Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: -
Assembly: GCA_015732765.1
Location: NC:160177463-160194993[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.5e-10 2.6e-08 33.7 0.0 3 85 559 638 557 643 0.87

2 3 2.4e-13 4.4e-11 42.7 0.4 9 101 699 794 693 800 0.87

3 3 0.0091 1.6 8.6 0.4 58 107 785 832 768 835 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.5e-10	2.6e-08	33.7	0.0	3	85	559	638	557	643	0.87
2	3	2.4e-13	4.4e-11	42.7	0.4	9	101	699	794	693	800	0.87
3	3	0.0091	1.6	8.6	0.4	58	107	785	832	768	835	0.88

Sequence Information

Coding Sequence: atgtCTACAACAATCGGGAATCACGAGTACGAGTGTACGAAAAAGTGCCGGCTGCCGAGCCACGGCAATGCCATCACGGCGGCCCTCACAAAGCGGGCCATCTCGGACGAGTTGCTGGCCGCGTACGTCGCCAAACTGTGCCGGAACTTTGCCGAGATTCTGGACGATCAGGGACGAAGTGCACTTCACTTGGCGGCCTCCGTCGGACGGTACGCGATTGCCGAGTGGCTCATCAATCATGGGGCCAGCATCACGCTCAAGGACAGAGAATCTGGCCACACGGCACTGCATCGGGCCATGTACTACGGGTGTGTTGGAGTGGCCGTGGTGCTGCTAAAGCATGGGGCCGTGATCGATGTGCCGGATGAGGACTTTGTCAACCCGTTGCAGCTGTGCAGTAACGTTCACAAGGACAGAGACAACGGCATCGGCCACGAGATCATGGTGTGGGGCAAAAATCGCAACTACAACCTCGGAGTCGGCAACGTCGAGGGCAAAGACACGCCCGACTTCATCGACTTCTTCCGCAAAAACCGCATCTCGATCGAACGGATGTCCATCAACGCGTACCACAGTGTATTCTTGGGCCGGGACGGGGAGGTTTACGCAACGGGGCACGGGATGGGCGGTCGGCTGGGAAATGGCGCAGAACACACGGTGGTGCATCCGATCCGGATCGCCGTTCAGACGCGGGGCGCCGAGGAACGGATCGTGGACGTTAGCACCGGGAAACATCACACGCTACTGCTGTCCAGTAGTAATTGTATTTATGCATGTGGAGACAACAATCACTGCCAGTTAGGAATTAAGCCACCTCCAGAAAAGCAGCTTACATTTAAGGAAATTGGCGGATTGCACAATTTTGCCGACAAGAAAATCAAACGCATAATCGCCAAAGACTTCCACTCGATCGCGGTCTGCGACGAGGACGTCTTCGTTTGGGGTCTCAACGTGGGCCAGTTCGGCATGAAGAAGGAGCAAAACCCCGTTCTAACACCAAAAGCAATTTCCCTCCTCCCGGACGTGACAAACAAGCAAGATAAACCGGTCGCGATCGCCACCGACATCAAGCTAGTTGAATCAAGCAACGCCGCGATCGTCGTCTACACCAAAAGCAGCAATCTGTACATCTTCAACAACTTCAAACGGCGAACGTACAAAAATCCGCTGATGGAAAAGTTTGAGTGCATTTCCGTGTCCGGAGGGGAACTGGTCACCAAAAAGGAGGACGTCTCGAAGCAGGGCAAACAGCTGCGCATTCTGGCGTTCACCGTGTCCCGCAATATCTACATCTGGTACGAGGATTGTGGTCAGTTTGTGCGCTGTGTGTTTGCCCAGTCGAGGAATCTGGAGATTGAGAAGATCGTGTGGTGTAACAACCAtgcgctggtgctgctgctggggaATTTGTACCACGGGACGATTACGCACAAGTTGAACGCGCAGGCGGTTACTCAGATTAGTGAGTATACGGAGACGTACGCGAAGAAGGAGATGAGCACCACGAACAAGACGAGGATCGAGCTGAAGCGGATCAAGGGGCTGAACAATGTGGTGGACTTTGTGTGCGACGATGAGGGGGAGAACTTTGCGGTGTTGTTGGAAAACAGCCGCCGCTACTTCAACGTGCCCGAGCTGGTCGAGTCCAACTACGACTTTGGCACGCTTCTGGCCGAATCCCACGAGGAGGACGGCATCCACGACGTGGTGTTCCGCGTGGACTATCAAACCTTTCCGGCGCACCGCTTCGTCATCTACCACCGGTGTCGCCACCTGCGGAAACTGCTCGAAAAGCATCCCGAGCAGCGGGAGTTTTCGCTGGCGGGATACGAGGGGTTGGCGGCGCCGATTTTCGAGCTGATTCTTCGGTACATCTATGGGAACGAGCTGATCTCGAAGGAGGACGTGGAGGTGCTGGTGCGGAGGCTTCAACCGGGGGTGGAGGTGAATGGGGAGTCGGTGGACGGGATGGTGGCGCGGTTGAAAAAGGTGCTTAAGCAGCTGGACATTGGCGGGTTGGGTGAGGCGTTGAAGAAATCTTCCGAGGAGTTGGAGATCGCGGAGTTTCCCAAGCTGCCAAGGGACTCGTACCCTGAACTGAGGGACGTGACGATCAAGCTGCAGGGCAATCAGGAAATTCGTGCTCACAAGTGCGTGTTGACGTCCAGGTTGGACTACTTCAAGCTGATGTTCAGCCAGACTTGGGCGGAGAGCAAATCGGTCAACCTGACGACGGTCCCCCTCGAGTACATGGACACGATCGTGGACTTCCTGTACGACAACGACTATGAGCGGGTGCGCGATCAAAAGTATTCCGAAAGCTACCTCTTCCAGATGCTCACGCTGTGCGATCAGTTCTTCATCGACGAGTTGAAGTCGCTGTTCGAGGTGGTGATCGCCGATCGGATCAACCTGCGCAACGTCGGCGAGCTGTTGGAGTTTGCGCTGCAGTACAATTGCCACGTGCTGAAGGAGTTGTGCATGCAGTTTATCGCCGTCAATGCGGCCAAGATCTTGGAGTTGCGATCGCTGGAGGGGTGCGAGCCGGCGGTGCTGGAGATGGTTGACGAGTTTTATAGGGAGTTTTACAAGCTGGCGGATTATCGGATAATTACGCCTTCGGCGGATGCCGTTGACGATGAAGAGTTGGTGATGTTTGTGGACAATTTTAGCGTAGATTTAAACGAAAAAGCTAGCGAGATCGCGGCGGTGAGTAAGGCGAAGACCCCCAAGGGGAAGATCACTCCAAAGAGTACGAAGTTGCAGCAGGAGAAGCGAAATTACGAGAAGGAAGCGATGGATTACATTCGGAATTTGTCGTTTGAAGAGATTCCGATTGTTAAAAGTGAAGAGAAAAAAGTAACAGGTGTAGAAAATGGTCACGACTTGAAAACCGAGAAAGAGGTGAAGAATTGGCAGAAGGTCGTCGACAAGAAAGACCCAAAAAAGAAGCCCTTCACAACAGCGCTCAAAGTGAACGAAATAATCAAAAGTGAAACCCGCGGTCAGGAAAACTTCTCCAACCTAAAATCCCTCCTCGAAAAGACGCCTTCCCCAGGTCAGGAACCCGATCCGACCGGTTACGACTCCGGTTACAACAGTGCCCGGCTCAACACCTTCAACCTGAGCGACTTCGCCATCCAAAAGCCAAAACTGTCCCAAAAGCAACGCAAACGACTGTCTTCCACCTCGGAACGGCCCAAAGAAGCCGTCCAAGTCACGACCCCAGACGCCACCCCGCAACCCGCCAACCCCTGGAAGAACGTCAACAACTCCGCCGCTGACATGTTCAAATCAGAACCAATCCCCTTCCCGTCGTCGCCTCACGGCGATCGCAAAATCTCCACCAGCTTCGACCAAGCCACCTCCCCTCTATCCAACTCTCTACCTCGCGCCACAGCCGCAAAATCCCCCGCTCAACCGACGACCGTCAAGACGGTGGTGGCCAACGGCCACAAAAAAGCCCAAAAGGAAGAGTTCACCAAGATCCTGGAGGACGAGCGCCGCCAGAAGCAGTACTACGAAAAGATCAAATCGAAGTCGCTCGTGCACACGCAGATTGAGGAGCGGGCGATCGAGGAGTTGAGGAGGTTCTACAACGCGGACAGTGTGTACGACGAGAACATTACGATTGAGCGGCACAGGCCGCATCAGGCGCCGAGTGCGGTGTGGCAGTATCAGTAG
Protein Sequence: MSTTIGNHEYECTKKCRLPSHGNAITAALTKRAISDELLAAYVAKLCRNFAEILDDQGRSALHLAASVGRYAIAEWLINHGASITLKDRESGHTALHRAMYYGCVGVAVVLLKHGAVIDVPDEDFVNPLQLCSNVHKDRDNGIGHEIMVWGKNRNYNLGVGNVEGKDTPDFIDFFRKNRISIERMSINAYHSVFLGRDGEVYATGHGMGGRLGNGAEHTVVHPIRIAVQTRGAEERIVDVSTGKHHTLLLSSSNCIYACGDNNHCQLGIKPPPEKQLTFKEIGGLHNFADKKIKRIIAKDFHSIAVCDEDVFVWGLNVGQFGMKKEQNPVLTPKAISLLPDVTNKQDKPVAIATDIKLVESSNAAIVVYTKSSNLYIFNNFKRRTYKNPLMEKFECISVSGGELVTKKEDVSKQGKQLRILAFTVSRNIYIWYEDCGQFVRCVFAQSRNLEIEKIVWCNNHALVLLLGNLYHGTITHKLNAQAVTQISEYTETYAKKEMSTTNKTRIELKRIKGLNNVVDFVCDDEGENFAVLLENSRRYFNVPELVESNYDFGTLLAESHEEDGIHDVVFRVDYQTFPAHRFVIYHRCRHLRKLLEKHPEQREFSLAGYEGLAAPIFELILRYIYGNELISKEDVEVLVRRLQPGVEVNGESVDGMVARLKKVLKQLDIGGLGEALKKSSEELEIAEFPKLPRDSYPELRDVTIKLQGNQEIRAHKCVLTSRLDYFKLMFSQTWAESKSVNLTTVPLEYMDTIVDFLYDNDYERVRDQKYSESYLFQMLTLCDQFFIDELKSLFEVVIADRINLRNVGELLEFALQYNCHVLKELCMQFIAVNAAKILELRSLEGCEPAVLEMVDEFYREFYKLADYRIITPSADAVDDEELVMFVDNFSVDLNEKASEIAAVSKAKTPKGKITPKSTKLQQEKRNYEKEAMDYIRNLSFEEIPIVKSEEKKVTGVENGHDLKTEKEVKNWQKVVDKKDPKKKPFTTALKVNEIIKSETRGQENFSNLKSLLEKTPSPGQEPDPTGYDSGYNSARLNTFNLSDFAIQKPKLSQKQRKRLSSTSERPKEAVQVTTPDATPQPANPWKNVNNSAADMFKSEPIPFPSSPHGDRKISTSFDQATSPLSNSLPRATAAKSPAQPTTVKTVVANGHKKAQKEEFTKILEDERRQKQYYEKIKSKSLVHTQIEERAIEELRRFYNADSVYDENITIERHRPHQAPSAVWQYQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400736;
90% Identity: iTF_00400736;
80% Identity: -