Cbre008594.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- Aef1
- Assembly
- GCA_036172545.2
- Location
- CM070086.1:30672328-30673422[-]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.00062 3.2 7.7 0.0 21 49 15 43 11 46 0.86 2 4 0.0002 1 9.3 0.0 21 51 43 73 41 74 0.87 3 4 0.0024 12 5.9 0.0 21 49 71 99 69 102 0.86 4 4 0.00023 1.2 9.1 0.1 21 46 99 124 96 129 0.90
Sequence Information
- Coding Sequence
- ATGTCTAGGGTAACGAAAGATATGAAATTGCCAATGACAAGTACTGAAAAGCCGTTTATCTGTCCGACGTGCGACAAACAATTCAAACAGCTGAGCACCCTTACCAATCACATGAAAATCCATACAGGTGAAAAACCCTTCAAATGTACCTTCTGCTCGAAGGAGTTTCGGCAGTCGAGCACACTCAcgaatcacataaaaattcatactGgTGAAAAGCCATTTTCCTGTACATTTTGCTCAAAACAGTTTCGACAACTTAGCACTTTGTCGAATCATGTTAAAATTCACACAGGCGAAAAACCGTTCGAATGCAGCTTTTGTCAGAAGCAATTTCGACAATCGAGCACATTGAACAACCACATCAAAGTCCACGCCAGCGAAAAATTCGATTCGGGTATAAACAGTGTCGTGACACAATGTCTGGACGACGTGGCTGCACTGAAAGTTGAGGCTGAGTAtacgaattaa
- Protein Sequence
- MSRVTKDMKLPMTSTEKPFICPTCDKQFKQLSTLTNHMKIHTGEKPFKCTFCSKEFRQSSTLTNHIKIHTGEKPFSCTFCSKQFRQLSTLSNHVKIHTGEKPFECSFCQKQFRQSSTLNNHIKVHASEKFDSGINSVVTQCLDDVAALKVEAEYTN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00403101;
- 90% Identity
- iTF_00403101;
- 80% Identity
- iTF_00403101;