Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: TSHZ1
Assembly: GCA_015732765.1
Location: NC:77955128-77957233[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 5.4 1.5e+02 2.8 0.1 1 17 6 22 6 23 0.89

2 14 0.0038 0.11 12.8 0.9 2 23 89 111 88 111 0.95

3 14 0.013 0.38 11.1 4.3 1 20 119 138 119 140 0.95

4 14 0.026 0.74 10.1 8.4 1 23 150 173 150 173 0.97

5 14 0.23 6.5 7.2 1.7 1 23 204 227 204 227 0.96

6 14 0.00034 0.0096 16.1 0.8 1 23 234 257 234 257 0.95

7 14 0.0014 0.039 14.2 2.6 1 23 367 390 367 390 0.94

8 14 0.0066 0.19 12.0 0.2 2 23 396 417 395 417 0.95

9 14 0.0018 0.05 13.8 5.8 1 21 457 477 457 478 0.95

10 14 0.00025 0.0071 16.5 1.6 3 23 501 521 499 521 0.96

11 14 7.9e-06 0.00023 21.2 0.4 1 23 527 550 527 550 0.97

12 14 4.2e-05 0.0012 18.9 3.5 1 23 556 579 556 579 0.97

13 14 0.00017 0.0049 17.0 1.0 1 23 585 608 585 608 0.90

14 14 0.00013 0.0037 17.4 0.1 1 23 614 637 614 637 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	5.4	1.5e+02	2.8	0.1	1	17	6	22	6	23	0.89
2	14	0.0038	0.11	12.8	0.9	2	23	89	111	88	111	0.95
3	14	0.013	0.38	11.1	4.3	1	20	119	138	119	140	0.95
4	14	0.026	0.74	10.1	8.4	1	23	150	173	150	173	0.97
5	14	0.23	6.5	7.2	1.7	1	23	204	227	204	227	0.96
6	14	0.00034	0.0096	16.1	0.8	1	23	234	257	234	257	0.95
7	14	0.0014	0.039	14.2	2.6	1	23	367	390	367	390	0.94
8	14	0.0066	0.19	12.0	0.2	2	23	396	417	395	417	0.95
9	14	0.0018	0.05	13.8	5.8	1	21	457	477	457	478	0.95
10	14	0.00025	0.0071	16.5	1.6	3	23	501	521	499	521	0.96
11	14	7.9e-06	0.00023	21.2	0.4	1	23	527	550	527	550	0.97
12	14	4.2e-05	0.0012	18.9	3.5	1	23	556	579	556	579	0.97
13	14	0.00017	0.0049	17.0	1.0	1	23	585	608	585	608	0.90
14	14	0.00013	0.0037	17.4	0.1	1	23	614	637	614	637	0.95

Sequence Information

Coding Sequence: ATGTGTGTTAACGGTTTTGTTTGTCGCTTATGCTCCAAAGAATCGACAAAATCAGTCGATTTAGAGGCAACAAGCAATGGTGCTTTCAAGAAAATGTTTGATATTTTCCTGTTTCCAAAGAAGCTGCAGCTGCCTCAATCAATTTGCGAAGAATGCACGTACCAAGTCGAATCCTGCAACAGATTCTTCCAACTAGTCATTCAGTACATTGAAACTAATGACTCAACTCAAGAACCACAAAACGACGCAGAAGAAACGCCTCAAACCTGCGATGATTGCCATTCAGCCTTTACAACCGACCTCGACCTGGAACGCCACCAAAAGCTCGTCCACATCGGTCTGGTTAACCGAAACTTCCAATGTCTCACCTGCAGAAAGCACTTCAAAACCAGCCGAGGCTTGCAACAACACACGACTCATTGCCAAAACTCCACCGGCAACGAATCTTTCCACTGCACGCACTGCTCCCGAGACTTTGCGACCAGCACGAGCTACACGAACCACGTGAGGAGCTGCCACGCGGAAGCGATTTGCTATTTCTGCGACCACGGCTGGAGTACGGAGCAGAAGCTGCTGGACCACGTTCGCGAGGCCCACAAGGACAAGCTGTTCATCTGCAAGCGATGCTCCAAGACGGAACGGTTGAGGAAAACTCTGAACCGACACGTTCGGTTGGTGCACGGAGTTTTGGACAGGGAATTTTACTGCGGGCACTGTGAGATGACCTTTGAGGATGTTTCTTCGTTGAGCAAGCACATCCAGGGGAGTCACGCGAACTCGGAGGAAGCTGGACGCGCTTACGAAGAGTTGCTGAACGATTCGCTGTTTCCGAAGGAGGTTGGGCTGGACATGGAACAGGACAGAGAAGAGCAGGAGGAGCACCAGGAAacgtttttgaagcattttaatCTGGTCCGGAGTGCAAACTCCGCAGGCAAATCCAAACCCAACCCAAATAAGATGATTTTGGAGGAGTTTCTGGACGAGGCATTCGAGAACGACCAAATTTGGACCAAATACATTGCTGGAGGTGAAGAATACCTCATCGATAACTACGAATTCTACCTTGATGGACCGTCGCAAGCCGCCCCAAGCAATTACAAATGTCCTCGATGTGAGGAAGGATTCAACAAGCAATGTCACTTGACTGTCCACTTGGCTGAGCAACACAACATTCGGTGTTTAATTTGCAACGATTGTGGAGCCAACTTCAACCGCATCATCGAGTACAAAAGCCATCGCCAAGAGCATCTGAAGGACAACACTAAATTCAGGGAAAACGTAATTCCCGAAGCCGAGGAAGCCCTATCCCTGGTGCAGCGAGAGGAGAAAGAGTACGTCCTAACGGAAAACGAGATGGGATACACTTTCACCTGCAAGCTGTGCGAACGAACGTTTGCGAAAAAATGCAACCTCGAAAAGCATCAATGCTCGTTCTACAACGGTCAGCCAAAAGCAACCTCAACCAGCACTCCCTCAACATCGAGCGACAGCCTGTTCTGCACGCTGTGCGACCGCAAGTTCACCTCCATTTCCGGCCTCAAGTACCACCTGAAGCGGCATACCGACGTTAAAGCGTTCCCCTGCTTGTACTGCAACCAAAAGTTCACCGCCAACTCCAACCTGAACGCCCACATCCGAAACGTCCACAGCGAGAGCAAGAACCACGTGTGCCCCCACTGCGAGCTGCGGTTCGCCGGGAAGGACCACCTGATCAAGCACATTCGGTCACGACACGAAAAGGATCGCGCCTTTGCGTGCACGGAATGCTCGAAGAGTTACTTTCAGAAATCTCACCTAAACGACCACGTGGCAGCGGTCCACTCGGGCTACAAGGCGTTCTCGTGCGAGCAGTGCGGCGCTTCGTACAGCGGCAAGGGCTCCCTGCGGAGACACGTGGCCAAAGCGCACAGTAAAGGCGAATAA
Protein Sequence: MCVNGFVCRLCSKESTKSVDLEATSNGAFKKMFDIFLFPKKLQLPQSICEECTYQVESCNRFFQLVIQYIETNDSTQEPQNDAEETPQTCDDCHSAFTTDLDLERHQKLVHIGLVNRNFQCLTCRKHFKTSRGLQQHTTHCQNSTGNESFHCTHCSRDFATSTSYTNHVRSCHAEAICYFCDHGWSTEQKLLDHVREAHKDKLFICKRCSKTERLRKTLNRHVRLVHGVLDREFYCGHCEMTFEDVSSLSKHIQGSHANSEEAGRAYEELLNDSLFPKEVGLDMEQDREEQEEHQETFLKHFNLVRSANSAGKSKPNPNKMILEEFLDEAFENDQIWTKYIAGGEEYLIDNYEFYLDGPSQAAPSNYKCPRCEEGFNKQCHLTVHLAEQHNIRCLICNDCGANFNRIIEYKSHRQEHLKDNTKFRENVIPEAEEALSLVQREEKEYVLTENEMGYTFTCKLCERTFAKKCNLEKHQCSFYNGQPKATSTSTPSTSSDSLFCTLCDRKFTSISGLKYHLKRHTDVKAFPCLYCNQKFTANSNLNAHIRNVHSESKNHVCPHCELRFAGKDHLIKHIRSRHEKDRAFACTECSKSYFQKSHLNDHVAAVHSGYKAFSCEQCGASYSGKGSLRRHVAKAHSKGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400962;
90% Identity: iTF_00400962;
80% Identity: -