Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:181980947-181988454[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.12 3.6 8.7 8.2 1 23 97 119 97 119 0.99

2 22 0.11 3.5 8.8 2.0 1 17 161 176 161 177 0.87

3 22 0.0099 0.3 12.1 7.6 1 23 191 213 191 213 0.98

4 22 0.054 1.7 9.8 0.5 1 15 257 271 257 274 0.87

5 22 0.2 6.1 8.0 0.8 2 23 288 309 287 309 0.97

6 22 5.4e-05 0.0017 19.2 0.7 1 23 322 344 322 344 0.97

7 22 0.0033 0.1 13.6 2.3 1 23 351 373 351 373 0.98

8 22 9.3 2.9e+02 2.8 0.1 1 12 394 405 394 408 0.85

9 22 0.0041 0.13 13.3 1.0 1 23 424 446 424 446 0.98

10 22 0.035 1.1 10.4 0.9 3 23 484 504 482 504 0.95

11 22 0.0015 0.045 14.7 1.2 2 23 614 635 613 635 0.97

12 22 0.0057 0.18 12.9 5.3 2 23 643 664 642 664 0.97

13 22 0.0022 0.067 14.2 3.5 1 23 684 706 684 706 0.97

14 22 0.033 1 10.5 3.7 1 23 714 736 714 736 0.98

15 22 0.021 0.65 11.1 1.6 2 20 772 790 771 790 0.94

16 22 0.1 3.1 9.0 1.7 1 23 858 880 858 880 0.97

17 22 1.5 47 5.2 4.8 1 23 888 910 888 910 0.98

18 22 0.0015 0.047 14.7 3.5 1 23 915 937 915 937 0.97

19 22 0.5 15 6.8 3.6 1 23 958 980 958 980 0.97

20 22 0.064 2 9.6 0.8 1 23 985 1008 985 1008 0.96

21 22 0.0026 0.08 13.9 1.9 1 23 1013 1035 1013 1035 0.97

22 22 0.0031 0.094 13.7 1.9 1 23 1049 1071 1049 1071 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.12	3.6	8.7	8.2	1	23	97	119	97	119	0.99
2	22	0.11	3.5	8.8	2.0	1	17	161	176	161	177	0.87
3	22	0.0099	0.3	12.1	7.6	1	23	191	213	191	213	0.98
4	22	0.054	1.7	9.8	0.5	1	15	257	271	257	274	0.87
5	22	0.2	6.1	8.0	0.8	2	23	288	309	287	309	0.97
6	22	5.4e-05	0.0017	19.2	0.7	1	23	322	344	322	344	0.97
7	22	0.0033	0.1	13.6	2.3	1	23	351	373	351	373	0.98
8	22	9.3	2.9e+02	2.8	0.1	1	12	394	405	394	408	0.85
9	22	0.0041	0.13	13.3	1.0	1	23	424	446	424	446	0.98
10	22	0.035	1.1	10.4	0.9	3	23	484	504	482	504	0.95
11	22	0.0015	0.045	14.7	1.2	2	23	614	635	613	635	0.97
12	22	0.0057	0.18	12.9	5.3	2	23	643	664	642	664	0.97
13	22	0.0022	0.067	14.2	3.5	1	23	684	706	684	706	0.97
14	22	0.033	1	10.5	3.7	1	23	714	736	714	736	0.98
15	22	0.021	0.65	11.1	1.6	2	20	772	790	771	790	0.94
16	22	0.1	3.1	9.0	1.7	1	23	858	880	858	880	0.97
17	22	1.5	47	5.2	4.8	1	23	888	910	888	910	0.98
18	22	0.0015	0.047	14.7	3.5	1	23	915	937	915	937	0.97
19	22	0.5	15	6.8	3.6	1	23	958	980	958	980	0.97
20	22	0.064	2	9.6	0.8	1	23	985	1008	985	1008	0.96
21	22	0.0026	0.08	13.9	1.9	1	23	1013	1035	1013	1035	0.97
22	22	0.0031	0.094	13.7	1.9	1	23	1049	1071	1049	1071	0.98

Sequence Information

Coding Sequence: ATGGCAACGGAAATTTTTTCCGAAGAGTTGCACCAAACTCATGTGTTTACGGTTGTGAAAGAGGAGCCTCCGGAGATTGACCCGGGAGCCGCGTCATTCTGCTACGAAACGGTGATCAAGGAGGAAGTTATTCTGGAGGATCCGGTTGAACGTGCCGACGATCTGCCAGAACCAACAGAAATCCCAAAAGAGCACCCCTTTAAATGTTTCGAATGTTATCGAACGTTTGCTatagaaaacaatttgaaaaaatgtttaaaaagacaCCATGCCATTAGAAATAAACTTTACAAATGTAAATTTTGTGGAAagtgtTGTGGTACTAAGCAAGACAACGACAGACACAAGAGATCCCACaagagaaatttgaagaaattaaagCCGCCTGTTCAagatattgaaataaataaacagaAGCAGCCAGAATCTGTGAGCGAAAGCCCTAGCGGAAATTCAAcggaaatttcaaaaagccACCGCTTTAAATGTTCCGAGTGCAGCAAAACATTTGATAAAAAACATCTGCGTCAAAGATGTGAGTGGAAGCACAAGGTTATTAAAAGTGAGCGGTACAAGTGTGAAACATGTGGAAAGCTTTGTTGTTCCAAGTTTAACCTTACCAGGCATGAGTTCACCCACAAAAACGAACAACAACAGCCAAAATCCGGTGGAGATCTGCCGAGTTCAGAGGAGAAAAATTCAATGACGCCCAATGAGGACAGCAATGAAAACGAAAGTGAAGAATCGGACGAGTCATCCGAAAATTGTTACAAATGTCCCGAGTGCCCACGCAGGTTCAAAGAACGGTACCAGGCCAATAGATGTAAAAAGCAGCACTTGGCCAAACGGTTAGGATTGACCGAGTGCAAATTGTGTAAAAAGCAATTGGGAACCATACGTGATCTTAAAAATCATGAACTTACTCATAGTAGAGTAAAAACCCCCGTAGTTAAGCCAGCGTACTTTGCGTGCGAAATTTGCGATAAGcgcTATGTCAAGAAGGAAAGCATAAAAAAACACATGCTTACTCACCAAGAAGGGGCACTTCTGTTCAAGTGCCATACGTGCAATGTGAAATTCCCAACTAGGGCGGAGATGCTTACGCACATCACAAGACACGACTGGAACGAAACAAAGCATAGTTATGCCGCAAAGCTGGTTAAGGAAGACGACGGCAACTATTTATGTACGGTTTGCAGCAGGAGATTCATCAACCTGAGAACGGGCATTCCCCACGTGTTCCGGCATATGAACATAATTGAAGCGCTTTTCGAGTGCAAATCGTGTGGACTGCGATGTGGAGATGCATACGAGTACAAGATACACATTCAAACTCACAAGAAACCGGAAGAGGCAACGGATGCTTCCGATGGGAAACCACCTGCGGAAGAACCAGATTCGACTTCGTCGAAGGAAAGTGCTGCTACGCAAAAATCTACCCAACTTGACTGCAGAACTTGTCGAAAGCGCCTACGCAACCAGCAATCCCTCGAGAGGCACGAGATTATCCATCGGATACGAAAGAAGCGGACCGATGATGTCGCAGAACCGGAACAAGCGGCGGAAGAGGGGAATAAGACTGAAGAAACTGGCGCCTCTTTTTGCTACGAAACGGTGACGAAGGAAGAGCTGATCATTGAGGACGATGCGGTAGAGGAATCAGGAAAGGACGAGGGGCAGGAAGAAGTTCCTCGAAATTCGTTGGAAGGTAGTCAAGTCAAGGAGGATGAGACCGGAAGAGGACAGGAGGAAGATTCTAGGGAATCTCTGAAGGAACAAAGTGAACCTAAGGAGGGCGAGCTTCCAAACAAAGAAACCCCAGGTCAAGTTATTCCCAAACAATGCGATATCTGTCAGAAGATTTTCACGAATAGACGTAATGCTGCATCACACAGGCAGTCTCACGAAAAGAGTGAAATTCCTCTAGAGTGCAGGAAATGCCATGAAAAATTTGATACTAGATACAGTTTGTTGGCGCACCATAAAACCCACGCAAATGATGAGGTTAAATCGAAGTATAAATATTTGATGGTCGAAGATGAGGAAGGTCACAGATGTTTGCTGTGCGAGACTAGGTTCAGCACTAGGAGCAAACTATTTGCTCATGTGCAAAGACACATGAATGTTATCGAGGGCGTTTATCACTGTAAAGTCTGTGGTTTGCGATGCGGCGAAAACTACGACTATCAGCTGCACATCAAAACCCACAAGAACATGTCCAATCAAAAGGCACTTCCGAGAGAGATTGAAGGCGTTCACACCGACTACGATTCATCGAGTAAAGTGGCCTGCGAAAAGTCGGATCTGCCACTGCACTGTAAGACATGCAACGTGTTCTTCAACAACAAGACTAATCTGAACGTTCATCTGTGGAAGTCGAAGCTTAGATTCTTAGagTTAAACAATACAACTCATGAAAAAGAGCCACCCGTTGGGAAGAAAAAACCAGTTGTTCCTAAAGTTAAGTCGCAACCGACACAACGTGGTCTAAGGATTAGGaAAAGTAGAAGCAAAACGATTCGTCTTCTCCCGAGAGATGATTCGAAAATTTTCACGGATGAAAATGGCTTCTACAACTGCACCAAGTGCGACTATAAGACGGTTAAATCAAAACTGTTCAGAGGTCATGTTCGTGGCCATAAGGCGGTTGAGGTTGGCTTGTACACGTGCGAGGTGTGTCAAATGCGCTTACCAGACAAAGAGCATCTGTTTTGTCATAAGAAAACTCATTTAAAGGAAAGATTTGAATGTCTTACATGCCATCAGaaatttgcaacaaaaaaggATCTTTTCAAACATCGAATCATTCATACCAAGAACGTGATAACGAAGCAATTTATGGAGAAAGTTACCGAGGACGAGAAGGGCGTTTTCACCTGTTCAATTTGTGGCAAAACACACACGGAACGGAAGTACGCCTTTGCACACTTTCGCACACACGTGACGGAAAAATTCGTGTGCCAAATATGTGAAAAGCGCTGCGCATCTAAAAACATTCTCATCCAACACATCGAAAGTCAACACGAAAAACTGCGGTTCAGGTGCAGCACGTGCAAAGAGAGATTTGAGACCAGACCCGCCCTGTTTCGACACAAACAGGAGCACAAATCAGATTTGAAAGTGATTCTGCAGAAGGATGACCGCTACCGTTGTACGCGGTGTGACAAAACGTATGCCAGGCGGGATAATGCTTTGCTGCACTTTAAATCGCATTCGaaaaacaaaaataagtcgGATGAAGAGCTACAGATAAAGGAAGACAACGCAACCGAGGAAGATCGAGATTCGCGGGAAAATTCTCTGAATAATGAAGAGCTGGACTCGTGA
Protein Sequence: MATEIFSEELHQTHVFTVVKEEPPEIDPGAASFCYETVIKEEVILEDPVERADDLPEPTEIPKEHPFKCFECYRTFAIENNLKKCLKRHHAIRNKLYKCKFCGKCCGTKQDNDRHKRSHKRNLKKLKPPVQDIEINKQKQPESVSESPSGNSTEISKSHRFKCSECSKTFDKKHLRQRCEWKHKVIKSERYKCETCGKLCCSKFNLTRHEFTHKNEQQQPKSGGDLPSSEEKNSMTPNEDSNENESEESDESSENCYKCPECPRRFKERYQANRCKKQHLAKRLGLTECKLCKKQLGTIRDLKNHELTHSRVKTPVVKPAYFACEICDKRYVKKESIKKHMLTHQEGALLFKCHTCNVKFPTRAEMLTHITRHDWNETKHSYAAKLVKEDDGNYLCTVCSRRFINLRTGIPHVFRHMNIIEALFECKSCGLRCGDAYEYKIHIQTHKKPEEATDASDGKPPAEEPDSTSSKESAATQKSTQLDCRTCRKRLRNQQSLERHEIIHRIRKKRTDDVAEPEQAAEEGNKTEETGASFCYETVTKEELIIEDDAVEESGKDEGQEEVPRNSLEGSQVKEDETGRGQEEDSRESLKEQSEPKEGELPNKETPGQVIPKQCDICQKIFTNRRNAASHRQSHEKSEIPLECRKCHEKFDTRYSLLAHHKTHANDEVKSKYKYLMVEDEEGHRCLLCETRFSTRSKLFAHVQRHMNVIEGVYHCKVCGLRCGENYDYQLHIKTHKNMSNQKALPREIEGVHTDYDSSSKVACEKSDLPLHCKTCNVFFNNKTNLNVHLWKSKLRFLELNNTTHEKEPPVGKKKPVVPKVKSQPTQRGLRIRKSRSKTIRLLPRDDSKIFTDENGFYNCTKCDYKTVKSKLFRGHVRGHKAVEVGLYTCEVCQMRLPDKEHLFCHKKTHLKERFECLTCHQKFATKKDLFKHRIIHTKNVITKQFMEKVTEDEKGVFTCSICGKTHTERKYAFAHFRTHVTEKFVCQICEKRCASKNILIQHIESQHEKLRFRCSTCKERFETRPALFRHKQEHKSDLKVILQKDDRYRCTRCDKTYARRDNALLHFKSHSKNKNKSDEELQIKEDNATEEDRDSRENSLNNEELDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402001;
90% Identity: iTF_00402001;
80% Identity: -