Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: Prdm14
Assembly: GCA_015732765.1
Location: NC:7734522-7738521[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.52 15 6.1 0.3 8 23 61 76 50 76 0.87

2 23 0.009 0.26 11.6 0.8 2 20 89 107 88 109 0.94

3 23 7.4e-05 0.0021 18.1 2.7 1 23 185 207 185 207 0.98

4 23 0.0099 0.28 11.5 0.1 3 23 332 353 330 353 0.96

5 23 1e-05 0.00028 20.9 0.4 1 23 360 383 360 383 0.98

6 23 0.00094 0.027 14.7 0.6 1 23 388 410 388 410 0.98

7 23 0.27 7.8 6.9 9.7 1 23 415 438 415 438 0.96

8 23 0.0021 0.061 13.6 0.1 1 23 445 467 445 467 0.97

9 23 4e-06 0.00011 22.1 2.2 2 23 474 495 473 495 0.97

10 23 2.8e-05 0.00079 19.5 0.2 1 23 504 526 504 526 0.98

11 23 0.00021 0.0059 16.7 0.4 2 23 530 552 529 552 0.95

12 23 0.066 1.9 8.9 0.4 2 23 562 584 561 584 0.91

13 23 0.00026 0.0074 16.4 0.0 2 23 591 612 590 612 0.97

14 23 0.13 3.8 7.9 1.4 1 23 619 642 619 642 0.93

15 23 0.00015 0.0042 17.2 0.3 1 23 648 670 648 670 0.96

16 23 0.00042 0.012 15.8 2.5 1 23 685 708 685 708 0.92

17 23 0.0011 0.032 14.5 0.1 1 23 714 736 714 736 0.98

18 23 4.4e-06 0.00012 22.0 0.4 1 23 741 763 741 763 0.97

19 23 4.3e-05 0.0012 18.9 0.9 2 23 771 792 771 792 0.98

20 23 0.016 0.46 10.8 1.2 1 23 798 821 798 821 0.96

21 23 0.0031 0.089 13.0 0.1 2 23 826 847 825 847 0.96

22 23 0.031 0.88 9.9 4.2 1 23 853 875 853 875 0.98

23 23 2.9 84 3.7 4.6 1 23 882 905 882 905 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.52	15	6.1	0.3	8	23	61	76	50	76	0.87
2	23	0.009	0.26	11.6	0.8	2	20	89	107	88	109	0.94
3	23	7.4e-05	0.0021	18.1	2.7	1	23	185	207	185	207	0.98
4	23	0.0099	0.28	11.5	0.1	3	23	332	353	330	353	0.96
5	23	1e-05	0.00028	20.9	0.4	1	23	360	383	360	383	0.98
6	23	0.00094	0.027	14.7	0.6	1	23	388	410	388	410	0.98
7	23	0.27	7.8	6.9	9.7	1	23	415	438	415	438	0.96
8	23	0.0021	0.061	13.6	0.1	1	23	445	467	445	467	0.97
9	23	4e-06	0.00011	22.1	2.2	2	23	474	495	473	495	0.97
10	23	2.8e-05	0.00079	19.5	0.2	1	23	504	526	504	526	0.98
11	23	0.00021	0.0059	16.7	0.4	2	23	530	552	529	552	0.95
12	23	0.066	1.9	8.9	0.4	2	23	562	584	561	584	0.91
13	23	0.00026	0.0074	16.4	0.0	2	23	591	612	590	612	0.97
14	23	0.13	3.8	7.9	1.4	1	23	619	642	619	642	0.93
15	23	0.00015	0.0042	17.2	0.3	1	23	648	670	648	670	0.96
16	23	0.00042	0.012	15.8	2.5	1	23	685	708	685	708	0.92
17	23	0.0011	0.032	14.5	0.1	1	23	714	736	714	736	0.98
18	23	4.4e-06	0.00012	22.0	0.4	1	23	741	763	741	763	0.97
19	23	4.3e-05	0.0012	18.9	0.9	2	23	771	792	771	792	0.98
20	23	0.016	0.46	10.8	1.2	1	23	798	821	798	821	0.96
21	23	0.0031	0.089	13.0	0.1	2	23	826	847	825	847	0.96
22	23	0.031	0.88	9.9	4.2	1	23	853	875	853	875	0.98
23	23	2.9	84	3.7	4.6	1	23	882	905	882	905	0.96

Sequence Information

Coding Sequence: ATGTCGGAAATCGTGCTCAGTTCCGACTCGGAAGACCAGAAGCCCAAGCTCGAGCCGGAGCCGTTGGATTGCGATGAGGTGCCCTCACCGGTTTACAATCTCCAGTCCGTGTTCGATTCGCTGGACTATCTGATCTCCCAGGATGGGTACCTGTGCGTGGCGTGTCCGGTTCACCGGAGGCGACCCTTCCGGGACATGAAGGACCTGCGTCGGCACATGATTGGCCACGTGAACGGTGGGCGAAGTTCGTCGACGTCGGAAATTCGTTGCACCCACTGTGGGTTGTGTTTTGGGTCGGTGCTGCAGCTGAGGAAGCACTTGCTGGCGGAGTTGGACCGGGAGTATGGGGGGCCGTCTAACTCTGGAGATGATCCGGCTTGTTTGGGCAATGAGTTTGAGGATAGTGGGGACGAGGAGGAAGTGATTAATTACGTCGTAAAGGGAGGTACGTTGACTTGTTCCGTTTGTGACGCCGAGTTTGGACTGGTTACGAGGTGGAACAAGGAAAAGTTCAAGATGCACGTCGGAAAGGATCACTGGAAGCCGGCGTTGTTCAGGTGTGATGAGTGTGGCAAGCGGTTCTGCGAGGAGGCAAGGTTGGAGAAGCATTTGAAGAAGCACGCTTTAGTTATGAGCGTTGGTTGGATGGGAACggaaccgacgacgacgacctgcGAGGTTCAAATTGACGCTGAAGACGCAATGAAGGATCCCGTTGATATCCAGGATGAGCTGCTACCTCAACCGGAAGTTTTGATCAAAACGGAACCGGAAGAAAATGAGCAGCCTAGTGCGATCATCATTCAACCGGCAGAATCATCCGAGAGTTCCGAATCGGAATCCTCCTCCGAAGACGACAAAACCGACAAGCCCGTCTTCACCAGCAAAAAGAAACAGGCCAAAGCCGACCGAATAGCGCGCAAGGAAGCTCTCCTGAAGACCGCCGTGCGCAAAATCTCCGACGGCACCGACGGCAGCCCCATCATCCTGGCCTGCAACATCTGCGACGAAGGCTTCCTCAAGCAGGACCTGCTCGATCGCCACATGGCCACCAAGCACGACGACCGCGACCGTCCCTTCCGCTGCGAGAAATGCCCCAAAACGTACATGAGCAACGCGAACCTGCAGGAGCACGTCCGGATGGTGCACGAGGGCGTCAAGTTCACCTGCGACCAGTGCAACATCCAGCTGGGCTCCAAGAGTTCCTGGAAGCGGCACATGCGGGGTCACTCCGAGAAGGGACACTGCTGCGACATTTGCCAGGAAAAGTGCTCGTCCCACTCGACGCTGATGACGCACAAGCGACGGGTGCACGAGAACTCGACGAAGAACTTTATCTGCGTGGACTGCGGGAACACGTTCGACAACGGGTCGGCGCTCCGGGACCACCGGGTCACGCACACGTCCGAGCGCAAGTGGGAGTGCACGACGTGCGGCATGAAGTTCAAGCGGAATCACAATTTGATAAGCCACCAGAGGGTCCACGCCGCGGGCCGCCCAGTCGTAACGTTCAAGTGCCAGgagtgcgacgaagagttcacCACCAAGGGCGCGTTGGCAGCGCACAAATCGTCCCACGGCCGCATCACCTGCCGGCTGTGCGAGCAAACGTTCAACGACCAGGCCGAACTGATGAGGCATCGCCGCGAGGATCACAAAATAACCAAACGCGACCCGGGCGTAACGTGCCGCACCTGTCACCAGCGGTTCGCCGATCAGGGCGAGATGTTGGAGCACCGAGCGGAGGCTCACCCGATGACAAATCCGATGGAGTGTGAGGTTTGCAAGTCCGTGTTTGGATCGGCGTCGGCACTGCGGGCTCACATGCGGGGACACGCGCCGAAGACTCGCTCCCACGACTGTCCCAACTGTGACGAGAGTTTCATCTGTGCGTTGATGCTGCAAACTCACATCAAAGAAACCCATCCGGATATGAAGAACCACGTTTGTGACCTGTGCGGCCGCGGCTATCCGACGAGGAAGCAGCTGTTGGCGCACATGGGTCGTCACCGGAATCCGAACCGCGAACGCGCCTCCAACACCCCTGGACAGTACATGTGCCACATCTGCGGCAAAGAGTTCAACTTGCGGGCATCGTTCAAACGCCACGTGTTCAACAACCACACCAACGCGCGTGACTTCAAGTGCGCCGTTTGCGACAAGCAGCTGGTCTCGGCCGAGGGCCTCAAGCTACACCTCAAGAGTCACGACGAGCAGCACTTTATGTGCTCGACCTGCGGCAAAGGATTCTCCCAACCGTACAGACTCCGCGCGCACATGCTACTGCACGAGCGTGAACTCGCCGAAGAGCGCTGCCCAATCTGCAATCGCGCCTTCCGCGACAAGAAAAAGCTCGACCTCCACATCAAGTCGCACACCGGCGAGACCGAGTTCAGCTGCACGCCCTGCCAGCGCTTCTTCGCCTCCGACAAGCTGCTCCAGAAGCACATCCAGCGAATGCACCAATCGTCCACGCCCTGTCCAGTGTGCGCGAAGGTCTTCCCCACCGAAGCCAAGATGAGAAACCACAGCCGCATCCACGACAATCCGACGTTCTTTGAGTGTCCGACCTGTTACACGTGCATCAAGGAGAAAAAGCACTTTGAAGCGCATATGAAGGGGCACCTGCAGGGTGGAGTTCGATTCACGTGTCGGTTCTGTCCGCTGACGTTCTCGCTGGCCAAGTCGTGTCGGAATCACGAGCGGAGATTCCACGTGGAGCTGGTAGGGGAAGCGGTGGGGGCTGGGGAAGGGGCGAGCGGGGAGAAGCCGGccaagaagaagaagcggaCGATGAAGGAGGAGGAAGACGGGTTTGCTGCGGACGGAATGATGGACGATCCGCTCGGGATGATGGACTTTACGATGGGCCAGCGTGAGGATGACGTTAGTGTAGGTTGA
Protein Sequence: MSEIVLSSDSEDQKPKLEPEPLDCDEVPSPVYNLQSVFDSLDYLISQDGYLCVACPVHRRRPFRDMKDLRRHMIGHVNGGRSSSTSEIRCTHCGLCFGSVLQLRKHLLAELDREYGGPSNSGDDPACLGNEFEDSGDEEEVINYVVKGGTLTCSVCDAEFGLVTRWNKEKFKMHVGKDHWKPALFRCDECGKRFCEEARLEKHLKKHALVMSVGWMGTEPTTTTCEVQIDAEDAMKDPVDIQDELLPQPEVLIKTEPEENEQPSAIIIQPAESSESSESESSSEDDKTDKPVFTSKKKQAKADRIARKEALLKTAVRKISDGTDGSPIILACNICDEGFLKQDLLDRHMATKHDDRDRPFRCEKCPKTYMSNANLQEHVRMVHEGVKFTCDQCNIQLGSKSSWKRHMRGHSEKGHCCDICQEKCSSHSTLMTHKRRVHENSTKNFICVDCGNTFDNGSALRDHRVTHTSERKWECTTCGMKFKRNHNLISHQRVHAAGRPVVTFKCQECDEEFTTKGALAAHKSSHGRITCRLCEQTFNDQAELMRHRREDHKITKRDPGVTCRTCHQRFADQGEMLEHRAEAHPMTNPMECEVCKSVFGSASALRAHMRGHAPKTRSHDCPNCDESFICALMLQTHIKETHPDMKNHVCDLCGRGYPTRKQLLAHMGRHRNPNRERASNTPGQYMCHICGKEFNLRASFKRHVFNNHTNARDFKCAVCDKQLVSAEGLKLHLKSHDEQHFMCSTCGKGFSQPYRLRAHMLLHERELAEERCPICNRAFRDKKKLDLHIKSHTGETEFSCTPCQRFFASDKLLQKHIQRMHQSSTPCPVCAKVFPTEAKMRNHSRIHDNPTFFECPTCYTCIKEKKHFEAHMKGHLQGGVRFTCRFCPLTFSLAKSCRNHERRFHVELVGEAVGAGEGASGEKPAKKKKRTMKEEEDGFAADGMMDDPLGMMDFTMGQREDDVSVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400802;
90% Identity: iTF_00400802;
80% Identity: -