Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: -
Assembly: GCA_015732765.1
Location: NC:2285206-2287346[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.019 0.53 10.6 1.7 3 23 164 185 162 185 0.88

2 12 0.0019 0.054 13.7 0.3 2 21 198 217 197 218 0.94

3 12 0.00098 0.028 14.6 0.3 1 23 225 247 225 247 0.98

4 12 0.19 5.5 7.4 1.3 6 23 265 283 258 283 0.87

5 12 0.0064 0.18 12.0 0.3 1 20 299 318 299 320 0.94

6 12 4.2e-05 0.0012 18.9 0.2 2 23 332 353 331 353 0.96

7 12 0.0007 0.02 15.1 3.1 1 23 359 382 359 382 0.97

8 12 2.7e-06 7.8e-05 22.7 3.2 1 23 388 410 388 410 0.96

9 12 5.6e-05 0.0016 18.5 1.8 1 23 416 438 416 438 0.99

10 12 0.044 1.3 9.4 1.6 1 23 444 467 444 467 0.92

11 12 0.0031 0.087 13.1 1.8 1 23 473 496 473 496 0.95

12 12 0.00018 0.0052 16.9 0.9 1 23 504 527 504 527 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.019	0.53	10.6	1.7	3	23	164	185	162	185	0.88
2	12	0.0019	0.054	13.7	0.3	2	21	198	217	197	218	0.94
3	12	0.00098	0.028	14.6	0.3	1	23	225	247	225	247	0.98
4	12	0.19	5.5	7.4	1.3	6	23	265	283	258	283	0.87
5	12	0.0064	0.18	12.0	0.3	1	20	299	318	299	320	0.94
6	12	4.2e-05	0.0012	18.9	0.2	2	23	332	353	331	353	0.96
7	12	0.0007	0.02	15.1	3.1	1	23	359	382	359	382	0.97
8	12	2.7e-06	7.8e-05	22.7	3.2	1	23	388	410	388	410	0.96
9	12	5.6e-05	0.0016	18.5	1.8	1	23	416	438	416	438	0.99
10	12	0.044	1.3	9.4	1.6	1	23	444	467	444	467	0.92
11	12	0.0031	0.087	13.1	1.8	1	23	473	496	473	496	0.95
12	12	0.00018	0.0052	16.9	0.9	1	23	504	527	504	527	0.95

Sequence Information

Coding Sequence: ATGAGTGGAAGTGTTAAAGTTTGTCGAATATGCCTCATGGAATCGGAACCGGGCACGGATATGGTGTCGATTTTTACCGAAAGAGAAGCTTTGGACGAGGTGGTGGCCAACATGATTATCGATTGCTTCAGCGTGCTGGTGTCGGAACAGGACGGATATTCTCCGTGGATGTGTGGACCGTGTTTGACGCGGCTGGAAGGTTGTTACCTGCTAAGGAGGCAGTATGACGAATCATGTAGAAAGGTAGATGAAAGAAATTTGGAAGAGTCTCAAAACGTGGAAGAATTACCTGAGAGTATAATTGAAGAAGAGAGTATAATTGATGAAGAAAGTATAATAGAAGAGGAAATCATAGCCGAAGAAGTCGTCCAGGAGTATAAAACACCAGAAACGCCTTCAGAGTCAGCAGACGAAACTGACAGCGAGCAATCttcatcagaatttcaaaaagacGTTCATTACAAAGTAATTGACGTTGACGGCGTGTGCTGTTGTGAGTGCAATGAAATGTTCTCCGACGAAGCATCGTTGATACAGCACTCCGAGAATGATCACAGACCGGAGTCGACAGAGTTGAAAACTGGAATGCTTCAGTGCGATATTTGCTATGCAATGTTCTCCACCAACGGTAGATTGCAAAGACACACGAAGCGTCGTTATTCGCGAGTTTTGTACGAGTGTTTGGAGTGCCAGGCGATATTTCGATCCAATGCACGACTACAGACCCACTTGATCAAGCACGATCGCAAGAGTAGCCGAGCGGTGAAAGATTACCCTTGTTGCATTCGATGTTGCCCAGAAACCTTCCCGACTCAAGAGCATCTCGTTGAACACGCCCAAGAGTATCATGGACCACTTCGCAGTATCAACAAATCCACACGAGAGTCGGACGATCATGTCTGCCAAGTGTGTCTCAATTCCTTCTCAACGAAAAATGCGTTGATCAAGCATAGACTCGCCAAACAAGACACTCCTCCATCAGTAAAAGGTTTAGTCTGCTCAACCTGTGGAAAGGTCTTCAAAGCTCTGTCCTTGCTGCAAGCTCATGAAAACAAACACAAAGGCATTAATCCATTTCCCTGCAACGAGTGTAGTGAATCCTTCCACTCATACCCAATGCTCCAAAGACACAAACGAAGATTCCACGTGGACAAACATCGCCACCAGTGCCCAAACTGTCCAAAATCCTTCGCGCACAAAAGCCAACTCAAGATCCACCAAGTCTACCACCTGGACCTCAAACCATACAAATGCGAAACCTGCCCAGAAACCTTCCGCCTCAAAAACCAACTAAAAATCCACAACCGACGCCACACCGGAGAACGCCCATTCCGGTGCCAGTACTGCCAGATGGGCTTTTCGCACGGAACGGACCGGAAACGGCACGAAATGGCCGCCCACACGGGGGAGAAACCGCACAAATGTCGCATCTGCAAGAGTGCCTTTGTGCGGCATCAGCAGCTGGTGGCGCACATGGTCAGTGGCCACGGACGGACCCGGGAAGCCCCGTTCCGGTGCGAGTTCTGCAAGCAGGACTTCCGACAATCGGCGGAGCTGGAGCGGCACGAGAACCAGGACCATGGGATTCAGGATGTCGGGACGATTGTGGCGAACGGGGTTGAGATGCAGTACGCGGTGGCTTATGTGTGA
Protein Sequence: MSGSVKVCRICLMESEPGTDMVSIFTEREALDEVVANMIIDCFSVLVSEQDGYSPWMCGPCLTRLEGCYLLRRQYDESCRKVDERNLEESQNVEELPESIIEEESIIDEESIIEEEIIAEEVVQEYKTPETPSESADETDSEQSSSEFQKDVHYKVIDVDGVCCCECNEMFSDEASLIQHSENDHRPESTELKTGMLQCDICYAMFSTNGRLQRHTKRRYSRVLYECLECQAIFRSNARLQTHLIKHDRKSSRAVKDYPCCIRCCPETFPTQEHLVEHAQEYHGPLRSINKSTRESDDHVCQVCLNSFSTKNALIKHRLAKQDTPPSVKGLVCSTCGKVFKALSLLQAHENKHKGINPFPCNECSESFHSYPMLQRHKRRFHVDKHRHQCPNCPKSFAHKSQLKIHQVYHLDLKPYKCETCPETFRLKNQLKIHNRRHTGERPFRCQYCQMGFSHGTDRKRHEMAAHTGEKPHKCRICKSAFVRHQQLVAHMVSGHGRTREAPFRCEFCKQDFRQSAELERHENQDHGIQDVGTIVANGVEMQYAVAYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400890;
90% Identity: iTF_00400890;
80% Identity: -