Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:180911277-180928559[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 35 0.39 12 7.1 0.0 3 20 59 77 57 79 0.92

2 35 0.11 3.3 8.9 0.0 3 23 86 107 84 107 0.94

3 35 8.8 2.7e+02 2.8 0.1 1 19 113 134 113 136 0.89

4 35 0.67 21 6.4 0.2 2 15 148 161 148 168 0.79

5 35 2.1 64 4.8 0.1 2 23 174 195 173 195 0.95

6 35 0.023 0.72 10.9 0.8 2 21 238 257 237 258 0.91

7 35 0.21 6.4 7.9 0.0 3 20 283 300 282 302 0.94

8 35 0.00055 0.017 16.1 1.2 2 23 308 329 307 329 0.97

9 35 0.029 0.9 10.6 0.3 1 21 374 394 374 395 0.87

10 35 0.19 6 8.1 0.4 2 23 401 422 400 422 0.97

11 35 5.2 1.6e+02 3.6 0.1 1 21 428 451 428 452 0.89

12 35 0.022 0.66 11.1 0.3 2 21 570 589 569 589 0.94

13 35 0.061 1.9 9.6 0.7 2 23 596 617 596 617 0.96

14 35 5.5 1.7e+02 3.5 0.1 2 20 664 682 663 684 0.93

15 35 0.42 13 7.0 0.5 3 23 691 711 683 711 0.86

16 35 1.3 40 5.5 0.3 1 21 717 737 717 738 0.91

17 35 0.37 11 7.2 1.9 3 21 757 775 756 776 0.95

18 35 0.11 3.5 8.8 2.7 2 23 782 803 781 803 0.97

19 35 0.00034 0.01 16.7 0.2 2 19 848 865 847 867 0.94

20 35 1.3 38 5.5 0.1 2 21 918 937 917 938 0.91

21 35 0.18 5.5 8.2 0.5 1 20 1084 1103 1084 1105 0.89

22 35 5.7 1.7e+02 3.4 0.1 1 19 1112 1133 1112 1135 0.92

23 35 0.25 7.8 7.7 0.5 3 20 1155 1172 1154 1174 0.94

24 35 0.51 16 6.7 0.1 2 23 1186 1207 1185 1207 0.94

25 35 7.9 2.4e+02 3.0 0.1 3 19 1246 1262 1244 1265 0.89

26 35 0.086 2.6 9.2 0.2 1 23 1271 1293 1271 1293 0.97

27 35 0.0011 0.032 15.2 0.2 1 19 1318 1336 1318 1336 0.98

28 35 1.4 43 5.4 0.1 1 23 1344 1366 1344 1366 0.94

29 35 1.8 56 5.0 0.3 1 19 1372 1392 1372 1395 0.92

30 35 0.038 1.2 10.3 0.5 1 23 1420 1442 1420 1442 0.96

31 35 5.9 1.8e+02 3.4 0.2 1 19 1448 1469 1448 1472 0.84

32 35 0.00027 0.0082 17.1 0.2 3 21 1490 1508 1488 1509 0.93

33 35 7.3 2.2e+02 3.1 0.3 1 23 1607 1629 1607 1629 0.97

34 35 0.088 2.7 9.1 4.8 1 23 1640 1662 1640 1662 0.97

35 35 6.9 2.1e+02 3.2 0.8 2 21 1672 1691 1671 1693 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	35	0.39	12	7.1	0.0	3	20	59	77	57	79	0.92
2	35	0.11	3.3	8.9	0.0	3	23	86	107	84	107	0.94
3	35	8.8	2.7e+02	2.8	0.1	1	19	113	134	113	136	0.89
4	35	0.67	21	6.4	0.2	2	15	148	161	148	168	0.79
5	35	2.1	64	4.8	0.1	2	23	174	195	173	195	0.95
6	35	0.023	0.72	10.9	0.8	2	21	238	257	237	258	0.91
7	35	0.21	6.4	7.9	0.0	3	20	283	300	282	302	0.94
8	35	0.00055	0.017	16.1	1.2	2	23	308	329	307	329	0.97
9	35	0.029	0.9	10.6	0.3	1	21	374	394	374	395	0.87
10	35	0.19	6	8.1	0.4	2	23	401	422	400	422	0.97
11	35	5.2	1.6e+02	3.6	0.1	1	21	428	451	428	452	0.89
12	35	0.022	0.66	11.1	0.3	2	21	570	589	569	589	0.94
13	35	0.061	1.9	9.6	0.7	2	23	596	617	596	617	0.96
14	35	5.5	1.7e+02	3.5	0.1	2	20	664	682	663	684	0.93
15	35	0.42	13	7.0	0.5	3	23	691	711	683	711	0.86
16	35	1.3	40	5.5	0.3	1	21	717	737	717	738	0.91
17	35	0.37	11	7.2	1.9	3	21	757	775	756	776	0.95
18	35	0.11	3.5	8.8	2.7	2	23	782	803	781	803	0.97
19	35	0.00034	0.01	16.7	0.2	2	19	848	865	847	867	0.94
20	35	1.3	38	5.5	0.1	2	21	918	937	917	938	0.91
21	35	0.18	5.5	8.2	0.5	1	20	1084	1103	1084	1105	0.89
22	35	5.7	1.7e+02	3.4	0.1	1	19	1112	1133	1112	1135	0.92
23	35	0.25	7.8	7.7	0.5	3	20	1155	1172	1154	1174	0.94
24	35	0.51	16	6.7	0.1	2	23	1186	1207	1185	1207	0.94
25	35	7.9	2.4e+02	3.0	0.1	3	19	1246	1262	1244	1265	0.89
26	35	0.086	2.6	9.2	0.2	1	23	1271	1293	1271	1293	0.97
27	35	0.0011	0.032	15.2	0.2	1	19	1318	1336	1318	1336	0.98
28	35	1.4	43	5.4	0.1	1	23	1344	1366	1344	1366	0.94
29	35	1.8	56	5.0	0.3	1	19	1372	1392	1372	1395	0.92
30	35	0.038	1.2	10.3	0.5	1	23	1420	1442	1420	1442	0.96
31	35	5.9	1.8e+02	3.4	0.2	1	19	1448	1469	1448	1472	0.84
32	35	0.00027	0.0082	17.1	0.2	3	21	1490	1508	1488	1509	0.93
33	35	7.3	2.2e+02	3.1	0.3	1	23	1607	1629	1607	1629	0.97
34	35	0.088	2.7	9.1	4.8	1	23	1640	1662	1640	1662	0.97
35	35	6.9	2.1e+02	3.2	0.8	2	21	1672	1691	1671	1693	0.92

Sequence Information

Coding Sequence: ATGGACAACGTGCCCGGCACCTCGTCCGGGATGGAACCAGACCCCTCCACCTCGATGCTGCTGGCACCGGAAGACATCAAGGAGGAAGTCCCGCTGGACATTCCACCGGAACGGGTGGTCGTTGCCCCAGAACCACCGCGCTCGGTTCGCGCCAAACCGATTCGTTCGTTCGGGTGTGATCGCGGCTGCGGCAAGAGTTTCTTCGCGGAGGCCGCCCTCGTGCGGCATCAGGCCAGCTGCCGCACCGAGATCGCGTGCCCCGAGTGTGGCCTGCTGCTGAAATCGCCCCGGGGGTTGAGGCTGCACATGGAGAACAGGCACAAGGGTGTTCAACCGTACGAGTGTCGCGTCAAGACCGGATGTCCGGAAAGGTTTACCAGAATGCAAGATCGGCGTGCGCACGAAGTTGTTTGTGGAAAAGGGGCGAAAGTGAAGGAGAGGCGGTGTTCGGTTTGTGATAAGTCGTTTCCAACCATGACGATGCGGGTTGTTCACGAGTCCAAGTGTGGCCTGACCACGCGGTGTCAGATTTGTGGAATTACGACGGAATCCGTCCTAGGCATGGTTTATCACATGAACAAGCACAAAGGGCTTGCGCCGTTTCCGTGCCGCAAGGGAGGTGGGTGTGGTGAAAGGTTTCCCGGTCCCGAAGCTCGTAACTCTCACGAAGCAAAGTGCAACGAGACGGGACAGAGCGTGAGCGAAGAACTTCCGTGTTTGAACTGCGGGGAAAAGTTTGCCAACCATGCCCACCTCTTGAAACACTTTAAATTGTGCCAGTTTGAGTTGAAGGTTGATTCCGGCCAAGCTGAGGCGCTAAAGCAAGAACCAGAGGTTGAAAGCTTGTGCCAAGGATGTGGCCAGCGGTTTCCATCTGCCGGGGCACTCGGAATCCATCAGATTCAATGCAAACTCGCGACGACGTGCACAATTTGCAGCAAGGAATTCAAAACCAACCTCGGTTTGACCTATCATATGAACTCGCACTACGGACTGCTTCCGTTCGAGTGTCGCACTACGCCCGGATGCCCCTTGCGGTTCTCAAATCCATACCGGCGCTTACGGCATGAACAGCAATGCAATGCGGAAATGGGCCCAATCAACACGGCGGAAGAGCCATTCCGGTGCGAAACCTGCAATAAGGTTTTTTCAACAGCCCAGAAGCGAGACTCGCACCTAATGATCTGCGGCCTGACGACGACCTGCGCCATTTGCGGAAACACAACGCGTTCTACCCAAAGCATGGCTTATCACATGAACATGCATAGAGgtATCAAACCGTATGAGTGCCGCGAGGGCACCGGCTGTGGCCTTCGATTCTACTCACCCTGGGCTCGCAACACCCACAAAAAAGTGTGCAAGAAGAACAACAAGAAGATAATTGATGTCGAGACTCCAGTCGTCAGTTCGGTGAAGATGGAAGCGTCCCAGAACCAGACGAACTCAGAAGATCTTTCTTTGGTGAACATCAAGCAGGAAGTGGAGCTTGATGATGCGCAGATGGAAACGTCCCAGAACCAGACCAATGGGGAGGAGCCTTTTTCGGTGCAAATCAAGCAGGAAGTGGAGCCTGATGATGTGCAGATCGAAGCTCAGACGGAAGCGTCCCAGAATCAGACGATCTCGGAGGCGCCTTCTTCGGCGAACATCAAGCCTGAAATCGAGCCGGTTGATGAGCAGAAGGAAGCTCAGAAATCGGAAGTTAAGCGATGTACTGGATGTAACAAGGCCTTTGCGTCCGAGGCCTTCCTTACCGAGCATCGGAAGTGCTGCGTCGCTTCGAGAGAATGCTGGATCTGCGCGAAAAAGTTTGCCACGAGGGAATCGTTGAAATTCCACCTCAACAAACACAACGGCGTCAATCCGTACCAGTGTCGTGTCACGCCCGGTTGCCAGGCCCGGTTCTACAATTCCATCAAGCGTAATTACCACGAGACCGACTGTGCCCGTCTGGGTGGCAGCGATGAGTCGGGTCAACCGAAGTCACTCGAATGTCCCAGCTGCAGCAGCAAGTTCGCTTCCACAGTGGCTCTAAGCCAACACCAGGTGAGGTGCAACGTCCCAACGGTTTGCATAATCTGCGGCCGCACGATGGCGTCCTTTACTTCACTGCAATACCACATGAACAAACACAAAGGACTCAAGCCCTACCACTGTAGCAACTGTCCCGCCAAGTATTCCAACCCCGGAGCGCGCAACCAACACGAGCAGCGCTGTCTCCGGAGGAAAAACCCCGCCGGAAAGCTCAAAGCAAACACGCTGACGCTGTGCGATCGCTGTGGACAGGACTGCCGGACGGTGCGACAGCTTCGAAAGCACCAGAACAACTGCAACGTTAGCAAAACGTGCGGAATTTGCAATCGAGTCCTGCACTCGCACAATGCCCTGCGAGCTCACCTGAACCGACACAACAACGTCAAGCCGTACCAGTGTCGAGAGTCCGTTCAGTGTGGAGCCCGCTTTCATGCCTCGGGTCAGCGGAACACGCACGAACGGGGCTGCCCATTCCGAGCCAAAACTAGCGACGGTTCCGGGCAGATTACGTGTGAGGGTTGTGGGAAAAGCTTCACCAAAGCTGTTCACTTGCAAAGTCATGAGACGCTTTGTGTTGGCCGGCAGTTCGGCGCTGATTCGGGGGAGGATTTGGAAGAGCTTCCGGAAGACACGAACTTGCCAGTGGGGGAACAGGAGTGCGAATCAAAACCGATAGAGAACCATGAAGATCCTGCACCGGCAACCTGGAGCACTACGAGCTGTGTGGGCTGCGGAGAGGACTTTGCATCCACGGAACTGATGCAGAGTCATAAGCAGAGTTGTGGCACGAAGAAGACCTGCACCGTTTGCAGGAAGTCTGTCGTGATTGACCACTTCGAGTTTCACATGAACAGGCATTCCGGTGTGAACCCGTACAGCTGCCGCGTACGGGACGACTGTCCGGCCGCATTCCACAATCCGTGGTTGCGCAACAAGCACGAACGGATATGTCGCGGCGGCCCCGAGAAGAAAACGGATCCCGAGGATGGCAAGTGTCGCCGCTGCGGCAAAGAGCTGGACCGGCAAACTATGCTACACGTTTGCGAGGGATTCCAGATGGAGCAGGAGGAAAAGGTGATCAAGTGGAGTTACATGAAGGAGGTCGAGCCGAGCTCAGTGAAGGTGGAGAGCGTTGATGTTAAGGTTGAGGAGAAAAAACCTGTAGACGAGGAAGACCTGTTGGAGGTTACGTTTGAACAGCCGGTAGACCTTAGGTTCTTCTGCGAAGCCTGTGGCAAAGAGTTCAACTCGAGCGAACTTCGGAACAAGCACACTTCAAGCTGTGACAAAGCGTTGCCATATCAGTGCCGACTGTCGGCCGAGTGTCCGGAGCGGTTTGCGAATGCCCAGTACCGTCGGAACCACGAAGTCATCTGTGGCAAATCGAGGAGACTTGGGGGCAAGTCGGTCAAGGTTGAACTGGTGGCTTGTCGGAACTGCGGAAAAGTGTGCAACGGCAAGCAGTTGCTACGCGTTCACAGAGAACTTTGCGGCCCGGAAGTGGAGCTTCCCGCAGAATTGAGGTGTACGGTTTGTTCGGAGGTTAGCGATAGTGTGGAGAAACTGCAGAAGCATTTGGATGAGCATAATCGAGAGAAACTTCTAAAATGTCGCGCATCGGCAAACTGTTTGGAATCTTTCAAGCAACAAAGAACCAGAATCGATCACGAGCTGGAATGCACCGCCGCAGGTCAGACCATCtgttcaaaatgtttcaaactcTTGCCGAACCCCGACTCCCTCGAAGACCACGAAGACTCCTGCCAAGGAGACGAGTTCATGTGCCGACTTTGCGACGCAACTTACAGCGATGTCCTCGGCCTGCGGAAGCACCTGCTGAACCACGAAAATCCCGGCCAGCACGCAAGATGGTGGGAAAAGCCAACCCGCAATCCGGTGACGCCGAACCGGCAACGGTACAGCTGTGAAAATTGTGGCCAGGAATTCGTCACTCAGGAAGAGCTGCAAAAACATCCCGCCCTTTGCAAGTTCATTTACCGCTGCGCCGAGTGTCCGGCGGCCTTTGCGAAGGCGCTTTcgttaaaatttcacgaaaatatGCACAGTGGCGCTAAACCGTTCGAGTGTCGCAAGGAGGGCTGTACAAAGGGGTTCGGGAATCCTTATCATCGGCGGGCCCACGAAGAGCTGTGTGGTACCAGCAAGGCGGAGGAACATCTGAAGAAGGTCGAGCAGGGCGGGACGTCGACTGCGGCGAAGATGTTTCCCTGTCCGCATTGTACGGCCACGTTCAAGGCGGTCAACGAGTTGAAGTATCACGTGAATGAGCATAAAGcaaacGAAATGTTCCCGTGCCGGCAATCCGACGACTGCCAGGAAACCTTCACCACTCGCGGCTTCCGCCTCAAGCACGAGGCCATCTGTGGCAAACTGGCCGCGCCCAAGCAGCCCCGCAAGGTGGAACTGATTGCGTGCAAGGACTGCGGCAAGGTGTTTAGCAATTTGCAGTATCTGCGAATTCACAAGCAAAAGTGCGCCGGAAGTGAGGAGGGACCGCCGTCGAATCTCAAGTGTACGCTGTGTACGGTTATCTCGCCGGATGTGGAAGCACTGCAGGAGCATCTGGACGGGCACAACCGGGAGAAACCTTTTCAGTGTCGAATTTCGAAGGCGTGCAGTGAATCGTACATTAACGAACGTCAGCGAGGCAATCACGAGCTGGTGTGTAACGCCGATGGGCAAGTAATTTGCCAGCGATGTTTCAAGCTGTGTCCATGCTTGGAAACGCTGAAGAGCCACGAGAAAATCTGCCGAGGGACGGAGTTCCCGTGCAGACTTTGTGAGGTCGTCCTGCGCACTCGGAACTCACAGCTGGTGCACTATCTTCGGCACGATAACGAGAAAAAGCAATCGAACCGAATGCATGTCTGTCCCAGCTGTGATAAGCAGTTCCATAAGAGGACCAATTTCCTCTTGCATTTGAAGGAGCACAACATCGACCCAAGTGATTTGAAACTCAAGTGTGAAATCTGCGCTGCTACGTTCAAAGCGATGAAAACAATGGAAATCCATATGAATTGCCACAAAGGCATCAAATCGTACAAGTGTCGCTACCAGGGCTGTGAGGAGGCTTTCTTCCAGTCAGCAGCACGGGAGGTCCACGAGCAGAACTGCACAAAGGTGTCCCTAACGTGCGATATCTGCGAACTTAAGCTGGTCTGTATGCGGGATTATCAGCTGCACATCAGGTCGCACGATGCGGCGAACAGCTTGGAAGGGATGTAA
Protein Sequence: MDNVPGTSSGMEPDPSTSMLLAPEDIKEEVPLDIPPERVVVAPEPPRSVRAKPIRSFGCDRGCGKSFFAEAALVRHQASCRTEIACPECGLLLKSPRGLRLHMENRHKGVQPYECRVKTGCPERFTRMQDRRAHEVVCGKGAKVKERRCSVCDKSFPTMTMRVVHESKCGLTTRCQICGITTESVLGMVYHMNKHKGLAPFPCRKGGGCGERFPGPEARNSHEAKCNETGQSVSEELPCLNCGEKFANHAHLLKHFKLCQFELKVDSGQAEALKQEPEVESLCQGCGQRFPSAGALGIHQIQCKLATTCTICSKEFKTNLGLTYHMNSHYGLLPFECRTTPGCPLRFSNPYRRLRHEQQCNAEMGPINTAEEPFRCETCNKVFSTAQKRDSHLMICGLTTTCAICGNTTRSTQSMAYHMNMHRGIKPYECREGTGCGLRFYSPWARNTHKKVCKKNNKKIIDVETPVVSSVKMEASQNQTNSEDLSLVNIKQEVELDDAQMETSQNQTNGEEPFSVQIKQEVEPDDVQIEAQTEASQNQTISEAPSSANIKPEIEPVDEQKEAQKSEVKRCTGCNKAFASEAFLTEHRKCCVASRECWICAKKFATRESLKFHLNKHNGVNPYQCRVTPGCQARFYNSIKRNYHETDCARLGGSDESGQPKSLECPSCSSKFASTVALSQHQVRCNVPTVCIICGRTMASFTSLQYHMNKHKGLKPYHCSNCPAKYSNPGARNQHEQRCLRRKNPAGKLKANTLTLCDRCGQDCRTVRQLRKHQNNCNVSKTCGICNRVLHSHNALRAHLNRHNNVKPYQCRESVQCGARFHASGQRNTHERGCPFRAKTSDGSGQITCEGCGKSFTKAVHLQSHETLCVGRQFGADSGEDLEELPEDTNLPVGEQECESKPIENHEDPAPATWSTTSCVGCGEDFASTELMQSHKQSCGTKKTCTVCRKSVVIDHFEFHMNRHSGVNPYSCRVRDDCPAAFHNPWLRNKHERICRGGPEKKTDPEDGKCRRCGKELDRQTMLHVCEGFQMEQEEKVIKWSYMKEVEPSSVKVESVDVKVEEKKPVDEEDLLEVTFEQPVDLRFFCEACGKEFNSSELRNKHTSSCDKALPYQCRLSAECPERFANAQYRRNHEVICGKSRRLGGKSVKVELVACRNCGKVCNGKQLLRVHRELCGPEVELPAELRCTVCSEVSDSVEKLQKHLDEHNREKLLKCRASANCLESFKQQRTRIDHELECTAAGQTICSKCFKLLPNPDSLEDHEDSCQGDEFMCRLCDATYSDVLGLRKHLLNHENPGQHARWWEKPTRNPVTPNRQRYSCENCGQEFVTQEELQKHPALCKFIYRCAECPAAFAKALSLKFHENMHSGAKPFECRKEGCTKGFGNPYHRRAHEELCGTSKAEEHLKKVEQGGTSTAAKMFPCPHCTATFKAVNELKYHVNEHKANEMFPCRQSDDCQETFTTRGFRLKHEAICGKLAAPKQPRKVELIACKDCGKVFSNLQYLRIHKQKCAGSEEGPPSNLKCTLCTVISPDVEALQEHLDGHNREKPFQCRISKACSESYINERQRGNHELVCNADGQVICQRCFKLCPCLETLKSHEKICRGTEFPCRLCEVVLRTRNSQLVHYLRHDNEKKQSNRMHVCPSCDKQFHKRTNFLLHLKEHNIDPSDLKLKCEICAATFKAMKTMEIHMNCHKGIKSYKCRYQGCEEAFFQSAAREVHEQNCTKVSLTCDICELKLVCMRDYQLHIRSHDAANSLEGM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401967;
90% Identity: iTF_00401967;
80% Identity: -