Cqui004745.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culex quinquefasciatus
Gene Symbol
ZNF512
Assembly
GCA_015732765.1
Location
NC:42300864-42324657[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 38 0.24 6.9 7.1 0.0 3 20 58 76 56 78 0.92
2 38 0.066 1.9 8.9 0.0 3 23 85 106 83 106 0.94
3 38 5.4 1.5e+02 2.8 0.1 1 19 112 133 112 135 0.89
4 38 0.41 12 6.4 0.2 2 15 147 160 147 167 0.79
5 38 1.3 36 4.8 0.1 2 23 173 194 172 194 0.95
6 38 0.014 0.41 10.9 0.8 2 21 237 256 236 257 0.91
7 38 0.13 3.7 8.0 0.0 3 20 282 299 281 301 0.94
8 38 0.00034 0.0096 16.1 1.2 2 23 307 328 306 328 0.97
9 38 5.4 1.6e+02 2.8 0.2 1 20 334 356 334 358 0.84
10 38 0.052 1.5 9.2 0.9 1 20 373 392 373 394 0.86
11 38 0.12 3.4 8.1 0.4 2 23 400 421 399 421 0.97
12 38 3.2 91 3.6 0.1 1 21 427 450 427 451 0.89
13 38 0.0047 0.13 12.5 0.1 2 21 569 588 568 588 0.94
14 38 0.0011 0.031 14.5 0.8 2 23 595 616 595 616 0.97
15 38 3.4 96 3.5 0.1 2 20 663 681 662 683 0.93
16 38 0.26 7.4 7.0 0.5 3 23 690 710 682 710 0.86
17 38 0.8 23 5.5 0.3 1 21 716 736 716 737 0.91
18 38 0.23 6.4 7.2 1.9 3 21 756 774 755 775 0.95
19 38 0.2 5.8 7.3 2.7 2 23 781 802 780 802 0.97
20 38 0.00013 0.0037 17.4 0.2 2 19 847 864 846 866 0.94
21 38 0.12 3.3 8.1 0.1 2 21 917 936 916 937 0.92
22 38 3.1 87 3.6 2.0 2 23 943 963 942 963 0.96
23 38 0.11 3.2 8.2 0.5 1 20 1083 1102 1083 1104 0.89
24 38 9.9 2.8e+02 2.0 0.1 1 19 1111 1132 1111 1134 0.88
25 38 0.53 15 6.0 0.5 3 20 1154 1171 1153 1173 0.93
26 38 0.36 10 6.5 0.4 2 23 1185 1206 1184 1206 0.94
27 38 4.8 1.4e+02 3.0 0.1 3 19 1245 1261 1243 1264 0.89
28 38 0.064 1.8 8.9 0.2 1 23 1270 1292 1270 1292 0.96
29 38 0.00065 0.019 15.2 0.2 1 19 1317 1335 1317 1335 0.98
30 38 0.53 15 6.0 0.1 1 23 1343 1365 1343 1365 0.95
31 38 0.36 10 6.6 0.3 1 19 1371 1391 1371 1394 0.92
32 38 0.023 0.66 10.3 0.5 1 23 1419 1441 1419 1441 0.96
33 38 3.6 1e+02 3.4 0.2 1 19 1447 1468 1447 1471 0.84
34 38 0.00016 0.0047 17.1 0.2 3 21 1489 1507 1487 1508 0.93
35 38 9.1 2.6e+02 2.1 0.0 2 23 1521 1542 1520 1542 0.93
36 38 4.5 1.3e+02 3.1 0.3 1 23 1606 1628 1606 1628 0.97
37 38 0.054 1.5 9.1 4.8 1 23 1639 1661 1639 1661 0.97
38 38 4.2 1.2e+02 3.2 0.8 2 21 1671 1690 1670 1692 0.92

Sequence Information

Coding Sequence
ATGGACAACGTGCCCGGCACCTCGTCCGGGATGGAACCAGACCCCCCCACCTCCACGCTGCTGGCACCGGAACACATCAAGGTTGAGGCCCCGCTGGACATTCCGCCGGAACGGGTCGTCGCCCCAGAACCACCGCGCTCGGTTCGCGCCAAACCGATTCGTTCGTTCGGGTGTGATCGCGGCTGCGGCAAGAGTTTCTTCGCGGAGGCCGCCCTCGTGCGGCATCAGGCCAGCTGCCGAACCGAGATCGCGTGCCCCGAGTGTGGCCTGCTGCTGAAATCGCCCCGGGGGTTGAGGCTGCACATGGAGAACAGGCACAAGGATGTGAAACCGTACGAGTGTCGCGTCAAGACCGGATGTCCGGAAAGGTTTACCAGAATGCAAGACCGGCGTGCTCACGAAGTTGTTTGTGGAAAAGGGGCGAAAGTGAAGGAGAGGCGGTGTTCGGTTTGTGATAAGTCGTTTCCAACCATGACGATGCGGGTTGTTCACGAGTCCAAGTGTGGTCTGACCACGCGGTGTCAGATTTGTGGAATTACGACGGAATCCGTTCTAGGCATGGTTTATCACATGAACAAGCACAAAGGGCTTGCGCCGTTTCCGTGCCGCAAGGGAGGTGGATGTGGTGAAAGGTTTCCCGGGCCGGAAGCTCGTAACTCTCACGAAGCAAAGTGCAACGAGACGGGGCAGAGCGTGAGCGAACAACTTCCGTGTTTGAACTGCGGGGAAAAGTTTGCCAACCATGCCCACCTGTTGAAACACTTTAAATTGTGCCAGTTTGAGCTGAAGGTTGGCTCCGGTCAAGCTGAGGCGCTAAAGCAGGAACCAGAGGTTGAAAGCTTGTGCCAAGGATGTGGCCAGCGGTTTCCATCTGCCGGGGCACTCGGAATCCATCAGATTCAATGCAAACTCGCGACGACGTGCACAATTTGCAGCAAGGAATTCAAAACCAACCTCGGTTTGACCTATCATATGAACTCGCACTACGGACTGCTTCCGTTCGAGTGTCGAACTACGCCCGGTTGCCCGTTACGGTTCTCAAATCCATACCGGCGCCTACGGCATGAACAGAGATGCAGTGCAGAAATGGGCCCAATCAACACGGCGGAAGTGCCATTCCGGTGCGAAACCTGCAAAAAGGTGTTTTCAACAGCCCAGAAGCGAGACTCGCACCTAATGTTCTGCGGCCTGACGACGACCTGCGCCATTTGCGGGAACACAACGCGCTCTACCCAAAGCATGGCTTATCACATGAACATGCATAGAGgtGTCAAACCGTATGAGTGCCGTGAGGGAACCGGCTGTGGCCTTCGATTCTACTCACCCTGGGCTCGCAACACCCACAAAAAGGTGTGCAAGAAGAACAACAAGAAGATAATTGATGTCGGGACTCCAGTCGTCAGTTCGGTGAAGATGGAAGCTTTCCAGAACCAGACGAACTCAGAAGATCTTTCTTCGGTAAACATCAAGCAGGAAGTGGAGCTTAATGATGCGCAGATGGAAACGTCCCAGAACCAGACCATTGCGGTTGCGCCTCTTTCTGTACAAATCAAGCAGGAAGTGGAGCCTGATGATGTGCAGATCGAAGCTCAGACGGAAGCGTCCCAGAATCAGACGATCTCGGAGGCGCCTTCTACGGCATACATCAAGCATGAAATCGAGCCGGTTGATGAGCAGAAGGAAGCTCAGAAATCGAAAGTTAAGCAATGTCCTGGATGTAACAAAGCCTTTGCGTCCGAGGCCTTCCTAACCGAGCATCGGAAGTGCTGCGTCGCTTCGAGAGAATGCTGGATCTGCGGGAAAAAGTTTGCCACGAGGGAATCGTTGAAATTCCACCTCAACAAACACAACGGAGTCAATCCGTACCAGTGTCGTGTCACGCCCGGTTGCCAGGCCCGGTTCTACAATTCCATCAAGCGCAATTATCACGAGGCCGACTGTGCCCGTCTGGGTGGCAGCGATGAGTCGGGTCAACCGAAGTCACTCGAATGTCCCAGCTGCAGCAGCAAGTTCGCTTCCACAGTGGCTCTAAGCCAACACCAGGTGAGGTGCAACGTCCCAACGGTTTGCATAATCTGCGGCCGCACGATGGCGTCCTTTACTTCGCTGCAATACCACATGAACAAACACAAAGGACTCAAGCCTTACCACTGTAGCAACTGTCCCGCCAAGTATTCCAACCCCGGAGCACGCAATCAACACGAGCAGCGCTGTCTCCGGAGGAAAAACCCCGCCGGGAAGCTCAAACCAAACACGCTGACGCTGTGCGATCGCTGTGGACAGGACTGCCGGACGGTGCGACAGCTACGAAAGCATCAGAACAACTGCAGCGTTAGCAAAACGTGCGGCATTTGCAATCGAATCCTTCACTCGCACAATGCCCTGCGAGCTCACCTGAACCGACACAACAACGTCAAGCCGTACCAGTGCCGCGAGTCGACCCAATGTGGAGCCCGCTTTCATGCCTCGGGTCAGCGGAACACGCACGAACGGGGCTGTCCGTTCCGAGCCAAAACTAGCGACGGTTCCGGGCAGATTACGTGTGAGGGTTGTGGGAAAAGCTTCACCAAAGCTGCTCACTTGCAAAGTCATGAGACGCTATGTGTTGGCCGGCAGTTCGGCGCTGACTCGGGGGAGGATTTGGAAGAGCTTCCGGAAGACACGAACTTGCCAGTGGGGGAACAGGAGTGCGAATCAAAACCGATAGAGAACCATGAAGATCCTGCACCGGCAACCTGGAGCACTACGAGCTGTGTGGGCTGCGGAGAGGACTTTGCATCCACGGAACTGCTGCAGAGTCATAAGCAGAGTTGTGGCACGAAGAAGACCTGCACCGTTTGCAGGAAGTCTGTCGTGATTGACCACTTCGAGTATCACATGAACAGGCATTCCGGCGTGAACCCGTACCGCTGCCGCGTACGGGATGGTTGTCCGGCCGCATTCCACAATCCGTGGTTGCGCAACAAGCACGAACGGATATGCCGCGGCGGCCCGGAGAAGAAAACGGATCCCGAGGAGGGCAAGTGTCGCCGCTGTGGCAAGGAGCTGGACCGGCAAACTATGCTGCACGTTTGCGAGGGATTCCAGATGGAGCAGGAGGAAAAGGTGATCAAGTGGAGTTACACGAAGGAGGTCGAGCCGAGTTCTGTGAAGGTGGAGAGTGTTGATGTTAAGGTTGAGGAGAAGAAATCTGTAGACGAGGAAGACCTGTTGGAGGTTACGTTTGAACAGCCGGTAGACCTTAGGTTCTTTTGCGAAGCCTGTGGCAAAGAGTTCAACTCGAGCGAACTTCGGAACAAGCACACTTCAAGCTGTGACAAAGCGTTGCCATATCAGTGCCGACTGTCGGCCGAGTGTCCGGAGCGGTTTGCGAATGCCCAGTTCCGTCGGAACCACGAAGTCATCTGTGGCAAATCGCGACGACTTGGGGGCAAGTCGGCCAAGGTTGAACTGGTGGCTTGTCGGAGCTGTGGAAAGGTGTGCAACGGCAAGCAGTTGCTACGGGTTCACAGAGAGCTTTGCGGCCCGGAAGTGGAGCTTCCCGCAGAATTGAGGTGCACGGTTTGTTCGGAGGTTTGCGATAGTGTGGAGAAACTGCAGGAGCATTTGGATGAGCATAATCGAGAGAAATTTCTCAAATGTCGCGCATCGGCAAACTGTTTGGAATCTTTCAAGCAACAAAGAACCAGAATCGATCACGAGCTGGAATGCACCGCCGCAGGCCAGACCATCtgttcaaaatgtttcaaactcTTGCCGAACCCCGACTCCCTCGAAGATCACGAAGACTCCTGCCAAGGAGACGAGTTTATCTGCCGACTTTGCGACGCTACTTACAGCGATGTCCTCGGCCTGCGGAAGCACCTGCTGAACCACGAAAATCCCGGCCGGCACGCGAGATGGTGGGAAAAGCCAACCCGCAATCCGGTGATGCCGAACCGGCAACGGTACAGCTGTGAAAATTGTGGCCAGGAATTCGTCACTCAGGAAGAGCTGCAAAAACATCCCGCCCTTTGCAAGTTCGTTTACCGCTGCGCCGAGTGTCCGGCGGCCTTTGCGAAGCCGCTTTcgttaaaatttcacgaaaatatGCACAGTGGCGCTAAACCGTTCGAGTGTCGCAAGGAGGGCTGTACAAAGGGATTCGCGAATCCTTATCATCGGCGGGCCCACGAAGAGCTGTGTGGTACCAGCAAGGCGGAGGAACATCTGAAGAAGGTCGAGCAGGGCGGGACGTCGACTGCGGCGAAGGTGTTTCCCTGTCCGCATTGTACGGCCACGTTCAAAGCGGTCAACGAGTTGAAGTATCACGTGAATGAGCATAAAGCAAACGAAATGTTCCCGTGCCGGCAATCCGACGACTGCCAGGAAACCTTCACCACTCGCGGCTTCCGCCTCAAGCACGAGGCCATCTGTGGCAAACTGGCCGTGCCCAAGCAGCCCCGCAAGGTCGAACTGATTGCGTGCAAGGACTGCGGCAAGGTGTTTAGCAATTTGCAGTATCTGCGAATTCACAAGCAAAAGTGCGCCGGAAGTGAGGAGGGACCGCCGTCGAATCTCAAGTGTACGCTGTGTACGGTTATCTCGCCAGATGTGGAAGCACTGCAGGAGCATCTGGACGGGCACAACCGGGAGAAACCTTTTCAGTGTCGGATTTCGAAGGCGTGCAGTGAATCGTACATTAACGAACGTCAGCGAGGCAATCACGAGCTGGTGTGTAACGCCGACGGGCAGGTAATTTGCCAGCGATGTTTCAAGCTGTGTTCATGCTTGGAAACGCTGAAGAGCCACGAGAAAATTTGCCGCGGGACGGAGTTTCCGTGCAGACTTTGTGAGGTTGTCCTGCGCACTCGGAACTCACAGCTGGTGCACTATCTTCGGCACGATAACGAGAAAAGGCAATCGAACCGAATGCATGTCTGTCCCAGCTGTGATAAGCAGTTCCATAAGAGGACCAATTTCCTCTTGCATTTGAAGGAGCACAACATCGACCCAAGTGATTTGAAACTCAAGTGTGAAATCTGCGCTGCTACGTTCAAAGCGATGAAAACAATGGAAATACATATGAATTGCCATAAAGGCATCAAATCGTACAAGTGTCGCTACCAGGGCTGTGAGGAGGCTTTCTTCCAGTCAACAGCACGGGAGGTCCACGAGCAGAACTGCACTAAGGTGTCCCTAACGTGCGATATTTGCGAACTTAAGCTGGTCTGTATGCGTGATTACCAGCTGCACATCAGGTCGCACGATGCGGCGAACAGCTTGGAAGGGCTGTAA
Protein Sequence
MDNVPGTSSGMEPDPPTSTLLAPEHIKVEAPLDIPPERVVAPEPPRSVRAKPIRSFGCDRGCGKSFFAEAALVRHQASCRTEIACPECGLLLKSPRGLRLHMENRHKDVKPYECRVKTGCPERFTRMQDRRAHEVVCGKGAKVKERRCSVCDKSFPTMTMRVVHESKCGLTTRCQICGITTESVLGMVYHMNKHKGLAPFPCRKGGGCGERFPGPEARNSHEAKCNETGQSVSEQLPCLNCGEKFANHAHLLKHFKLCQFELKVGSGQAEALKQEPEVESLCQGCGQRFPSAGALGIHQIQCKLATTCTICSKEFKTNLGLTYHMNSHYGLLPFECRTTPGCPLRFSNPYRRLRHEQRCSAEMGPINTAEVPFRCETCKKVFSTAQKRDSHLMFCGLTTTCAICGNTTRSTQSMAYHMNMHRGVKPYECREGTGCGLRFYSPWARNTHKKVCKKNNKKIIDVGTPVVSSVKMEAFQNQTNSEDLSSVNIKQEVELNDAQMETSQNQTIAVAPLSVQIKQEVEPDDVQIEAQTEASQNQTISEAPSTAYIKHEIEPVDEQKEAQKSKVKQCPGCNKAFASEAFLTEHRKCCVASRECWICGKKFATRESLKFHLNKHNGVNPYQCRVTPGCQARFYNSIKRNYHEADCARLGGSDESGQPKSLECPSCSSKFASTVALSQHQVRCNVPTVCIICGRTMASFTSLQYHMNKHKGLKPYHCSNCPAKYSNPGARNQHEQRCLRRKNPAGKLKPNTLTLCDRCGQDCRTVRQLRKHQNNCSVSKTCGICNRILHSHNALRAHLNRHNNVKPYQCRESTQCGARFHASGQRNTHERGCPFRAKTSDGSGQITCEGCGKSFTKAAHLQSHETLCVGRQFGADSGEDLEELPEDTNLPVGEQECESKPIENHEDPAPATWSTTSCVGCGEDFASTELLQSHKQSCGTKKTCTVCRKSVVIDHFEYHMNRHSGVNPYRCRVRDGCPAAFHNPWLRNKHERICRGGPEKKTDPEEGKCRRCGKELDRQTMLHVCEGFQMEQEEKVIKWSYTKEVEPSSVKVESVDVKVEEKKSVDEEDLLEVTFEQPVDLRFFCEACGKEFNSSELRNKHTSSCDKALPYQCRLSAECPERFANAQFRRNHEVICGKSRRLGGKSAKVELVACRSCGKVCNGKQLLRVHRELCGPEVELPAELRCTVCSEVCDSVEKLQEHLDEHNREKFLKCRASANCLESFKQQRTRIDHELECTAAGQTICSKCFKLLPNPDSLEDHEDSCQGDEFICRLCDATYSDVLGLRKHLLNHENPGRHARWWEKPTRNPVMPNRQRYSCENCGQEFVTQEELQKHPALCKFVYRCAECPAAFAKPLSLKFHENMHSGAKPFECRKEGCTKGFANPYHRRAHEELCGTSKAEEHLKKVEQGGTSTAAKVFPCPHCTATFKAVNELKYHVNEHKANEMFPCRQSDDCQETFTTRGFRLKHEAICGKLAVPKQPRKVELIACKDCGKVFSNLQYLRIHKQKCAGSEEGPPSNLKCTLCTVISPDVEALQEHLDGHNREKPFQCRISKACSESYINERQRGNHELVCNADGQVICQRCFKLCSCLETLKSHEKICRGTEFPCRLCEVVLRTRNSQLVHYLRHDNEKRQSNRMHVCPSCDKQFHKRTNFLLHLKEHNIDPSDLKLKCEICAATFKAMKTMEIHMNCHKGIKSYKCRYQGCEEAFFQSTAREVHEQNCTKVSLTCDICELKLVCMRDYQLHIRSHDAANSLEGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00400889;
90% Identity
iTF_00400889;
80% Identity
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