Basic Information

Insect: Dermolepida albohirtum
Gene Symbol: topi
Assembly: GCA_031893035.1
Location: JAVIWB010002114.1:146982-161313[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00058 0.11 14.1 1.3 3 21 127 145 125 146 0.93

2 14 3.9e-07 7e-05 24.1 0.9 1 23 171 193 171 193 0.97

3 14 0.015 2.7 9.7 2.0 2 23 200 221 200 221 0.95

4 14 0.28 50 5.7 0.0 2 19 240 257 239 260 0.91

5 14 4.8e-05 0.0087 17.5 0.8 2 23 327 348 326 348 0.97

6 14 6.3 1.2e+03 1.4 0.1 1 21 354 374 354 375 0.84

7 14 0.13 24 6.7 3.3 2 20 391 409 390 414 0.82

8 14 0.0015 0.27 12.8 0.1 1 23 541 564 541 564 0.94

9 14 0.002 0.36 12.4 0.2 1 23 568 590 568 590 0.97

10 14 8.5e-06 0.0016 19.9 5.4 1 23 596 618 596 618 0.98

11 14 0.017 3.1 9.5 0.2 1 23 624 649 624 649 0.96

12 14 0.086 16 7.3 2.9 1 23 655 677 655 677 0.86

13 14 1.1e-05 0.0021 19.5 0.5 3 23 685 705 683 705 0.98

14 14 2.8e-06 0.00051 21.4 0.7 1 23 711 734 711 734 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00058	0.11	14.1	1.3	3	21	127	145	125	146	0.93
2	14	3.9e-07	7e-05	24.1	0.9	1	23	171	193	171	193	0.97
3	14	0.015	2.7	9.7	2.0	2	23	200	221	200	221	0.95
4	14	0.28	50	5.7	0.0	2	19	240	257	239	260	0.91
5	14	4.8e-05	0.0087	17.5	0.8	2	23	327	348	326	348	0.97
6	14	6.3	1.2e+03	1.4	0.1	1	21	354	374	354	375	0.84
7	14	0.13	24	6.7	3.3	2	20	391	409	390	414	0.82
8	14	0.0015	0.27	12.8	0.1	1	23	541	564	541	564	0.94
9	14	0.002	0.36	12.4	0.2	1	23	568	590	568	590	0.97
10	14	8.5e-06	0.0016	19.9	5.4	1	23	596	618	596	618	0.98
11	14	0.017	3.1	9.5	0.2	1	23	624	649	624	649	0.96
12	14	0.086	16	7.3	2.9	1	23	655	677	655	677	0.86
13	14	1.1e-05	0.0021	19.5	0.5	3	23	685	705	683	705	0.98
14	14	2.8e-06	0.00051	21.4	0.7	1	23	711	734	711	734	0.98

Sequence Information

Coding Sequence: ATGAATAATGCAGatataagttttataaaagTTCATCAAATAGATCCTGATGGTACTGTAAATTCTTATCAGTATGAAGTTGATAACATGTCCCAAGAATTTATAATGAAGACAAGCTTAGCTCCTTCCTATAATACTAATTTTGATATACCTTTTTCTtcaagtgaaaaatttaattttaaatttcgatttttgaatttggaaaattcttcgATAAGAGTTATAAAAATTGGAGGAGTTGAAGATCTTAATCCTATGAATTATGCTACTGAAATATCTACAGTGCTAAATGATCCTTatgaaaataaatctgttatctGTGGAAATATTCCATCCAAAAGGGAATCAAAAATTCCTAATATACCTACCATGATAATTTGTCAAAATTGTGATACAAATTTTCCCACAAAATATCAGTATCAGAGACATCAATGTGAGTTCaatgctgataaagtggttctTAAGCCAAATGTTGATATAAAAGACATAGATAAAGGTATGAGAATGAAGTTTGACTGCCCAACTTGTGGAAAGCAGTTtgttagtaaaaataatttagaaagacATCAAACAAGTCATGATGAAACTAACATTAATGTATGTGAGCACTGTAGTAAACAATTTGTAAGTGAAAATCGCTTACGTATTCATAAAGAAAACCATTGCAAGAAAGCTGGTGatatatctaaattttatagAAGTGATGTAACTGTTTGGAAATGTCTTGGTTGTTATCAAGTATTTGCAACACCAGCTTCTGCTTCCAAGCATGctgaaaattgttttgaaaattttggtgCTAATGGATCAAAAAATAACAGTATAGATGAAAATGAGTGCAAAATTTCATCTAATGAAACAAAGGATCTTTCGCAAGATTCATCAGATTTAGCTGATCGTGGAATTTCATATAATGGCAAACCGAATGATAATCTTACTCTTAAAAACGTGCAAAAGTTTTTGACTGAGTTGCTTCTTCAATGTGAATATTGTAATCGTACATATGCTGATAAAAATCGGTTATTAGCTCACCAAAAATCACATTCCACAAGGGTAAATTATGAGTGCATTACTTGTAATTTAACATTTGATTCATATGTGTTAGCATCTAAACATTGGTTAACAAAATGTTCTGATGAAGCAAATCTCTtttatttaccaaaattaaCATACTGTGAATATTGTGATAGAACTTTTAAATCTCACGagatattatatacacataaatttaagaaaaaacattATACACCTAAGGTGTTTGCACCAGTAGATTCTAATTCTAACGATACAAACAAAGAACATTTAAAAGACAATACCATGAAAATAGTTGAGAATAAAGAAGCCatagtaaaattaatagaagatgTATTATTTGCAATGAATGTtccaacagaaaataaatataatgataataataataaagagacaataaaaaatactgtGGATGATAGATCgcaagacatttgcattaaatcAGAAATTTTCAGTGAGTCTagtagtttttctaaatcagaCACATCACAAGATTCAGAGAAAAAGAAACGTGGCAGAAAAAGAAAGTCTCCTAGGCAAACAACTAAGACAAAACGTTTAAGCGCCATTGTTGAATCTGGTTACAAATACCAATGTGAAAGGTGTGTTAAAGTTTTCGACAGTGTAGTTGATTTGGAAAACCATAGAGAGTTAGAGCATCctgcaaaatttaaatgtgaagaATGTGGGCAGGTTGTTCACAGTGCAAAGGCATTATTAATACATAGTAGAGCCCATCAAAGCTTAAAACCTTATGTTTGTGAAATTTGCAAAAGATGTTATTCTCAAACATCACATTTATGGCAACATATGAGATTTCATCAAGGTATAAAACCGTTTGCATGTCCCCACGAAGGTTGTGAAGCAAGATACACAATTCGTCCAGATTTAAAGGATCATATAAGAAAAGTGCATACCAGAGAAAGACCTTTTAAATGCTCAGTATgtgataaatgttttttaacagGATCGGTTTATTATCAACACCGCTTAATTCATACAAATGATCGTAGATATGGTTGTgatATTTGCCAAAAGAGATTTTTCCGCGCTGACGCCCTAAATAATCACAGAAGAATCCATACAGATGAACGTCCATATCCCTGCGATATTTGTGGTAGACAATTTAGACAGAAAGGTGACCGTAATAAACACGTCCGAACACAACATCCATCCTGA
Protein Sequence: MNNADISFIKVHQIDPDGTVNSYQYEVDNMSQEFIMKTSLAPSYNTNFDIPFSSSEKFNFKFRFLNLENSSIRVIKIGGVEDLNPMNYATEISTVLNDPYENKSVICGNIPSKRESKIPNIPTMIICQNCDTNFPTKYQYQRHQCEFNADKVVLKPNVDIKDIDKGMRMKFDCPTCGKQFVSKNNLERHQTSHDETNINVCEHCSKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCLGCYQVFATPASASKHAENCFENFGANGSKNNSIDENECKISSNETKDLSQDSSDLADRGISYNGKPNDNLTLKNVQKFLTELLLQCEYCNRTYADKNRLLAHQKSHSTRVNYECITCNLTFDSYVLASKHWLTKCSDEANLFYLPKLTYCEYCDRTFKSHEILYTHKFKKKHYTPKVFAPVDSNSNDTNKEHLKDNTMKIVENKEAIVKLIEDVLFAMNVPTENKYNDNNNKETIKNTVDDRSQDICIKSEIFSESSSFSKSDTSQDSEKKKRGRKRKSPRQTTKTKRLSAIVESGYKYQCERCVKVFDSVVDLENHRELEHPAKFKCEECGQVVHSAKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYGCDICQKRFFRADALNNHRRIHTDERPYPCDICGRQFRQKGDRNKHVRTQHPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00627609;
90% Identity: iTF_00990900;
80% Identity: -