Basic Information

Insect: Cydia strobilella
Gene Symbol: -
Assembly: GCA_947568885.1
Location: OX387696.1:8418519-8451579[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 6.4e-10 2.5e-06 27.6 0.1 7 50 201 246 197 251 0.84

2 7 6.4e-10 2.5e-06 27.6 0.1 7 50 253 298 249 303 0.84

3 7 6.1e-10 2.4e-06 27.7 0.1 7 50 305 350 299 355 0.84

4 7 6.4e-10 2.5e-06 27.6 0.1 7 50 357 402 353 407 0.84

5 7 6.4e-10 2.5e-06 27.6 0.1 7 50 409 454 405 459 0.84

6 7 1.8e-09 7e-06 26.2 0.1 7 48 461 504 455 506 0.84

7 7 1.2e-13 4.7e-10 39.5 0.0 7 70 579 640 575 645 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	6.4e-10	2.5e-06	27.6	0.1	7	50	201	246	197	251	0.84
2	7	6.4e-10	2.5e-06	27.6	0.1	7	50	253	298	249	303	0.84
3	7	6.1e-10	2.4e-06	27.7	0.1	7	50	305	350	299	355	0.84
4	7	6.4e-10	2.5e-06	27.6	0.1	7	50	357	402	353	407	0.84
5	7	6.4e-10	2.5e-06	27.6	0.1	7	50	409	454	405	459	0.84
6	7	1.8e-09	7e-06	26.2	0.1	7	48	461	504	455	506	0.84
7	7	1.2e-13	4.7e-10	39.5	0.0	7	70	579	640	575	645	0.87

Sequence Information

Coding Sequence: ATGTCTGACGAAATGGCGGTTAGTGATAACCCGAGTGGGGAAGAAGCCGTCGTTAATGGACCTGAAGCGTTGGCAGCGAGTGCCGAGGTCGCGGCGCCGGAGGCCCACGATGCTCCCAGTGCGCCCGCGGACCCGGAGCCTGAAGAAACCAAGCCAATTAAACTAGAACCTGAATGGAAATCAGAAAATGCTCCAGAGCCCGCAGAAGACACAGATGACAAACGGGGTGTCAAACGCAGGGCGTCAGCGGCTTTCAGCAATGCTGCTGGTGAAATCTTCAAGCCCTTTAAGGGCTTTGCGAAGATGGAGCTGGATGACTCTATTGTGGATTACAAGAAAGTTCTAGACAACCTGGAGGCAGAGGTGGTAGAGACCAGCAAAACCGTGGTGCCTCTCCGGACCGTGATGGGGACACCCACAGCTCCGGCCAGGGCCAGTAAGCGAGCGAGGCAGGATACAGATGGATCGAGACCCTCATCAGCCCTGTCGTCTAGGTCTGAAGACGGAGTATCTTCCACTGAGTCGCTATTGGTTATCCGCCAGGTATCCTCCCCGTTGGTCCGGGGCCGCCGCGCCACCACCGAGATGTCGTCGCCACTGCTCCGGGTGCCGCTCGAGAAGGGCTGGAAGCGGGAGCTGGTGTACCGAGCCGCGTTGGATCAGCACTCGCGGCGCAACGCAGACATATACTACTACACGCCAAGCAACAAGAAGCTGCGCTCCACTAGAGAGACGGTATATCTGTCGTCGCCACTGCTCCGGGTGCCGCTCGAGAAGGGCTGGAAGCGGGAGCTGGTGTACCGAGCCGCGTTGGATCAGCACTCGCGGCGCAACGCAGACATATACTACTACACGCCAAGCAACAAGAAGCTGCGCTCCACTAGAGAGACGGTATATCTGTCGTCGCCACTGCTCCGGGTGCCGCTCGAGAAGGGCTGGAAGCGGGAGCTGGTGTACCGAGCCGCGTTGGATCAGCACTCGCGGCGCAACGCAGACATATACTACTACACGCCAAGCAACAAGAAGCTGCGCTCCACTAGAGAGACGGTATATCTGTCGTCGCCACTGCTCCGGGTGCCGCTCGAGAAGGGCTGGAAGCGGGAGCTGGTGTACCGAGCCGCGTTGGATCAGCACTCGCGGCGCAACGCAGACATATACTACTACACGCCAAGCAACAAGAAGCTGCGCTCCACTAGAGAGACGGTATATCTGTCGTCGCCACTGCTCCGGGTGCCGCTCGAGAAGGGCTGGAAGCGGGAGCTGGTGTACCGAGCCGCGTTGGATCAGCACTCGCGGCGCAACGCAGACATATACTACTACACGCCAAGCAACAAGAAGCTGCGCTCCACTAGAGAGACGGTATATCTGTCGTCGCCACTGCTCCGGGTGCCGCTCGAGAAGGGCTGGAAGCGGGAGCTGGTGTACCGAGCCGCGTTGGATCAGCACTCGCGGCGCAACGCAGACATATACTACTACACGCCAAGCAACAAGAAGCTGCGCTCCACTAGAGAGAGACTCGGCCTGTTCGTCCCGGTGTGGCGTCCCTGTCCCCCGGGCCTGAGCGCGCTGCCCGCGCGGCGCCCGGCGCGCCTCTTCGCGGGGTGCCCCGCGCGCACCCGCCGCGCCGCTAATTCGCCCACGGCTCGGGCACTGGAGCTTCTTAATGTCTTGTCCATCCGTGCCCCACAGATCGACATATTCGCGGATAGTACGGTATATCTGTCGTCGCCACTGCTCCGGGTGCCGCTCGAGAAGGGCTGGAAGCGGGAGCTGGTGTACCGAGCCGCGTTGGATCAGCACTCGCGGCGCAACGCAGACATATACTACTACACGCCAAGCAACAAGAAGCTGCGCTCCACTAGAGAGGTGGCGGAACACCTCTCTGGGACCGGACTGACTTTAGACAACTTTTCATTCTTCAAGGAACCACTGGGTGTAGATGACCCAGAAAAAGAAATCATTCGTGACGCGAAGCTGATGCGGAAGGTGGAGTCCCCCGTGGCTCAGACGGCGCCCCCCTTGGCGGAGGGCAAGCGCACGCCGAAGCCCAAGCCGCCCAAGGGCGCCAGCCCCGACCCGGTCACTCCAAAGTCCAAGTCTCCGCTGGCCAAAATCAAGGTGAAGTCAATGCAGCCGCGCCTAAACCGCACGCCCGCCGCGCCGTCCGCCAAGAAACCCGCCGCCTCACCCGCCTCCGCCACCGCCACCGACAACAACAACACGCAGGCCATCAAGAAGAACAGAACGGCGCCGCCGGTCCCTGCCGTCCCGGTCGCGCCCGTCCCGGTGCCGGTCGCTGTGCCGGTGCCGGTGCCGGTCATGCCGGTGCCGGTGCCCGTGCCGGTCATGCCGGTGCCGGTGCCCGTGCCCGTGCCCGTGCCGGTGGCCCCGGCGCCGCCGCCGCTGCAGAGCCGGCCGCCGGTGTCGCCGGTTGACGCGAAGATTGAGCAGCATGACTTGTCCTCACCCCGACAGTTGGTGCAGCCATGCTCCATGACATGCGGTCGCGGAGTGCCCACGCTGGCCTGCGGGCTGTGTCTGTGTCTCTACCACCCCGCCTGCGCCGGTCTCACGGCGCCACGACCCGAGGGGACCTTCTTTTGCAAGAACTGCCGAAAGTCCAGTTCGCCGTCATCATCCCCGCCGCCGCTGACCCACAAGTCCGGGCTGACGTCCCTGGTGGCGCCGTGCGCGCGCCGGCCCGCCCCCGCGCCCCGGCCCCGCCCCCGCCCCCGCCCCTCCACCGCCGCCCCCTCCACCGCCGCCGCCGCACAGCCGGCAGACAAACGAGTCACGCTCAGAATGAAGATGGCAGGCGGGCCCGGCGGCGCTCGCGTGTGGGCGGTGTCACCTGCGCGTGGCTCGCTGCCGCAGTCGCTAGCCGTGCTCAACGGACGCCGCTTCATCGTCGTGCCGAGGGCTATAGTGCAGCCTGCTCCCAGTGACTCGAAACCAGTTCGAGGCCGAGTGGCGAATGGTGCCGCGCCGTCACCCACCACCGACTCGCCGCGGCGAAGAGGGAGACCCAGGCTAGACGAGAACACCGACCACTTCACTGCCTTCTGCCAGAAGGCGAAGGAACACAACTATAATGTGGCTAAACAGATATTCCAATACCTGGGCATGCGTGACCTGGCGCATTGTGCGCGCGTGTGCCGACTATGGCGGGAGCTGGCTGCCACGCCACAGCTCTGGCGGCACGTTAGGATGAAAAATTCACACGTGAGTGACTGGGGAGGTCTATTCGCGGCTCTACGGCGGCACGGCACGAAAAGGCTGGACTTGCGCAAGATGCTGTTACCGCAGAACGACGCCGTGTTTTGGGAACAGTTCGGAGAGCATGTCAAACAGTTGGACGCGTTAGAGAGGATAGAGATGTGCCGCTGCCCGGCCAGCGCGGTGGAGGCGGTGTGCCGCGGCGCGTCGCACCTGCGCGCGCTGTCCGCGCTCGCCATCCGCTCCGCGCTGTTCGACCCCGCGCCGCTCGGCGCCTTGTCGCAGCTGAGGGAGCTGCGGCTCAAGAGCATGGCGGGCTTGTCGCTCACGAGGGATTTACAACCGTTGGCGGCGCTGACGAGGCTCACGCATCTTTCGCTCACCTCCATCAAGGAACTAGGTTGGTGCGCGTGCGACGTAGTAGGACAACTCCCGCAACTCGAGTCGCTCGAGCTCGGCGAGTGCAGTTTTCGCGCCGAGTTCGCGCTCGTGCTGGGCAAGCTGACGCGCCTAAAGCGGCTGCGTCTAGAACGGGGCACCGCTCAATGTGCGGCCCCGGCTTTACTGCGAGCGGTGGCGCTACTGCCTAATCTTACTAGCTTGGAACTAGTCAATTTCGACGTCAAGGTCGGTTTTGACGACGCGCTGGCCGAATGCAAAAACATACAGAGGCTGCTTATCATACCCACGTACGTCTCGCAGTCCGCCACCACTAATAAACAGGTGCTAAGCGGCGTGCTGAGTCTCAAAGACACGCTAACCCATCTAATGTGGGGCGTCACCATCGAGCTGCTCCGCGTGACGGAGCTGTTCATCGACCAGTGCGAGCAGGGCGCCGAGCGTCGCCGCGACGTCGGCGAGTGCATCCCCGTGCTCAAGCCCGTCCCCGGCTGCAGGCTGCCCCCCGACAACGCCAAGCAGGAGCCCCGCACACCCCCGCAGGTATACAGTAGTGCATCCCCGTGCTCAAGCCCGTCCCCGGCTGCAGGCTGCCCCCCGACAACGCCAAGCAGGAGCCCCGCACACCCCCGCAGGCTGCCCCCCGACAACGCCAAGCAGGAGCCCCGCACACCCCCGCAGGTATACAGTAGTGCATCCCCGTGCTCAAGCCCGTCCCCGGCTGCAGGCTGCCCCCCGACAACGCCAAGCAGGAGCCCCGCACACCCCCGCAGGCTGCCCCCCGACAACGCCAAGCAGGAGCCCCGCACACCCCCGCAGGTATACAGTAGTGCATCCCCGTGCTCAAGCCCGTCCCGGGCTGCAGGCTGCCCCCCGACAACGCCAAGCAGGAGCCCCGCACACCCCCGCAGGTATACAGTAGTGCATCCCCGTGCTCAAGCCCGTCCCCGGCTGCAGGCTGCCCCCCGACAACGCCAAGCAGGAGCCCCGCACACCCCCGCAGGTATACAGTAG
Protein Sequence: MSDEMAVSDNPSGEEAVVNGPEALAASAEVAAPEAHDAPSAPADPEPEETKPIKLEPEWKSENAPEPAEDTDDKRGVKRRASAAFSNAAGEIFKPFKGFAKMELDDSIVDYKKVLDNLEAEVVETSKTVVPLRTVMGTPTAPARASKRARQDTDGSRPSSALSSRSEDGVSSTESLLVIRQVSSPLVRGRRATTEMSSPLLRVPLEKGWKRELVYRAALDQHSRRNADIYYYTPSNKKLRSTRETVYLSSPLLRVPLEKGWKRELVYRAALDQHSRRNADIYYYTPSNKKLRSTRETVYLSSPLLRVPLEKGWKRELVYRAALDQHSRRNADIYYYTPSNKKLRSTRETVYLSSPLLRVPLEKGWKRELVYRAALDQHSRRNADIYYYTPSNKKLRSTRETVYLSSPLLRVPLEKGWKRELVYRAALDQHSRRNADIYYYTPSNKKLRSTRETVYLSSPLLRVPLEKGWKRELVYRAALDQHSRRNADIYYYTPSNKKLRSTRERLGLFVPVWRPCPPGLSALPARRPARLFAGCPARTRRAANSPTARALELLNVLSIRAPQIDIFADSTVYLSSPLLRVPLEKGWKRELVYRAALDQHSRRNADIYYYTPSNKKLRSTREVAEHLSGTGLTLDNFSFFKEPLGVDDPEKEIIRDAKLMRKVESPVAQTAPPLAEGKRTPKPKPPKGASPDPVTPKSKSPLAKIKVKSMQPRLNRTPAAPSAKKPAASPASATATDNNNTQAIKKNRTAPPVPAVPVAPVPVPVAVPVPVPVMPVPVPVPVMPVPVPVPVPVPVAPAPPPLQSRPPVSPVDAKIEQHDLSSPRQLVQPCSMTCGRGVPTLACGLCLCLYHPACAGLTAPRPEGTFFCKNCRKSSSPSSSPPPLTHKSGLTSLVAPCARRPAPAPRPRPRPRPSTAAPSTAAAAQPADKRVTLRMKMAGGPGGARVWAVSPARGSLPQSLAVLNGRRFIVVPRAIVQPAPSDSKPVRGRVANGAAPSPTTDSPRRRGRPRLDENTDHFTAFCQKAKEHNYNVAKQIFQYLGMRDLAHCARVCRLWRELAATPQLWRHVRMKNSHVSDWGGLFAALRRHGTKRLDLRKMLLPQNDAVFWEQFGEHVKQLDALERIEMCRCPASAVEAVCRGASHLRALSALAIRSALFDPAPLGALSQLRELRLKSMAGLSLTRDLQPLAALTRLTHLSLTSIKELGWCACDVVGQLPQLESLELGECSFRAEFALVLGKLTRLKRLRLERGTAQCAAPALLRAVALLPNLTSLELVNFDVKVGFDDALAECKNIQRLLIIPTYVSQSATTNKQVLSGVLSLKDTLTHLMWGVTIELLRVTELFIDQCEQGAERRRDVGECIPVLKPVPGCRLPPDNAKQEPRTPPQVYSSASPCSSPSPAAGCPPTTPSRSPAHPRRLPPDNAKQEPRTPPQVYSSASPCSSPSPAAGCPPTTPSRSPAHPRRLPPDNAKQEPRTPPQVYSSASPCSSPSRAAGCPPTTPSRSPAHPRRYTVVHPRAQARPRLQAAPRQRQAGAPHTPAGIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -