Basic Information

Insect: Diaphora mendica
Gene Symbol: D
Assembly: GCA_949125395.1
Location: OX421317.1:2483296-2484033[+]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.3e-29 6.7e-26 91.9 2.8 1 69 39 107 39 107 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.3e-29	6.7e-26	91.9	2.8	1	69	39	107	39	107	0.99

Sequence Information

Coding Sequence: ATGTCTACATTAAGTCATCATCCTTACGCGTTCTCAATGCATCATGGTATGCTACCGGAGTATCCGAGCGCACCACAACCATTACCGGCGACCTCACCGCAGTCAGAGGGCCATATCAAGAGACCTATGAATGCATTCATGGTCTGGTCCAGGCTTCAGAGACGTCAAATCGCCAAGGACAATCCGAAAATGCATAACTCTGAAATCTCTAAGAGGCTGGGAGCTGAGTGGAAGTTGCTCTCCGAGATGCAGAAGAGGCCATTTATCGACGAAGCGAAGAGGCTGCGGGCTCTCCACATGAAGGAGCACCCGGACTACAAGTACAGGCCACGGAGGAAGCCCAAACCCCCTACCCAAGGAGCCCCAGGTGCGGGAGCGTTCCCCAGTTTCCCTCTGCCATACTTTGCGGGACCGGCTCCCGGTGTAGGACATTTGGACGCCCTTTCGTACCCAGCAGTGTCACCGTACTTCCCACATCAGTTGGATCACCTACAGTTCTCTAAGTTAATGGCTCCGACGGCGGAGAAACTACCGACGGTGTCGTCATCAGCGGCGGCCGTAGTGTCATCGTTCTATTCGTCATTGTACACGTCACCAGCTGCACCTCCGAAACCTTTCCACTCATCGCTGTTCCATCAGTACGGAGTAGCGCCATCCTCGCCTGTATCACCCGTGACTCCGACGCAGCACAGCCCCCACGACGACCAACTGAGGCGGCCGGTGTCCGTCATATATTGA
Protein Sequence: MSTLSHHPYAFSMHHGMLPEYPSAPQPLPATSPQSEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLSEMQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKPPTQGAPGAGAFPSFPLPYFAGPAPGVGHLDALSYPAVSPYFPHQLDHLQFSKLMAPTAEKLPTVSSSAAAVVSSFYSSLYTSPAAPPKPFHSSLFHQYGVAPSSPVSPVTPTQHSPHDDQLRRPVSVIY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00171742;
90% Identity: iTF_00823882; iTF_01197709; iTF_01360602; iTF_00157190; iTF_00706950; iTF_00823028; iTF_00821818; iTF_00112481; iTF_00114086; iTF_01312208; iTF_01317277; iTF_00858530; iTF_01416769; iTF_01490113; iTF_00235843; iTF_00656131; iTF_00467396; iTF_00236614; iTF_01010343; iTF_01358856; iTF_01281323; iTF_00791182; iTF_00013008; iTF_00658387; iTF_00787638; iTF_00341303; iTF_00448119; iTF_00063576; iTF_00432184; iTF_00035644; iTF_00736604; iTF_00806717; iTF_00408447; iTF_00468159; iTF_01564639; iTF_00772864; iTF_00859456; iTF_00947872; iTF_00113315; iTF_01316336; iTF_00178145; iTF_00072802; iTF_00006267; iTF_01081575; iTF_01245922; iTF_00144556; iTF_00412494; iTF_00407573; iTF_00406738; iTF_00932539; iTF_01386691; iTF_00844334; iTF_01341262; iTF_00275251; iTF_00931392; iTF_01387584; iTF_00007072; iTF_01251721; iTF_00681635; iTF_01334884; iTF_00682414; iTF_00683347; iTF_00075527; iTF_01264600; iTF_01453254; iTF_00150535; iTF_00011971; iTF_01332695; iTF_01152146; iTF_01388455; iTF_00055402; iTF_01385739; iTF_00871276; iTF_00968013; iTF_00111650; iTF_01117199; iTF_01119319; iTF_01118298; iTF_01415827; iTF_00827941; iTF_01173261; iTF_00761664; iTF_01402701; iTF_01451439; iTF_01452306; iTF_01138928; iTF_01438913; iTF_01143810; iTF_01147363; iTF_01140901; iTF_01145253; iTF_01149573; iTF_01143078; iTF_01142375; iTF_01144519; iTF_00795691; iTF_01437970; iTF_01141651; iTF_01146197; iTF_01140182; iTF_00970391; iTF_00166906; iTF_01082426; iTF_00971355; iTF_01148795; iTF_00206977; iTF_00044487; iTF_00649992; iTF_00826953; iTF_00143052; iTF_00390356; iTF_00895926; iTF_00649081; iTF_00825721; iTF_00794593; iTF_00908833; iTF_01507201; iTF_01079045; iTF_01079877; iTF_01508049; iTF_00796498; iTF_01506326; iTF_00288034; iTF_00353058; iTF_00421346; iTF_00842658; iTF_00256900; iTF_00461545; iTF_00420525; iTF_01034574; iTF_00954448; iTF_01181872; iTF_01017715; iTF_00114932; iTF_00960148; iTF_00354069; iTF_01033719; iTF_00824728; iTF_01359736; iTF_00418970; iTF_00958650; iTF_00959386; iTF_00419740; iTF_00405890; iTF_00985090; iTF_00986082; iTF_01124578; iTF_01429922; iTF_00290692; iTF_00820073; iTF_00819151; iTF_01534818; iTF_01532003; iTF_01062788; iTF_01063748; iTF_00301162; iTF_00711850; iTF_01064651; iTF_01533036; iTF_00302094; iTF_00445166; iTF_00685425; iTF_00928690; iTF_00446131; iTF_01061878; iTF_00447131; iTF_01533920; iTF_00382595; iTF_01176163; iTF_00942806; iTF_00428996; iTF_01115684; iTF_00689381; iTF_00785989; iTF_00785191; iTF_01361611; iTF_00783468; iTF_01285527; iTF_01363096; iTF_00784379; iTF_00281318; iTF_00636390; iTF_00637639; iTF_00404910; iTF_01166682; iTF_01206534; iTF_01202447; iTF_01204022; iTF_01487686; iTF_00018151; iTF_00017323; iTF_01491923; iTF_00148455; iTF_00660295; iTF_01090759; iTF_01193575; iTF_01337735; iTF_00323496; iTF_00462376; iTF_00156228; iTF_00342185; iTF_00155284; iTF_00325368; iTF_01134776; iTF_00021308; iTF_01135741; iTF_00801832; iTF_01091915; iTF_01018550; iTF_00896794; iTF_00621214; iTF_00925704; iTF_01204872; iTF_01205683; iTF_01203222; iTF_01217480; iTF_00933740; iTF_01248118; iTF_00934749; iTF_01561992; iTF_00647977; iTF_01155177; iTF_01157775; iTF_01156436; iTF_00790250; iTF_01125450; iTF_01331562; iTF_01437034; iTF_00300203; iTF_00922859; iTF_00025228; iTF_00195148; iTF_00250445; iTF_00428109; iTF_01078189; iTF_00957934; iTF_00680527; iTF_00889199; iTF_01153967; iTF_01158942; iTF_01208175; iTF_00364912; iTF_01133712; iTF_00149382; iTF_01153008; iTF_01464144; iTF_00204337; iTF_00673489; iTF_00205106; iTF_00430642; iTF_00960914; iTF_01333810; iTF_01502962; iTF_00186163; iTF_00185296; iTF_00651731; iTF_00687859; iTF_01083315; iTF_01494291; iTF_00249684; iTF_00180461; iTF_00358548; iTF_00357488; iTF_00409268; iTF_00878836; iTF_01178548; iTF_00744621; iTF_01302324; iTF_00026837; iTF_00288853; iTF_00411445; iTF_00410269; iTF_01280278; iTF_01495030; iTF_01495761; iTF_00666519; iTF_00206054; iTF_01260087; iTF_00356184; iTF_00383640; iTF_00786776; iTF_00077465; iTF_00279097; iTF_01151193; iTF_01425049; iTF_00327066; iTF_00869617; iTF_01221559; iTF_00953498; iTF_01496570; iTF_00034715; iTF_00284524; iTF_00840283; iTF_00876155; iTF_00776706; iTF_00775235; iTF_00776003; iTF_00777988; iTF_00247173; iTF_00723047; iTF_00780235; iTF_00781005; iTF_00874445; iTF_00159822; iTF_00778736; iTF_00781808; iTF_00458034; iTF_00213429; iTF_00777365; iTF_00875291; iTF_00779486; iTF_00212447; iTF_00248064; iTF_00457216; iTF_00782624; iTF_00007996; iTF_00261852; iTF_00771068; iTF_01080700; iTF_01502076; iTF_00709222; iTF_00171742; iTF_00642302; iTF_00926590; iTF_01021214; iTF_01071614; iTF_00695583; iTF_01072479; iTF_01220639; iTF_01282271; iTF_01279239; iTF_01425919; iTF_00032896; iTF_00033789; iTF_00164352; iTF_00403795; iTF_00277344; iTF_01073600; iTF_00450098; iTF_00072144; iTF_00677602; iTF_00001161; iTF_00282381; iTF_00000320; iTF_00640308; iTF_00198104; iTF_01403416; iTF_01501099; iTF_01336831; iTF_00125113; iTF_01209256; iTF_00621984; iTF_01026169; iTF_01340097; iTF_00041762; iTF_00049890; iTF_00622818; iTF_00040803; iTF_00123363; iTF_00345796; iTF_00375204; iTF_00449092; iTF_00809125; iTF_00810053; iTF_01029253; iTF_00036710; iTF_00038759; iTF_00771911; iTF_01030215; iTF_01085223; iTF_00850728; iTF_01030216; iTF_00037802; iTF_00973770; iTF_01076490; iTF_01094026; iTF_00726347; iTF_00172940; iTF_00831212; iTF_01538732; iTF_00758157; iTF_00951821; iTF_00364014; iTF_00851790; iTF_01230574; iTF_01527214; iTF_00274415; iTF_00122384; iTF_00120497; iTF_01027314; iTF_01439922; iTF_01377459; iTF_00745684; iTF_00147445; iTF_00273589; iTF_00121430; iTF_00177110; iTF_00039799; iTF_00667479; iTF_01441079; iTF_01526007; iTF_01028280; iTF_01338745; iTF_00042618; iTF_00374106; iTF_00425370; iTF_01031130; iTF_01094906; iTF_00907035; iTF_00907867; iTF_01246971; iTF_00237564; iTF_00888252; iTF_00924668; iTF_00906141; iTF_01084253; iTF_01093085; iTF_01342205; iTF_00043487; iTF_00071423; iTF_00124256; iTF_01192704; iTF_01503866; iTF_00657181; iTF_00659428; iTF_00656130; iTF_00752058; iTF_00289599; iTF_00715775; iTF_01401279; iTF_01148069; iTF_00027736;
80% Identity: -