Basic Information

Insect: Diadocidia ferruginosa
Gene Symbol: met-2
Assembly: GCA_027564275.1
Location: JANSTW010083070.1:2958-9018[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1e-10 4.7e-07 30.1 0.0 9 71 702 766 698 771 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1e-10	4.7e-07	30.1	0.0	9	71	702	766	698	771	0.87

Sequence Information

Coding Sequence: ATGGAGCCGGAGTCGAATCTTCGGCGTCGTATTAATGCTTTAACTCAGGAAGAGCGTTTAAAAGTTCTTGAAAAAACTGAGTCACTTTACAAACAATGTAGAAAACTTAATTCAGACGATTTTATTTTTAACGATGAAAAACAATTGCAGTCGGATGATAGCATTGAGCGCGAAATTTCCGTTGAACAAATAGTTTCAATTGTAAATGATTATCACAATTGTGGAAAGAGTTTGCCAAAAATCATGGAAGAACAAAAATTGACTAATTTTGAAGTAATTGCAGCGTTGAGTGAATATACTTTTAAGCGTATATTTTTTATGGCCCTTCAGGAATGTAATCTTAATATTGATAAATTTTTAGAACAAGGGACTTTGTCTCGTTCCGTTGATTTTTCTGGTGCTATAAAATATATGTATGCTGAACAAAGTAGTATAATTGAATTGATCAATCTAATGTTACAAAAGCCAAATTTGCTACTTGCCGATGTAATTACACAATTACTGTGCTTGCCTTCTTTATGTTTATTATGGGTTACATTGATTTGGATTGAATTAAAAAATCAAAAAATGGCAAATCTTTTTGATTGTAATTGGGAAAAAATCAAGTACCTTGAATTTACAGACGAAGAATTTGTACGTTTAGACGACGAAATTCAAGTTGTTTTTGATTCATACAAACAACACAGCGCAAATTTAGTGCCAAATGTTTTCCCATCAGATCAATTAAAGACAGATCTACAAGTAGTGCGGGAAGTTGTCGAAGATCGATCAAAAATTATAAATGAAACTCTTAAAAGCCTCAAAGATCTTAATCAAATTATTAATAAACGTCCTTTATTAGAAGTAGAAACAATTTTATCTGATTCCTCTGACTCTGAGGCTGGCCCTACGGAAAAGGATGAAATTTGTGTACTGATGCAAAAAGTAACGGGAAAATGGTTGCAAACTGATTTGACAAATGATATTTTAGCTGATGAAATTCAAATTGAAAAATACAATTTTTATTTTGCCAAAACTACAAATCATCTTAATGAAGATGTATACACGATGCAATTCCTTGCGGCAACAAATGCGGTTCGTAGTGTAAAACATAGTGATATAGCTATGGGAACAGCACCTAGCGTTCGATGTCCAGAAGGTACACGGATTATTGCCTTCTATCAACCTCAAAGAAAAAAAACTACAGATATTCAATCAGGCATGTCTAATGTCAATGGTTTTTGGTTAGCAGGTACCGTAGGTGCTAAACCATTAATGCAAAATCGGTTTGAATATTTGATATTTTTTGACAATGGAATTGATTGCTATATTTCACCGGATAATATTCGTTTATTATTAGAACAACCATTGGAGCCGGTTACAAAGCGATTTGAGCCGAGATTAGCTTACACGTTAGTAAAGGATCCAGTAAAACAAAATTTTATTCGAAATTATTTGCATGTCTTTCCAGATTGGCCATTGATTCGTTTAAAAAAATCGGAGAACACTATGCGAGTTTTAGTTCGACGAGATGGAAAAGAAGAATCGGCATTTGTACTTGATGTTGACAGACAAACTTGTCTCTTGCGTTTTCCTGTACTTAGGATAGGTCCAGCCGGAAAAACTGGTCGTGATTGTGTTGCGCTGAATTGTGCGGAACATGAACACATTGATGAATGTGTTTACCGTGGGGATTCTGGCCGATTTCCGACTTTACAAAGCAGTGTTGCGCCAACAAATACTTCAATACGTCGTCTAGGGCGTAACCGTTCACGCTTTGAAATTGCACTTCCTGAATATGATTGCAATTTACAAGATATGAGCAGTTTTAATATAAGTCTTTCGTCTGGATCAACATCGAAATTAAAAACAATGCAAACGGCAAGAAAAAGTAGTAAGAGGCAAGTACTGGAGCTTGAAAATAATGTTAATATTTCTGGATCCAACTCTGACTTAATTACACGACGAAAGTTAAGCAATAAGGTAAAAGAAGATTATTTGAAAGCGCCTGATTGGTGCAGTCGTTTTAAATATTGTTCTCATAACAAATGCACATCTACTTGTATTAAGCAACTCAAAATTGATTTAAAACTGGAAGACTTTGTGCCATGCTCTCCTTACTTTATTCCACTTATTAATGGGTGGACTAGAGAATTACGTCGTGTTAGAACATATGGCGTTAGATGTGAAAATACACGTTCTATGGTAGTCTATCGAGCGCCTTGTGGAATTAGGTTGTTAAAAATCGAAGATATAGCCAAATATTTGCAAGTTACTGCGACCGAGAATTTGACTATTGATCTTTTTTCATTTGATTTGAATATTCGTCCAACAGTTATTATAAGACCTTTCAAAGAAGAAATTATTTTGCAAGATGACTTTGCCAAAGGTTTAGAAGACGTAAAAATTGCAGTTGTAAATGCTGTATCTCAAGATAAAACTCCCTCTATGACATATCGTGCAAGACGTTTTGCTGATTCCTCAATAATTGATGGAAGTGTTCAACCACAATTTTGTTCTGGTTGCAGTTGTTTGGACGACTGTTCTGATCCAAGTAAGTGTGAATGCCAAAAGCTTACAATATCTTCTCACGATCGATTATCGGCTAGTTTACGTGTCAATGGACAAACAACTTATCAATATCGGTCTCTTTCAGACAAAGTAATATCTGGTATTTATGAATGCAATGATATGTGTTCTTGTTCAAAGAAATTATGTTACAATCGTGTGGTTCAACAAAACATAAAAATTCCATTACAACTTTATATGACCGCAGAAACTGGGTGGGGTGTACGAACTCTTGTTGATATTCTTGCTGGTTCTTTTATATGTACATATTCTGGTCGACTATTAACTGATAGAATGGCAGAACTACAGGGACGTGAAGTAAGTGATATGTATTTGGCTGAATTAGATTTACATGAAGTTGTGGAGGCAGAAAAGCAACAGCAAGGCATTGATTTAATAGATGACGATGAAGGAATTGCTTCTGGAGACGAAAATTATTTTCCTTCGTCTGAGACAAATGAAAATCAACAGGAACAAAAAGCTGTCAGGAAAGAATCACTTATCCCTCTTATTGATGAAGAAATTGCGGCACTTGAAGAAAGTGATGTAGATTCTTTAAGACCAAGTACATCTGCACAAGCTTCTACTTTACATCATAATTCTAAATTATTTAATTTTGAAACATATTTTGGTGATAATTCTCTCTTTATTGTTGATGCACAAGAGTCTGGGAACATTGGTCGATTTTTGAACCATTCATGCGAGCCAAATGTATTTGTACAAATGGTGCTTGTGGATACACATGACTTACGTTTGCCTTGGGTTGCTTTTTTTGCAGAGACTTTTGTTAAAGCCGGAGAGGAACTTCGTTGGAATTATGGTTATTCTCCGAATTCTGTTCCCGGAAAAGTGCTTATTTGTAAATGTGGGAGTCAACATTGTCAAGGTCGGCTACTATAA
Protein Sequence: MEPESNLRRRINALTQEERLKVLEKTESLYKQCRKLNSDDFIFNDEKQLQSDDSIEREISVEQIVSIVNDYHNCGKSLPKIMEEQKLTNFEVIAALSEYTFKRIFFMALQECNLNIDKFLEQGTLSRSVDFSGAIKYMYAEQSSIIELINLMLQKPNLLLADVITQLLCLPSLCLLWVTLIWIELKNQKMANLFDCNWEKIKYLEFTDEEFVRLDDEIQVVFDSYKQHSANLVPNVFPSDQLKTDLQVVREVVEDRSKIINETLKSLKDLNQIINKRPLLEVETILSDSSDSEAGPTEKDEICVLMQKVTGKWLQTDLTNDILADEIQIEKYNFYFAKTTNHLNEDVYTMQFLAATNAVRSVKHSDIAMGTAPSVRCPEGTRIIAFYQPQRKKTTDIQSGMSNVNGFWLAGTVGAKPLMQNRFEYLIFFDNGIDCYISPDNIRLLLEQPLEPVTKRFEPRLAYTLVKDPVKQNFIRNYLHVFPDWPLIRLKKSENTMRVLVRRDGKEESAFVLDVDRQTCLLRFPVLRIGPAGKTGRDCVALNCAEHEHIDECVYRGDSGRFPTLQSSVAPTNTSIRRLGRNRSRFEIALPEYDCNLQDMSSFNISLSSGSTSKLKTMQTARKSSKRQVLELENNVNISGSNSDLITRRKLSNKVKEDYLKAPDWCSRFKYCSHNKCTSTCIKQLKIDLKLEDFVPCSPYFIPLINGWTRELRRVRTYGVRCENTRSMVVYRAPCGIRLLKIEDIAKYLQVTATENLTIDLFSFDLNIRPTVIIRPFKEEIILQDDFAKGLEDVKIAVVNAVSQDKTPSMTYRARRFADSSIIDGSVQPQFCSGCSCLDDCSDPSKCECQKLTISSHDRLSASLRVNGQTTYQYRSLSDKVISGIYECNDMCSCSKKLCYNRVVQQNIKIPLQLYMTAETGWGVRTLVDILAGSFICTYSGRLLTDRMAELQGREVSDMYLAELDLHEVVEAEKQQQGIDLIDDDEGIASGDENYFPSSETNENQQEQKAVRKESLIPLIDEEIAALEESDVDSLRPSTSAQASTLHHNSKLFNFETYFGDNSLFIVDAQESGNIGRFLNHSCEPNVFVQMVLVDTHDLRLPWVAFFAETFVKAGEELRWNYGYSPNSVPGKVLICKCGSQHCQGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -