Cpip015686.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NC:108570241-108572349[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.028 0.86 10.7 1.0 2 23 89 111 88 111 0.95 2 13 0.016 0.48 11.5 4.5 1 21 119 139 119 140 0.95 3 13 0.4 12 7.1 7.6 1 23 150 173 150 173 0.97 4 13 0.35 11 7.3 2.2 1 23 204 227 204 227 0.96 5 13 0.0017 0.053 14.5 0.5 1 23 234 257 234 257 0.95 6 13 7.9 2.4e+02 3.0 7.3 1 23 367 390 367 390 0.88 7 13 0.005 0.15 13.1 0.3 2 23 396 417 395 417 0.95 8 13 0.0029 0.088 13.8 5.8 1 21 457 477 457 478 0.95 9 13 0.0004 0.012 16.5 1.6 3 23 501 521 499 521 0.96 10 13 1.3e-05 0.00039 21.2 0.4 1 23 527 550 527 550 0.97 11 13 6.6e-05 0.002 19.0 4.3 1 23 556 579 556 579 0.97 12 13 0.00032 0.0097 16.8 0.9 1 23 585 608 585 608 0.90 13 13 0.00021 0.0064 17.4 0.1 1 23 614 637 614 637 0.95
Sequence Information
- Coding Sequence
- ATGTGTGTAAACGGTTTCGTTTGTCGCTTGTGTTCCATGGAATCGACAAAATCCATCGATTTAGAAGCAACAAGCAACGTTGGTTTAAAGAAAATGTTTGATGTTTTTATGTTTCCAAAGAAGCTGCAGCTACCCCACTCAATTTGCGAAGAATGCTCGAACCAAGCACAAACCTGCTACAGATTCTTCCAACTAATCATTCAGTACATCGAAGCCAATGACTCAACTCAAGAACCACAAAACGATGCAGAAGAAACACTTCAAACCTGTGATGTTTGCCATTCAGCCTTTACAACCGACCTCGACCTGGAACGCCACCGAAAGCTCGTCCACATCGGTCTGGTTAACCGAAACTTCCAGTGTCTCACCTGCAGAAAGCACTTCAAAACCAACCGAGGCTTGCAACAGCACACGAATCATTGCCAAAATTCCACCGGGAACGAATCATTCCACTGCACGCACTGCTCTCGAGACTTTGCGACCGGCACGAGCTACACGAACCACGTGAGGAGCTGCCACGCGGAAGCGATTTGCTATTTCTGCGATCACGGATGGAGTACGGAGCAGAAGCTGCTGGACCACGTTCGCGAGGCCCACAAGGACAAGCTGTTCAGCTGCAAGCGATGCTCCAAGACGGAACGGTTGAGGAAAACGCTGAACCGACACGTTCGGTTGGTGCACGGAGTTTTGGTCAGGGAATTTTACTGCGGGCACTGTGAGATGACCTTTGAGGATGTTTCTTCGTTGAGCGAGCACATCCAGGGGAGTCACGCGAACTTGGAGGAAGCTGGACGCGCTTACGAAGAGTTGCTGAACGATTCGCTGTTTCCGAAAGAGGTTGGGCTGGACATGGAACAGGACAGAGAAGAGCAGGAGGAGCATCAGGAAacgtttttgaagcatttcaaTCTGGTTCGGAGTGCAAACTCCGCAGGCAAATCCAAACCCAACCCAAATAAGATGATTCTGGAGGAGTTTCTGGACGAGGCATTTGAAAACGACCAAATTTGGACCAAGTACATTGCAGGAGGTGAAGAATACCTCATCGATAACTACGAATTCTACCTCGATGGACCGTCACAAGCCGCCGCAAGCAATTACAAATGTCCTCGATGTGAGGAAGGATTCAACAAGCAATGTCACTTACATTGCCACTTGGCTGAGCAACACAACATTCGGTGTTTAATTTGCAACGATTGTGGAGCCAACTTCAACCGCATCAACGAGTACAAAAGCCATCGCCAAGAGCACCTGAAGGACAATACTAAATTCAGGGAAAACGTAATTCCCGAAGCCGAGGAAGCCTTGTCCCTGGTGCAGCGAGAGGAGAAAGAATACGTCCTAACGGAACACGAGAAGGGTTACACTTTCACCTGCAAACTGTGCGAACGAACGTTTGCGAAAAAGTGCAACCTTGAAAAGCATCAATGCTCGTTCTACAACGGTCAGCCAAAAGCAACCCCAAACAGCACTCCCTCAACATCGAGCGACAGCCTGTTCTGCACGCTGTGCGACCGCAAGTTCACCTCCATTTCCGGCCTCAAGTACCACCTGAAGCGGCATACCGACGTTAAAGCGTTCCCCTGCTTGTACTGCAACCAAAAGTTCACCGCCAACTCCAACCTGAACGCCCACATCCGGAACGTCCACAGCGAGAGCAAGAACCACGTGTGCCCCCACTGCGAGCTGCGGTTCGCCGGGAAGGACCACCTGACCAAGCACATCCGGTCGCGGCACGAAAAGGATCGCGCCTTTGCGTGCTCGGAATGCTCGAAGAGTTACTTTCAGAAATCTCACCTAAACGACCACGTGGCAGCGGTCCACTCGGGCTACAAGGCGTTCTCGTGCGAGCAGTGCGGCGCTTCGTACAGCGGCAAGGGCTCCCTGCGAAGACACGTGGCCAAAGCGCACAATAAATGCGAATAA
- Protein Sequence
- MCVNGFVCRLCSMESTKSIDLEATSNVGLKKMFDVFMFPKKLQLPHSICEECSNQAQTCYRFFQLIIQYIEANDSTQEPQNDAEETLQTCDVCHSAFTTDLDLERHRKLVHIGLVNRNFQCLTCRKHFKTNRGLQQHTNHCQNSTGNESFHCTHCSRDFATGTSYTNHVRSCHAEAICYFCDHGWSTEQKLLDHVREAHKDKLFSCKRCSKTERLRKTLNRHVRLVHGVLVREFYCGHCEMTFEDVSSLSEHIQGSHANLEEAGRAYEELLNDSLFPKEVGLDMEQDREEQEEHQETFLKHFNLVRSANSAGKSKPNPNKMILEEFLDEAFENDQIWTKYIAGGEEYLIDNYEFYLDGPSQAAASNYKCPRCEEGFNKQCHLHCHLAEQHNIRCLICNDCGANFNRINEYKSHRQEHLKDNTKFRENVIPEAEEALSLVQREEKEYVLTEHEKGYTFTCKLCERTFAKKCNLEKHQCSFYNGQPKATPNSTPSTSSDSLFCTLCDRKFTSISGLKYHLKRHTDVKAFPCLYCNQKFTANSNLNAHIRNVHSESKNHVCPHCELRFAGKDHLTKHIRSRHEKDRAFACSECSKSYFQKSHLNDHVAAVHSGYKAFSCEQCGASYSGKGSLRRHVAKAHNKCE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00401993;
- 90% Identity
- iTF_00401993;
- 80% Identity
- -