Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.015 3.3e+02 1.8 0.3 25 37 118 130 107 141 0.72

2 5 0.017 3.9e+02 1.6 0.0 22 45 145 168 138 175 0.79

3 5 0.00012 2.8 8.4 0.1 22 46 173 197 167 200 0.89

4 5 8.8e-06 0.2 12.1 0.1 21 52 200 231 196 231 0.88

5 5 0.00046 10 6.6 0.0 21 48 228 255 226 259 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.015	3.3e+02	1.8	0.3	25	37	118	130	107	141	0.72
2	5	0.017	3.9e+02	1.6	0.0	22	45	145	168	138	175	0.79
3	5	0.00012	2.8	8.4	0.1	22	46	173	197	167	200	0.89
4	5	8.8e-06	0.2	12.1	0.1	21	52	200	231	196	231	0.88
5	5	0.00046	10	6.6	0.0	21	48	228	255	226	259	0.89

Coding Sequence: ATGGAAAATGCTCAAGAAAGAGATTTTCATAGAACTTTGGAGCCTGACGTGATCATTAATCATGAATCTAGTGAAGATGAGGAAGATATTAGCATCAAAAGCAAATCATGTTGTCCCTCGGCTAACAAGAGCCTTCAGTCGGCAAAATCTCAACCAGACATATCTATAATCcccttaaataaaaaatctcaaatcaaAATAAGACTATTTAACAAAGAATATTCCCCGTCAAAGGACGATGTAAAAGTACAAATCATCTCTCGATCTCCTCGACAAACGGTAAGACTGGTATCAAAAGACGAAGCGGAAAGCGCAGGTGAAACCTACGCTCGACGAAAATCACTTCCTCTAGAAAAATGtccaatttgtaaaaaatactttcgTCGAATGAAAActcatttattaaaacatgAACATACTAATCGAAATCCTGACGATCCTCTTACGTGTACGTTTTGTATGAAAGGTTTTAATACTCAGAGTAATTTACTCATTCATATGAGGACACATACTGGGGATAAACCGTATATTTGTGAAGTTTGCCATAAAGGATTTGCTCAGTCGTGTAATCTTGTCAATCACTTGAGGATTCATACGGGAGAAAGACCATTTAAGTGTCCTCATTGTGATAGAGCTTTTACACAATCAGGTAATCTTAATAATCACATAAGGCTGCATACTGATGAAAAACCGTTCAAGTGTCACTTTTGCGATAAAGCATTTGTTCAATCGGGGAATCTCAATTCACATATTAGGAACAATCACAAATTTGTTGAGGATGTTTCTAAAGATATTAGTGAAAAAGGCGATGACTGCAAGTGCTAG
Protein Sequence: MENAQERDFHRTLEPDVIINHESSEDEEDISIKSKSCCPSANKSLQSAKSQPDISIIPLNKKSQIKIRLFNKEYSPSKDDVKVQIISRSPRQTVRLVSKDEAESAGETYARRKSLPLEKCPICKKYFRRMKTHLLKHEHTNRNPDDPLTCTFCMKGFNTQSNLLIHMRTHTGDKPYICEVCHKGFAQSCNLVNHLRIHTGERPFKCPHCDRAFTQSGNLNNHIRLHTDEKPFKCHFCDKAFVQSGNLNSHIRNNHKFVEDVSKDISEKGDDCKC

Sequence clustering based on sequence similarity using MMseqs2