Basic Information

Insect: Cyclargus thomasi
Gene Symbol: tfap2e
Assembly: GCA_026546445.1
Location: JAOTAV010018313.1:3918-19450[-]

Transcription Factor Domain

TF Family: AP-2
Domain: TF_AP-2 domain
PFAM: PF03299
TF Group: Basic Domians group
Description: Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.7e-81 3.8e-77 258.9 0.0 1 196 189 381 189 382 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.7e-81	3.8e-77	258.9	0.0	1	196	189	381	189	382	0.97

Sequence Information

Coding Sequence: ATGGCTATTTACCTCGATCAAATATACTATTATTTGATCGAGGAGCGCCTCGGCGGTGGCGGGCTCGGGCTGGGCGGCGGCGGGTTCCGCGGCGGTGCGCAGCCATCGCTCGCGGACTTCCAGCCGCCCTACTTCCCCCCGCCCTTCGCGCCCGCCGCGCACCCCGCCAGCCCGCATCATCAGCAGCAGAGCCATGGCATGGAATACAACGGCGGCGGCGGCGGCGAGTATGCACAGCACTACGCGCCGCAGCAGCTGCTGCCGCGACACCACACGCACCACGAGCCCCACCCTCACCTCCGACATAGGGACAGCCATGACGTCATACACTCGCACCACCTATCACACGGCGGATTCAGCTACGGTGGTGCGGAGAGGCGGGCGGATTACGGCGCGCGGGACCAACACGAACTCGCCCTACACCATGCACTGCACTCCGCTGACGAGACACAAAATGCAGGCATGGATGATACAAGCGGGTTCATGACAGATCTACCTCTATTAAAAACAATGAAAGGCCGTGACGGTCTGGGCGGCGGCGGGTCTTGCGCGCCCAACGACGTGTTCTGCTCGGTGCCGGGCAGGTTGTCGCTGCTGTCCTCCACCAGCAAGTACAAGGTTACCGTTGCCGAGGTGCAGCGCCGGTTGTCGCCGCCGGAGTGCTTGAACGCCTCGCTACTCGGAGGAGTGTTGAGGAGGGCGAAAAGCAAAAATGGCGGGCGGTTACTCCGGGAGAAGTTAGAGAAGATCGGTCTCAACCTGCCCGCTGGTCGGCGGAAAGCCGCCAACGTTACGCTGCTCACCTCACTAGTTGAAGCGGAGGCGGTGCACCTGGCGCGCGACTTCGGCTACGTGTGTGAGACGGAGTTCCCGGCGCGCGCGCTGGCCGAGTACCTCGCGCGGCAGTACGCCGAGCACGACGCACGACGACGACGAGACCTGCTGCAGGCCACCAAACAGGTGATCAAGGAGCTGATGGACCTGCTGAACCAGGACCGGTCGCCGCTCTGCAACACGCGGCCACCTCACCTGCTGGAGCCCGCCATACAGCGCCACCTCACGCACTTCTCGCTCATCTCGCACGGCTTCGGCGGTCCCGCCATCGTCGCCGCTCTGACCGCCATACAGAATTTCCTCAACGAGTCGCTGAAGCACCTAGATAAGCTTTATCCTCAGAGCGGTATGGTCTCCTCCTCGATGGACAAGACCAAGATGGACCCCGACATCAAGAAGTAA
Protein Sequence: MAIYLDQIYYYLIEERLGGGGLGLGGGGFRGGAQPSLADFQPPYFPPPFAPAAHPASPHHQQQSHGMEYNGGGGGEYAQHYAPQQLLPRHHTHHEPHPHLRHRDSHDVIHSHHLSHGGFSYGGAERRADYGARDQHELALHHALHSADETQNAGMDDTSGFMTDLPLLKTMKGRDGLGGGGSCAPNDVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEAEAVHLARDFGYVCETEFPARALAEYLARQYAEHDARRRRDLLQATKQVIKELMDLLNQDRSPLCNTRPPHLLEPAIQRHLTHFSLISHGFGGPAIVAALTAIQNFLNESLKHLDKLYPQSGMVSSSMDKTKMDPDIKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01217155; iTF_00934420; iTF_01247739; iTF_00744286; iTF_00021025; iTF_00341898; iTF_01134462; iTF_00149057; iTF_00772564; iTF_00177761; iTF_01500780; iTF_00274928; iTF_00077171; iTF_00827671; iTF_00250145; iTF_00761313; iTF_00818049; iTF_00960609; iTF_00011618; iTF_00075138; iTF_00909442; iTF_01019906; iTF_01435746; iTF_00185825; iTF_00427777; iTF_00783105; iTF_00793953; iTF_00007682; iTF_01026978; iTF_00908483; iTF_01377155; iTF_00930917; iTF_00467878; iTF_00677222; iTF_00822566; iTF_00925415; iTF_01332231; iTF_00711496; iTF_00736297; iTF_01416457; iTF_01501770; iTF_00042315; iTF_01285227; iTF_01358571; iTF_00851372; iTF_00932108; iTF_00171437; iTF_00809741; iTF_00156878; iTF_00280814; iTF_00673998; iTF_00818831; iTF_00072401; iTF_00122033; iTF_00635953; iTF_01251442; iTF_00467155; iTF_00951475; iTF_01073267; iTF_01179187; iTF_01197395; iTF_00123028; iTF_00786454; iTF_00821462; iTF_01166263; iTF_01093720; iTF_01264088; iTF_00256537; iTF_00928345; iTF_01360281; iTF_00673179; iTF_00040476; iTF_00869308; iTF_00425055; iTF_00823615; iTF_01491551; iTF_00639968; iTF_01440672; iTF_00363713; iTF_00622497; iTF_00237154; iTF_00017860; iTF_00287748; iTF_00374852; iTF_00887876; iTF_01532709; iTF_01083921; iTF_00301781; iTF_01061565; iTF_00687590; iTF_00261526; iTF_00715494; iTF_00771558; iTF_01118918; iTF_01063431; iTF_00038376; iTF_00036306; iTF_00146984; iTF_00907560; iTF_01525608; iTF_00123913; iTF_00299828; iTF_00973404; iTF_00208489; iTF_00207524; iTF_01062441; iTF_01339625; iTF_00049578; iTF_00071114; iTF_01526698; iTF_00719883; iTF_00120173; iTF_01341901; iTF_01117933; iTF_01534477; iTF_00784078; iTF_01359406; iTF_00212111; iTF_00774948; iTF_00213097; iTF_00273295; iTF_01025647; iTF_00725968; iTF_00274129; iTF_00326769; iTF_00357105; iTF_00358206; iTF_00808785; iTF_01172945; iTF_00787307; iTF_00858224; iTF_00063264; iTF_01246513; iTF_00924274; iTF_01084818; iTF_01338163; iTF_00784884; iTF_00906740; iTF_00176789; iTF_01192309; iTF_01259765; iTF_00037462; iTF_00041462; iTF_01018262; iTF_00111256; iTF_00121080; iTF_01439576; iTF_01221177; iTF_00685114; iTF_00850266; iTF_01027930; iTF_01533626; iTF_00159515; iTF_00722721; iTF_00984707; iTF_01020868; iTF_00954087; iTF_00779209; iTF_00695147; iTF_00247725; iTF_00620909; iTF_00642029; iTF_00779953; iTF_00246867; iTF_00774196; iTF_00782324; iTF_00780725; iTF_01181593; iTF_00456926; iTF_00457696; iTF_01150912; iTF_00345499; iTF_01064315; iTF_00184988; iTF_00448701; iTF_00745309; iTF_00757822; iTF_01094590; iTF_01538430; iTF_00445791; iTF_01531647; iTF_00043168; iTF_00172416; iTF_00638339; iTF_00686019; iTF_00737155; iTF_00994052; iTF_01090372; iTF_01178084; iTF_00681349; iTF_00006765; iTF_00708838; iTF_00896458; iTF_00000001; iTF_00874145; iTF_00000866; iTF_00875842; iTF_00874995; iTF_00826502; iTF_00323143; iTF_00411079; iTF_00699783; iTF_00789927; iTF_01082983; iTF_01386407; iTF_01388151; iTF_00412200; iTF_01149256; iTF_00055081; iTF_00680201; iTF_00913289; iTF_00032586; iTF_00163978; iTF_00235562; iTF_01489829; iTF_01116842; iTF_00777694; iTF_01222154; iTF_00957643; iTF_00146091; iTF_00012620; iTF_00421036; iTF_01171148; iTF_01543532; iTF_01017421; iTF_00255501; iTF_01140621; iTF_01202157; iTF_01206211; iTF_01205382; iTF_01203725; iTF_01202931; iTF_00878553; iTF_01509261; iTF_00666190; iTF_01170254; iTF_01172014; iTF_01182350; iTF_00659151; iTF_01157359; iTF_01153545; iTF_00194864; iTF_00432816; iTF_00659984; iTF_01245616; iTF_01367376; iTF_01545443; iTF_01544552; iTF_01041417; iTF_01546298; iTF_01141328; iTF_01144242; iTF_01280983; iTF_00074165; iTF_01279864; iTF_01402423; iTF_00204062; iTF_01560816; iTF_01568939; iTF_00205742; iTF_00428687; iTF_01281904; iTF_01278952; iTF_00361297; iTF_01415505; iTF_00364595; iTF_01527955; iTF_00027444; iTF_00026519; iTF_00801492; iTF_00843189; iTF_00796165; iTF_00824390; iTF_01077862; iTF_01507750; iTF_00985673; iTF_01080395; iTF_01506029; iTF_01079541; iTF_01078749; iTF_00114614; iTF_00142774; iTF_00701654; iTF_00697953; iTF_00705667; iTF_00700682; iTF_00702571; iTF_01311927; iTF_00795382; iTF_01437646; iTF_01438576; iTF_00895606; iTF_00155927; iTF_00154993; iTF_00325049; iTF_00856279; iTF_01400951; iTF_00022488; iTF_00403384; iTF_00009689; iTF_00810681; iTF_01076057; iTF_00959098; iTF_01133402; iTF_01436698; iTF_00249403; iTF_01494753; iTF_01495468; iTF_01115406; iTF_01493998; iTF_00648795; iTF_01424731; iTF_01443516; iTF_00819741; iTF_01503517; iTF_00390046; iTF_00683006; iTF_00034397; iTF_00318593; iTF_00751713; iTF_01081223; iTF_00278796; iTF_00284207; iTF_00005973; iTF_00035321; iTF_00790878; iTF_00926270; iTF_00653919; iTF_01428735; iTF_01335616; iTF_01219467; iTF_00662772; iTF_01547200;
90% Identity: iTF_00925415;
80% Identity: -