Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: -
Assembly: GCA_015732765.1
Location: NC:76685961-76691958[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.004 0.11 12.7 0.5 2 23 183 205 183 205 0.97

2 18 0.72 21 5.6 0.1 3 23 212 232 210 232 0.96

3 18 0.0024 0.068 13.4 4.2 1 23 238 260 238 260 0.97

4 18 8e-06 0.00023 21.2 1.9 1 23 266 288 266 288 0.98

5 18 0.00038 0.011 15.9 0.7 1 23 294 316 294 316 0.98

6 18 9.2e-05 0.0026 17.9 1.7 1 23 322 345 322 345 0.97

7 18 2.5e-05 0.00071 19.6 5.0 1 23 351 373 351 373 0.98

8 18 9.6e-05 0.0027 17.8 0.3 1 23 379 401 379 401 0.98

9 18 0.0058 0.16 12.2 0.3 1 23 407 429 407 429 0.97

10 18 1.5 43 4.6 0.8 1 23 721 744 721 744 0.93

11 18 0.00027 0.0076 16.4 1.3 1 23 749 771 749 771 0.98

12 18 0.00011 0.0031 17.6 1.4 2 23 778 799 778 799 0.98

13 18 5e-06 0.00014 21.8 2.9 1 23 804 826 804 826 0.98

14 18 0.0048 0.14 12.5 0.1 1 23 832 854 832 854 0.97

15 18 0.00016 0.0047 17.1 0.4 1 23 860 883 860 883 0.96

16 18 5.5e-06 0.00016 21.7 4.1 1 23 889 911 889 911 0.97

17 18 9e-05 0.0026 17.9 0.2 1 23 917 939 917 939 0.98

18 18 0.028 0.79 10.0 0.1 1 23 945 967 945 967 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.004	0.11	12.7	0.5	2	23	183	205	183	205	0.97
2	18	0.72	21	5.6	0.1	3	23	212	232	210	232	0.96
3	18	0.0024	0.068	13.4	4.2	1	23	238	260	238	260	0.97
4	18	8e-06	0.00023	21.2	1.9	1	23	266	288	266	288	0.98
5	18	0.00038	0.011	15.9	0.7	1	23	294	316	294	316	0.98
6	18	9.2e-05	0.0026	17.9	1.7	1	23	322	345	322	345	0.97
7	18	2.5e-05	0.00071	19.6	5.0	1	23	351	373	351	373	0.98
8	18	9.6e-05	0.0027	17.8	0.3	1	23	379	401	379	401	0.98
9	18	0.0058	0.16	12.2	0.3	1	23	407	429	407	429	0.97
10	18	1.5	43	4.6	0.8	1	23	721	744	721	744	0.93
11	18	0.00027	0.0076	16.4	1.3	1	23	749	771	749	771	0.98
12	18	0.00011	0.0031	17.6	1.4	2	23	778	799	778	799	0.98
13	18	5e-06	0.00014	21.8	2.9	1	23	804	826	804	826	0.98
14	18	0.0048	0.14	12.5	0.1	1	23	832	854	832	854	0.97
15	18	0.00016	0.0047	17.1	0.4	1	23	860	883	860	883	0.96
16	18	5.5e-06	0.00016	21.7	4.1	1	23	889	911	889	911	0.97
17	18	9e-05	0.0026	17.9	0.2	1	23	917	939	917	939	0.98
18	18	0.028	0.79	10.0	0.1	1	23	945	967	945	967	0.97

Sequence Information

Coding Sequence: ATGGACCCAAAATCGAGTGTTTCCGCGCTGTGTCGTGTCTGTATGAAGACCACCAAGGAGAGCAAATCGGACAACATCTACCGGTCGTCGTCCGATCCGGACCAGCCGAATCTATACGAGATGCTTGGTGCGATCTGCCCTCCGGCATTCCCCGGAGCAAACGAGAGGCACGAAACGAAGGTTTCCTCCGGATTGCCCAGCGTCGTCTGTTTGATCTGCAAGTCGGGCGTCGTGGCCGCCTACGAGATTCACCGGAAGTGTATCGAAACCGATCGGAAGCTACGGGAGATGGTAGTGGTTAAGCAGGAAGTGCTGGACGAGGATGAGGAGGGCGATGAAGTGGAACAGGAGACGGTGGTGGTTCACGCGGACCCGCTGGTTCATATGGAGGAGGACCATGACGACAAGGACGGGATACTGTCCGACGTGGATTTTCAAGGGGCAGATTCGGACGAAAGTTATCACGAGAAACCACGAAGAGGGCGGAGGAAAAAGACGGTGACGGTGCCGGCAAAGCCTTCCTCGGGTAAGATCAAGAACAAGCGAACTTGCGAGCTGTGCTCGGTCGTGTTCAAGACGATCAAAGAAATGAAGGGCCACATGAGAACGGATCATCCTGGCGATGTTTTTGGCTGCGAGGTTTGTGACGACGTTTTTGTGGACGAAACTAAGTTCGAGGAGCACAAAATCAGTCACACGTCGGAGCGACCACATGAGTGTAGCTATTGCAAGGAAAAGTTCCGGTCTCTTACGGATCTCAAGTACCATACGATGAATCACACCAATGATCATCCGTTCCGATGCTCTGTGTGCGGAAAAGGGTTCCCTAAGAAACACGCACTGCAGTATCACATGCTTCGGCATACCGGAGAGAAGCCCTTCGTCTGTCAGCAGTGTCCTTCGAAGTTCTACTCCAAAGGAGAGCTCAAAATGCACATGGTCACTCACACGCTGGAAAAGAATCACGTTTGCGACGTCTGCGGAAACCGATTTACCAAGAATACCTCACTGATGAAGCATGTCAGACGAGTTCACGCTGGATTACGGCCGTTCCCCTGCAGTCTGTGTACCTTGAAATTCGACAACGCTCACCACCTGAAGCGGCACATGAGAACCCACACCGGAGAAAAGCCGTACAAATGTGCATACTGTGACCGGGCGTACGCCCAGAGTAACGATCTGGTCAAGCACAGCAAGATCCACGTCGGACAGAATCCGTACGCGTGCGATCGGTGCGACGCGGCCTTCCGGCTGATGACCGAGCTGCGCAACCACTATAAGGTTCACTTCCAGCCGGGCGATCAGAGCGAAGCCAACGCAACCAGCGCGCTGGTCAAGAAGCACGAAAGCAAAGCCGGCAAGGAGCAGGTCGAGTTCACCAGTATGGCCACGCTGAATCGGCGGTTTGAGCAGGAAATGCAACGGAAGGAGAGTGAACAACAGCAACAGCTACAGCaacttcagcagcagcagcagctacaACCTGCGGATGCTCCGGTGAACTTTGGACTGAACTTCTCGTCGCGGTTTTACGTATGCGTCACCATGTGCTTCTTCAGTTCGCCCTTGGTGTGGAATCTGGACGGACACAGGCCGCAAACGAACGCCTTGTCCGAAGTGTGCCGAAGATTCTCGACAACAATGCAGAACAATATGGGACAACTTTGTCGCGTGTGCATGAAGTCCGCACCACCGGACACCTCCCAAAACATCTACGCACCGCTGGCCGATCCGAGCCAGCCGAACCTTCATCGAATGCTTGCCAGTGTTTGCGCTCCAGTTTTCTCGTGTTCCGAGGATTCGAACAATCAGGACAGCAAGGAATCGCTCGGATTACCGAAGATCGTGTGTGCCCCTTGCAAGCAAAGCGTTCTGGACGCTTACAAACTGCACATGAAATGTATTGAAACCGATCGACGCCTGTGGGAAATGATTCGGGTTAAGCAGGAGCTACACATCGATGATGATGAAGATCGAGTGCTACCGGAAAGCTCGGATGATCCGCTGTTGGAGGAGCAGGAGGAATGCTCTCTGAAAGAGGAAGTTGAGGATGACGACAGCGATGAGGTTTGGATGGAACCAGCTGAGGATTCCAACGACGATGAAGGAAATAGCCGGAAGAAAGCTGGGAAGAAGCCAAGACCGTACTGCCCTAGGAAGCACAGATGCGAGAGTTGCACGGATGTCTTTACCTCGATTCGGGTACTCAAGCAGCACATCATAGAGCAACATCCAGAAAAGGCATACAAATGTTGTATGTGCGATAAGGCCTTCTTCAACGAGGCGCTGCTCAGCAGTCACATGCTTGGGCACACAACCGGAAAGGGTCGGGAGTGCCACGTTTGCCAAGCCCGATTCAAGTCGTATTCCGGACTGAAGGCCCACCTCAACACACACTCCGGATCGCTGTTTATGTGTTCGGTTTGCGACAAAAAATTTACCAGCAAACACACCTTGGAAGTGCACATTCAGCGACATGCCGGCAAGAAACCATTCAGCTGCAGTCAATGTCCGATGCGATTCGTGACCAGAGCGGAAGTTAGGGTCCACGGCGCTACGCACAACAAGGTGCAGAATCACGTTTGCGACGTCTGCGGTTCAAGATTCACGCGGAAGGTGTCACTCGTCAACCACGTCAAGGTTGTCCACGCTGGTGTACGACCCCATCCTTGTATGTTATGCCCTCTGAAATTTTCCACCTCAGATCACCTGAAACGGCACATGCGAACCCACACCGGGGAAAAACCGTTCAAATGTGCCTACTGCGACCGGGCGTACGCCCAAAGCGGCGATCTGGTCAAGCACAGCAAGATCCACGTCGGGGAAAATCCGTACGCGTGCGATCGGTGCGACGCGGCCTTCCGGCTGATAACCGAGCTGAGGAACCACTACACCGTGCACTACCAGTCGGATGAGCGCCAGAGTGACAAGGACAAACCTTTGGTGTTTACCAGCCAGGCGACGCTGGAAAGACGCTTCGAGCAGGAAAAGTTACTCGGTGGACAGTCCGGAAAGGGGGAGAGTAACCGTTGTGATTAG
Protein Sequence: MDPKSSVSALCRVCMKTTKESKSDNIYRSSSDPDQPNLYEMLGAICPPAFPGANERHETKVSSGLPSVVCLICKSGVVAAYEIHRKCIETDRKLREMVVVKQEVLDEDEEGDEVEQETVVVHADPLVHMEEDHDDKDGILSDVDFQGADSDESYHEKPRRGRRKKTVTVPAKPSSGKIKNKRTCELCSVVFKTIKEMKGHMRTDHPGDVFGCEVCDDVFVDETKFEEHKISHTSERPHECSYCKEKFRSLTDLKYHTMNHTNDHPFRCSVCGKGFPKKHALQYHMLRHTGEKPFVCQQCPSKFYSKGELKMHMVTHTLEKNHVCDVCGNRFTKNTSLMKHVRRVHAGLRPFPCSLCTLKFDNAHHLKRHMRTHTGEKPYKCAYCDRAYAQSNDLVKHSKIHVGQNPYACDRCDAAFRLMTELRNHYKVHFQPGDQSEANATSALVKKHESKAGKEQVEFTSMATLNRRFEQEMQRKESEQQQQLQQLQQQQQLQPADAPVNFGLNFSSRFYVCVTMCFFSSPLVWNLDGHRPQTNALSEVCRRFSTTMQNNMGQLCRVCMKSAPPDTSQNIYAPLADPSQPNLHRMLASVCAPVFSCSEDSNNQDSKESLGLPKIVCAPCKQSVLDAYKLHMKCIETDRRLWEMIRVKQELHIDDDEDRVLPESSDDPLLEEQEECSLKEEVEDDDSDEVWMEPAEDSNDDEGNSRKKAGKKPRPYCPRKHRCESCTDVFTSIRVLKQHIIEQHPEKAYKCCMCDKAFFNEALLSSHMLGHTTGKGRECHVCQARFKSYSGLKAHLNTHSGSLFMCSVCDKKFTSKHTLEVHIQRHAGKKPFSCSQCPMRFVTRAEVRVHGATHNKVQNHVCDVCGSRFTRKVSLVNHVKVVHAGVRPHPCMLCPLKFSTSDHLKRHMRTHTGEKPFKCAYCDRAYAQSGDLVKHSKIHVGENPYACDRCDAAFRLITELRNHYTVHYQSDERQSDKDKPLVFTSQATLERRFEQEKLLGGQSGKGESNRCD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400807;
90% Identity: iTF_00400807;
80% Identity: -