Basic Information

Insect: Culicoides brevitarsis
Gene Symbol: -
Assembly: GCA_036172545.2
Location: CM070087.1:23569048-23571826[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.5 96 3.5 0.4 3 11 335 343 334 346 0.87

2 10 0.035 1.3 9.4 3.2 1 23 372 395 372 395 0.98

3 10 1 39 4.8 0.7 1 23 402 425 402 425 0.94

4 10 0.00037 0.014 15.6 0.4 2 23 433 455 432 455 0.92

5 10 3.7 1.4e+02 3.0 0.8 2 21 460 479 460 480 0.93

6 10 0.033 1.2 9.5 0.3 1 23 485 508 485 508 0.97

7 10 0.076 2.9 8.3 1.9 3 23 514 535 513 535 0.95

8 10 2.5e-05 0.00097 19.3 0.5 3 23 542 563 541 563 0.96

9 10 0.0015 0.056 13.7 3.2 1 23 602 624 602 624 0.95

10 10 0.00012 0.0045 17.2 1.2 1 23 630 653 630 653 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.5	96	3.5	0.4	3	11	335	343	334	346	0.87
2	10	0.035	1.3	9.4	3.2	1	23	372	395	372	395	0.98
3	10	1	39	4.8	0.7	1	23	402	425	402	425	0.94
4	10	0.00037	0.014	15.6	0.4	2	23	433	455	432	455	0.92
5	10	3.7	1.4e+02	3.0	0.8	2	21	460	479	460	480	0.93
6	10	0.033	1.2	9.5	0.3	1	23	485	508	485	508	0.97
7	10	0.076	2.9	8.3	1.9	3	23	514	535	513	535	0.95
8	10	2.5e-05	0.00097	19.3	0.5	3	23	542	563	541	563	0.96
9	10	0.0015	0.056	13.7	3.2	1	23	602	624	602	624	0.95
10	10	0.00012	0.0045	17.2	1.2	1	23	630	653	630	653	0.97

Sequence Information

Coding Sequence: ATGATACGAGACTTGAAGAACGCCGGACTTCAAATCGACTTCATGACAGCAGAAGATTACGTCAGTATTCGTCGTAGTGGGCACCATGAGCGGCATTTCgtaattttgaaggaaatgcAAGAGGAGGACGTTGATAACATTTTTCGTGTCGCAATTTCCATTTCCGGGAACAAACCGCTACCATCTCAAATGTTCAAAAAGATGGAATGTGGATTAATATGcaaaatggTTCGAAACTACAAACCAAAAACCGACAGACCCAAAATAAGTGAAGCCGACATCGCTGCTGCAGTCGAGGATGTGATTAAACATCAAATTTCCGTCCATCAAGCGGCTctgaaacataaaattaatcaacaaaCTCTCTATAGCCGCATCAGAAAGTTGCGTTCTGAAATCTCTTTGGATGGTTCTTCTCTTGAAAACATAGAAAACGTTCTTAATGATCCTAATATTTCAACAATTGTTACTCAAAAgactgctaaaaaaattttcacggaccaacaagaagaagaacttGCAAAATTCATTCTGGATCGTCCGGATCCGAATATCACAAGAACCCAATGTCGCGAAATCGCATATGAGTTTGCGAAGCAACAGGGTGTCGTTTATCCTTCATCTTGGGACAAAAATCAAATGGCAGGAATTGATTGGATGGATAACTTCCGAAAACGTCGACCAGAAATACAGTTGAAGAAGGCGCCAAAGACAATAAGAGCCGAAAATGCACAAAATAGTATGGAAGTTGATAGAAATAACGCGTTTTCTTGGAATGATTGGTCTTTTCCTGAACCTGAAAGTCCTCCAGAGATTCAAATTGCACATTGTTGTGGCTACGCTCACGAtgaattacaagaaaaagttgaagCGGGATTCCGTGATTTATATGAAGAAAATACCATTaatcatgaatttttggaACCTGAGATAATCAAATGGGAGCCCCCCATCAGATCTGAGTCCACAATTGTGGAAAATGACGAAATTGCACAAGAAAATTGCTCTATTTGCAATAAATTCTTCCCGGTTCGTCAAAAATCAGCAGGAAATGGTGAAATTACCTTCGATAAACACATGGTACTGGAACATTCGCTCAAAACTTTGAAGGCTTTTCGATGCACGATTTGTGATCTTTACTGCAACACCGAAGTCTATTTCTTAAATCACTTCCGGACCATTCATGAgggcaaacaaaaattatttttctgcgaATTTTGTccggaaaagtttttgttaaagCCAAAATTGGTCGCGCATGTGaagaaattccataaaaacgATGAAATTCGTCTCGTTTGTGACATTTGTCATCTTCAATTTCCTACAAAAGAAAAGTTGGAGAAACATATAGCGGCGAAACACATTAGTACAAGGGAATGTCCGTCGTGCCAcggtaaatttgaaaaaggcAGCAAATACATAAATCATCGAAAATCCTGCGGAAATATTTTCCAATGTCATCTTTGCTCGTCAAGCCTCGTCTCCGCTGCCGCTCTCGAGTACCATATAGCACGTTTCCACGTTCCTTCACCGCCTTGCGAAACTTGTGGCGAAACGTTCGCATGCCAGGCCGACTTGGATCACCACAAAAGACTCACTCACACGACAAAAACGCGAATTTGCGATCAATGTGGCGCCAGTTTCTACACAAGTGGCGGCCTAAAGAGACACATTCGGCACATCCACATGGGCATCAAACACTCAGAAACCGGGAAACAATCGTGGTGCCAAGTTTGCCAAAAACTCGAACCGCATCGCACCAAATTGAAGCACGAAAAGGAAGCGAAACACGGAAGACGTTACAAATGCGACCAATgcgaaaaaagtttcttctcaAATCTGAAACTGAAGAAACATTCTTATGTGCATTCGAAAACGCGTCCTTACAATTGCAAATTATGCGATACGGGATATTATCAATCGTCGTACCTGAAAGCGCATTATCAGAGAGTTCATAATTCGGAATATCTTGGGgcgaataaaaaatga
Protein Sequence: MIRDLKNAGLQIDFMTAEDYVSIRRSGHHERHFVILKEMQEEDVDNIFRVAISISGNKPLPSQMFKKMECGLICKMVRNYKPKTDRPKISEADIAAAVEDVIKHQISVHQAALKHKINQQTLYSRIRKLRSEISLDGSSLENIENVLNDPNISTIVTQKTAKKIFTDQQEEELAKFILDRPDPNITRTQCREIAYEFAKQQGVVYPSSWDKNQMAGIDWMDNFRKRRPEIQLKKAPKTIRAENAQNSMEVDRNNAFSWNDWSFPEPESPPEIQIAHCCGYAHDELQEKVEAGFRDLYEENTINHEFLEPEIIKWEPPIRSESTIVENDEIAQENCSICNKFFPVRQKSAGNGEITFDKHMVLEHSLKTLKAFRCTICDLYCNTEVYFLNHFRTIHEGKQKLFFCEFCPEKFLLKPKLVAHVKKFHKNDEIRLVCDICHLQFPTKEKLEKHIAAKHISTRECPSCHGKFEKGSKYINHRKSCGNIFQCHLCSSSLVSAAALEYHIARFHVPSPPCETCGETFACQADLDHHKRLTHTTKTRICDQCGASFYTSGGLKRHIRHIHMGIKHSETGKQSWCQVCQKLEPHRTKLKHEKEAKHGRRYKCDQCEKSFFSNLKLKKHSYVHSKTRPYNCKLCDTGYYQSSYLKAHYQRVHNSEYLGANKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402689;
90% Identity: iTF_00402689;
80% Identity: iTF_00402689;