Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:210455909-210467763[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00081 0.025 15.5 0.5 2 23 407 428 406 428 0.96

2 12 0.00014 0.0043 18.0 0.8 1 23 437 459 437 459 0.99

3 12 0.01 0.31 12.1 2.1 2 23 467 488 466 488 0.96

4 12 9.9e-07 3e-05 24.7 0.3 1 23 494 516 494 516 0.99

5 12 2.4e-05 0.00072 20.4 0.6 1 23 523 545 523 545 0.97

6 12 0.00015 0.0046 17.9 1.4 1 23 551 573 551 573 0.96

7 12 0.00017 0.0052 17.7 0.3 1 23 579 601 579 601 0.98

8 12 2.6e-06 7.8e-05 23.4 0.5 1 23 607 630 607 630 0.96

9 12 0.0057 0.18 12.9 6.7 1 23 636 659 636 659 0.96

10 12 0.00018 0.0056 17.6 1.5 1 23 665 687 665 687 0.99

11 12 0.00088 0.027 15.4 0.9 1 23 693 715 693 715 0.96

12 12 0.007 0.22 12.6 0.2 1 22 721 742 721 745 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00081	0.025	15.5	0.5	2	23	407	428	406	428	0.96
2	12	0.00014	0.0043	18.0	0.8	1	23	437	459	437	459	0.99
3	12	0.01	0.31	12.1	2.1	2	23	467	488	466	488	0.96
4	12	9.9e-07	3e-05	24.7	0.3	1	23	494	516	494	516	0.99
5	12	2.4e-05	0.00072	20.4	0.6	1	23	523	545	523	545	0.97
6	12	0.00015	0.0046	17.9	1.4	1	23	551	573	551	573	0.96
7	12	0.00017	0.0052	17.7	0.3	1	23	579	601	579	601	0.98
8	12	2.6e-06	7.8e-05	23.4	0.5	1	23	607	630	607	630	0.96
9	12	0.0057	0.18	12.9	6.7	1	23	636	659	636	659	0.96
10	12	0.00018	0.0056	17.6	1.5	1	23	665	687	665	687	0.99
11	12	0.00088	0.027	15.4	0.9	1	23	693	715	693	715	0.96
12	12	0.007	0.22	12.6	0.2	1	22	721	742	721	745	0.92

Sequence Information

Coding Sequence: ATGAACATGATGCTCGGCGAGGCTGCGGCCGTGGTCCTGGGAGACCTCCACGACCAGCATCACCAGTTTGAGGAAACAGACCCGCTGTACTGCTACGTTTGCAACGTGGCCATCTCGAGCGCTGCCGACGAATCGATTGGCCAACTCTGCCAACTGTTCCCGATCATAACGGACGAGGAAGATGAAGCGCTCAGTCCTGCGCACATTCTCTCGAATCTGCTGCAGATCGACATCACGCCGGAGCTGTCCCACTCGCAGGCCATCTGTCTGCAGTGCAATCTGCTGTGCAACGAGTACCAACACCTGCTGGACCGTCTCGACTCGATCAAGTTGCAGTTGACCGTTAGCTACAACAGTACTGTGGCGAAGCTGACCGCCAGTTTGACGGCCAAGGATCTAGCCGATGCGGAGGCGGAAGCGCTGGACGACGACGTTTCGCAGGGCTTGGAGCTTGCGGACCCAAATGCGGACATTATCACCATCCCCCTCGGAGATTTGACCGCGGTAGTTCCAGCCTCATCGGAGGTGACGGACATGGATTCCGAGCCAACCATCATCCGTCAAATGCCCAAGTTACACTTCATACCACGGGCAACGGAGCCCAGCTCGCCAACCAGAAACAGCAACTCCAGGTCCATCATCAAGATGGTCCCAAAAGACGCCGAAACCGCCCCCACGGACGTCTTCATCAAGTCCGAGATCTGCGAGATCCCGTCAACCATTACGATGGAGCAGTTCTTCGAGGGAAGCGACGGCAACATGGTGGAGATCATCGCCGACGAGGGCGATCCGGATTACATCTACGACAACGTGATCGAAACCATCGACGGAGGACCCGGTGGCGGGGATGACGACGAAGACCCCGGTGGAAGTGACGGGGCGGAAGAAATCGGAACCACCACCATTTTGACGCTGGACGCCGATGGAAACGCGCTCGAGCTGACGAGTTGTTTGGACCGGGACACGCAGCTACTGGCGGCAGGCGGGAGCACGCACCGAAGGCTGGAGGAGGACGACGGGGATGTGGCGGACGTGTTGATTGCGGCCGCGAACGAGAGTTtggatcggatggtgaagtCGAAGCTGGAGTCgCTCTTTTTCAAAACCAACGACAACTACTACTGCACGCTCTGTCCCGCCAGCGACGGTCCGCCGGCGGCCCACAATGTCAAAACCATCGGAATCCACCTGAAAACGGATCACGACGAAAAGATCCTGATCTGCGAGCGCTGCGATGCGGTCTTCCGGCGACGCACCCAGTACAACGAGCACATGGACAAGCACGTGGCATCGGAGCTCGGGTCGGACTTTCGATGCGACGTCTGTGGGACGGAGTTTGCAAACATCCGGACGCTGCGGATGCACCGGAAGACGCACGTGGCCACGCCCAAGGTTTGGTCCTGCCACGTGTGTCAGAAAAAGTACAGCAGTAAAAATCTGCTTGACGAGCACAGCAACATGCACTCTGGGAAGCGTCCGTTCAAGTGTCCGGTCTGTCCGAAGGACTTCGCCTCCAAGTACACGCTGTCCGCTCACATGAAGATCCACCAGGACCGGGAGCGCGTGTTCAACTGTAAAGAGTGCGGCCGTGGCTTCTATAGCCAGAACAATCTGATTCAGCACGAAAAGATCCACCTCGGAGTGAGGGATTATGCGTGCACAGATTGCAACAAAACGTTCATGTCGCAGCACAACCTGGATATTCACAAGATCGTACACCTCAACTACAAACCGTTCATCTGCCGTACCTGTGGGAAGGGCTTTGCGCGGAAGGCGGAAATTAAGGACCACGAACGGACGCACACCGGCGAGCGTCCGTTTGTCTGTGATATCTGCGACGCGAGCTTCTCGCAGCGGTCCAACCTGCAGTCGCACAAGCGAGCAACGCACTTCAACGATAAGCGGTACAAGTGTGACCTCTGCAACCGGTGCTTCAAGCGGCGCCGTCTGCTCGATTACCACATCAAGGCGTGTCACACCGGCGAACGGCCGTACAAGTGCGAAGTTTGCGCGGCGACCTTCGTCTACCCGGAACACTTTAAAAAGCACCAGAAGATCCACACCGGCTCGAAACCGTTCGCCTGCGAAGTGTGCAGCAAGACGTTCAACAGCCGGGACAACCGGAACGCGCACCGTTTTGTCCACAGCGACAAGAAACCGTACGAGTGCGTGACCTGCGGGGCCGGATTCATGCGCAAACCGCAACTGTACTCGCACATGCAGCAGCGGGGCCACCTGAACGATACGATCGTCGTGAACCAGCCGCGCATTACGAACGACGACTTGCTCGAGTTTGACACGACGACCGATTCCATCGGCGATCCGCTCGAGCTGGACAAGCAGGGAATCGTCTACGAGGAAGATCCGGACGAGCTGGAGGGCGCGCGGGATGAGTACTACATCGAGGAGGAGGAAATGGAAGAGGACGAtggcgaggaggaggacgacgacgaaGGAGGAGCGATTCCCGGAACGAGCCAGCTGGTGCTGCCCGGTACGGTGGAGCTGTCCGAGTCGACGGCACTGTTGGCCGCCAGTGAGGGCTTTATCGACGAAACGGACATCATCAGTCAGGATTtggacgacgatgatgacgagGAAGGTGGTGCTGGGCCTGGAGGTGGGATACAGTTGGTGAAGCTGAAAATTGCCAACCCCAATGGAAAGGATGGCATCGCGTGGGTGAATTTGGTTTCTCAGTGA
Protein Sequence: MNMMLGEAAAVVLGDLHDQHHQFEETDPLYCYVCNVAISSAADESIGQLCQLFPIITDEEDEALSPAHILSNLLQIDITPELSHSQAICLQCNLLCNEYQHLLDRLDSIKLQLTVSYNSTVAKLTASLTAKDLADAEAEALDDDVSQGLELADPNADIITIPLGDLTAVVPASSEVTDMDSEPTIIRQMPKLHFIPRATEPSSPTRNSNSRSIIKMVPKDAETAPTDVFIKSEICEIPSTITMEQFFEGSDGNMVEIIADEGDPDYIYDNVIETIDGGPGGGDDDEDPGGSDGAEEIGTTTILTLDADGNALELTSCLDRDTQLLAAGGSTHRRLEEDDGDVADVLIAAANESLDRMVKSKLESLFFKTNDNYYCTLCPASDGPPAAHNVKTIGIHLKTDHDEKILICERCDAVFRRRTQYNEHMDKHVASELGSDFRCDVCGTEFANIRTLRMHRKTHVATPKVWSCHVCQKKYSSKNLLDEHSNMHSGKRPFKCPVCPKDFASKYTLSAHMKIHQDRERVFNCKECGRGFYSQNNLIQHEKIHLGVRDYACTDCNKTFMSQHNLDIHKIVHLNYKPFICRTCGKGFARKAEIKDHERTHTGERPFVCDICDASFSQRSNLQSHKRATHFNDKRYKCDLCNRCFKRRRLLDYHIKACHTGERPYKCEVCAATFVYPEHFKKHQKIHTGSKPFACEVCSKTFNSRDNRNAHRFVHSDKKPYECVTCGAGFMRKPQLYSHMQQRGHLNDTIVVNQPRITNDDLLEFDTTTDSIGDPLELDKQGIVYEEDPDELEGARDEYYIEEEEMEEDDGEEEDDDEGGAIPGTSQLVLPGTVELSESTALLAASEGFIDETDIISQDLDDDDDEEGGAGPGGGIQLVKLKIANPNGKDGIAWVNLVSQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401938;
90% Identity: iTF_00401938;
80% Identity: -