Basic Information

Gene Symbol
-
Assembly
GCA_015732765.1
Location
NC:211507516-211510212[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 5.3 1.5e+02 2.9 0.9 2 23 162 184 161 184 0.91
2 16 0.0072 0.21 11.9 0.1 2 20 194 212 194 214 0.94
3 16 0.043 1.2 9.5 0.3 1 20 221 240 221 241 0.96
4 16 0.7 20 5.6 4.2 2 23 332 354 332 354 0.95
5 16 0.75 21 5.5 1.0 2 21 365 384 364 385 0.94
6 16 0.013 0.38 11.1 0.2 2 21 393 412 392 417 0.91
7 16 0.059 1.7 9.0 2.0 2 23 492 514 492 514 0.96
8 16 1.3 36 4.8 0.3 1 21 525 545 525 546 0.91
9 16 0.00076 0.022 15.0 1.1 1 22 554 575 554 579 0.93
10 16 0.22 6.3 7.2 0.1 2 20 634 652 634 654 0.92
11 16 0.0063 0.18 12.1 0.3 1 23 660 683 660 683 0.95
12 16 3.2e-05 0.00092 19.3 0.4 1 23 690 712 690 712 0.97
13 16 0.0002 0.0057 16.8 0.1 2 23 719 741 719 741 0.95
14 16 1.4e-05 0.00041 20.4 0.2 1 23 747 769 747 769 0.97
15 16 0.16 4.6 7.7 4.0 1 23 775 798 775 798 0.96
16 16 0.0012 0.034 14.4 0.7 1 23 804 826 804 826 0.99

Sequence Information

Coding Sequence
ATGGAACCTACGAGCCATTGCCGCATCTGTCACCGCCCGGAGGACGCTTCGATGCCACTACGCTCAATTTACAGCTCGGATGAGTCGGAGGAAATCGTCAAAATGATGGAGGAGTTGAACGGCGGTCAGCTTATCGTTGACGAGCTTCGCTCGTCGGAAATCTGCGCGACGTGCCTGCAAAAGGTCCACATCGGTTACGCCATCCAGCGGCAGATTCGCGAAGCGGAGGCCACCCCAGCAACGAGCTCAACGGAATTAGTTCTACCCTCGGGGACGGTTGTCAAGGTGGAGGACGTGTTCAtcgaggaagaggaggaggacgatGGTTACGAGTACGAATTCTTGGAAGATGAGTATTTGGAGGAGGACCAGCCGGTTCAGCGGGTCGTTCGCGGGAGGTTCTTTGTAATGCCGAAGGAGGAGGTGGTTCGGGGCGTGGTAGAGCATGTGGAAGGGTATCGGGAGGTGCAGATCGAGGGCGATCGGTGCTGCGGGTGCAGCTTTGTGGGGGTGAATAGGAAGGAGCTGTTGCAACATTCGGACAAGGCGCACGTGATTGATAGCGTTGGGAGTGGGAATTATTGTCCGATTTGTTTTGGGAAGTTTTCGCGGGAAGAGACACTGACGAGACACATTGACGAGTGCCGGTCGAGGAGTATTTTCGTGTGTGGGAGATGCAATCGGTACTTTAATCGGCGGGGGAAGATTGAGCGGCACTTGGTGGGTTGTAAGGCGCAGGAAGTTGTTGTTCCGGGGGAGGGAGCTGAGGAGAGTGATACGATGGAGATTGAGTTTGAGACGGGGAGCGAGtgggaagaggaggaggagttcAAGCAGGTGGAGGAAAAATTACGAAGGAAAGTCGCTCCGAAATTGCGAAATGTGGTTGATGTGAGATTCAGCGAAGGACTTCGAATCGACAACTTGCAAGAGTCGCAGATTGTGACAAGGGTCACGTTCCAGACGTTTCAGTACGTGAAGTTGCACGGAGAGCGTTGCTGTGGCTGTGATTTCTTCTGTGAGAAGCGGGAGGAGCTCTTTCGGCATGCTCGAGAAGTTCACGAATCAGTGGAAGGGTTGGAAAGTTTGTTGAAATGTTCGATTTGCTGCGTTGAGTTTGAAGATAATCGCAAGCTGCAGCAGCACATCAATTTCAACACGAGCAAAGAGTTGCTGATTTGCACGATCTGCGACGAGGCATTCTCTGGGACGGGACATTTGCTGTATCACCAGGAGATGAGCTTGTCCCACAAGGATCTCTGCGTAGCACAGAAAGCTCAAATTCTTGAACTGAAAGACAAATCGGTTCGAGAAGAGTTGGTTCGTCTTTCATCCAATGATAAGGATCCAACTCGGCATCGGAATAACAACCGATCCATCACGCGGCACCGTCATCTGTCCCTACCTGAGCCGTGCTTCATAACGGACATCGACGACTTCCTGAACTACCAAATCATAACGGTCAGCGGCGAACGCTGCTGCGGCTGCGGCCAATTCTTCCAGACCTTCAAGGAACTCGTCGAGCACGGTCGTCGCGAGCACTTACTTGAGCATCCGGAAGCCACCGGAGGTTACCAGTGCGACATCTGCTTCTCCCGATTCATGTACGATCGCGGTCTCATCCTGCACCAGTCGACGCGGCGTTCCCTCGACAAAATGTACCACTGCACAATTTGCAATCTGGTCTTTTCAAAGCAGTACAGCATCACCAAGCATCTCCAATCCGCTCCAAATCACAATCTAGAACAGACCCCAAAACCAAATCCAAATCAGTTCCACTGTTGCTTCCCCAAATGCGCTCCAACCTTCCCCTCGGAAGACCTCCTCCTCGAACACTGCATCGCCGAACACGCCGGAAAACGGCGCGAAAACGAATCCGAACGCACCAACGAGGCCAACGTCTGCGTCGGCTGCCTCAAATCCTTCGAAAACACCACCACCCTTGTCTGGCACCGAACGATGCGCTTCACCAAGCGCTACACCTGTCGCTTCTGCCCCCTTGAGTTCACCCGCTGGCCAGCATTCCGCGACCACGAAAACCAAGTCCACCTCGGCAAATCAATCCACTTCCCCTGTGAAACCTGCGGAAAGCTGTTCCGCACCGCCCACTCGCTCAAAGCGCACGCCCTCATCCACTCCGAGGCGCGCTCGGAGGTCTGCGACGAGTGTGGCGCGGCCTTCCGGAACAAGGGCGTCCTCAAGCGGCACAAGCGGGCCGTCCACGCGGCCGAGTTCCGGTTCGATTGTGGGGATTGTGGGAAAAAGTTCCCCACCCGAGAGCAGATGCAGGCGCACAGTCGGGTTCACACCGGGGTTAAACCGTATCCGTGCAGATTCTGCGAGAGGGCGTTCAAGCACTTTACCGACCGGAAGCGGCACGAAATGTCGACGCACACGGGCGAGAGGCCGTACAAGTGTGCGCACTGCTCGGCGGCGTACATCAGGAACAGGGAGTTGGTCATTCATCTGCAGAAGCATAATGGGGAAGGGAAGGAAGGGGACGGTGAGGTTcaataa
Protein Sequence
MEPTSHCRICHRPEDASMPLRSIYSSDESEEIVKMMEELNGGQLIVDELRSSEICATCLQKVHIGYAIQRQIREAEATPATSSTELVLPSGTVVKVEDVFIEEEEEDDGYEYEFLEDEYLEEDQPVQRVVRGRFFVMPKEEVVRGVVEHVEGYREVQIEGDRCCGCSFVGVNRKELLQHSDKAHVIDSVGSGNYCPICFGKFSREETLTRHIDECRSRSIFVCGRCNRYFNRRGKIERHLVGCKAQEVVVPGEGAEESDTMEIEFETGSEWEEEEEFKQVEEKLRRKVAPKLRNVVDVRFSEGLRIDNLQESQIVTRVTFQTFQYVKLHGERCCGCDFFCEKREELFRHAREVHESVEGLESLLKCSICCVEFEDNRKLQQHINFNTSKELLICTICDEAFSGTGHLLYHQEMSLSHKDLCVAQKAQILELKDKSVREELVRLSSNDKDPTRHRNNNRSITRHRHLSLPEPCFITDIDDFLNYQIITVSGERCCGCGQFFQTFKELVEHGRREHLLEHPEATGGYQCDICFSRFMYDRGLILHQSTRRSLDKMYHCTICNLVFSKQYSITKHLQSAPNHNLEQTPKPNPNQFHCCFPKCAPTFPSEDLLLEHCIAEHAGKRRENESERTNEANVCVGCLKSFENTTTLVWHRTMRFTKRYTCRFCPLEFTRWPAFRDHENQVHLGKSIHFPCETCGKLFRTAHSLKAHALIHSEARSEVCDECGAAFRNKGVLKRHKRAVHAAEFRFDCGDCGKKFPTREQMQAHSRVHTGVKPYPCRFCERAFKHFTDRKRHEMSTHTGERPYKCAHCSAAYIRNRELVIHLQKHNGEGKEGDGEVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00400960;
90% Identity
iTF_00400960;
80% Identity
-