Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:14696304-14698988[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 8.7 2.7e+02 2.9 0.9 2 23 166 188 165 188 0.91

2 16 0.033 1 10.5 0.0 2 20 198 216 198 218 0.94

3 16 0.05 1.5 9.9 0.2 1 20 225 244 225 246 0.95

4 16 1 32 5.8 4.0 2 23 336 358 336 358 0.95

5 16 1.2 38 5.5 1.0 2 21 369 388 368 389 0.94

6 16 0.015 0.48 11.5 0.2 2 22 397 417 396 421 0.91

7 16 0.33 10 7.3 3.9 2 23 496 518 496 518 0.96

8 16 2 63 4.8 0.3 1 21 529 549 529 550 0.91

9 16 0.0012 0.038 15.0 1.1 1 22 558 579 558 583 0.93

10 16 0.36 11 7.2 0.1 2 20 638 656 638 658 0.92

11 16 0.01 0.32 12.1 0.3 1 23 664 687 664 687 0.95

12 16 9.2e-05 0.0028 18.5 0.5 1 23 694 716 694 716 0.96

13 16 0.00033 0.01 16.8 0.1 2 23 723 745 723 745 0.95

14 16 4.5e-05 0.0014 19.5 0.3 1 23 751 773 751 773 0.97

15 16 0.26 8 7.6 4.0 1 23 779 802 779 802 0.96

16 16 0.00088 0.027 15.4 1.1 1 23 808 830 808 830 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	8.7	2.7e+02	2.9	0.9	2	23	166	188	165	188	0.91
2	16	0.033	1	10.5	0.0	2	20	198	216	198	218	0.94
3	16	0.05	1.5	9.9	0.2	1	20	225	244	225	246	0.95
4	16	1	32	5.8	4.0	2	23	336	358	336	358	0.95
5	16	1.2	38	5.5	1.0	2	21	369	388	368	389	0.94
6	16	0.015	0.48	11.5	0.2	2	22	397	417	396	421	0.91
7	16	0.33	10	7.3	3.9	2	23	496	518	496	518	0.96
8	16	2	63	4.8	0.3	1	21	529	549	529	550	0.91
9	16	0.0012	0.038	15.0	1.1	1	22	558	579	558	583	0.93
10	16	0.36	11	7.2	0.1	2	20	638	656	638	658	0.92
11	16	0.01	0.32	12.1	0.3	1	23	664	687	664	687	0.95
12	16	9.2e-05	0.0028	18.5	0.5	1	23	694	716	694	716	0.96
13	16	0.00033	0.01	16.8	0.1	2	23	723	745	723	745	0.95
14	16	4.5e-05	0.0014	19.5	0.3	1	23	751	773	751	773	0.97
15	16	0.26	8	7.6	4.0	1	23	779	802	779	802	0.96
16	16	0.00088	0.027	15.4	1.1	1	23	808	830	808	830	0.99

Sequence Information

Coding Sequence: ATGGAACCTACCAGCCATTGCCGCATCTGTCAGCATTCGGAAGACCCATCAGTGCCGCTTCGCTCAATTTACAGCTCGGTTGAGTCGGTTGAAATCGTCAAAATGATGGAGGAGTTGAACGGCGGTCAGCTTATCGTTGACGAGCTTCGCTCGTCGGAAATCTGCGCGACGTGCCTGCAAAAGGTCCACATCGGTTACGCCATCCAGCGGCAGATTCGCGAAGCGGAGGCCACCCCAGCAACGAGCTCAACGGAGTTAGTTCTGCCCTCGGGGACGGTGGTCAAGGTGGAGGACGTGTACATCGAGGAAGAGGCGGAGGAGGAAGACGATGGTTACGAGTACGAATTCTTGGAAGATGAGTACTTGGAGGAGGACCAGGCGGAGCCGGTTCAGCGGGTTGTTCGTGGGAGGTTCTTTATGATGCCGAAGGAGGAGGTGGTTCGGGGCGTGGTTGAGCATGTGGAAGGGTATCGAGAGGTGCAGGTCGAGGGCGATCGGTGCTGCGGGTGCAGCTTTGTGGGGGTAAACAGGAAGGAGCTGTTGCAGCATTCGGACAAGGCGCACGTGATTGATAGCGTTGGGAGTGGGAATTATTGTCCGATTTGTTTTGGGAAGTTTGCGCGGGAAGAGACGCTGACGAGGCACATTGATGAGTGCCGGTCGAGGAGTATTTTCGTGTGTGGGAGATGCAATCGGTACTTTAATCGGCGGGGAAAGATTGAGCGGCATTTGGCGGGTTGTAGGGCGGAGGAAGTTGTCGATCCGGGGGAGGAAGCCGAGGAGAGTGATACGATGGAGATTGAGTTTGAGACGGGGAGCGAGtgggaagaggaggaggagttCAAGCCGGTGGAGGACAAATTACGAAGGAAAGTCGCTCCGAAATTGCGAAATGTGGTTGATGTGAGATTCAGCGAAGGACTTCGAATCGACAACTTGCAAGAGTCGCAGATTGTGACTGGGATCACGTTCCAGACGTTTCAGTACGTGAAGTTGCATGGTGAGCGTTGCTGTGGCTGTGATTTCTTCTGTGAGAAGCGGGAGGAGCTTTTCCGGCATGCTCGAGAAGCTCACGAAGCCGTGGAAGGGTTGGAAAGTTTGCTGAAATGTTCGATTTGCTGCGTTGAGTTTGAAGACAATCGAAAGTTGCAGCAGCACATCAATTTTACCACGAGCAAAGAGTTGCTGATTTGTACGATCTGCGATGAGGCCTTCTCCGGGACCGGACATTTGCTTTACCACCAGGAGACAAGCTTGTCCCACAAGGATCTCTGCGTAGCACAGAAAGCTCAAATTCTTGAACTGAAGGACAAATCGATTCGAGAAGAGTTGGTTCGTCTTTCTTCCAATGATAAGGATCCGACCCGGCATCGGAACAACAATCGGTCCATCACGCGGCACCGTCATCTGTCCCTGCCGGAACCGTGCTTCATAACGGACATCGACGACTTCCCAAACTACCAAATCATAACGGTCAGCGGCGAACGCTGCTGTGGCTGCGGTCAATTCTTCCATACCTTCAAGGAACTCGTCGAGCACGGCCGTCGCGATCACCTGCTGGAGCATCCGGAAGCAACCGGAGGCTACCAGTGCGACATCTGCTTCTCCCGTTTCATGTACGATCGCGGCCTCATCCTGCACCAGTCGACGCGGCGTTCCCTCGACAAAATGTACCACTGCACAATCTGCAATCTGGTCTTTTCGAAGCAGTACAGCATCACAAAGCATCTCCAATCCGCTCCCAATCACAACCTAGAACAGACCCCAAAACCAAACCCAAACCAGTTCCACTGCTGCTTCCCCAAATGCGCACCAACCTTCCCCTCGGAAGACCTCCTCCTCGAACACTGCATCACAGAACACGCCGGCAAACGGCGCGAAAACGAATCCGAACGCACCAACGAGGCCAACGTCTGCGTCGGATGTCTCAAATCCTTCGAAAACACCACCACCCTCGTCTGGCACCGAACGATGCGCTTCACCAAACGCTACACCTGTCGATTCTGCCCCCTGGAATTCACCCGCTGGCCAGCGTTCCGCGACCACGAAAACCAAGTCCACCTCGGCAAATCAATCCACTTCCCCTGTGAAACCTGCGGAAAACTCTTCCGCAACGCCCACTCGCTCAAAGCGCACGGCCTCATCCACTCCGAAGCGCGCTCGGAAGTCTGCGACGAGTGTGGCGCGGCCTTCCGGAACAAGGGCGTCCTCAAGCGGCACAAGCGGGCCGTTCACGCGGCCGAGTTTCGGTTCGATTGCGTCGATTGTGGGAAAAAGTTTCCCACCCGGGAGCAGATGCAGGCGCACAGTCGAGTCCACACCGGAGTTAAACCGTATCCGTGCAGGTTCTGCGAGAGGGCGTTCAAGCACTTTACCGACCGGAAGCGGCACGAAATGTCGACGCACACGGGCGAGCGGCCGTACAAGTGTTCGCACTGCTCGGCGGCTTACATCAGGAACAGGGAGTTGGTTATTCATTTGCAGAAGCACAATGGGGAGGGAAAGGGAGGGGAAGTTGAAggtcaataa
Protein Sequence: MEPTSHCRICQHSEDPSVPLRSIYSSVESVEIVKMMEELNGGQLIVDELRSSEICATCLQKVHIGYAIQRQIREAEATPATSSTELVLPSGTVVKVEDVYIEEEAEEEDDGYEYEFLEDEYLEEDQAEPVQRVVRGRFFMMPKEEVVRGVVEHVEGYREVQVEGDRCCGCSFVGVNRKELLQHSDKAHVIDSVGSGNYCPICFGKFAREETLTRHIDECRSRSIFVCGRCNRYFNRRGKIERHLAGCRAEEVVDPGEEAEESDTMEIEFETGSEWEEEEEFKPVEDKLRRKVAPKLRNVVDVRFSEGLRIDNLQESQIVTGITFQTFQYVKLHGERCCGCDFFCEKREELFRHAREAHEAVEGLESLLKCSICCVEFEDNRKLQQHINFTTSKELLICTICDEAFSGTGHLLYHQETSLSHKDLCVAQKAQILELKDKSIREELVRLSSNDKDPTRHRNNNRSITRHRHLSLPEPCFITDIDDFPNYQIITVSGERCCGCGQFFHTFKELVEHGRRDHLLEHPEATGGYQCDICFSRFMYDRGLILHQSTRRSLDKMYHCTICNLVFSKQYSITKHLQSAPNHNLEQTPKPNPNQFHCCFPKCAPTFPSEDLLLEHCITEHAGKRRENESERTNEANVCVGCLKSFENTTTLVWHRTMRFTKRYTCRFCPLEFTRWPAFRDHENQVHLGKSIHFPCETCGKLFRNAHSLKAHGLIHSEARSEVCDECGAAFRNKGVLKRHKRAVHAAEFRFDCVDCGKKFPTREQMQAHSRVHTGVKPYPCRFCERAFKHFTDRKRHEMSTHTGERPYKCSHCSAAYIRNRELVIHLQKHNGEGKGGEVEGQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402061; iTF_00400980;
90% Identity: iTF_00402061; iTF_00400980;
80% Identity: -