGTGCCGGTGCTGTCATGCCCAAGGGAATTTTAAGAACGGTTGGACGGCTGAAAATATTCAAGATGACTATTGTTTGTGGCTAAAAGATACATTTGATATTATTATCTCACCGGTACCCCAAGACATTGGTGTATCATACAGTATATGTGAAATATGTGAGCCGAGACTCAGAGATGCTGCATTGTTTAAAAGACAAGTGTTGTCTTGTGAGGACAAGTTCAGACAGTATCTTTACAATAACTGTCAATTTAAAGATGTATCGGTTTTGGAGAAAGAAGTTAAAAAGGAATTTGAACAACACGATATCAAAGTTCAACACTTCGACCAGTTCCCGCAAGCCGAGGATGATGACCAGCCTCTGTCTGCATTACGTAGCTCTAAGGTCTTGGAGTATGAACAACCGGAGATTCATGATGAGACTGCTGGAGAAGATGTGGATTGGAGAACACCCGATTTAAGTGATGAAGAGGATCTCAAAGAAAAAAAgccaaaaaaatcaaaaaaatattcctGCGAAATTTGCCAAAAGAAATTCTCTTACAACGGTTCTTTAGAGGTTCACATGAAGGTTCACAGTGGGGAAAAATCTTTCACGTGTCGTCTATGCAACAGTTCCCACACAGACAACAAAGAATTAACCAAACATATAACGATAATGCACATAGTCGACAACCAATATCCCTGTAACCAGTGCGAAAAGATCTTCGAAAAAGCAAGACTGCTAAAGAAACATGTAAAAACACATTACACTGAGAAGTTTAAGTGTACAGAATGTCAAAAAGAATTCCAGAGAAAGAAGGGATTAAAAGAACATATGAAAACGCACACTGGGGAGAGGAAATACACATGTGATATTTGCAATAAATCATTTGGACACAATCAGACGTTGAAATCCCATATGTTCACACACACCGGAGAACGACCTTATGTGTGTGATGTTTGCGGCAGAAGATTCCCCCAAAGAACTCATCTCAAAagacatatatttataatccaCGCTGGAATTAAACCCCACAGTTGTAACGTCTGCAAGAAACAATTCTCCAGCAAAAGCTATCTAGCAATACATGAAAGACAACATACCGGGGAAAGACCATATTCTTGCGAAGTCTGCAAGAAAGATTTCACTGCATACACGACTTTGAAAGTCCATATGCGGGTACACACAGGTTTCAAGCCATACACTTGCAGCTTTTGCGATAGACAATTCGCCCAAATGGCTAGTTTTAAATTACATCAAAGGACACATACGGGCGAAAGACCGTTTTCCTGCAAGATTTGCAAAAAACCTTTCTCGGATAATGGGTATTTGAAGATTCATATGCGAGTGCATTCTGGGGAAAAACCGTTTTCTTGCGAGATTTGCAAGAGATGTTTTAGGGAAACTGGTCAGTTAAAGAGACACATGCGTGTACACACTGGTGTAAAACCGTATACgtgtaaaatttgtaataagcAGATAGGCAATTTGTCGAAACATATGAGAGTGCATTCTGAACAGAGGCCTTACAGTTGCACTGTTTGCAATAAACAGTTTTCAATAAATGGTAATTTGAAATTGCATATGAGGGTACATACTGGCGAAAGACCGTTTAGTTGCGACATTTGTAGCAGCCAGTTCACACAAAGTAGTGGTTTAAAGAGGCATCGGTGTGTTCATGGAGGCAAAAGTGATAGTTGA
Protein Sequence: MEVDRSLPFLDVKLTVLSTDRHYYSRIVREAVEIKKNRISTEKLGTACQHLGILSSANAIVSEYMLLDKTQRTSLCRCCHAQGNFKNGWTAENIQDDYCLWLKDTFDIIISPVPQDIGVSYSICEICEPRLRDAALFKRQVLSCEDKFRQYLYNNCQFKDVSVLEKEVKKEFEQHDIKVQHFDQFPQAEDDDQPLSALRSSKVLEYEQPEIHDETAGEDVDWRTPDLSDEEDLKEKKPKKSKKYSCEICQKKFSYNGSLEVHMKVHSGEKSFTCRLCNSSHTDNKELTKHITIMHIVDNQYPCNQCEKIFEKARLLKKHVKTHYTEKFKCTECQKEFQRKKGLKEHMKTHTGERKYTCDICNKSFGHNQTLKSHMFTHTGERPYVCDVCGRRFPQRTHLKRHIFIIHAGIKPHSCNVCKKQFSSKSYLAIHERQHTGERPYSCEVCKKDFTAYTTLKVHMRVHTGFKPYTCSFCDRQFAQMASFKLHQRTHTGERPFSCKICKKPFSDNGYLKIHMRVHSGEKPFSCEICKRCFRETGQLKRHMRVHTGVKPYTCKICNKQIGNLSKHMRVHSEQRPYSCTVCNKQFSINGNLKLHMRVHTGERPFSCDICSSQFTQSSGLKRHRCVHGGKSDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00823265; iTF_01360902; iTF_00824057;
90% Identity: iTF_01360902;
80% Identity: -