Dmel046625.1
Basic Information
- Insect
- Danaus melanippus
- Gene Symbol
- -
- Assembly
- GCA_010014825.1
- Location
- JAAAKD010000187.1:16882-21019[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 3.3 6.1e+02 2.9 0.2 1 23 155 180 155 180 0.87 2 22 1.3 2.4e+02 4.2 0.3 1 16 226 241 226 246 0.85 3 22 0.92 1.7e+02 4.6 0.6 6 23 260 278 260 278 0.96 4 22 0.008 1.5 11.1 0.0 1 23 287 310 287 310 0.95 5 22 1.1e-06 0.00021 23.2 1.3 2 23 335 356 335 356 0.97 6 22 9.2e-05 0.017 17.2 2.0 1 23 363 386 363 386 0.96 7 22 0.058 11 8.4 0.0 1 23 392 414 392 414 0.95 8 22 5.9e-05 0.011 17.8 0.9 1 23 420 442 420 442 0.98 9 22 0.0016 0.29 13.3 7.5 1 23 448 470 448 470 0.98 10 22 0.089 16 7.8 3.4 1 23 590 612 590 612 0.96 11 22 5.8e-05 0.011 17.9 2.8 2 23 619 641 618 641 0.91 12 22 6.5e-08 1.2e-05 27.1 3.2 1 23 647 669 647 669 0.99 13 22 1.4e-06 0.00026 22.9 4.4 1 23 675 697 675 697 0.98 14 22 0.00013 0.024 16.7 2.2 1 23 703 725 703 725 0.97 15 22 0.00019 0.034 16.3 4.8 1 23 731 753 731 753 0.97 16 22 0.00024 0.044 15.9 4.1 1 23 759 782 759 782 0.96 17 22 0.028 5.1 9.4 0.3 2 23 848 868 847 868 0.83 18 22 4.7e-06 0.00087 21.3 0.1 1 23 876 899 876 899 0.98 19 22 1.3e-05 0.0023 19.9 1.8 1 23 905 927 905 927 0.96 20 22 7.7e-05 0.014 17.5 0.4 1 23 933 955 933 955 0.98 21 22 0.00079 0.15 14.3 0.1 1 23 961 983 961 983 0.97 22 22 0.0035 0.63 12.3 0.3 5 23 992 1010 991 1010 0.97
Sequence Information
- Coding Sequence
- ATGAACGGTGGAACGGCATCAGACCAACAAGATAGACTCGAAATCAAATGCAGCGGCGGAAATCATGAGAACCTGCAGGATTCTCCAAATATATGTCGAATATGTGCCACCGTCACGGACCTGGTCATTCCTATATTTGAAGGGGAAGGACTACAAAATGACTTAGCTGATAAAATTCATAGACATTTACCTATaaagGTGTCGGTGCAGGATGTGCTGCCCCAGGTAGTCTGCTACCAGTGCTCCAGTACTGTGCTCGCCTGGCATGAGCTGGTGCAATGCTGTCAACAAGCTGACCAAGCTCTCCGACAGCACGCAGCCAATAGGAAGAAGAAGGCCAATGAAGTAACACAAACACCGTCACATCTAAAGGGTTTGAACTTATTTACATCCACAGTGAGAGATGCGTTGAATGATTACTGTCAAATGCTTAACATAAGTCAGGAAAACTCTGACATATGTTACGTCTGTCAAGAATGTGACGGACATCCTGTATCAAGGTCTATGGAAAACTTGTCGCAGCATCTGCAATTGGTCCACAGTGAATTGAGTAATGAGgaacaaattgaaaaatttataaaaaacaatattttcatagaGGAAGTCCTCGTCTCTGATGAATTATTTGGTAGCGATGACCTCAGTGAGCATGCCCCTAAGAAAGAATTACCAAATTATTCTTGTCCCTTTTGTGAAAGCATGTTTTCTTCACCCACTAGACTTGTATTCCACCTGAACTGTCACCTCGAGGTCTGTATCGAGGACGGAGTGTACTGTTGCGACCAActgttcaataataaaacatctttCGTCACTCACCTACAATCTCAACACGTTCGTAAAGTTATCGAATCGTCTTATGTGTGTAAGAGCTGCGGTCTCACAGCCGGCGACCTCGCCGACCTCCAGAGGCATATAAACGATAATCATCCCGAAGCGGAAGATAGGTATGAGAAGAACAAGACAGAAGGCAGTCCCAAATGTCAGAAATTTATTCCGGCCGTGTGTTCCGAGTGCAACAAAACATTCTCTAACAAGTACAACATGTTAGTGCACATGAGGAACCATTTCGGACAACCGAGTCGGTTCGCATGTGACAAGTGCAATAAGACTTACAAGAGCCAAGGCAGCCTCATATACCACCACAAGGTCGTCCACGAAGGACAGCTCAAGTTCGTGTGCTCGTCGTGCGGAGAGGCCTTTCCGTCAAGAGCAGCAAAAGACGTACACGCGCGCCTCCACACTGGTCAGAGACCTTTTTCATGCCAATACTGTGGGAAGGCCTATCGAGCTAAGAACACTCTGTACCGACACATAGACATGCATCTGAACATAAGGAAATATGCCTGCAACTTGTGTGACAAGAAGTTCCGAAAGAGTACACATCTTAAATGTCACTTGCGAACGCACGAGAGAACGACCTATGATACTGAGCCAGTCAGAGGTCATCGCAGGCACAGACCGGATTCCGACGAAGACGACAAACCTCTAGCGGAGTTCGCGGCCGGGAAACAATCAGATGTATACAGAAACTTTTATAGGGCATTAACAACGTTTCGAGATCACTACGTTCAACATGAGAATAAGAGAGATCGCTGTTCAGATCTATCGAACTCGAGCGATTCGGAGGAAGAAAGGAAGTGTGAAGAACTGGATCCGATTCAGTACGACGACCTCTCCAACACCAACATGAGAAAGGACAAAATGAACGAGGAGACGCGACTCGAGCTCAGCCAGGTGCAGGCGAAAATAAACGGGAAGACTTACTTCATCTGCAAAATCTGTGACAAGAAGCTGAGCTCCTCACACACTTATATTTTCCACAAGAGAATACACACGGGGGAGCGACCGTGCATCTGTCACGTGTGCGGCAAACAGTTCCGCACGCCCAACGGACTCCAGCGACATCTCACCGAGACGCACGAACGACTGCGCCGGTACACTTGTCAGATTTGTCACAAGTCCTTCGCAAACTCGCAAAATCTCAAGCAACATATGAGAATACACACGGGCGAGAGACCTTTCGTGTGCTCCCACTGTGGCAAGCGGTTCACACAGAGTGGCTCGCTACATGTGCACCTCAAGACACACAGTGCCACGCTCCCGCACGTCTGCAGGGACTGCGGCGCGAAGTTCCGTATGCGCTCCGGACTGACACGGCACCGCCTCAAACATACCGGAGAGAGGCCGCACGTCTGTCGGCATTGCGGAAAAGGATTTAGACAAAAACATGAGATGAATGCGCACGCCCTCACGCACTCGGACAGCAAACCGCACGTTTGCACCGTCTGCGGAACTGCCTTCCGCCAACGACGGGCGCTCCGCCATCACTTCAAACGACTACACGACAGCAAGCCCGGGGAAGACGCACACGTCTACAACAACGCGATCAATTACATTCTGACATTGAACTCTGTCGGAATAGAACATGCGCCCTCCGCCACGGAAGACGAAGTAAGGCTCTGCGACGTGGTAATCGATCGACCGGAAGACTGCAAGGAACTGCCGCAAAATATAGAACAAGAGAACAGCGACAGTAGCGAGTGCAGCATTTGCGGCAAGTCGGTGACTCGCGCGAGTAAAGCGCGGCATAGACGTGCGCACGAAGCAGCGGGCACACAACGCTACCGCTGCAGCGTGTGCGGGAGTGCCTTCTCAGACGGCGGCAACCTCGCTCGCCACATTCGTACTCTGCACACCGAGCGTCGACCTCACGCGTGCCCTCTCTGCCGCCGAACCTTCACGCGCGCCGCTCACCTCGCCGACCACTTGCGGTCACACGACGATCGCAGGGACTACGTGTGCCACGTGTGCGGGAAAGCGTCCAAGACCGGAGCCGGACTGCGCTCACACCGCCGCGTACACGCCGAAGAATTTGAATTCGAGTGCCCGGTCTGTTCGGCGCGTTTCAAAACAGGCCGCCAGTTACGCGCGCACGCCTCTGTACACACGGGTGAAAGGCCGTACGCCTGCATCTGTGGAGCCGCCTTCCGTCTGCGAGCTCAGCTCACCAGGCACGAGCGTACTCACACACGAATGAAAACAATCGTCGAATGA
- Protein Sequence
- MNGGTASDQQDRLEIKCSGGNHENLQDSPNICRICATVTDLVIPIFEGEGLQNDLADKIHRHLPIKVSVQDVLPQVVCYQCSSTVLAWHELVQCCQQADQALRQHAANRKKKANEVTQTPSHLKGLNLFTSTVRDALNDYCQMLNISQENSDICYVCQECDGHPVSRSMENLSQHLQLVHSELSNEEQIEKFIKNNIFIEEVLVSDELFGSDDLSEHAPKKELPNYSCPFCESMFSSPTRLVFHLNCHLEVCIEDGVYCCDQLFNNKTSFVTHLQSQHVRKVIESSYVCKSCGLTAGDLADLQRHINDNHPEAEDRYEKNKTEGSPKCQKFIPAVCSECNKTFSNKYNMLVHMRNHFGQPSRFACDKCNKTYKSQGSLIYHHKVVHEGQLKFVCSSCGEAFPSRAAKDVHARLHTGQRPFSCQYCGKAYRAKNTLYRHIDMHLNIRKYACNLCDKKFRKSTHLKCHLRTHERTTYDTEPVRGHRRHRPDSDEDDKPLAEFAAGKQSDVYRNFYRALTTFRDHYVQHENKRDRCSDLSNSSDSEEERKCEELDPIQYDDLSNTNMRKDKMNEETRLELSQVQAKINGKTYFICKICDKKLSSSHTYIFHKRIHTGERPCICHVCGKQFRTPNGLQRHLTETHERLRRYTCQICHKSFANSQNLKQHMRIHTGERPFVCSHCGKRFTQSGSLHVHLKTHSATLPHVCRDCGAKFRMRSGLTRHRLKHTGERPHVCRHCGKGFRQKHEMNAHALTHSDSKPHVCTVCGTAFRQRRALRHHFKRLHDSKPGEDAHVYNNAINYILTLNSVGIEHAPSATEDEVRLCDVVIDRPEDCKELPQNIEQENSDSSECSICGKSVTRASKARHRRAHEAAGTQRYRCSVCGSAFSDGGNLARHIRTLHTERRPHACPLCRRTFTRAAHLADHLRSHDDRRDYVCHVCGKASKTGAGLRSHRRVHAEEFEFECPVCSARFKTGRQLRAHASVHTGERPYACICGAAFRLRAQLTRHERTHTRMKTIVE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00419906;
- 90% Identity
- -
- 80% Identity
- -