Dple000978.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Danaus plexippus
Gene Symbol
Hr39
Assembly
GCA_018135715.1
Location
JAEQBL010000025.1:1767409-1775375[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2 2.2e+04 -7.5 12.6 76 192 193 314 53 341 0.64
2 4 3.1e-08 0.00034 20.4 0.1 1 20 418 437 418 443 0.91
3 4 0.00071 7.8 6.1 0.0 74 128 460 512 441 534 0.68
4 4 1.3e-64 1.5e-60 206.1 0.0 204 408 530 735 517 735 0.94

Sequence Information

Coding Sequence
ATGTCTAGTGAGGGGGAGGCGGTGAAAGTGGAAGGGGGTCATATCTCCGTCACTACTATCAGCATGTCGGGACCGGAGAGTAGCAATGGGCAGTTCTCGTATAGCTCGAGCGGAGTCCGTATCAGCGTGTCCTCGGAGCCTCAAGACGAGGATTCGACGGACGCGGAAATATCCAAAATAGATTTCACCCAACACCAGTATGAGGTCAACATGCGGAATAAGAAGAAGCGTTCGTCCGGCCAGTGTGACCAGGCCAAGGAGCAAGAGAGGCCGATGTCCTGGGAGGGAGAGCTGTCAGACTCGGAAATGGTCATCGACACCAGCACCAATAACGACGAGAACAGCAGCTCCCTGGACCTCCAATCCTCCCGGGATTCAATCGACACGCTCCGTAACGTGTCCATTAAGACTGAACCTCTTAAAACAGAGCTCTTCCACACTATGGAGGACCAACGTGTTCTGGACCTGAAGTATACCGTGCCTCTTCAGTCACATCAGCGCAGTCTTAGTATGAATAGGATATCGGTCCTAACAGACAGTAATTCGTTGTTAGCGCGGCGGCCGTCATCACCCTCGCACTACGACGCGCATCCCGAGGTCCAGAACCTCACTATCAAGAAGGAACAGCTCTCTGAACTCAAGTCCGAACCGACGTCCAGTGTGGACAAGCTGCTAGGGCTCCACGGGTCCCCCCTGATGGGACGCCTCCCCCGCGTGCAGTCCAGCGCCAGCACTGACTCCGCGGTACACTCAATGTATACACACAGTGTATACAGCAGTCCGTCGGCCAGCCCCCGCCCCTCGCGCCACTACACCCCCTCCCTCTCCCGGAACAACAGCGACGCGTCACACTCCTCATGCTACTCCTACAGCTCAGAGTTTTCCCCCACTCACTCTCCAGTACAAAGTCGTCACCCCCACGTGGTGTACCGCGAGGCGGCCGTGTTCCCCGCCTCCCCCGCTCATGATGAGGACGCGGACGGAACCGACGACAGGCTGCATCATCACCAGGGGATCAGCCGCCAACAACTCATTAACAGTCCGTGTCCAATTTGCGGCGACAAAATCAGTGGCTTCCACTACGGGATATTTTCTTGCGAGTCTTGCAAGGGCTTCTTCAAGCGGACGGTTCAAAATCGCAAGAACTACATGTGTCTGAGAGGCGGGAACTGTCCCGTCACCGTCGCCACCAGGAAGAAGTGCCCCGCGTGTAGATTCGATAAGTGTCTGGGATGCGGGATGAAACTCGAAGCTATAAGAGAGGACCGCACCCGCGGCGGTCGGTCTACTTATCAATGTTCGTACACGCTGTCTGGCGCGGCCTCCACCGGCTCCTTACTATCAGCGCACACTCCCGCAACGCTGAGACACGCCTCGAGTCTCACATGTGTGAACGGTCCGGGCTCCTACAACAGAGGCGAATCAAGCAACAGTCGACTCACCCCTGACATACCGCCGTTATTGCAGGAAATAATGGACGTGGAACATCTATGGCAGTACAACGAGTCCGAGCTGAGTCGTATGAGCAAGAGCTCGAGCAGTCCGTCCGCCAACCCCCTGTTAGCGGCCAGCGGCATCACGGCGCAGAACTCTAGCGCCGACTTCCTGGCCGACCTGTGCAATATAGCAGACCACAGATTATACAAGATCGTCAAGTGGTGCAAGAGTCTGCCGCTCTTTAAAAATATCTCCATCGACGATCAGATATGTCTGTTGATAAACAGCTGGTGCGAGTTACTGGTGTTGTCCTGTTGCTACAGAGGAGTCAGCACGCCAGGGGAGGTGCGGGTGGGGGGAGGCAGGGGAATAACGCTGCAGCAGAGCGCCAAGTACGGCCTAACTCCATGTATTGAACGTATGTTGAGTTTCACTGATCACTTGAGGAGGCTGCGTGTGGACCGCTACGAGTACGTCGCGCTCAAGGTCATCGTACTACTCACTTCAGATGCTCCAGAGCTTCATGAAGCAGAGAAAGTGAGAGCTTCCCAGGAGAAGGCGCTGGCAGCCCTACAGGCCTACACCGCCACACACTCACCAGACACACCTGCCAAGTTTGGTGAACTACTGCTGCGAATTCCAGAACTACAGAGAACTTGCCAGTTTTTCATGCAAGTCGGAAAAGAAATGCTCAATCCAGCGAACAAGAGTAAGGACGGAGAGGGACCGAGCTTCAACCTCCTCATGGAACTGCTTCGAGGAGATCATTGA
Protein Sequence
MSSEGEAVKVEGGHISVTTISMSGPESSNGQFSYSSSGVRISVSSEPQDEDSTDAEISKIDFTQHQYEVNMRNKKKRSSGQCDQAKEQERPMSWEGELSDSEMVIDTSTNNDENSSSLDLQSSRDSIDTLRNVSIKTEPLKTELFHTMEDQRVLDLKYTVPLQSHQRSLSMNRISVLTDSNSLLARRPSSPSHYDAHPEVQNLTIKKEQLSELKSEPTSSVDKLLGLHGSPLMGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRPSRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHPHVVYREAAVFPASPAHDEDADGTDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHTPATLRHASSLTCVNGPGSYNRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELSRMSKSSSSPSANPLLAASGITAQNSSADFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLQQSAKYGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELHEAEKVRASQEKALAALQAYTATHSPDTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00985246;
90% Identity
iTF_00419062;
80% Identity
iTF_00421447;