Basic Information

Insect: Diaphora mendica
Gene Symbol: baz-2
Assembly: GCA_949125395.1
Location: OX421310.1:50947828-50975274[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.8e-12 1.7e-08 35.4 0.0 2 75 655 731 654 733 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.8e-12	1.7e-08	35.4	0.0	2	75	655	731	654	733	0.87

Sequence Information

Coding Sequence: ATGGACAAAGACGGCGAGGGCGGCGAGCCGGGGAAGGCGCCGCCCGATGGCCTGCTCGACGCCGCTGGTCTCTTTGGTGCATATTGGGGTCGCGATGGAAGTGCCGGTGGTGGAGGGGGCAGTGCAGCGGCGGCGGCACAAGCGCAAGCGCAGGCGGCACTCTTCGGCTTCGGGGGTGGTCGGTACCCACCGCCCACGACGCTTGGGGTTGCCGCTAACCAAGCTGCGTCGCTTGGATTGCACCCTGCTGCCAGTGCCGCCTGGTGGTCAATGGCATCCCACCTGGCGGCTCAGGACTACTTAGCCCGTCTCCAAGCATCGGGTCTAAACTTCCCACCTTTAGCAGACCCTTATGCTGCGCTGTCAGCGCTGTCGGGGGCTGGATTGAAGCAGCCATCTAAACCTGGAAAACTGTCTTCGTCTAGAAATGAGAGGTCAGGTAGAAGCAGTACATCATCCAGCACATCAGCCAAGGACAAGAGTCCCTCGACCAGCTCCAGTTCTCAAAATATGAGTGAGTGGGGAGCACAATACGGTCTTCCAAAAACGTCATCACCATCGGCAATGCATTCACATTCACAGTCTCTCTCAAGTCTCGCCTCTCTCAACAGCCTGGTGTCTGCTTCTCATCAGAGCAAACCTAGCAAACAGTCTATACCCCAAACCTCAAAAAAGCCATCGTCATCGTCTGGAGTCCCTAACTCGAAGGGTAAGGAGCGAGAGCTGGCGCTGCTGCGAGGAGACCTGATGCTGGCGCAGGCGGCCGCTCACGGCGCCTACCACGCCGCTGTTGCTGCTGCCGCTAAGGGAAAGaatATGTCACCACTGTACCCGTTCGGCATGCCTGGTTCAGACAAGGACCGACATGCTGGTATCGATTCACTCACAGGTCTCCCACACACCATACTGAGTGCTGCTTTAGAAGGAGGTGATCCTTCGTCAGTGCTCGGCGGAGTTCGACTACCTCCGGATACGGAAATAATCAAGTATACGTCATCATTAGCGGGACCCAAGGGTGGGTCAGGCGGCACGACGCGGGGCCGCAAGAAGACCATCTCGCTGGACCCGCCGCACGTGAGCCTGCACCCCGCGGCCGAGCGGCCCGACCGCGCCGACCGCACCGACCGCACCGACCGCAATGACCGCACAGCGCCACTGCCTAGCAAACGACCCAAACTGGACGAGTACGGCAATTCCCGGTCGTCGGTTGAAGTGATCCGCCTCCCAAACAAACCGGACCGGCCCGGAGCCAACTCTTTGTCCGGCACACCACCGCCTAACCTATCTGATTATGCAGGTATATCTCGAGAGCTGTTGCAGACGATAGCCAGCCAGAGCGGCGTGAGCCTGGCCGCGCTGGAGCGACAGCTGGCAGGAACCAGCGCGGCCGCCGGAGATTACAGGACCGCAGATTCAGGTTTAAACCTAAGCACAAAAATGGGCTCCGAGTCCCCCATGGACCTGGGCGTGAAGGTCGGAGCTGATGATGACGCGCCTCTCAACCTCTCGCTGAAGCCTACTCCTTCAAGTTCACAAGCATCCGATGCTTTGTCCCGTTTGACATCTCTGAGCAGTTCACTCAACGCTTCATCAAGTCATGACAGAATATCCCGTCGCAAGCCGGGCGTTCGGCCGCGAAGGGCAGGCCCTGAAGCGGGCGAGTCGCCACGCCCTAAGTCCAGCGGGAGCGAGGATAGTGAATCTGTGGCAGGGTGGGCAGGTCGTGAAGGTAGACCTCGCAACCTGGGCCGGGGAGTGAGCAAGCCCAAGAAGAACACGGTCGCGTCTCTGCTGGCTCAGAGCCGTGCTCTCGGACTCAGACCTGCGCTTGCGCATCAGCTGCTAGCTGAAACTGATTTGGAAAAGCTGAAAGCTCTGTTAGGAGAGACAGCGAGCACCGACTCAGAATGTCCGTCCGACAGTTGCCCGTCCGACTCAGACGCGAGCGACACCAGCCGCCGGACCAACGACGCTCAGTTGAGACTGCCGCTGGCACTAGGCTGGAAACGTGTGACAGTGATCAAGGGCCTCTCCCGGAACTGCAGCATCAAGGGTGACGTCACGTACACACCGCCCGAACCTCATGCCGCCGCCAGTATTCGCTCGATGCAGGAGTTACAAAATTTCTTGGACTCAAACCCATTGCCCCCATTATCAACGGATAACTTTAGCTTCAGTGCTCGCACAGTGCTCGGAGAATACGTTCAGCCCGCATCAGATGTCGGCGAACCACTTATATACAacgaaaatgaaataaataaaaggCTGGAGGAGGCGCGCGCGCTGTCGGGCGGGCGGCCCACCCCCCCCCCGCTGGACCGGCGCATGGAGCTGGCGCGCCTGCAGCAGGCCGCGCGTGACGCCAGGCGGGACCACAGCGCGCGCTCGCGCGACCAGGCACGGCTAGAACGTTCAGAAAAAGCAGAACTCGCCAAGCGCGAGAAAGAAGTACGAAGTCAACAACTGCTAGAGCATATCAACAAGAACCGTACGCAGTTGACCATCGAGCCGTTGCCCACGATTCCCAAAAGTGGGATCGACGAGTGGAAAACACCCGAGATAGTGATGGGACCAGCTACTAAGAGTAACAAGGACCGCATTATGCCTCCTATTAGTCTGTCTCTCATACCAGTTTCGGGTCCAAAAGACAGCCAAAATTCTCCTATAAAGACGATGAAATTCGACCAGTCTGGGTGGAAAGAGGAGATAGAAGAATATAACGCCTTAGATAAAATGAAAGACTTCGCTGAAAAAGCAGCATTTGACATGCCCAAACGAAAAGACAAACAATACGATTTCTCAATAAAATCCGTAAACGTAGACAAAAGaataaaaccaccagaaaaagAGAACAATCTAGAAAAACTAATCGAATCGTATTCTAGAATAACAGAGTTCATAAACGGTTGTGATTGGTCGAATTTGGAAACAGATAGACGGACTGAGGATCCGAAATCTttagaacaaaaatatttagatgCCAAAAACGAGTTTATGTCTGAAAATCTTATGTTGATGCCAAAAGACACTACTAAATCTGTGTTGAAAGAAGTGATTGACCTCAGCGAGGACGATGATAATATTTTAACCGATATTATATCAAAGAAAATAAGCAAAGGGACGTTTAATATTGGGAAAGATGGTGCCCTGTCCATATCCGTGCACCCACTCGGCAAGGAAATGTCACTGGTACGTCAATATCGAGAACTAAAAGAAACTAACTTTCGGGATACTGTTTCACTAACCGCACATACGCTTGGCCTACAAATCTAA
Protein Sequence: MDKDGEGGEPGKAPPDGLLDAAGLFGAYWGRDGSAGGGGGSAAAAAQAQAQAALFGFGGGRYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPPLADPYAALSALSGAGLKQPSKPGKLSSSRNERSGRSSTSSSTSAKDKSPSTSSSSQNMSEWGAQYGLPKTSSPSAMHSHSQSLSSLASLNSLVSASHQSKPSKQSIPQTSKKPSSSSGVPNSKGKERELALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSPLYPFGMPGSDKDRHAGIDSLTGLPHTILSAALEGGDPSSVLGGVRLPPDTEIIKYTSSLAGPKGGSGGTTRGRKKTISLDPPHVSLHPAAERPDRADRTDRTDRNDRTAPLPSKRPKLDEYGNSRSSVEVIRLPNKPDRPGANSLSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGTSAAAGDYRTADSGLNLSTKMGSESPMDLGVKVGADDDAPLNLSLKPTPSSSQASDALSRLTSLSSSLNASSSHDRISRRKPGVRPRRAGPEAGESPRPKSSGSEDSESVAGWAGREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHQLLAETDLEKLKALLGETASTDSECPSDSCPSDSDASDTSRRTNDAQLRLPLALGWKRVTVIKGLSRNCSIKGDVTYTPPEPHAAASIRSMQELQNFLDSNPLPPLSTDNFSFSARTVLGEYVQPASDVGEPLIYNENEINKRLEEARALSGGRPTPPPLDRRMELARLQQAARDARRDHSARSRDQARLERSEKAELAKREKEVRSQQLLEHINKNRTQLTIEPLPTIPKSGIDEWKTPEIVMGPATKSNKDRIMPPISLSLIPVSGPKDSQNSPIKTMKFDQSGWKEEIEEYNALDKMKDFAEKAAFDMPKRKDKQYDFSIKSVNVDKRIKPPEKENNLEKLIESYSRITEFINGCDWSNLETDRRTEDPKSLEQKYLDAKNEFMSENLMLMPKDTTKSVLKEVIDLSEDDDNILTDIISKKISKGTFNIGKDGALSISVHPLGKEMSLVRQYRELKETNFRDTVSLTAHTLGLQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00282418;
90% Identity: iTF_01166719;
80% Identity: -