Basic Information

Insect: Cydia amplana
Gene Symbol: zfh1
Assembly: GCA_948474715.1
Location: OX419679.1:5315486-5321310[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.6e-05 0.002 19.0 1.4 1 23 168 190 168 190 0.96

2 14 0.00026 0.014 16.3 0.9 1 23 196 218 196 218 0.98

3 14 1.4e-05 0.00077 20.2 2.9 1 23 224 247 224 247 0.97

4 14 0.0011 0.061 14.3 2.8 1 23 280 302 280 302 0.97

5 14 0.0003 0.016 16.1 1.7 1 23 308 330 308 330 0.92

6 14 1.2e-05 0.00063 20.5 2.5 1 23 336 358 336 358 0.98

7 14 1.1e-05 0.00061 20.6 2.5 1 23 364 386 364 386 0.98

8 14 0.00082 0.045 14.7 2.1 1 23 392 415 392 415 0.95

9 14 3.3e-05 0.0018 19.1 0.6 1 23 423 445 423 445 0.98

10 14 0.0039 0.21 12.6 1.2 1 23 474 496 474 496 0.97

11 14 9.2e-06 0.0005 20.8 1.9 2 23 503 524 502 524 0.97

12 14 1.8e-06 0.0001 23.0 2.4 1 23 529 552 529 552 0.97

13 14 7.3e-05 0.004 18.0 0.2 1 23 559 581 559 581 0.97

14 14 0.039 2.1 9.4 0.3 1 23 587 610 587 610 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.6e-05	0.002	19.0	1.4	1	23	168	190	168	190	0.96
2	14	0.00026	0.014	16.3	0.9	1	23	196	218	196	218	0.98
3	14	1.4e-05	0.00077	20.2	2.9	1	23	224	247	224	247	0.97
4	14	0.0011	0.061	14.3	2.8	1	23	280	302	280	302	0.97
5	14	0.0003	0.016	16.1	1.7	1	23	308	330	308	330	0.92
6	14	1.2e-05	0.00063	20.5	2.5	1	23	336	358	336	358	0.98
7	14	1.1e-05	0.00061	20.6	2.5	1	23	364	386	364	386	0.98
8	14	0.00082	0.045	14.7	2.1	1	23	392	415	392	415	0.95
9	14	3.3e-05	0.0018	19.1	0.6	1	23	423	445	423	445	0.98
10	14	0.0039	0.21	12.6	1.2	1	23	474	496	474	496	0.97
11	14	9.2e-06	0.0005	20.8	1.9	2	23	503	524	502	524	0.97
12	14	1.8e-06	0.0001	23.0	2.4	1	23	529	552	529	552	0.97
13	14	7.3e-05	0.004	18.0	0.2	1	23	559	581	559	581	0.97
14	14	0.039	2.1	9.4	0.3	1	23	587	610	587	610	0.95

Sequence Information

Coding Sequence: ATGGAAGCATATTACTCGTGTAGCTGCTGCCTGGTGCGCCCTCCGGACAAAGGCATCAAGACACTATACAATCATCTCGGCAAAGCAGAGATATATTACGACATGTTGAGAGAATGCTTTGGTTTAAATCTAAGTTTGGGAAATGACGAGTGCGGGATCTGCGAGGTGTGTGTGGGCCGGCTGCGGGACGCGAGCGACTTCAAGCTGCAAGTGCAGCGCGTGCAGGACGTACTGCACAAGCGGCTCACGGGAGCACTCCCTGCCAATGCTGGTGACAACATCAAAATCAAGTTAGAGACACCAGATGACGCCATTTCGCGCGGGATCAAGCAGGAGGGGCCGGAGGAGGAGGCTGACAGCAACTTTGTATCAGTTGCATTACACGAAGGATCGCCAGCGCCTTTTACTCAACCTGTTCCTACCGCGTCCCACAGCGCCTCGGTCGCGCCAGCCCCGAACACTACCAGGCGCCGGCGCCGCTCCAACACTGGAGAGAAACCTTACGCGTGCAACATATGCGACAAAAGATTCGGACAGAAGGGCCACTTTAATGTTCATTACGCAAACCATATAGGAAAATTCAAATTCTCTTGCGAATTATGCAAAAGGGGATTCGTATACAAACAACAATATATTACTCATATGCTGATCCATACTGGTGAAAAACCATACGAATGTGACATATGCAACAAGAAATATAGACATAAAGGCCAATTAAACCAACATAAAAATTCAATTCATTTTAAATATGATCAGGATCGCGTGGAGCCAGGAGAAATAACTACATGCAAAAAAGAGTCGTCAGAAGAATCAGAAGATCATGTGCTCGCTAAATATTTTACGTGTGATATATGCAGAAAGCAATTTGCGGATAAACACTATTTAGACGCTCATTCAAAATACCACTCTGGAGATTATCCGTTCACTTGCGACATTTGTAAAAGGAAATTTAATACGCAGTTTGCCTTGAATACACATAAAGTTGATCACTCGAGAGGGAGACCTTTTAAGTGTGATAAATGCAATAAAAGGTACACAACGAAAAGTGTTTTAACTCTACATTTGAAAGTTCACGCTGAGGATTATAAGTACGCATGTCATCTGTGTAGTAAACGATTCATAACAAGGGAGACATTTAATGTACACATGCGCGTACACACGGGGGAAAAGCCGTATACCTGTGTAACTTGTGAAGCTAAGTTCCGCTATAGATATGACTTGAAGAAACATTTATTGCAGAAACACAACCAAGTTATGGACAAACAGTTCAGTTGTGATACTTGTGGGAAACAATTTGCATTACAGGGGACGTTAGTAAAACATATGTACAGACACACTGTCCAGACTGAGAAGGCAACGAAGAAGATGGAAAAGAAGAAGAAGAAGAAGGAAACCGCTGATAAAAAGAAAGACCTAGCATTCATGTGTGAAATATGTAGCAAACGATTTTCGACAATAGCTATTCTAAAAACCCATAGATTCACACATAATGAAGAAAAACCTATCGAGTGCGATGTATGTCATAAAAAATACCGAACGAAGAGGAATTTACTGGACCACATGCAGGTGCACGAGGAAAAAAAACACTCGTGTGAAGTATGCGGCCAGCCATTCAGACATAAGTCTGCCTTGAATGTTCATATCCGACGGTTCCACTCCGAAAACAGTAGACCACATGTTTGCGATATTTGTAATAAGGCTTTTGTGGTTCTTGCTCAACTTAAAGAACATTCTCGGGTACACACTGGGGAGAAACCGTATGCTTGCGAAATATGCTATAAGAAATTTCCGTGGCAAAACGGGGTTAAACGACATCTTAAACAAGTTCACAACGAGAAACCTACGAGATTTGTTAAAATAACAGAATTGAATAAATATGACTAA
Protein Sequence: MEAYYSCSCCLVRPPDKGIKTLYNHLGKAEIYYDMLRECFGLNLSLGNDECGICEVCVGRLRDASDFKLQVQRVQDVLHKRLTGALPANAGDNIKIKLETPDDAISRGIKQEGPEEEADSNFVSVALHEGSPAPFTQPVPTASHSASVAPAPNTTRRRRRSNTGEKPYACNICDKRFGQKGHFNVHYANHIGKFKFSCELCKRGFVYKQQYITHMLIHTGEKPYECDICNKKYRHKGQLNQHKNSIHFKYDQDRVEPGEITTCKKESSEESEDHVLAKYFTCDICRKQFADKHYLDAHSKYHSGDYPFTCDICKRKFNTQFALNTHKVDHSRGRPFKCDKCNKRYTTKSVLTLHLKVHAEDYKYACHLCSKRFITRETFNVHMRVHTGEKPYTCVTCEAKFRYRYDLKKHLLQKHNQVMDKQFSCDTCGKQFALQGTLVKHMYRHTVQTEKATKKMEKKKKKKETADKKKDLAFMCEICSKRFSTIAILKTHRFTHNEEKPIECDVCHKKYRTKRNLLDHMQVHEEKKHSCEVCGQPFRHKSALNVHIRRFHSENSRPHVCDICNKAFVVLAQLKEHSRVHTGEKPYACEICYKKFPWQNGVKRHLKQVHNEKPTRFVKITELNKYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00410540;
90% Identity: iTF_00409935;
80% Identity: iTF_00409935;