Dtem038354.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dasypolia templi
Gene Symbol
IBTK
Assembly
GCA_963555695.1
Location
OY743154.1:11973527-11980229[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 4.9e-16 3.7e-13 51.3 0.0 7 80 187 259 180 269 0.90
2 3 9.7 7.3e+03 -1.2 0.0 87 108 330 352 324 362 0.65
3 3 5.1e-14 3.8e-11 44.8 0.0 9 107 381 483 375 486 0.85

Sequence Information

Coding Sequence
ATGAAAACCCTGATTAAGCCAGCCCCTAATCAaCAAATCAACCTTCGTCAAGTTTGCGTAGAGGCTAAGGTCAACGACCAAGGCGTGTACTCACGAGTGACCGTACTTCTGCTCACCAACGTGGGACAGCTTTTTATATGGCAGGACACCACCAACAAACTTACTAGATGCGTATTCGGCCTCGTCCACGAAACAATAATAACAAACGTAGCGCTCACCCACGACGCTCTCTACTTCACAACTAAATACGGCGAAGCTTTCATTGGCACGATCTCGCGCAAGACCACGCCCACGGCGCCCTCGCAACCAATCAAGAAAGAGAAGGAAAGAGACAACAAGTCCTCTCTCGTCAAGTTTTTAGAGAAGGACGACTGTACTTCTGTCAGGATTATGAAGATACCGAATGTTTATAGAGCAGTTTCTATTGCTGTGGATAGTGAAGGACTTAATTTTGCGTGTTTGCAGATAAAACCAACGTGCGGTCTGAAGTCACTACCGCAGCTGTCACCGACAAGTATGTCCAAACATATGGAATCTTTGCGTGAATGCGCCTCCGAAGACGATCTGCTGCATGATGTAGTTTTCAAGGTGGGCACAAAACTCTTCCCCGCGCACATTTTCATTGTTGCCTCTAGCAGCGAACTCCTCTACAAACTGTACCAGGACAACCTATCAGCCCCGGGGGAGAAACCCGAGGTCACACTGGACAACGTTCACCCGGAAGCCTTTGAACGAATCATGAAGTTCATGTATACTGGCACTTGCGATGTCACGGAGTTGGGACAGTGTGGACTTAAGATTACGAAGGAAGAACTGGTGAAGAAGGATAAGGATTGTGATGAGGAAGAAGAGTTGATTGAAAACCCATCAGAGATATCAGCCTTCGAAGTATATAACAAACCTCTGGACAAGTCCAAGCGTCAACGGAACCGTCGCAACACGGACACTCCGCCGCGCACCCATCTGTATTGCGACCCCGTCAAGCTATTGCAGGCCTCCGCCAAGCGACTGCAGGTCATGAGTCTTCATAAGCTGTTGGATAAGTTCTACTACAAGAACGGCTCAATATGTCTGAAAGAAAGCGCGAGCACGAATTTCACCCGGAACCCGTGCCCCAACTGGGAGCGCGAGTCGTTTCCCGAACTAGTCGACACCAGTGTCGTGTCTAAGGACGGCGCGAGAGTGCCCGCGCACAAGTGTGTACTCGCGGCCAGGCTGGAGTACTTCCAGGGAATGTTTATGCATTCTTGGACTGAGagTAAGATGCTGTCAACAGTAACTCTTCCAATTAACTACGGCATCCTGCTGCCAGTCATCAATTTCCTATACACCGACTCATGTCCCGAACTAGAAAACTGTGACAGCATCGACTTCATATGCAACCTCCTTATAGTCGCCGATCAGCTATTCATAACGCGACTGAGAGAAATGTGTGAGATCGCTTTAGCAAACTTAATCAACCTCAAAAACTGCACAGAACTCTGCCAGTTCGGACACACGTACAACGCAACACAGCTCAAACAATGCTGCATGGAATTCATCGCACTAAACCTCAATAGTGTCCTAGAAAACAGAACTTTAGATCAACTAGAGAAAACTTTACTGGACGATATAACTCAGTATTATTGCAAGTTCAACCCCATCATGTCCTCCAGAGTAATCACTCCGTTTTACAACGCTCCTACTGATGAAGTTATTGAAGAATTCGCAAGAACACATCCAGTTAACTTGGAGGTAACAgacgaagatataaaaaatgATGACAGTATAACAGAAATTGTTAAGAAGAAAAAGGGACGGAAGATCGAATACACTGATAGTGAGAAGGAGAGAATGAGGTACGAATCTGTAAGCTCGGTGACGTCATTGGACCTGTCTAATGATACCTCCGGCGATATAACTCTATCTTTGAGTAAGATATCGAAGGAATCGGAGAAGGAAACGCGGTATAAGAAGGAAAAGTGGACCGAGGTACCGTCATCACAGCAGAAACAATTGAAAGTCGTGCAAGCAAGACTGAAAGCCATAAACATTGCGAAGGATTTATTGAATGAAGCGCCTGTCGAATCGTTCACGAAACTCACGAAGAGTAGTTCTTCAAGTGCCATGACAATACAAGAAAAATTACCTAGTTTACCTACCTCATCACAAATGTCTGTCTCACCGAAAGATTCTCCTATATCTGAATCTGCTTGGAGTCCAAAACAGGGTAACGTAGTTATAAGTCATGTGGGACCAAAACTATCtcagaaacaaagaaaaaagttgGCTTTGCAAGGAAATGAAACCGCATCACAAAGTATTGACAATTACTTTACTAAGTTAAATGTGGGTAGTCCGCCTGAAAAGCCGAAGAATCCGTGGAAGATCTGTGTGCCACCGGTTGCAAGCAGCAGCCCTAACTCGAAAGCTATAGAGTTTAATAAGATATTGACTGACCAAAGGAAACAGAAGGAAGATCACTCAAGAATCATGACCAAACCACTACTTTTGACTCAGctTGAAGACAAAGCTATAGAGCAACTTGAGAGATTCTACAACATCCATGAAATAGATGACGAGCTGATCACAGTGCGGCGTATAGAGCTGCAAGTGTCTTCTCCACAATGGTTACATACTGCCCCTAAGTGA
Protein Sequence
MKTLIKPAPNQQINLRQVCVEAKVNDQGVYSRVTVLLLTNVGQLFIWQDTTNKLTRCVFGLVHETIITNVALTHDALYFTTKYGEAFIGTISRKTTPTAPSQPIKKEKERDNKSSLVKFLEKDDCTSVRIMKIPNVYRAVSIAVDSEGLNFACLQIKPTCGLKSLPQLSPTSMSKHMESLRECASEDDLLHDVVFKVGTKLFPAHIFIVASSSELLYKLYQDNLSAPGEKPEVTLDNVHPEAFERIMKFMYTGTCDVTELGQCGLKITKEELVKKDKDCDEEEELIENPSEISAFEVYNKPLDKSKRQRNRRNTDTPPRTHLYCDPVKLLQASAKRLQVMSLHKLLDKFYYKNGSICLKESASTNFTRNPCPNWERESFPELVDTSVVSKDGARVPAHKCVLAARLEYFQGMFMHSWTESKMLSTVTLPINYGILLPVINFLYTDSCPELENCDSIDFICNLLIVADQLFITRLREMCEIALANLINLKNCTELCQFGHTYNATQLKQCCMEFIALNLNSVLENRTLDQLEKTLLDDITQYYCKFNPIMSSRVITPFYNAPTDEVIEEFARTHPVNLEVTDEDIKNDDSITEIVKKKKGRKIEYTDSEKERMRYESVSSVTSLDLSNDTSGDITLSLSKISKESEKETRYKKEKWTEVPSSQQKQLKVVQARLKAINIAKDLLNEAPVESFTKLTKSSSSSAMTIQEKLPSLPTSSQMSVSPKDSPISESAWSPKQGNVVISHVGPKLSQKQRKKLALQGNETASQSIDNYFTKLNVGSPPEKPKNPWKICVPPVASSSPNSKAIEFNKILTDQRKQKEDHSRIMTKPLLLTQLEDKAIEQLERFYNIHEIDDELITVRRIELQVSSPQWLHTAPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00850900;
90% Identity
iTF_00273731; iTF_00274537; iTF_01247236; iTF_00121580; iTF_01085520; iTF_00758389;
80% Identity
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