Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: -
Assembly: GCA_015732765.1
Location: NC:13324149-13330253[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0005 0.014 15.5 0.5 2 23 405 426 404 426 0.96

2 12 8.5e-05 0.0024 18.0 0.8 1 23 435 457 435 457 0.99

3 12 0.0063 0.18 12.1 2.1 2 23 465 486 464 486 0.96

4 12 6.1e-07 1.7e-05 24.7 0.3 1 23 492 514 492 514 0.99

5 12 1.8e-05 0.0005 20.1 1.9 1 23 521 543 521 543 0.97

6 12 9.1e-05 0.0026 17.9 1.4 1 23 549 571 549 571 0.96

7 12 0.0001 0.003 17.7 0.3 1 23 577 599 577 599 0.98

8 12 1.6e-06 4.5e-05 23.4 0.5 1 23 605 628 605 628 0.96

9 12 0.0035 0.1 12.9 6.7 1 23 634 657 634 657 0.96

10 12 0.00011 0.0032 17.6 1.5 1 23 663 685 663 685 0.99

11 12 0.00054 0.015 15.4 0.9 1 23 691 713 691 713 0.96

12 12 0.0043 0.12 12.6 0.2 1 22 719 740 719 743 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0005	0.014	15.5	0.5	2	23	405	426	404	426	0.96
2	12	8.5e-05	0.0024	18.0	0.8	1	23	435	457	435	457	0.99
3	12	0.0063	0.18	12.1	2.1	2	23	465	486	464	486	0.96
4	12	6.1e-07	1.7e-05	24.7	0.3	1	23	492	514	492	514	0.99
5	12	1.8e-05	0.0005	20.1	1.9	1	23	521	543	521	543	0.97
6	12	9.1e-05	0.0026	17.9	1.4	1	23	549	571	549	571	0.96
7	12	0.0001	0.003	17.7	0.3	1	23	577	599	577	599	0.98
8	12	1.6e-06	4.5e-05	23.4	0.5	1	23	605	628	605	628	0.96
9	12	0.0035	0.1	12.9	6.7	1	23	634	657	634	657	0.96
10	12	0.00011	0.0032	17.6	1.5	1	23	663	685	663	685	0.99
11	12	0.00054	0.015	15.4	0.9	1	23	691	713	691	713	0.96
12	12	0.0043	0.12	12.6	0.2	1	22	719	740	719	743	0.92

Sequence Information

Coding Sequence: ATGAACATGATGCTCGGCGAGGCTGCGGCCGTGGTCCTGGGAGACCTCCACGACCAGCATCACCAGTTTGAGGAAACAGACCCGCTGTACTGCTACGTTTGCAACGTGGCCATCTCGAGCGCTGCCGACGAATCGATTGGCCAACTCTGCCAACTGTTCCCGATCATAACGGACGAGGAAGATGAAGCGCTCAGTCCTGCGCACATCCTCTCGAATCTGCTGCAGATCGACATCACGCCGGAGCTGTCCCACTCGCAGGCCATCTGTCTGCAGTGCAATCTGCTGTGCAACGAGTACCAACACCTGCTGGACCGTCTCGACTCGATCAAGTTGCAGTTGACCGTTAGCTACAACAGTACTGTGGCGAAACTGACCGCCAGTTTGACGGCCAAAGATCTGGTCGACGCGGAGGCGGAAGCGCTGGACGACGACGTTTCGCAGGGCTTGGAGCTTGCGGACCCAAATGCGGACATTATCACCCTCGGAGATTTGACCGCTGTCGTTCCGGCCTCATCGGAGGTGACGGACATGGATTCCGAACCAACCATCATCCGCCAAATGCCCAAGTTACACTTCATACCACGGCCAACGGAGTGCAGCTCGCCAACCAGAAACAGCAACTCCAGGTCCATCATCAAGATGGTCCCAAAGGACGTCGAAACCGCCACCACGGACGTCTTCATCAAGTCCGAGATCTGCGAAATCCCGTCAACCATTACGATGGAGCAGTTCTTCGAGGGTAGCGACGGCAACATGGTGGAGATCATCGCCGACGAGGGCGATCCGGATTACATCTACGACAACGTGATCGAAACCATCGGCGGAGGATCCGGCGGCGGGGAGGCCGACGAAGACCCGGGTGGAAGTGACGGGGCGGAAGAAATCGGGACCACTACCATTTTGACGCAGGACGCCGATGGAAACGCGCTCGAGCTGACGAGTTGTTTGGCCAAGGACACCCAGCTACTGGCGGCAGGCGGGAGCACGCATCGAAGGCTGGAGGAGGACGACGGGGATGTTGCGGACGTGTTGATTGCGGCTGCGAACGAGAGTTtggatcggatggtgaagtCGAAGCTGGAGTCGctctttttcaaaaccaaCGACAACTACTACTGCACGCTCTGTCCCGCCAGCGACGGTCCGCCGGCGGCCCACAATGTCAAAACCATCGGAATCCACCTGAAAACGGATCACGACGAAAAGATCCTGATCTGCGAGCGCTGCGATGCGGTCTTCCGGCGACGCACCCAGTACAACGAGCACATGGACAAGCACGTGGCATCGGAGCTCGGGTCGGACTTTCGATGCGACGTCTGTGGGACGGAGTTTGCAAACATCCGGACGCTGCGGATGCACCGTAAGACGCACGTGGCCACGCCCAAGGTTTGGTCATGCCACGTGTGCCAGAAGAAGTACAGCAGTAAAAATCTGCTAGACGAGCACAGCAACATGCACTCTGGGAAGCGTCCGTTCAAGTGTCCTGTTTGTCCGAAGGACTTCGCCTCCAAGTACACGCTGTCCGCTCACATGAAGATCCACCAGGACCGGGAGCGGGTGTTCAACTGCAAAGAGTGCGGCCGTGGCTTCTACAGCCAACATAATCTAATTCAGCACGAAAAGATCCACCTCGGAGTGAGGGATTATGCGTGCACAGATTGCAACAAAACGTTCATGTCGCAGCACAACCTGGACATTCACAAGATCGTTCACCTCAACTACAAACCGTTCATCTGCCGTACGTGTGGGAAGGGTTTTGCGCGGAAGGCGGAAATTAAGGACCACGAACGGACGCACACCGGCGAGCGTCCGTTTGTCTGTGATATCTGCGACGCGAGTTTCTCGCAGCGGTCCAACCTGCAGTCGCACAAGCGAGCAACGCACTTCAACGATAAGCGGTACAAGTGTGACCTCTGCAACCGGTGCTTCAAGCGGCGCCGTCTGCTCGATTACCACATCAAGGCGTGTCACACCGGCGAACGGCCGTACAAGTGCGAAGTTTGCGCGGCGACCTTCGTCTACCCGGAACACTTTAAAAAGCACCAGAAGATCCACACCGGCTCGAAACCGTTCGCCTGCGAAGTGTGCAGCAAGACGTTCAACAGCCGGGACAACCGGAACGCGCACCGTTTTGTCCACAGCGACAAGAAACCGTACGAGTGCGTGACCTGCGGGGCCGGATTCATGCGCAAACCGCAACTGTACTCGCACATGCAGCAGCGGGGCCACCTGAACGATACGATCGTCGTGAACCAGCCGCGCATTACGAACGACGACTTGCTCGAGTTTGACACGACGACCGATTCCATCGGCGATCCGCTCGAGCTGGACAAGCAGGGAATCGTCTACGAGGAAGATCCGGACGAGCTGGAGGGCGCGCGGGATGAGTACTACATCGAGGAGGAGGAAATGGAAGAGGACGAtggcgaggaggaggaggacgacgaAGGAGGAGCGATTCCCGGAACGAGCCAGCTGGTGCTGCCCGGTACGGTGGAGCTGTCCGAGTCGACGGCACTGTTGGCCGCCAGTGAGGGCTTTATCGACGAAACGGACATCATCAGTCAGGATTTggacgacgatgatgacgagGAAGGTGGTGCTGGGTCTGGAGGTGGGATGCAGTTGGTGAAGCTGAAGATTGCCAACCCCAACGGAAAGGATGGCATCGCGTGGGTGAATTTGGTTTCTCAGTGA
Protein Sequence: MNMMLGEAAAVVLGDLHDQHHQFEETDPLYCYVCNVAISSAADESIGQLCQLFPIITDEEDEALSPAHILSNLLQIDITPELSHSQAICLQCNLLCNEYQHLLDRLDSIKLQLTVSYNSTVAKLTASLTAKDLVDAEAEALDDDVSQGLELADPNADIITLGDLTAVVPASSEVTDMDSEPTIIRQMPKLHFIPRPTECSSPTRNSNSRSIIKMVPKDVETATTDVFIKSEICEIPSTITMEQFFEGSDGNMVEIIADEGDPDYIYDNVIETIGGGSGGGEADEDPGGSDGAEEIGTTTILTQDADGNALELTSCLAKDTQLLAAGGSTHRRLEEDDGDVADVLIAAANESLDRMVKSKLESLFFKTNDNYYCTLCPASDGPPAAHNVKTIGIHLKTDHDEKILICERCDAVFRRRTQYNEHMDKHVASELGSDFRCDVCGTEFANIRTLRMHRKTHVATPKVWSCHVCQKKYSSKNLLDEHSNMHSGKRPFKCPVCPKDFASKYTLSAHMKIHQDRERVFNCKECGRGFYSQHNLIQHEKIHLGVRDYACTDCNKTFMSQHNLDIHKIVHLNYKPFICRTCGKGFARKAEIKDHERTHTGERPFVCDICDASFSQRSNLQSHKRATHFNDKRYKCDLCNRCFKRRRLLDYHIKACHTGERPYKCEVCAATFVYPEHFKKHQKIHTGSKPFACEVCSKTFNSRDNRNAHRFVHSDKKPYECVTCGAGFMRKPQLYSHMQQRGHLNDTIVVNQPRITNDDLLEFDTTTDSIGDPLELDKQGIVYEEDPDELEGARDEYYIEEEEMEEDDGEEEEDDEGGAIPGTSQLVLPGTVELSESTALLAASEGFIDETDIISQDLDDDDDEEGGAGSGGGMQLVKLKIANPNGKDGIAWVNLVSQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400834;
90% Identity: iTF_00400834;
80% Identity: -