Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:216190057-216196407[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.88 27 6.0 0.3 8 23 63 78 52 78 0.87

2 23 0.015 0.47 11.5 0.8 2 20 91 109 90 111 0.94

3 23 6.1e-05 0.0019 19.1 2.7 1 23 187 209 187 209 0.99

4 23 0.017 0.51 11.4 0.1 3 23 334 355 332 355 0.96

5 23 1.7e-05 0.00052 20.8 0.4 1 23 362 385 362 385 0.98

6 23 0.0016 0.049 14.6 0.6 1 23 390 412 390 412 0.98

7 23 0.46 14 6.9 9.7 1 23 417 440 417 440 0.96

8 23 0.016 0.5 11.4 0.1 1 23 447 469 447 469 0.97

9 23 1.4e-05 0.00042 21.1 1.4 2 23 476 497 475 497 0.97

10 23 4.7e-05 0.0014 19.4 0.2 1 23 506 528 506 528 0.98

11 23 0.00035 0.011 16.7 0.4 2 23 532 554 531 554 0.95

12 23 0.11 3.4 8.8 0.4 2 23 564 586 563 586 0.91

13 23 0.00044 0.014 16.4 0.0 2 23 593 614 592 614 0.97

14 23 0.22 6.9 7.9 1.4 1 23 621 644 621 644 0.93

15 23 0.00025 0.0078 17.1 0.3 1 23 650 672 650 672 0.96

16 23 0.00071 0.022 15.7 2.5 1 23 687 710 687 710 0.92

17 23 0.0019 0.058 14.4 0.1 1 23 716 738 716 738 0.98

18 23 7.4e-06 0.00023 22.0 0.4 1 23 743 765 743 765 0.97

19 23 7.2e-05 0.0022 18.8 0.9 2 23 773 794 773 794 0.98

20 23 0.027 0.83 10.7 1.2 1 23 800 823 800 823 0.96

21 23 0.0048 0.15 13.1 0.1 2 23 828 849 827 849 0.96

22 23 0.053 1.6 9.8 4.2 1 23 855 877 855 877 0.98

23 23 7.7 2.4e+02 3.0 4.8 1 23 884 907 884 907 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.88	27	6.0	0.3	8	23	63	78	52	78	0.87
2	23	0.015	0.47	11.5	0.8	2	20	91	109	90	111	0.94
3	23	6.1e-05	0.0019	19.1	2.7	1	23	187	209	187	209	0.99
4	23	0.017	0.51	11.4	0.1	3	23	334	355	332	355	0.96
5	23	1.7e-05	0.00052	20.8	0.4	1	23	362	385	362	385	0.98
6	23	0.0016	0.049	14.6	0.6	1	23	390	412	390	412	0.98
7	23	0.46	14	6.9	9.7	1	23	417	440	417	440	0.96
8	23	0.016	0.5	11.4	0.1	1	23	447	469	447	469	0.97
9	23	1.4e-05	0.00042	21.1	1.4	2	23	476	497	475	497	0.97
10	23	4.7e-05	0.0014	19.4	0.2	1	23	506	528	506	528	0.98
11	23	0.00035	0.011	16.7	0.4	2	23	532	554	531	554	0.95
12	23	0.11	3.4	8.8	0.4	2	23	564	586	563	586	0.91
13	23	0.00044	0.014	16.4	0.0	2	23	593	614	592	614	0.97
14	23	0.22	6.9	7.9	1.4	1	23	621	644	621	644	0.93
15	23	0.00025	0.0078	17.1	0.3	1	23	650	672	650	672	0.96
16	23	0.00071	0.022	15.7	2.5	1	23	687	710	687	710	0.92
17	23	0.0019	0.058	14.4	0.1	1	23	716	738	716	738	0.98
18	23	7.4e-06	0.00023	22.0	0.4	1	23	743	765	743	765	0.97
19	23	7.2e-05	0.0022	18.8	0.9	2	23	773	794	773	794	0.98
20	23	0.027	0.83	10.7	1.2	1	23	800	823	800	823	0.96
21	23	0.0048	0.15	13.1	0.1	2	23	828	849	827	849	0.96
22	23	0.053	1.6	9.8	4.2	1	23	855	877	855	877	0.98
23	23	7.7	2.4e+02	3.0	4.8	1	23	884	907	884	907	0.96

Sequence Information

Coding Sequence: atgtcgGAAATCGTACTCAGTTCCGACTCGGAAGACCAGAAGCCCAAGCTCGAGCCGGAGCCGCTGGATTGCGATGAGGTGCCCTCACCGCCTCCGGTTTACAATCTCCAGTCCGTGTTTGACTCGCTGGACTATCTGATCTCCCAGGATGGGTACTTGTGCGTGGCGTGTCCGGTTCACCGGAGGCGACCCTTCCGCGACATGAAGGACCTGCGTCGGCACATGATTGGCCACGTGAATGGTGGGCGAAGTTCGTCGACGTCGGAAATCCGTTGCACGCACTGTGGGTTGTGTTTTGGGTCGGTGTTGCAGTTGCGGAAGCACTTGCTGGCGGAGTTGGATCGGGAGTATGGGGGGCCGTCTAACTCCGGAGATGACCCGGCTTGTTTGGGGAATGAGTTCGAGGATAGCGGGGACGAGGAGGAAGTGATTAATTACGTCGTGAAGGGAGGTACGTTGACTTGTTCGGTTTGTGACGCCGAGTTTGGACTGGTTACGAGGTGGAACAAGGAAAAGTTCAAGATGCACGTCGGGAAGGATCACTGGAAGCCGGCGTTGTACAAGTGTGAAGAGTGCGGCAAGCGGTTCTGCGAGGAGGCAAGGTTGGAGAAGCACTTGAAGAAGCACGCTTTAGTTATGAGCGTTGGTTGGATGGGGACGGAACCGACGACAACAACCTGCGAGGTTCAAATTGACGCTGAAGACGCTATGAAAGATCCCGTTGATATCCAGGACGAGCTGCTACCTCAACCGGAAGTTTTGATCAAAACGGAACCGGTAGAAGACGAACAACCTGGTGCGATCATCATCCAACCGGCAGAATCATCCGAGAGTTCCGAATCGGAATCCTCCTCCGAAGATGACAAAACCGACAAGCCCGTCTTCACCAGCAAGAAGAAACAGGCCAAAGCCGACCGAATCGCGCGCAAGGAAGCCCTCCTGAAGACCGCCGTCCGCAAAATCTCTGACGGCACCGACGGCAGCCCCATCATCCTGGCCTGCAACATCTGCGACGAAGGCTTCCTCAAGCAGGACCTGCTCGATCGGCACATGGCCACCAAGCACGACGACCGCGACCGTCCCTTCCGCTGCGAGAAATGCCCCAAAACGTACATGAGCAACGCGAATCTGCAGGAGCACGTCCGGATGGTGCACGAGGGCGTCAAGTTCACCTGCGACCAGTGCAACATCCAGCTGGGCTCCAAGAGTTCCTGGAAGCGGCACATGCGAGGTCACTCCGAGAAGGGCCACTGCTGCGACATTTGCCAGGAAAAGTGCTCGTCCCACTCCACGCTGATGACGCATAAGCGACGGGTGCACGAAAACTCGACGAAGAACTTTATCTGCGTGGACTGCGGGAACACTTATGACAACGGGTCGGCGCTAAGGGATCACCGGGTCACGCACACGTCGGAGCGCAAGTGGGAGTGCGCGACGTGCGGCATGAAGTTCAAGCGGAATCACAATTTGATAAGCCACCAGAGGGTCCACGCCGCGGGTCGCCCAGTCGTGACGTTCAAGTGCCAGGAGTGCGACGAAGAGTTCACCACCAAGGGCGCGTTGGCCGCGCACAAATCGTCCCACGGCCGCATCACCTGCCGGCTGTGCGAGCAAACGTTCAACGACCAGGCCGAACTGATGAGGCATCGCCGCGAGGATCACAAAATTACCAAGCGCGACCCGGGCGTAACGTGCCGCACCTGTCACCAGCGGTTCGCCGATCAGGGCGAGATGCTGGAACACCGAGCGGAGGCTCACCCGATGACAGATCCGATGGAGTGTGAGGTTTGCAAGTCCGTGTTTGGATCGGCGTCGGCACTGCGGGCTCACATGAGGGGACACGCGCCGAAGACTCGCTCCCACGACTGTCCCAACTGTGACGAGAGCTTCATCTGTGCGTTGATGCTGCAAACTCACATCAAAGAAACCCATCCGGATATGAAGAACCACGTTTGTGACCTGTGCGGCCGCGGCTATCCGACGAGGAAGCAGCTGTTGGCGCACATGGGTCGTCACCGGAATCCGAACCGCGAACGCGCCTCCAACACCCCTGGACAGTACATGTGCCACATCTGCGGCAAAGAGTTCAACTTGCGGGCATCGTTCAAACGCCACGTGTTCAACAATCACACCAACGCGCGTGACTTCAAGTGTGCCGTTTGCGACAAGCAGCTGGTCTCGGCCGAAGGCCTCAAGCTACACCTCAAGAGTCACGACGAGCAGCACTTTATGTGCTCGACCTGCGGCAAAGGATTCTCCCAACCGTACAGACTCCGCGCGCACATGCTGCTGCACGAGCGTGAACTCGCCGAGGAGCGCTGCCCAATCTGCAATCGCGCCTTCCGCGACAAGAAAAAGCTCGACCTCCACATCAAGTCGCACACCGGCGAAACGGAGTTCAGCTGCACGCCCTGCCAGCGCTTCTTCGCCTCCGACAAGCTGCTCCAAAAGCACATCCAGCGAATGCACCAATCGTCCACGCCCTGTCCAGTGTGCGCGAAGGTCTTCCCCACCGAAGCCAAGATGAAGAACCACAGCCGCATCCACGACAATCCGACGTTCTTTGAGTGTCCGACCTGTTACACGTGCATCAAGGAGAAGAAGCACTTTGAAGCGCACATGAAGGGGCACCTGCAGGGTGGAGTTCGATTCACGTGTCGGTTTTGCCCGCTGACGTTCTCGCTGGCCAAGACGTGTCGGAATCACGAGCGGAGATTCCACGCGGAGCTGGTAGGGGAAGCGGTGGGGGCTGGGGAAGGGGCGAGCGGGGAGAAGCCGGCCAAGAAGAAGAAGCGGACGATGAAGGAGGAGGACGACGGGTTTGCTGCGGACGGATTGATGGACGATCCGCTCGGGATGATGGACTTTACGATGGGCCAGCGAGAGGATGACGTTAGTAGCCACTACGAAAAAAAGCAGCAGTTGGAATCCATCTTAGGTTCAACGAAGGACGACTTTAGGAAAAACCGGCATCTACAAGGTTTCCTGCAGTTACGATACGAGCTACATCGGACAAACTAA
Protein Sequence: MSEIVLSSDSEDQKPKLEPEPLDCDEVPSPPPVYNLQSVFDSLDYLISQDGYLCVACPVHRRRPFRDMKDLRRHMIGHVNGGRSSSTSEIRCTHCGLCFGSVLQLRKHLLAELDREYGGPSNSGDDPACLGNEFEDSGDEEEVINYVVKGGTLTCSVCDAEFGLVTRWNKEKFKMHVGKDHWKPALYKCEECGKRFCEEARLEKHLKKHALVMSVGWMGTEPTTTTCEVQIDAEDAMKDPVDIQDELLPQPEVLIKTEPVEDEQPGAIIIQPAESSESSESESSSEDDKTDKPVFTSKKKQAKADRIARKEALLKTAVRKISDGTDGSPIILACNICDEGFLKQDLLDRHMATKHDDRDRPFRCEKCPKTYMSNANLQEHVRMVHEGVKFTCDQCNIQLGSKSSWKRHMRGHSEKGHCCDICQEKCSSHSTLMTHKRRVHENSTKNFICVDCGNTYDNGSALRDHRVTHTSERKWECATCGMKFKRNHNLISHQRVHAAGRPVVTFKCQECDEEFTTKGALAAHKSSHGRITCRLCEQTFNDQAELMRHRREDHKITKRDPGVTCRTCHQRFADQGEMLEHRAEAHPMTDPMECEVCKSVFGSASALRAHMRGHAPKTRSHDCPNCDESFICALMLQTHIKETHPDMKNHVCDLCGRGYPTRKQLLAHMGRHRNPNRERASNTPGQYMCHICGKEFNLRASFKRHVFNNHTNARDFKCAVCDKQLVSAEGLKLHLKSHDEQHFMCSTCGKGFSQPYRLRAHMLLHERELAEERCPICNRAFRDKKKLDLHIKSHTGETEFSCTPCQRFFASDKLLQKHIQRMHQSSTPCPVCAKVFPTEAKMKNHSRIHDNPTFFECPTCYTCIKEKKHFEAHMKGHLQGGVRFTCRFCPLTFSLAKTCRNHERRFHAELVGEAVGAGEGASGEKPAKKKKRTMKEEDDGFAADGLMDDPLGMMDFTMGQREDDVSSHYEKKQQLESILGSTKDDFRKNRHLQGFLQLRYELHRTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401909;
90% Identity: iTF_00401909;
80% Identity: -