Basic Information

Gene Symbol
-
Assembly
GCA_015732765.1
Location
NC:41343562-41350033[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 7 2e+02 2.5 3.8 1 18 67 84 67 90 0.89
2 23 0.057 1.6 9.1 7.7 1 23 97 119 97 119 0.99
3 23 0.07 2 8.8 2.0 1 17 161 176 161 177 0.87
4 23 0.0061 0.17 12.1 7.6 1 23 191 213 191 213 0.98
5 23 0.033 0.94 9.8 0.5 1 15 257 271 257 274 0.87
6 23 0.12 3.5 8.0 0.8 2 23 288 309 287 309 0.97
7 23 4.7e-05 0.0013 18.8 1.3 1 23 322 344 322 344 0.97
8 23 0.002 0.057 13.6 2.3 1 23 351 373 351 373 0.98
9 23 5.7 1.6e+02 2.8 0.1 1 12 394 405 394 408 0.85
10 23 0.0025 0.072 13.3 1.0 1 23 424 446 424 446 0.98
11 23 0.023 0.65 10.3 1.1 3 23 484 504 482 504 0.95
12 23 0.00091 0.026 14.7 1.2 2 23 614 635 613 635 0.97
13 23 0.0035 0.1 12.9 5.3 2 23 643 664 642 664 0.97
14 23 0.0014 0.039 14.2 3.5 1 23 684 706 684 706 0.97
15 23 0.02 0.58 10.5 3.7 1 23 714 736 714 736 0.98
16 23 0.013 0.37 11.1 1.6 2 20 772 790 771 790 0.94
17 23 0.88 25 5.3 1.4 1 23 858 880 858 880 0.97
18 23 0.94 27 5.2 4.8 1 23 888 910 888 910 0.98
19 23 0.0005 0.014 15.5 2.2 1 23 915 937 915 937 0.97
20 23 0.31 8.7 6.8 3.6 1 23 958 980 958 980 0.97
21 23 0.039 1.1 9.6 0.8 1 23 985 1008 985 1008 0.96
22 23 0.0016 0.046 13.9 1.9 1 23 1013 1035 1013 1035 0.97
23 23 0.015 0.44 10.9 3.4 1 23 1049 1071 1049 1071 0.97

Sequence Information

Coding Sequence
ATGGCAACGGAAATTTTTTCCGAACAGTTGCACCAAACTCATGTGTTTACGGTTGTGAAAGAGGAGCCTCCAGAGATTGACCCGGGAGCCGCGTCATTCTGCTACGAAACGGTGATCAAGGAGGAAGTTATTCTGGAGGATCCGGTTGAACGTGCCGACGATCTGCCAGAACCAACAGAAATCCCAAAAGAGCACCCCTTTAAATGTTTCGAATGTTATCGAACGTTTGCTatagaaaacaatttgaaaaaatgtttaaaaagacACCATGCCATTAGAAATAAACTTTACCAATGTAAATTTTGTGGAAagtgtTGTGGTACTAAGCAAGACAACGACAGACACAAGAGATCCCACaagagaaatttgaagaaattaaagCCGCCTGTTCAagatattgaaataaataaacaggAGCAGCCAGAACCTGTGGGCGAAAGCCCTAGCGGAAATTCAAcggaaatttcaaaaagccACCGCTTTAAATGTTCCGAGTGCAGCAAAACATTTGATAAAAAGCATCTGCGTCAAAGATGTGAGTGGAAGCACAAGGTTATTAAAAGTGAGCGGTACAAGTGTGAAACATGTGGAAAGCTTTGTTGTTCCAAGTTTAACCTTACCAGGCATGAGTTCACCCACAAAAACGAACAACAACAGCCAAAATCCGGTGGAGATCTGCCGAGTTCAGAGGAGAAAAATTCAATGACGCCCAATGAGGACAGCAATGAAAACGAAAGTGAAGAATCGGACGAGTCTTCCGAAAATTGTTACAAATGTCCCGAGTGCCCACGCAGGTTCAAAGAACGGTACCAGGCCAATAGATGTAAAAAGCAGCACTTGGCCAAACGGTTAGGATTGACCGAGTGCAAATTGTGTAAAAAGCAATTGGGAACCATACGTGATCTTAAAAATCATGAACTTACTCACAGTAGAGTAAAAACCCCCGTAGTTAAGCCAGCGTACTTTGCGTGCGAAATTTGCGATAAGcgcTATGTCAAGAAGAAAAGCATCAAAAAACACATGCTTACTCACCAAGAAGGGGCACTTCTGTTCAAATGCCACACGTGCAATGTGAAATTCCCAACAAGGGCGGAGATGCTTACGCACATCACAAGACACGACTGGAACGAAACAAAGCATAGTTATGCCGCAAAGCTGGTTAAGGAAGACGACGGCAACTATTTATGTACGGTTTGCAGCAGGAGATTCATCAACCTGAGAACGGGCATTCCCCACGTGTTCCGGCATATGAACATAATTGAAGCGCTTTTCGAGTGCAAATCGTGTGGACTGCGATGTGGAGATGCATACGAGTACAAGATACACATTCAAACTCACAAGAAACCGGAAGAGGCAACGGATGCTTCCGATGGGAAACCACCTGCGGAAGAACCAGATTCGACTTCGTCGAAGGAAAGTGCTGCTACGCAAAAATCTACCCAACTTGACTGCAGAACTTGTCGAAAGCGCCTACGCAACAAGCAATCCCTCGAGAGGCACGAGATTATCCATCGGATACGAAAGAAGCGGACCGATGATGTCGCAGAACCGGAACAAGCGGCGGAAGAGGGGAATAAGACTGAAGAAACTGGCGCCTCTTTTTGCTACGAAACGGTGACGAAGGAAGAACTGATCATTGAGGACGATGCGGTAGAGGAATCAGGGGAGGACGAGGGGCAGGAAGAAGTTCCTCGAAATTCGTTGGAAGGTAGTCAAGTTAAGGAGGATGAGACCGGAAGAGGACAGGAGGAAGATTCTAGGGAATCTCTGAAGGAACAAAGTAAACCTAAGGAGGGCGAGCTTCCCAACAAAGAAACCCCAGGTCAAGTTATTCCCAAACAATGCGATATCTGTCAGAAGatTTTCACGAATAGACGTAATGCTGCATCACACAGGCAGTCTCACGAAAAGAGTGAAATTCCTCTAGAGTGCAGGAAATGCCATGAAAAATTTGATACTAGATACAGTTTGTTGGCGCACCATAAAACCCACGCAAATGATGAGGTTAAATCGAAGTATAAATATTTGATGGTCGAAGATGAGGAAGGTCACAGATGTTTGCTGTGCGAGACTAGGTTCAGCACTAGGAGTAAACTATTTGCTCATGTACAAAGACACATGAATGTTATCGAGGGCGTTTATCACTGTAAAGTCTGTGGTTTGCGATGCGGCGAAAACTACGACTATCAGCTGCACATCAAAACTCACAAGAACATGTCCAATCAAAAGGCACTTCCGAGAGAGATTGAAGGCGTTCACACCGACTACGATTCATCGAGTAAAGTGGCCTGCGAAAAGTCGGATCTGCCACTGCACTGTAAGACATGCAACGTGTTCTTCAACAACAAGACAAATCTGAACGTTCACCTGTGGAAGTCGAAGCTTAGATTCTTAGAGTTAAACAATACAACTCATGAAAAAGAGCCACCCGTTGAGAAGAAAAAACCAGTTGTTTCTAAAGTTAAGTCGCAACCGACACAACGTGGTCTAAGGATTAGGaAAGGTAGAAGCAAAACGAATCGTCTTCTCCCGAGAGATGATTCGAAAATTTTCACGGATGAAAATGGCTTCTACAACTGCACCAAGTGCGCCTATAAGACGGTTAAATCAAAACTGTTCAGAGGTCATGTTCGTGGCCATAAGGCGGTTGAGGTTGGCTTGTACACGTGCGAGGTGTGTCAAATGCGCTTACCAGACAAAGAGCATCTGTTTTGTCATAAGAAAACTCATTTAAAGGAAAGATTTGAGTGTCTTACATGCCATCAGaaatttgcaacaaaagGTGAACTCTTCAAGCATCGAATCATTCATACCAAGAACGTGACAACGAAGCAATTTATGGAGAAAGTTACCGAGGACGAGAAGGGCGTTTTCACCTGTTCAATTTGTGGCAAAACACACACGGAACGGAAGTACGCCTTTGCACACTTTCGCACACACGTGACGGAAAAATTCGTGTGCCAAATATGTGAAAAGCGCTGCGCATCTAAAAACATTCTCATCCAACACATCGAAAGTCAACACGAAAAACTGCGGTTCAGGTGCAGCACGTGCAAAGAGAGATTTGAGACCAGACCCGCCCTGTTTCGACACAAACAGGAGCACAAATCAGATTTGAAAGTGATTCTGCAGAATGATGACCGCTACCATTGTACGCGGTGTGACAAAACGTATGCCAGGCGGGATAATGCTTTGCTGCACTTTAAATCGCATTCGaaaaacaaaaataagtcgGATGAAGAGCAACAGATAAAGGAAGACAACGCAACCGAGGAAGATCGAGATTCGCGGGAAAATTCTCTGAATAATGAAGAGCTGGACTCGTGA
Protein Sequence
MATEIFSEQLHQTHVFTVVKEEPPEIDPGAASFCYETVIKEEVILEDPVERADDLPEPTEIPKEHPFKCFECYRTFAIENNLKKCLKRHHAIRNKLYQCKFCGKCCGTKQDNDRHKRSHKRNLKKLKPPVQDIEINKQEQPEPVGESPSGNSTEISKSHRFKCSECSKTFDKKHLRQRCEWKHKVIKSERYKCETCGKLCCSKFNLTRHEFTHKNEQQQPKSGGDLPSSEEKNSMTPNEDSNENESEESDESSENCYKCPECPRRFKERYQANRCKKQHLAKRLGLTECKLCKKQLGTIRDLKNHELTHSRVKTPVVKPAYFACEICDKRYVKKKSIKKHMLTHQEGALLFKCHTCNVKFPTRAEMLTHITRHDWNETKHSYAAKLVKEDDGNYLCTVCSRRFINLRTGIPHVFRHMNIIEALFECKSCGLRCGDAYEYKIHIQTHKKPEEATDASDGKPPAEEPDSTSSKESAATQKSTQLDCRTCRKRLRNKQSLERHEIIHRIRKKRTDDVAEPEQAAEEGNKTEETGASFCYETVTKEELIIEDDAVEESGEDEGQEEVPRNSLEGSQVKEDETGRGQEEDSRESLKEQSKPKEGELPNKETPGQVIPKQCDICQKIFTNRRNAASHRQSHEKSEIPLECRKCHEKFDTRYSLLAHHKTHANDEVKSKYKYLMVEDEEGHRCLLCETRFSTRSKLFAHVQRHMNVIEGVYHCKVCGLRCGENYDYQLHIKTHKNMSNQKALPREIEGVHTDYDSSSKVACEKSDLPLHCKTCNVFFNNKTNLNVHLWKSKLRFLELNNTTHEKEPPVEKKKPVVSKVKSQPTQRGLRIRKGRSKTNRLLPRDDSKIFTDENGFYNCTKCAYKTVKSKLFRGHVRGHKAVEVGLYTCEVCQMRLPDKEHLFCHKKTHLKERFECLTCHQKFATKGELFKHRIIHTKNVTTKQFMEKVTEDEKGVFTCSICGKTHTERKYAFAHFRTHVTEKFVCQICEKRCASKNILIQHIESQHEKLRFRCSTCKERFETRPALFRHKQEHKSDLKVILQNDDRYHCTRCDKTYARRDNALLHFKSHSKNKNKSDEEQQIKEDNATEEDRDSRENSLNNEELDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00400892;
90% Identity
iTF_00400892;
80% Identity
-