Basic Information

Gene Symbol
Rfx2
Assembly
GCA_027564275.1
Location
JANSTW010043203.1:2553-5441[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.2 1.2e+04 -2.3 0.0 27 40 19 31 2 39 0.56
2 2 2e-28 2.2e-24 86.7 0.0 4 65 109 170 107 173 0.97

Sequence Information

Coding Sequence
ATGTGGGTTAATGAATTTATTAATCCTCAACGTCGCACCTGTTCAGAATTATCAAAGCATTATCAGTCTATACAATCGATACAAACACCACCGTTACAATCAACTTCAATTTCGTCGCAACAAACAACAGTACAAAATAATTGTACCACAAACGGCTCTTCCGCAAATAATGATACAAATACTGGAGATACATATGTTTTACACAAATCGCAACAACAGTTATCCCCACCGTCAAATTCACCCACAATTTCGGTGGATGACGACATGCCCAATAATATTTGTGGAAGCAATGGACTTGGCCATACTGCTAGAGCGCCACCAGAAACGCTAGAATGGCTAAGCAATAATTACGAGCCTTGTGAAGGTGCTTCATTACCAAGATGCACTCTCTACGACCATTACATAACTCATTGCAAAGAATCTGGTTTGGAACCTGTAAATGCAGCTTCATTTGGCAAACTTATTCGATCTGTCTTCAAAGGTCTTCGTACACGTCGACTTGGGACAAGAGTAGGCGTATTTCTGGTGCTTTTCAACAAGTTGGAATTGGTGCTACAATGCATCGGAGCTTAA
Protein Sequence
MWVNEFINPQRRTCSELSKHYQSIQSIQTPPLQSTSISSQQTTVQNNCTTNGSSANNDTNTGDTYVLHKSQQQLSPPSNSPTISVDDDMPNNICGSNGLGHTARAPPETLEWLSNNYEPCEGASLPRCTLYDHYITHCKESGLEPVNAASFGKLIRSVFKGLRTRRLGTRVGVFLVLFNKLELVLQCIGA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-