Basic Information

Insect: Cylas formicarius
Gene Symbol: MBD-R2
Assembly: GCA_029955315.1
Location: JARGXY010000001.1:42082583-42093523[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.9e-16 1.6e-12 47.2 0.0 8 74 412 477 406 480 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.9e-16	1.6e-12	47.2	0.0	8	74	412	477	406	480	0.92

Sequence Information

Coding Sequence: ATGGGTCGTAAATGTAGCGTGGAAAGCTGTAGTTCTGACTCGAACCGTGCTGAAGATACGGGCGTGACATTTCACAAGGTGCCTCTTCATAACGACCTGCGCCCCAAATGGATTTCGCTTTGTCGCATTCCCGAGGACAAGAAAAGCGTAAAAGTCATCTACGTTTGCTCCCGACACTTCTTGCGAGCTGACTTTTGCCACTTCAAAGGCAAAAAGTACATGCTTAAGCACGGTGTATTACCAAGTGTGTTCCCTTGGGATAAGTCAAAATTGGAAGCCCTAAAGGCCGAAGCTGCCGTCAAAAAGGAAACAAACGTGGATAAAAAGAAACCGAAGAAAGGGAAAAACAGTCACTCAAAGGGACAAAAAGTTGAAAGTAATATTGAAATTGAGACAAAATTGAATGAGAAGGTAGACGGGAGCGACTTTGTAGTAAAAGAAGAAGCAACAGAGGAAAGTGAAGAAGTAAAGGACTTTGATGAGCAGCTGAAGATAGCCCAGACTTCTGCTGCTAAAACAGAGGAAGCAAATATAGGAAGTTCCAGTCacataaattttactattaattcTCGAATAGAGGTATTAGACAATAATAGCTTTTGGTATCCCGCTAAGATAACTGAAGTTGACTACGAGGAGAATGAAGTTTTGATTCATTTTGAGAAGTTCTCCAGCAAGTATGACGAGTGGATACCAATGAACAGTGCTCGACTCAGACCAGTTCAAGCCAAACCTATACAGAAATATGAAATTGGGGAAAGGTGTATGGCTTCGTGGAGTGATTCGCGTAAATTTCCGGCCACAATTACCAAGACGCTAATGGAGGATACTTACGAGGTGCTATTTGATGATggatttgtgaaaattttaaagcaGCATCGCCTGTCCAAGATGCAAGCGGGAAAACCGAGCCAGGCATCTCCACTCTTTGACCCAATCAAAAGCACCAAACAAGAGAGACGAGACAGAAAAAGGAAACTTAATGTGGCCGCTTTGTTTCGGAAAAGACCACGGCTCTCCTTAAATGAGGATAAAAAGGTCAAGGATGTCAAAGAACCGCCGGCGGAAGAATCACCTGCCGCCGCCGCCCCCTCCGACGCAGTTTCTTCTCCGCCATCTTCGCCCGCCGAAGACCCAACCAACTGGCACCCAAAGTGGCTGAATGGCAAGCCGGTCGGTACCGAGTCCACGATCGAAACCATCGACGGTGTACGCAAGTCCATAATAGTGCCGGATCCTCGTCTGCCCGCCGGTTGGTTCAAGCACCTGTGTCAGAGGCAGCATGGCTCGTCGGCGGGCAAATGGGACACGATCATAAAATCGCCGGACAACCGGCGATTCCGTTCGCGTACAGAAATCCGGAACTATCTGACCGCCCACCCAGATATCGACGTGGACTTTGACCTGTTCGACTTTAGCATTTACCGGAACAGCCGTCGGAGGGCGTCCAAGCCCAAAGACGCTGAAGTCTTGTCTGCTGCCGAACCGCCTCTGCCTCCTCCATGTCAGCCCGAGAccgaggaggaggaggaggcgATTCCAGACGAGCCCGCCCTAAAAATCGCGTTCGAGGACGATGCATACAAGTGCCCAATCGAAGGGTGCGGTAAGAATTTCAGGCGTGAAAATTTAGCGCTGATGCACGTCAAGCATTACCATCCGGAGTACTCCAAGTATCTCGAGTCGACGCCGAACGTCGCGGATCTGGCGTACGCGCGCACTGTAGGAGAGAGTTTGGACTCGTCCCCAGGGCCAGTCAAGGTAGCAGTCGCCGTGAAGCCGCAGGTCCAAGACAAGGCGCCGGGAACTCCGAGGCCCGAGCACAAGCCTGCAAAGGACGCGGAATTGATCAAAATCCTGAACCAGGCCTTGGGTGACGACAAGAGTTCCGATATCAAACCGAAAGACCTGGCTGACCAACTAGCACCGGGTAGCCCATATCCGGACATTAAGCTGAAGGATCTGCTCGAAGACACAATAGTCCCCAAGAGGGACGAGGTTCCTCCTCCTCCGCCGCCCAAGTCCACGATAAAGACGCTGCTACCTAAGTTACCGCCCGCACCTTCGGCTGACCTGCCGTTGGTCGACCACGCATCGCCAGACCAACTCCCACTTACGGAACCCGCTTCACCTCCCCAGCAGGACGACGAGCAGCACCAGTCCTTCGACGGCATCATCATCGAGGGCGGCAAAATCATCAAGCTCGAGCGCATGAAACAGGAGGAGATCATCAACTGCACATGCGGCTTCGCTGAGGAGGACGGCTTGATGATACAGTGCGAGCTGTGCTTATGCTGGCAGCACGCGTACTGCAACAATATCCAGCGCGAAACCGAGGTACCAGAGAAGTATGTGTGTCGCATCTGTCAGAACCCTTGGAGGGAGCGAGGGTCGATGCGATGGCTCCATGACCAAGAGTGGCTCAAGCAAGGTACTTTGCCCACCTCGTCATTTCACGCCAAGGACTCGGAAGTGGCGCACGCGCGTTTCGACAAGCTGAAACGCAGTCACGACGTTACCGGCGGGCTGCTCGAACTGAAGGAGTATCTCCACGCCTTGTCGCTGAAGCTGATGATCGCCGAAGCGAAGAACCACCCCAAGTTGTACCTGTGGTCAAAGCCGTGGGACAAGCCAAGGTTGCCAGAGAAATCAGATGCCATCTTGCAATCGGCATCTGCGACGAAACCGAAGCTGGAAAACGGCGACCACCAGTACATAAAGAACGAACTGGGTGTGGAAAAACCGGACCTATCGAACGAATCCATGCTGATGATGATACTCAAAGCGGGCAAAGAAGATATCGCATTGCCCAATGTGCAGCAGAACTCCGCACCTATCATACCTCGACCAGAAGCAGCCATAAACTTAGACGACTGTCGCCTAAACTTACTGGATCACATATCGCATTCGAGTTCACTGATAGAAGAAAGGCTCGACCATTTCGAGAAACAAATCGTCGAGCTTGAAGCCGGAACGGAAGGGGATCCGGACGAAGAATGCGCGAAGACTAGGCAGACGATCCAGATGCTGCTCAGAGATTTGGACAAACTGAAAGCGTTCAGCCAAGTCCCAATGGGTTGA
Protein Sequence: MGRKCSVESCSSDSNRAEDTGVTFHKVPLHNDLRPKWISLCRIPEDKKSVKVIYVCSRHFLRADFCHFKGKKYMLKHGVLPSVFPWDKSKLEALKAEAAVKKETNVDKKKPKKGKNSHSKGQKVESNIEIETKLNEKVDGSDFVVKEEATEESEEVKDFDEQLKIAQTSAAKTEEANIGSSSHINFTINSRIEVLDNNSFWYPAKITEVDYEENEVLIHFEKFSSKYDEWIPMNSARLRPVQAKPIQKYEIGERCMASWSDSRKFPATITKTLMEDTYEVLFDDGFVKILKQHRLSKMQAGKPSQASPLFDPIKSTKQERRDRKRKLNVAALFRKRPRLSLNEDKKVKDVKEPPAEESPAAAAPSDAVSSPPSSPAEDPTNWHPKWLNGKPVGTESTIETIDGVRKSIIVPDPRLPAGWFKHLCQRQHGSSAGKWDTIIKSPDNRRFRSRTEIRNYLTAHPDIDVDFDLFDFSIYRNSRRRASKPKDAEVLSAAEPPLPPPCQPETEEEEEAIPDEPALKIAFEDDAYKCPIEGCGKNFRRENLALMHVKHYHPEYSKYLESTPNVADLAYARTVGESLDSSPGPVKVAVAVKPQVQDKAPGTPRPEHKPAKDAELIKILNQALGDDKSSDIKPKDLADQLAPGSPYPDIKLKDLLEDTIVPKRDEVPPPPPPKSTIKTLLPKLPPAPSADLPLVDHASPDQLPLTEPASPPQQDDEQHQSFDGIIIEGGKIIKLERMKQEEIINCTCGFAEEDGLMIQCELCLCWQHAYCNNIQRETEVPEKYVCRICQNPWRERGSMRWLHDQEWLKQGTLPTSSFHAKDSEVAHARFDKLKRSHDVTGGLLELKEYLHALSLKLMIAEAKNHPKLYLWSKPWDKPRLPEKSDAILQSASATKPKLENGDHQYIKNELGVEKPDLSNESMLMMILKAGKEDIALPNVQQNSAPIIPRPEAAINLDDCRLNLLDHISHSSSLIEERLDHFEKQIVELEAGTEGDPDEECAKTRQTIQMLLRDLDKLKAFSQVPMG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00413604;
90% Identity: iTF_00413604;
80% Identity: iTF_00413604;