Basic Information

Insect: Cydia pomonella
Gene Symbol: klhl22
Assembly: GCA_033807575.1
Location: CM066345.1:33831410-33843027[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.6e-20 1.7e-17 64.9 0.1 2 101 22 117 21 119 0.94

2 14 1.2e-07 5.7e-05 24.5 0.1 51 101 117 167 113 169 0.93

3 14 1.4e-07 6.3e-05 24.4 0.1 51 101 167 217 164 219 0.93

4 14 1.4e-07 6.3e-05 24.4 0.1 51 101 217 267 214 269 0.93

5 14 1.5e-07 6.9e-05 24.2 0.1 51 101 267 317 265 319 0.93

6 14 1.3e-07 5.8e-05 24.5 0.1 51 101 317 367 314 370 0.93

7 14 1.1e-07 5e-05 24.7 0.1 51 102 367 418 364 422 0.93

8 14 1.4e-07 6.3e-05 24.4 0.1 51 101 417 467 414 469 0.93

9 14 1.5e-07 6.9e-05 24.2 0.1 51 101 467 517 465 519 0.93

10 14 4.1e-07 0.00019 22.9 0.1 51 101 517 567 515 569 0.93

11 14 1.3e-07 5.8e-05 24.5 0.1 51 101 567 617 564 620 0.93

12 14 1.5e-07 6.9e-05 24.2 0.1 51 101 617 667 615 669 0.93

13 14 1.4e-07 6.3e-05 24.4 0.1 51 101 667 717 664 719 0.93

14 14 2e-07 9.1e-05 23.9 0.1 51 100 717 766 715 771 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.6e-20	1.7e-17	64.9	0.1	2	101	22	117	21	119	0.94
2	14	1.2e-07	5.7e-05	24.5	0.1	51	101	117	167	113	169	0.93
3	14	1.4e-07	6.3e-05	24.4	0.1	51	101	167	217	164	219	0.93
4	14	1.4e-07	6.3e-05	24.4	0.1	51	101	217	267	214	269	0.93
5	14	1.5e-07	6.9e-05	24.2	0.1	51	101	267	317	265	319	0.93
6	14	1.3e-07	5.8e-05	24.5	0.1	51	101	317	367	314	370	0.93
7	14	1.1e-07	5e-05	24.7	0.1	51	102	367	418	364	422	0.93
8	14	1.4e-07	6.3e-05	24.4	0.1	51	101	417	467	414	469	0.93
9	14	1.5e-07	6.9e-05	24.2	0.1	51	101	467	517	465	519	0.93
10	14	4.1e-07	0.00019	22.9	0.1	51	101	517	567	515	569	0.93
11	14	1.3e-07	5.8e-05	24.5	0.1	51	101	567	617	564	620	0.93
12	14	1.5e-07	6.9e-05	24.2	0.1	51	101	617	667	615	669	0.93
13	14	1.4e-07	6.3e-05	24.4	0.1	51	101	667	717	664	719	0.93
14	14	2e-07	9.1e-05	23.9	0.1	51	100	717	766	715	771	0.93

Sequence Information

Coding Sequence: ATGGCAGACTCGCAATTTTGTTTAGAGTGGGACTCCCACAACAAAAACATTTGTAATGGTTTAAGTTCCTTACAACAGaaTGGGGAGTTTGTGGACATGACGCTGGCGGCAGATGGCCACCATGTGAAGGTGCATCAGATGGTGATGGCGCTCGCCAGCCCGTACATTAAGGAGCTCATTTCCACTGCCAACTGTCCACATCCCGTTATCTTCTTAAATAAAGTATCATACAAGATACTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGTTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGTTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGTTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGTTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCACACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGTTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtggtaaatattacatttcagaAAGTATCATACAAGACGCTATGCTCAATACTGGAGTACATCTACACGGGACAGGCGTTGGTCGCCGTTGATGACATCAGTGAGCTGATCATCGCCGCCAAAGAGTTGCACATCAAGGGGCTGGAGGATGtgAAAGCAGTCAGTGAGACACCGTCAGTAACAGAAGTGGAAGTAGATTACGAAGTGCCAAAAGAGCTCCCAGAAATACAAATAAAGCTCCAACGACCTGACACATCCACCCCACAATTCTCAGCCTCGCTCCAGAACACTTTGAAGAGAAAACTCGAAAGCAATAAGACATTATCCAGCATGCCGATACGAAAAAGAGTTTTACTGAACAAATCGGAGACGGAAAACAGAGATATGCCCGTGTTACAGAAAGATGATGGAAAAGAAAAGGAGTTTGGTTATGATGACCCGTTGGATGTAGATGACCGGGATgattataatgatgatgatggagaTCAGGACACGACAGTGGCAGTTAGTAAGCCGTCAGCTGATAACCCTCAAATGTCCGTTCAATACACAGTATCCAACCAAGGCAGCCTGCAACTGATCCTGAACCGGTTCCTCTACTTCCTGTACTACCAGTACCGGGACAAGAGCCGACAGTGGCGCTGCGTGGACAACCGCAACAACAAGTGCATGGCCTCCGTCTTCACTAAGGACAACATTGTGCTCCGGAGAGTTGGTGCCCATAATCACACATTCCACGACAAGAACATACTAAAGAAAGTCCGCGCCGGTTCAGTGTATTCAGCCCTACAAGAAGCCGAGGCCAAAAGCACGCGCAACTGCCGAGGCCGCGGACAGAAACCGCGCAAATGTGATGCGGCAGAACAATCTGACAACCAGGATAACCAGGAAACGGACGTTACTCAATAA
Protein Sequence: MADSQFCLEWDSHNKNICNGLSSLQQNGEFVDMTLAADGHHVKVHQMVMALASPYIKELISTANCPHPVIFLNKVSYKILCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSHKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVVNITFQKVSYKTLCSILEYIYTGQALVAVDDISELIIAAKELHIKGLEDVKAVSETPSVTEVEVDYEVPKELPEIQIKLQRPDTSTPQFSASLQNTLKRKLESNKTLSSMPIRKRVLLNKSETENRDMPVLQKDDGKEKEFGYDDPLDVDDRDDYNDDDGDQDTTVAVSKPSADNPQMSVQYTVSNQGSLQLILNRFLYFLYYQYRDKSRQWRCVDNRNNKCMASVFTKDNIVLRRVGAHNHTFHDKNILKKVRAGSVYSALQEAEAKSTRNCRGRGQKPRKCDAAEQSDNQDNQETDVTQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -