Basic Information

Insect: Diabrotica virgifera
Gene Symbol: Hr39
Assembly: GCA_003013835.2
Location: ML016195.1:405616-427564[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 5.8e-10 2.4e-05 26.7 0.1 1 107 132 251 132 263 0.66

2 2 1.2e-72 5.2e-68 233.1 0.2 205 408 262 460 242 460 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	5.8e-10	2.4e-05	26.7	0.1	1	107	132	251	132	263	0.66
2	2	1.2e-72	5.2e-68	233.1	0.2	205	408	262	460	242	460	0.96

Sequence Information

Coding Sequence: ATGCCGAACTTTCACAGCAGCCCACTACACCAACACAGTTACATATACAGAAGTTTGCAGGAcgaaaatttacagtattctaCAGAACAAGACACCTTGGATGAGACTGAAGATAAATCTGGTATAATACATGCATCTCTTCCAGCCCAGCCAGGAATATCTAGGCAACAGcTTATCAACAGCCCTTGTCCAATCTGCGGCGACAAAATCTCAGGTTTCCACTACGGCATCTTCAGTTGCGAATCTTGCAAAGGTTTCTTCAAGAGGACTGTCCAAAACAGGAAAAACTACGTGTGTCTAAGAGGCGCTCAATGTCCCGTAACTGTAGCAACGAGGAAAAAATGTCCCGCTTGTCGATTCGAGAAGTGTCTGCAGTGCGGGATGAAACTAGAAGCCATAAGAGAGGATAGAACGAGAGGCGGTAGATCGACGTATCAGTGCAGTTATTCACTGCCCCCTTCACTTGCCAACCATTCCGACTTAAGAGCCAGTTCGACGGATTTGCGACAGATGGGCGAAGGTCATCAGAGTCTGACGGTCAAGCTGGAACCGCCCGATCCTCAGGTGGCTTCTGCAAAGAGGAGTATGTTTCCTGGATCTAAAGGTGTTCCTCCATTATTACAGGAAATAATGGAAGTCGAACACTTATGGCACTACAACGAATCCGAGCTAAACAAGCTGTACACCGATGGCCATCTGGGCAAAGAGGGTTCCAGCGGGGCGGTGAACAATCTCTCCACTCACCCCCTTTTGGCCGGGACGGCACTGGCCGCTTCGGCGGACACGAGTCCTGACTTCGTGGCGAACCTCTGCAATATAGCCGATCATCGGCTCTACAAAATCGTCAAATGGTGCAAGAGTCTTCCGTTGTTCAAGAATATTTCGATTGACGATCAAATATGTCTCCTGATCAACTCCTGGTGCGAATTGCTCCTGTTCTCGTGTTGTTTTCGGTCGATGACAACACCTGGAGAGATCAGGATATCCCTCGGGAAGAGTATATCGTTGGCTCAGTCGCGGGAGATGGGTATGCAGGCATGTATAGAGCGAATGCTCAATTTCACTGAGCAACTGCGAAGATTGCGAGTGGATCAATACGAGTATATCGCTATGAAGGTGATAGTACTACTTACTTCAGATACTTCCGAGTTAAGAGAAGCTGAGAAAGTCAGGTTGTCCCAAGAAAAGGCTCTAAAAGCCTTACAAGATTATACTTTATCTCATTACCCGGAAAGTCCGGCTAAATTTGGCGAACTACTTTTAAGGATTCCCGAATTACAAAGAACATGTCAGGTCGGTAAAGAATTATTGACGATAAAATCAAAAGACGGAGATGGACCCAGTTTCAACCTCCTGATGGAGCTCCTTAGGGGGGACCACTGA
Protein Sequence: MPNFHSSPLHQHSYIYRSLQDENLQYSTEQDTLDETEDKSGIIHASLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAQCPVTVATRKKCPACRFEKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLANHSDLRASSTDLRQMGEGHQSLTVKLEPPDPQVASAKRSMFPGSKGVPPLLQEIMEVEHLWHYNESELNKLYTDGHLGKEGSSGAVNNLSTHPLLAGTALAASADTSPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMTTPGEIRISLGKSISLAQSREMGMQACIERMLNFTEQLRRLRVDQYEYIAMKVIVLLTSDTSELREAEKVRLSQEKALKALQDYTLSHYPESPAKFGELLLRIPELQRTCQVGKELLTIKSKDGDGPSFNLLMELLRGDH*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01296227;
90% Identity: iTF_01047319;
80% Identity: iTF_00436996;