Basic Information

Insect: Diabrotica virgifera
Gene Symbol: -
Assembly: GCA_003013835.2
Location: ML018621.1:46560-56351[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 8.7e-07 0.00023 24.1 2.8 1 23 112 134 112 134 0.98

2 21 9.6e-07 0.00025 24.0 1.0 1 23 140 162 140 162 0.98

3 21 8.5e-07 0.00022 24.1 2.0 1 23 169 191 169 191 0.98

4 21 6.9e-07 0.00018 24.4 0.5 1 23 197 219 197 219 0.98

5 21 1.6e-05 0.0041 20.2 3.7 1 23 225 247 225 247 0.98

6 21 5.8e-05 0.015 18.4 3.4 1 23 253 275 253 275 0.98

7 21 7.1e-06 0.0018 21.2 0.6 3 23 283 303 281 303 0.98

8 21 4.9e-07 0.00013 24.9 2.5 1 23 309 331 309 331 0.98

9 21 6.5e-07 0.00017 24.5 1.3 1 23 337 359 337 359 0.98

10 21 9.1e-08 2.4e-05 27.2 1.0 1 23 365 387 365 387 0.99

11 21 1.2e-06 0.00031 23.7 1.7 1 23 393 415 393 415 0.98

12 21 2.4e-07 6.1e-05 25.9 1.3 1 23 421 443 421 443 0.98

13 21 4.3e-07 0.00011 25.1 1.8 1 23 449 471 449 471 0.98

14 21 2.2e-07 5.8e-05 26.0 2.9 1 23 477 499 477 499 0.98

15 21 9.6e-07 0.00025 24.0 2.7 1 23 505 527 505 527 0.98

16 21 0.00025 0.065 16.4 4.2 1 23 533 555 533 555 0.98

17 21 4.8e-06 0.0012 21.8 0.7 3 23 563 583 561 583 0.98

18 21 1.3e-06 0.00034 23.6 2.8 1 23 589 611 589 611 0.98

19 21 8.8e-06 0.0023 21.0 0.8 1 23 617 639 617 639 0.99

20 21 1.1e-06 0.00029 23.8 1.4 2 23 646 667 645 667 0.98

21 21 1.4e-06 0.00037 23.5 2.1 1 23 673 695 673 695 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	8.7e-07	0.00023	24.1	2.8	1	23	112	134	112	134	0.98
2	21	9.6e-07	0.00025	24.0	1.0	1	23	140	162	140	162	0.98
3	21	8.5e-07	0.00022	24.1	2.0	1	23	169	191	169	191	0.98
4	21	6.9e-07	0.00018	24.4	0.5	1	23	197	219	197	219	0.98
5	21	1.6e-05	0.0041	20.2	3.7	1	23	225	247	225	247	0.98
6	21	5.8e-05	0.015	18.4	3.4	1	23	253	275	253	275	0.98
7	21	7.1e-06	0.0018	21.2	0.6	3	23	283	303	281	303	0.98
8	21	4.9e-07	0.00013	24.9	2.5	1	23	309	331	309	331	0.98
9	21	6.5e-07	0.00017	24.5	1.3	1	23	337	359	337	359	0.98
10	21	9.1e-08	2.4e-05	27.2	1.0	1	23	365	387	365	387	0.99
11	21	1.2e-06	0.00031	23.7	1.7	1	23	393	415	393	415	0.98
12	21	2.4e-07	6.1e-05	25.9	1.3	1	23	421	443	421	443	0.98
13	21	4.3e-07	0.00011	25.1	1.8	1	23	449	471	449	471	0.98
14	21	2.2e-07	5.8e-05	26.0	2.9	1	23	477	499	477	499	0.98
15	21	9.6e-07	0.00025	24.0	2.7	1	23	505	527	505	527	0.98
16	21	0.00025	0.065	16.4	4.2	1	23	533	555	533	555	0.98
17	21	4.8e-06	0.0012	21.8	0.7	3	23	563	583	561	583	0.98
18	21	1.3e-06	0.00034	23.6	2.8	1	23	589	611	589	611	0.98
19	21	8.8e-06	0.0023	21.0	0.8	1	23	617	639	617	639	0.99
20	21	1.1e-06	0.00029	23.8	1.4	2	23	646	667	645	667	0.98
21	21	1.4e-06	0.00037	23.5	2.1	1	23	673	695	673	695	0.98

Sequence Information

Coding Sequence: ATGGGTCAACACCCGCAAAAACTGTTGTACAAGTTTACAGCAGAAGAATTAGAAAACTTTACCCTACAATACTTTAGAAAATATGTGCATCCGTGGGAATTACTTCAATCTTGGTCTAAATTACCCAAGAAAGCAGTTCAAGATTTTGAGGATCAGACTCGTCTTCCATATTATGTACATTTTAATCGTCCCGAGTGGAGAACAGAGCTCGAAGGTGTCATATATGAAGATACAGCAACTGATGAATGCAACGAATTAAAAGATCACGTTATAAGTAAGCAATTGACCCAATGTACAACTACCGTAAAGAAAGAAAACGCTGTAGAAAAACCTTTTGAATGTGAAatatgcaccaaacagttttcgtACAGATCTCACTTGAAAATTCATATGATAActcatactggtgaaaaacctttttCGTGTGGAGTTTGCACCAAACAATTTACACAAAGTTCAGCTTTAAAACAGCATATGAAAATTCATACCACTGGAAAAAGTAAATTTGAATGTGACatatgcaccaaacagttttcaaacAAGTCTTATTTAAAACTACATATGAAATTGCACACTGGTGAAAATCCTTTTGTGTGTGAAGTTTGCACCAAGCAGTTTACTCAAAGTTCTTCTTTAAAAGTACATATGGCAATGCACACTGGAGAAAGTCAATTTGAATGTGAAGTATGCGCCAAACAGTTTTCTCATAGTTCTCATTTAAAACTTCATATGATAAAGCACTCTACTGAAAAACAGTTTGAATGTGAAatatgcaccaaacagttttcacaCTATTCTTCTTTAAATATGCATAAGAAAATACACACTGGAGATAACCTTTTTGGATGTGAAATTTGTACCAAACAGTTTGCAAGAAGTCAAGATTTAACGAGACATTTGAGAATACACAATGGagaaaaactatttgtatgtaaCATATGCTCAAAACAGTTTTCACAAAGTGCTCACTTAAAGAGTCATATGCTAActcatactggtgaaaaaccttttgAATGTGAAGTTTGCTCCAAACAATTTACACAAAGCTCTTCTTTAAAACAGCATATGATAAGGCACACTGGAGAAGGTCAATTTAAATGTGAGatatgcaccaaacagttttcacgAAGTGCTAACTTAAAAATTCATATGATAActcatactggtgaaaaaccttttaCATGTGAAGTTTGCGCCAAACAGTTTACTCAAAATTCTTCTTTAAAAACACATATGAAAATGCACTGTgaagagagtaaatttgaatgtgaaatatgcaccaaacagttttcacaaAGTGCTCACTTAAAAGCTCATATGATAACTCATACTGATGAAAAACCTTTTGAGTGTGAAGTTTGCACCAAGCAGTTTACACAAAGTTCTTCTTTAAAAAAGCACATGGAAAGGCACACTGGAGAAGGTcaatttgaatgtgaaatttgtagcaAACGGTTTTCACGAAATCATGATTTAACGAGACATTTGAGAATACACAATACagaaaaactatttgtatgtaaCCTGTGCACAAAGCAGTTTTCACAAAGTGATTACTTAAAGACTCATATGAAAACTCATACTGATGAAAAACCTTTTGAGTGTGAAATTTGCTCGAAACAGTTTAAACAAAATTGTTCTTTAAAACTGCATAAGAAAGTACATACTGGTGATAACCTTTTTGGATGTGAAATTTGTACCAAACAGTTTGCAAGAAGTAAAGATTTAACGAGACATTTGAGAATACACAGTGGAGAAAAACTCTTTTCATGTAAAATATGCAACAAACAGTTTTCACAAAGTGCCCACTTAAAGGGTCATATGCTAActcatactggtgaaaaacctttcaaGTGTGAAGTTTGTATCAAAGCGTTTACACAAAGTTCAGCTTTAAAACAGCATATTAAAAGGCACACTGGAGAACTTAAAGTTAAATGTGAAatatgcaccaaacagttttcacaaAGTGCTCACTTAAAAGTTCATATGATAActcatactggtgaaaaaccttttaCATGTGAAGTTTGCGCCAAACAGTTTACTCAAAATTCTTCTTTAAAACAGCATATGAAAAGGCATGCTGGAGATAATTGA
Protein Sequence: MGQHPQKLLYKFTAEELENFTLQYFRKYVHPWELLQSWSKLPKKAVQDFEDQTRLPYYVHFNRPEWRTELEGVIYEDTATDECNELKDHVISKQLTQCTTTVKKENAVEKPFECEICTKQFSYRSHLKIHMITHTGEKPFSCGVCTKQFTQSSALKQHMKIHTTGKSKFECDICTKQFSNKSYLKLHMKLHTGENPFVCEVCTKQFTQSSSLKVHMAMHTGESQFECEVCAKQFSHSSHLKLHMIKHSTEKQFECEICTKQFSHYSSLNMHKKIHTGDNLFGCEICTKQFARSQDLTRHLRIHNGEKLFVCNICSKQFSQSAHLKSHMLTHTGEKPFECEVCSKQFTQSSSLKQHMIRHTGEGQFKCEICTKQFSRSANLKIHMITHTGEKPFTCEVCAKQFTQNSSLKTHMKMHCEESKFECEICTKQFSQSAHLKAHMITHTDEKPFECEVCTKQFTQSSSLKKHMERHTGEGQFECEICSKRFSRNHDLTRHLRIHNTEKLFVCNLCTKQFSQSDYLKTHMKTHTDEKPFECEICSKQFKQNCSLKLHKKVHTGDNLFGCEICTKQFARSKDLTRHLRIHSGEKLFSCKICNKQFSQSAHLKGHMLTHTGEKPFKCEVCIKAFTQSSALKQHIKRHTGELKVKCEICTKQFSQSAHLKVHMITHTGEKPFTCEVCAKQFTQNSSLKQHMKRHAGDN*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00437746;
90% Identity: iTF_00437746;
80% Identity: iTF_00437746;