Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:143170452-143176418[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0064 0.2 12.7 0.5 2 23 183 205 183 205 0.97

2 18 1.2 36 5.6 0.1 3 23 212 232 210 232 0.96

3 18 0.0038 0.12 13.4 4.2 1 23 238 260 238 260 0.97

4 18 1.3e-05 0.0004 21.2 1.9 1 23 266 288 266 288 0.98

5 18 0.0006 0.018 15.9 0.7 1 23 294 316 294 316 0.98

6 18 0.00015 0.0045 17.9 1.7 1 23 322 345 322 345 0.97

7 18 4e-05 0.0012 19.7 5.0 1 23 351 373 351 373 0.98

8 18 0.00015 0.0047 17.8 0.3 1 23 379 401 379 401 0.98

9 18 0.0093 0.29 12.2 0.3 1 23 407 429 407 429 0.97

10 18 2.4 74 4.6 0.8 1 23 714 737 714 737 0.93

11 18 0.00043 0.013 16.4 1.3 1 23 742 764 742 764 0.98

12 18 0.00017 0.0054 17.6 1.4 2 23 771 792 771 792 0.98

13 18 8e-06 0.00024 21.9 2.9 1 23 797 819 797 819 0.98

14 18 0.0049 0.15 13.1 0.1 1 23 825 847 825 847 0.97

15 18 0.00015 0.0045 17.9 0.4 1 23 853 876 853 876 0.96

16 18 8.9e-06 0.00027 21.7 4.1 1 23 882 904 882 904 0.97

17 18 0.00014 0.0044 17.9 0.2 1 23 910 932 910 932 0.98

18 18 0.045 1.4 10.1 0.1 1 23 938 960 938 960 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0064	0.2	12.7	0.5	2	23	183	205	183	205	0.97
2	18	1.2	36	5.6	0.1	3	23	212	232	210	232	0.96
3	18	0.0038	0.12	13.4	4.2	1	23	238	260	238	260	0.97
4	18	1.3e-05	0.0004	21.2	1.9	1	23	266	288	266	288	0.98
5	18	0.0006	0.018	15.9	0.7	1	23	294	316	294	316	0.98
6	18	0.00015	0.0045	17.9	1.7	1	23	322	345	322	345	0.97
7	18	4e-05	0.0012	19.7	5.0	1	23	351	373	351	373	0.98
8	18	0.00015	0.0047	17.8	0.3	1	23	379	401	379	401	0.98
9	18	0.0093	0.29	12.2	0.3	1	23	407	429	407	429	0.97
10	18	2.4	74	4.6	0.8	1	23	714	737	714	737	0.93
11	18	0.00043	0.013	16.4	1.3	1	23	742	764	742	764	0.98
12	18	0.00017	0.0054	17.6	1.4	2	23	771	792	771	792	0.98
13	18	8e-06	0.00024	21.9	2.9	1	23	797	819	797	819	0.98
14	18	0.0049	0.15	13.1	0.1	1	23	825	847	825	847	0.97
15	18	0.00015	0.0045	17.9	0.4	1	23	853	876	853	876	0.96
16	18	8.9e-06	0.00027	21.7	4.1	1	23	882	904	882	904	0.97
17	18	0.00014	0.0044	17.9	0.2	1	23	910	932	910	932	0.98
18	18	0.045	1.4	10.1	0.1	1	23	938	960	938	960	0.97

Sequence Information

Coding Sequence: ATGGACCCAAAATCGAGTGTTTCCGCGCTGTGTCGTGTCTGTATGAAGACCACCAAAGAAAGCAAATCGGACAACATCTATCGGTCGTCGTCCGATCCGGACCAGCCCAATCTGTACGAGATGCTGGGTGCGATCTGCCCTCCGGCATTCCCCGGAGCAAACGAGAGGCACGAAACGAAGGTGTCCTCCGGATTGCCCAGCATCGTCTGTTTGATCTGCAAGTCGGGCGTCGTGGCCGCCTACGAGATTCACCGGAAGTGCATCGAAACGGATCGGAAGCTACGGGAGATGGTAGTGGTGAAGCAGGAAGTGCTGGACGAGGATGAGGAGGGCGATGAGGTGGAACAGGAGACGGTGGTGGTTCACGCGGACCCGCTGGTTCATATGGAGGAGGACCATGACGACAAGGACGGGATACTGTCCGACGTGGATTTTCAAGGGGCAGATTCGGACGAAAGTTACCACGAGAAACCACGAAGAGGGCGGAGGAAAAAGACGGTGACGGTGCCGGCAAAGCCTTCCTCGGGTAAGATCAAGAACAAGCGAACTTGCGAGCTGTGCTCGGTCGTGTTCAAGACGATCAAAGAAATGAAGGGCCACATGAGAACGGATCATGCTGGCGATGTTTTTGGCTGCGAGGTTTGTGACGACGTTTTTGTGGACGAAACTAAGTTCGAGGAGCACAAAATCAGTCACACGTCGGAGCGACCACATGAGTGTAGCTATTGCAAGGAAAAGTTCCGGTCTCTTACGGATCTCAAGTACCATACGATGAATCACACCAATGATCATCCGTTCCGATGCTCTGTGTGCGGAAAAGGGTTCCCTAAGAAACACGCACTGCAGTATCACATGCTTCGGCATACCGGAGAGAAGCCCTTCGTCTGTCAGCAGTGTCCTTCGAAGTTCTACTCCAAAGGAGAGCTCAAAATGCACATGGTCACTCACACGCTGGAAAAGAATCACGTTTGCGACGTCTGCGGAAACCGATTTACCAAGAATACCTCACTGATGAAGCATGTCAGACGAGTTCACGCTGGATTACGGCCGTTCCCCTGCAGTCTGTGTACCTTGAAATTCGACAACGCCCACCACCTGAAGCGGCACATGAGAACCCACACCGGAGAAAAGCCGTACAAATGTGCATACTGTGACCGGGCGTACGCCCAGAGTAACGATCTGGTCAAGCACAGCAAGATCCACGTCGGACAGAATCCGTACGCGTGCGATCGGTGCGACGCGGCCTTCCGGCTGATGACCGAGCTGCGGAACCACTACAAGGTTCACTTCCAGCCGGGCGATCAGAGCGAAGCCAACGCAACCAGCGCGCTGGTCAAGAAGCACGAAAGCAAAGCCGGCAAGGAGCAGGTCGAGTTCACCAGTATGGCCACGCTGAATCGGCGGTTTGAGCAGGAAATGCAACGGAAGGAGAGTGAACAACAGCAACAGCTACAGCaacttcagcagcagcagcagctacaACCTGCGGATGCTCCGGTGAACTTTGGACTGAACTTCTCGTCGCGGTTTACTATGGAATCGGATACGTCTACGACCTGGCTCCAGCTATCCAAAGGAGTGCTCAACCTTCAACCTTCAACCATCGGATTCTCGATAGCAATGCAGAACAACATGGGACAACTTTGTCGGGTGTGCATGAGGTCCGCACCGCCGGACACCTCCCAAAACATCTACGCACCGCTGGCCGATCCGAGCCAGCCAAACCTTCACCGAATGCTTGCCAGTGTGTGCGCTCCAGTTTTCTCGTGTTCCGAGGATTCGAACAATCAGGACAGCAAGGAATCGCTCGGATTACCGAAGATCGTGTGTGCACCGTGCAAGCAAAGCATCCTGGACGCTTACAAGCTGCACATGAAATGTATTGAAACCGATCGACGCCTTTGGGAAATGATTCGGGTTAAGCAGGAGCTACACATCGATGATGATGAAGAACGAGCGCTACCGGAAAGCTCGGATGATCCGCTGTTGGAGGAGCAGGAGGAATGCTCTCTGAAAGAGGAAGTTGAGGATGACGACAGCGATGAGGTTTGGATGGAACCGGCTGAAGATTCGAATGACGATGAAGGAAATAGCCGGAAGAAAGCTGGGAAGAAGCCAAGACCGTACTGCCCTAGGAAGCATAGATGCGAGAGTTGCACGGATGTCTTCACCTCGATTCGGGTACTCAAGCAGCACATCATTGAGCAACATCCGGAAAAGGCCTACAAATGTTGTATGTGCGATAAGGCCTTCTTCAACGAGGCGCTGCTCAGCAGTCACATGCTTGGGCACACAACCGGAAAGGGTCGGGAGTGCCACGTTTGCCAAGCCCGATTCAAGTCGTATTCCGGACTGAAGGCCCACCTCAACACACACTCCGGATCGCTGTTTATGTGTTCGGTTTGCgacaaaaaatttaccagcaaACACACCCTGGAAGTGCACATTCAGCGACATGCCGGCGAGAAACCATTCACCTGCAGTCAATGTCCGATGCGGTTCGTGACCAGAGCGGAAGTTAGGGTCCACGGCGCTACGCACAACAAGGTGCAGAATCACGTTTGCGACATCTGCGGTTCCCGATTCACGCGGAAGGTATCGCTCGTCAACCACGTCAAGGTTGTCCACGCTGGTGTACGACCCCATCCTTGTATGTTATGCCCTCTGAAATTTTCCACCTCAGATCACCTGAAACGGCACATGCGAACCCACACCGGGGAAAAACCGTTCAAATGTGCCTACTGCGACCGGGCGTACGCCCAAAGCGGCGATCTGGTCAAGCACAGCAAGATCCACGTCGGGGAAAATCCGTACGCGTGCGATCGGTGCGACGCGGCCTTCCGGCTGATAACCGAGCTGAGGAACCACTACACCGTGCACTACCAGTCGGATGAGCGCCAGAGTGACAAGGACAAACCGTTGGTGTTTACCAGCCAGGCGACGCTGGAAAGACGCTTCGAGCAGGAAAAGTTACTCGGTGGACAGTCCGGAAAGGGGGGAGAGTAA
Protein Sequence: MDPKSSVSALCRVCMKTTKESKSDNIYRSSSDPDQPNLYEMLGAICPPAFPGANERHETKVSSGLPSIVCLICKSGVVAAYEIHRKCIETDRKLREMVVVKQEVLDEDEEGDEVEQETVVVHADPLVHMEEDHDDKDGILSDVDFQGADSDESYHEKPRRGRRKKTVTVPAKPSSGKIKNKRTCELCSVVFKTIKEMKGHMRTDHAGDVFGCEVCDDVFVDETKFEEHKISHTSERPHECSYCKEKFRSLTDLKYHTMNHTNDHPFRCSVCGKGFPKKHALQYHMLRHTGEKPFVCQQCPSKFYSKGELKMHMVTHTLEKNHVCDVCGNRFTKNTSLMKHVRRVHAGLRPFPCSLCTLKFDNAHHLKRHMRTHTGEKPYKCAYCDRAYAQSNDLVKHSKIHVGQNPYACDRCDAAFRLMTELRNHYKVHFQPGDQSEANATSALVKKHESKAGKEQVEFTSMATLNRRFEQEMQRKESEQQQQLQQLQQQQQLQPADAPVNFGLNFSSRFTMESDTSTTWLQLSKGVLNLQPSTIGFSIAMQNNMGQLCRVCMRSAPPDTSQNIYAPLADPSQPNLHRMLASVCAPVFSCSEDSNNQDSKESLGLPKIVCAPCKQSILDAYKLHMKCIETDRRLWEMIRVKQELHIDDDEERALPESSDDPLLEEQEECSLKEEVEDDDSDEVWMEPAEDSNDDEGNSRKKAGKKPRPYCPRKHRCESCTDVFTSIRVLKQHIIEQHPEKAYKCCMCDKAFFNEALLSSHMLGHTTGKGRECHVCQARFKSYSGLKAHLNTHSGSLFMCSVCDKKFTSKHTLEVHIQRHAGEKPFTCSQCPMRFVTRAEVRVHGATHNKVQNHVCDICGSRFTRKVSLVNHVKVVHAGVRPHPCMLCPLKFSTSDHLKRHMRTHTGEKPFKCAYCDRAYAQSGDLVKHSKIHVGENPYACDRCDAAFRLITELRNHYTVHYQSDERQSDKDKPLVFTSQATLERRFEQEKLLGGQSGKGGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401914;
90% Identity: iTF_00401914;
80% Identity: -