Basic Information

Insect: Cyaniris semiargus
Gene Symbol: ZFX
Assembly: GCA_905187585.1
Location: LR994550.1:610565-615614[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 8.5e-05 0.0064 17.3 1.2 1 23 249 271 249 271 0.98

2 27 1.3 1e+02 4.1 0.6 6 23 283 300 283 300 0.96

3 27 1.2 87 4.3 1.5 1 23 309 332 309 332 0.90

4 27 0.0001 0.0077 17.1 3.2 3 23 353 373 352 373 0.98

5 27 0.00016 0.012 16.5 0.7 1 23 379 402 379 402 0.96

6 27 0.58 44 5.3 0.0 1 23 408 430 408 430 0.93

7 27 0.0003 0.023 15.6 0.1 1 23 436 458 436 458 0.96

8 27 0.46 35 5.6 1.4 1 23 578 600 578 600 0.95

9 27 3.3e-05 0.0025 18.6 2.2 2 23 607 629 606 629 0.92

10 27 6.2e-05 0.0047 17.8 1.7 1 23 635 657 635 657 0.96

11 27 1e-05 0.00076 20.3 0.6 1 23 663 685 663 685 0.97

12 27 0.0023 0.17 12.9 0.1 1 23 691 713 691 713 0.98

13 27 0.013 1 10.4 2.5 1 23 719 741 719 741 0.95

14 27 0.31 24 6.1 6.0 1 23 747 770 747 770 0.92

15 27 0.38 28 5.9 0.2 2 23 831 851 830 851 0.96

16 27 0.00022 0.017 16.0 0.3 1 23 857 880 857 880 0.89

17 27 8.3e-05 0.0063 17.4 1.7 1 23 886 908 886 908 0.94

18 27 0.0006 0.046 14.7 0.3 1 23 914 936 914 936 0.97

19 27 0.00063 0.048 14.6 1.0 1 23 942 964 942 964 0.96

20 27 0.00067 0.051 14.5 0.3 6 23 974 991 973 991 0.99

21 27 2.8 2.1e+02 3.1 0.5 1 23 1057 1078 1057 1078 0.86

22 27 0.011 0.83 10.7 0.6 3 23 1189 1210 1188 1210 0.96

23 27 0.0018 0.13 13.2 0.1 1 23 1216 1238 1216 1238 0.97

24 27 0.00034 0.025 15.5 0.1 1 23 1244 1266 1244 1266 0.97

25 27 0.00019 0.015 16.2 3.1 1 23 1272 1294 1272 1294 0.96

26 27 0.00013 0.0097 16.8 0.2 1 23 1300 1322 1300 1322 0.96

27 27 0.00041 0.031 15.2 0.4 2 23 1328 1350 1327 1350 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	8.5e-05	0.0064	17.3	1.2	1	23	249	271	249	271	0.98
2	27	1.3	1e+02	4.1	0.6	6	23	283	300	283	300	0.96
3	27	1.2	87	4.3	1.5	1	23	309	332	309	332	0.90
4	27	0.0001	0.0077	17.1	3.2	3	23	353	373	352	373	0.98
5	27	0.00016	0.012	16.5	0.7	1	23	379	402	379	402	0.96
6	27	0.58	44	5.3	0.0	1	23	408	430	408	430	0.93
7	27	0.0003	0.023	15.6	0.1	1	23	436	458	436	458	0.96
8	27	0.46	35	5.6	1.4	1	23	578	600	578	600	0.95
9	27	3.3e-05	0.0025	18.6	2.2	2	23	607	629	606	629	0.92
10	27	6.2e-05	0.0047	17.8	1.7	1	23	635	657	635	657	0.96
11	27	1e-05	0.00076	20.3	0.6	1	23	663	685	663	685	0.97
12	27	0.0023	0.17	12.9	0.1	1	23	691	713	691	713	0.98
13	27	0.013	1	10.4	2.5	1	23	719	741	719	741	0.95
14	27	0.31	24	6.1	6.0	1	23	747	770	747	770	0.92
15	27	0.38	28	5.9	0.2	2	23	831	851	830	851	0.96
16	27	0.00022	0.017	16.0	0.3	1	23	857	880	857	880	0.89
17	27	8.3e-05	0.0063	17.4	1.7	1	23	886	908	886	908	0.94
18	27	0.0006	0.046	14.7	0.3	1	23	914	936	914	936	0.97
19	27	0.00063	0.048	14.6	1.0	1	23	942	964	942	964	0.96
20	27	0.00067	0.051	14.5	0.3	6	23	974	991	973	991	0.99
21	27	2.8	2.1e+02	3.1	0.5	1	23	1057	1078	1057	1078	0.86
22	27	0.011	0.83	10.7	0.6	3	23	1189	1210	1188	1210	0.96
23	27	0.0018	0.13	13.2	0.1	1	23	1216	1238	1216	1238	0.97
24	27	0.00034	0.025	15.5	0.1	1	23	1244	1266	1244	1266	0.97
25	27	0.00019	0.015	16.2	3.1	1	23	1272	1294	1272	1294	0.96
26	27	0.00013	0.0097	16.8	0.2	1	23	1300	1322	1300	1322	0.96
27	27	0.00041	0.031	15.2	0.4	2	23	1328	1350	1327	1350	0.95

Sequence Information

Coding Sequence: ATGAATATTGAGAGTGAAAAAATGCTTGTAAATTCAAGTGCAAATTTGTCGCAAGAGAGCCAAAGTTTCGAGGAAACCTGCAATGTGTTGAATGGTCTAGAAAATTTAACAAATGTCTGCCGAACATGTGCAAATGTAACAGAGTTTGTTATACCCATATTCGTCGGTGAGGGTCTACACAATAACTTGCCACAAAAAATTCAGCAACATCTTCCAATAAAGATATCAGAGGATGATGTTCTGCCGCATGTGGTGTGCTACCAGTGCGCCAGCACTATCCTCGCCTGGCATGACCTCGTGGAGTGTTGCCTCCAGGCTGACGTGACACTGCAGCAGCGAATATCTTCACTTACTAATGAAACAGAGCTGAAAATAAATTCAAACCAAAGATTAGAGGATAATGAAGATAGTTCTGCCAAAAAAGGGGACGATAAACTTTTAAGCCTAGTATATGACATAATTCGTGAGTACCTACAACTTATGGAATTAGATGAAAATAATATTATGGATTTAGATTACGTGTGCCAGGTCTGTGCTCACAAACCTGCAGCAAAAACAATAGACAACTTGGTTAAACACCTCCAGTTATCTCATAGCACGGAACTCTGCAACTCGGAGTCTATACAGAACTTCATTAGGAACAATATAACTTTTGAAGAATCTTTAAGCACGGAAGACCAAGATGACCATTGGAGTGATACAGACAAAGGAATCAATAAAGAGGCCGGCACCGACTTGCCAGCATACTTCTGCCCCTACTGCGACAGCGCCTTCTCCACACCTACTAGGCTGATACATCACATCAACAGACACATAGATATATCGACAGAGAGTGTGCTAACATGCTGCGGGGAAAGCTTCAACAAAAAATCCTTTGCGCTCCACCTGCAGCGCAGGCACGTGGCGCGCGTCGTCGCGGGCCCGCATGTGTGCCGGAGCTGCTCCCACAGCGCGCGCACCGAGCACGACCTGCAAGCGCACGTGGCCGCCGAGCACCGCGCGCAGCCCGCCGCCCGCCCCGAGCCGCGCCGTCGCCGCTCGCACGCGCCCGCCATCTGCCCCCGGTGCCGCAAGACTTTCTCCAACAAACACAACATGCTGGTGCATCTGAGGTCGCACAACGCAAGCGAGCCGTTCGCGTGCGACAGATGCGACAGGCGCTACAGGACCCGGAGCGGCCTGAGCGAGCACCGCCGGATCGTCCACGAGGGCGTGATGCGGCACGTGTGCGCAGCGTGCGGCGAGGCCTTCCCCACGCGCGGCGCGCGCGACGTGCACGCCCGCCTGCACTCCGGCGCGCGCCCCTACGCCTGCGACTACTGCGGCAAGGCCTACCGCGCCAAGAACACGCTGGACCGCCACATCGAAGCGCACTTGGACGTCCGGAAGTGCGCGCCCCGCCCCGGCCTCGCAGCGGCGCCGAGCGAGACGGCCGGGGAGCGCGTCGATCACGACGACGACGACGAGCCCCTGGCGAGCGTGGCGGGGAGAAAGGCCGCCGAGCTGTACGGAAACTTCTACGGCGCCCTCGTAAATTTTCGGGACCATCTCGCTACCGAGCACGAGGGGAGCTCCCCGGACTCCGGTGACTCCGACGGGGGCGGGAGCGACGAGGCAGTCGGCGACGACTACGACGACCTCACTCGAGGCGGCGCGAGAAGGGGGGGGCCGAGCGCCGAGACGGACCTCGAGCTCGCCCGCGCGCAGACGAGGGTCGACGGGCGGGCGTACTACGCGTGCGGGACGTGCGGCAAGCACCTCAGCTCAGCGCAGACCTACCTGTTCCACCGGCGCATCCACACGGACGAACGGCCATGCGTGTGCCACGTCTGCGGCAAGCAGTTCCGCACGCCCAACGGCCTGCGCCGCCACCTCGCCGAGACCCACGAGCGCCGCCGGTTCCACGCCTGCGCGCTGTGCCACAGGACCTTCGCCAACTCCCAGAACCTCCGGGCGCACGCGCGCATCCACACCGGCGAGAAGCCGTTCGTGTGCGCGCAGTGCGGGAAGCGCTTCACGCAGAGCGGCTCCCTGCACGCGCACGCGCGCGGCCACAGCGCGCTGCACCCGTACCGCTGCGCCGAGTGCGGAGCGCAGTTCAAGCTGCGCGCCGGCCTCGCGCGCCACGCGCTGCGGCACACGGGCGAGCGGCCGCACGCATGCGACGCGTGCGCGCGCGCTTTCCGCCACCGCCACGAGCTCACCGCGCACGCGCTCACGCACACCGACGCCCGCCCGCACGCCTGTCGCCTCTGCGGCTCCGCCTTCCGCCAGCGCAAGGCGCTGCGCCACCACTGCAGACGCGTCCACGAGACCGATGCCGCGGACGCGCCCGGCCCGGTGGTCTACGACCACGTCGGCCCGTTCGATGCGAACGTAAAAGACGAGATCGGGGACGACGAGAGTCGATCGACCGCCCCCGAGCAGCGAAAGCCGGCCGACGAGTCGAGGAAGCCGACTACGCTCTGGAGCGACGGAAAAGAATACGTGGAGTGCACTCTGTGCAACAAAAACGTCCCGGCCGCGTCCTGGCGCCGCCACCGGCGGTCCCACCAGGGCGGGCGGCCGCACAGCTGCCACGTGTGCGGGCTGGGGTTCGCCGACCGCGGCAACCTCGCGCGCCACGCGGCGGAGCGCCACCGCCGCCTGCGCCCGCACGCCTGCGCCCTCTGCGACCGGACGTTCGCGCGCAAGTCGCACCTGCGGGACCACGCGGCGTCGCACTCGACCGCGCGCGACCACGTGTGCGACGTGTGTGGCCGCGCCTCCAAGTCCGCCGCCGCGCTGCGCATGCACAAGAAGATGCACGATGACACGCTCGGGTTTCACTGCGCGTTCTGCGACGCTCGATTCAGGAGGAGGAGCCAGCTCGTGGCTCACGCGTCCGTGCACACCGGGGAGAGGGCCCACGCGTGCGCCTGCGGCCGGACTTTCCGTCTGCGCAGCCAGCTCAACGCGCACGCCCGCACGCACGACGACGGGCGACCGCGGGGAGACGAAACGGGCCCCGATCCGCGGGACGATGTCGCGAGGCCGATCGACCGGCCCGACCCCGCCGAGTCGGCGGCCCCCCCTCCGGTGCCCCCGCGGACCTGCACCTACTGCCGGGCGGAATGCCCCGAGCCCCAGCTCAAGGAGCACCTGATATCGACGCACTCGGAGCTGCTGTTCCGCTGCGACGAGTGCGACAGCTACGTCGACCGCCAGGACTTCGTCGAGCATATGTCGCAGCACGCCGTCGAGTACGCCGCCGACGCCGCGGGGGAGACTCGCCCCGAGGAGGCCCGCCCCACGCCCGACGTGCCCGGGGACCCCGGGGGACGTGGGGGCGACCGCACGGGAGACGGGGGCGCCTCGGAGAACGGGGACGACTTCTCGGACCACAGCGACGCGGAGTACTTCGGCGAGCTGCCCGACTCCGTGTTCGAGGCCATCGAGGACTCGCAGGACACGCAAGCGGCCGACGACGGCGACCGCCTCTCGCGGACCGACGCCGCGACCCCCGCCGTCTCCGCAGCGCCGCTCCCCCCCGTCGACGGGAGGAAAACGAAAAAGGAGCGGGCGTGCCCCGTCTGCTCGAAGGTGTACACCGCCAGCTCCAGCTACTTCTACCACCTGAAGCACGCGCACGGCGCCGACCGGCAGCACGAGTGCGACGTCTGCGGGAGGAGGTTCGGCGCCAAGCCGACGCTGGCGCAGCACCTGCTCATCCACGCGGCGGAGCGGCCGTACGCGTGCGCGCAGTGCGGCAAGACGTTCCGCGCGCGCGCCGCTCTCTACGTGCACGAGCAGACGCACGGCGGGCGCAGGACGCACGCGTGCGGGGAGTGCGGGCGCTCGTTCCGCTGGCGCGCGCACCTCGAGCGGCACCGGCGGCGGCACGAGAACGGGCGCGAGCACGCGTGCGACGCCTGCGGGCGGGCCTTCAGCGTGCGCGCCGACCTGCTGCGGCACGCGCGCACGCACGCAGCCGCGGCGCTGCCGTGCCCGCACTGCGAGCTGCAGTTCGCGCAGCCCCGCTACTTGCGCGCGCACCTCAACAACAAGCACGCCGCCGAGCTCGGAGGAGTCGTGAAATGA
Protein Sequence: MNIESEKMLVNSSANLSQESQSFEETCNVLNGLENLTNVCRTCANVTEFVIPIFVGEGLHNNLPQKIQQHLPIKISEDDVLPHVVCYQCASTILAWHDLVECCLQADVTLQQRISSLTNETELKINSNQRLEDNEDSSAKKGDDKLLSLVYDIIREYLQLMELDENNIMDLDYVCQVCAHKPAAKTIDNLVKHLQLSHSTELCNSESIQNFIRNNITFEESLSTEDQDDHWSDTDKGINKEAGTDLPAYFCPYCDSAFSTPTRLIHHINRHIDISTESVLTCCGESFNKKSFALHLQRRHVARVVAGPHVCRSCSHSARTEHDLQAHVAAEHRAQPAARPEPRRRRSHAPAICPRCRKTFSNKHNMLVHLRSHNASEPFACDRCDRRYRTRSGLSEHRRIVHEGVMRHVCAACGEAFPTRGARDVHARLHSGARPYACDYCGKAYRAKNTLDRHIEAHLDVRKCAPRPGLAAAPSETAGERVDHDDDDEPLASVAGRKAAELYGNFYGALVNFRDHLATEHEGSSPDSGDSDGGGSDEAVGDDYDDLTRGGARRGGPSAETDLELARAQTRVDGRAYYACGTCGKHLSSAQTYLFHRRIHTDERPCVCHVCGKQFRTPNGLRRHLAETHERRRFHACALCHRTFANSQNLRAHARIHTGEKPFVCAQCGKRFTQSGSLHAHARGHSALHPYRCAECGAQFKLRAGLARHALRHTGERPHACDACARAFRHRHELTAHALTHTDARPHACRLCGSAFRQRKALRHHCRRVHETDAADAPGPVVYDHVGPFDANVKDEIGDDESRSTAPEQRKPADESRKPTTLWSDGKEYVECTLCNKNVPAASWRRHRRSHQGGRPHSCHVCGLGFADRGNLARHAAERHRRLRPHACALCDRTFARKSHLRDHAASHSTARDHVCDVCGRASKSAAALRMHKKMHDDTLGFHCAFCDARFRRRSQLVAHASVHTGERAHACACGRTFRLRSQLNAHARTHDDGRPRGDETGPDPRDDVARPIDRPDPAESAAPPPVPPRTCTYCRAECPEPQLKEHLISTHSELLFRCDECDSYVDRQDFVEHMSQHAVEYAADAAGETRPEEARPTPDVPGDPGGRGGDRTGDGGASENGDDFSDHSDAEYFGELPDSVFEAIEDSQDTQAADDGDRLSRTDAATPAVSAAPLPPVDGRKTKKERACPVCSKVYTASSSYFYHLKHAHGADRQHECDVCGRRFGAKPTLAQHLLIHAAERPYACAQCGKTFRARAALYVHEQTHGGRRTHACGECGRSFRWRAHLERHRRRHENGREHACDACGRAFSVRADLLRHARTHAAAALPCPHCELQFAQPRYLRAHLNNKHAAELGGVVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01217675;
90% Identity: iTF_00935010;
80% Identity: -