Cpip011987.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NC:221802068-221803907[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.03 0.93 10.6 1.7 3 23 164 185 162 185 0.88 2 12 0.0011 0.032 15.2 0.2 2 22 198 218 197 218 0.94 3 12 0.0012 0.038 15.0 0.2 1 23 225 247 225 247 0.98 4 12 0.32 9.7 7.4 1.3 6 23 265 283 258 283 0.87 5 12 0.01 0.32 12.0 0.3 1 20 299 318 299 320 0.94 6 12 6.9e-05 0.0021 18.9 0.2 2 23 332 353 331 353 0.96 7 12 0.0011 0.035 15.1 3.1 1 23 359 382 359 382 0.97 8 12 4.4e-06 0.00014 22.7 3.2 1 23 388 410 388 410 0.96 9 12 9.1e-05 0.0028 18.5 1.8 1 23 416 438 416 438 0.99 10 12 0.072 2.2 9.4 1.6 1 23 444 467 444 467 0.92 11 12 0.0052 0.16 13.0 1.2 1 23 473 496 473 496 0.95 12 12 0.00031 0.0095 16.9 2.1 1 23 504 527 504 527 0.92
Sequence Information
- Coding Sequence
- ATGAGTGGAAGTGTTAAAGTTTGTCGAATATGCCTCATGGAATCGGAACCGGGCACGGATATGGTGTCGATTTTTACCGAAAGAGAAGCTTTGGACGAGGTGGTGGCCAACATGATTATCGATTGCTTCAGCGTGCTGGTGTCGGAACAGGACGGATACTCTCCTTGGATGTGTGGACCGTGTTTGACGCGGCTGGAAGATTGTTACCTGCTAAGGAGTCAGTATGTCGAATCATGTAGAAAGGTAGATGAAAGAAATTTGGAAGAGTCTCAAAACGTGGAAGAATTACCTGAGAGTATAATTGTAGAAGAGAGTAAAATCGACGAAGAAAGTATAATAGAAGAGGAAATCATAGCCGAAGAAGTCGTCCAGGAGTATAAAACGCCAGAAACGCCTTCAGAGTCAGCAGACGAAACTGACAGCGAGCAATCttcatcagaatttcaaaaagacGTTCATTACAAAGTAATTGACGTTGACGGCGTGTGCTGTTGTGAGTGCAATGAAATGTTCTCCGACGAAGCATCGTTGATACAGCACTCCGAGAATGATCACAGACCGGAGTCGACAGAGTTGAAAACTGGAACGCTTCAGTGCGATATTTGCTATGCAATGTTCTCCACCAACGGAAGATTGCAAAGACACATCAAGCGTCGTTATTCGCGAGTTTTGTACGAGTGTTTGGAGTGCCAGGCGATATTTCGATCCAATGCACGACTACAGAACCACTTGATCAAGCACGATCGCAAGAGTAGCCGAGCGGTGAAAGATTACCCTTGTTGCATTCGATGTTGCCCAGAAACCTTCCCGACTCAAGAGCATCTCGTTGAACACGCCCAAGAGTATCATGGACCACTTCGCAGCATCAACAAATCCACACGAGAGTCGGACGATCATGTCTGCCAAGTGTGTCTCAATTCCTTCTCAACGAAAAATGCGTTGATCAAGCATAGACTCGCCAAACAAGACACTCCTCCATCAGTAAAAGGTTTAGTTTGCTCGACCTGTGGAAAGGTCTTCAAAGCTCTGTCCTTGCTGCAAGCTCATGAAAACAAACACAAAGGTATTAATCCATTTCCCTGCAATGAATGTAGTGAATCCTTCCACTCATACCCAATGCTCCAAAGACACAAACGAAGATTCCACGTGGACAAACATCGCCACCAGTGCCCAAACTGTCCAAAATCCTTCGCGCACAAAAGCCAACTCAAGATCCACCAAGTCTACCACCTGGACCTTAAACCATACAAATGCGAAACCTGCCCAGAAACCTTCCGCCTCAAAAACCAACTAAAAATCCACAACCGACGCCACACCGGAGAACGCCCATTCCGGTGCCAGTACTGCCAGATGGGCTTTTCCCACGGAACGGACCGGAAACGGCACGAAATGGCCGCCCACACGGGGGAGAAACCGCACAAATGTCGCATCTGCAAGGGTGCCTTCGTGCGGCATCAGCAGCTGGTGGCGCACATGGTCAGTGGCCACGGACGGACCCGGGAAGCGCCCTTCCGGTGCGAGTACTGCAAGCAGGACTTCCGACAGTCGGCGGAGCTGGAGCGGCACGAGCACCAGGACCATGGGATTCAGGACGTCGGGACGATTGTGGCGAACGGGGTTGAGATGCAGTACGCGGTGGCTTATGTGTGA
- Protein Sequence
- MSGSVKVCRICLMESEPGTDMVSIFTEREALDEVVANMIIDCFSVLVSEQDGYSPWMCGPCLTRLEDCYLLRSQYVESCRKVDERNLEESQNVEELPESIIVEESKIDEESIIEEEIIAEEVVQEYKTPETPSESADETDSEQSSSEFQKDVHYKVIDVDGVCCCECNEMFSDEASLIQHSENDHRPESTELKTGTLQCDICYAMFSTNGRLQRHIKRRYSRVLYECLECQAIFRSNARLQNHLIKHDRKSSRAVKDYPCCIRCCPETFPTQEHLVEHAQEYHGPLRSINKSTRESDDHVCQVCLNSFSTKNALIKHRLAKQDTPPSVKGLVCSTCGKVFKALSLLQAHENKHKGINPFPCNECSESFHSYPMLQRHKRRFHVDKHRHQCPNCPKSFAHKSQLKIHQVYHLDLKPYKCETCPETFRLKNQLKIHNRRHTGERPFRCQYCQMGFSHGTDRKRHEMAAHTGEKPHKCRICKGAFVRHQQLVAHMVSGHGRTREAPFRCEYCKQDFRQSAELERHEHQDHGIQDVGTIVANGVEMQYAVAYV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00401987;
- 90% Identity
- iTF_00401987;
- 80% Identity
- -