Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:57351292-57427545[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0046 0.14 13.2 1.7 2 23 267 289 266 289 0.93

2 12 0.0049 0.15 13.1 0.1 1 23 297 319 297 319 0.98

3 12 0.05 1.5 9.9 4.9 1 23 327 349 327 350 0.94

4 12 10 3.1e+02 2.7 0.4 2 23 404 426 403 426 0.89

5 12 0.00015 0.0046 17.8 0.2 1 19 459 477 459 478 0.97

6 12 0.00045 0.014 16.3 0.2 1 23 490 512 490 512 0.98

7 12 0.00041 0.013 16.5 2.9 1 23 520 543 520 543 0.97

8 12 0.0021 0.065 14.2 0.1 2 23 550 571 549 571 0.97

9 12 2.2 68 4.7 0.9 2 22 582 602 581 602 0.94

10 12 0.044 1.3 10.1 0.1 2 23 611 632 610 633 0.93

11 12 0.014 0.43 11.6 3.4 1 23 639 661 639 661 0.98

12 12 8.5e-05 0.0026 18.6 1.3 1 23 667 690 667 690 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0046	0.14	13.2	1.7	2	23	267	289	266	289	0.93
2	12	0.0049	0.15	13.1	0.1	1	23	297	319	297	319	0.98
3	12	0.05	1.5	9.9	4.9	1	23	327	349	327	350	0.94
4	12	10	3.1e+02	2.7	0.4	2	23	404	426	403	426	0.89
5	12	0.00015	0.0046	17.8	0.2	1	19	459	477	459	478	0.97
6	12	0.00045	0.014	16.3	0.2	1	23	490	512	490	512	0.98
7	12	0.00041	0.013	16.5	2.9	1	23	520	543	520	543	0.97
8	12	0.0021	0.065	14.2	0.1	2	23	550	571	549	571	0.97
9	12	2.2	68	4.7	0.9	2	22	582	602	581	602	0.94
10	12	0.044	1.3	10.1	0.1	2	23	611	632	610	633	0.93
11	12	0.014	0.43	11.6	3.4	1	23	639	661	639	661	0.98
12	12	8.5e-05	0.0026	18.6	1.3	1	23	667	690	667	690	0.98

Sequence Information

Coding Sequence: ATGTCCCCCCCGTCATCGCACCTGGAAAGCTGCTTCACCTGTCTGCGCCGCACCGACAACTTCCTGTGCATCACGGAGCGGGACGAGGCCAGTGGCGAAGCCGTCGAGGCAATTTTCGCCAAACACTTTTGGTTTACCaaatgcGACTACCAAGATCGAACCGTTTGCACCAGCTGCTGGGAGAAGATTGACGAGTTTCACAAGTTTTACTGCGAGGTGGAACGGGTGCACGCGACGGAAGTGCTCGCTGAGATCAAAACggaagaggaggaggatgaCGAGGAGAATGCGTTGATGGTTGTGGAGTCGTCGGGGGAGCAGGGCGAACCGGTTTGTAAGGTCGAGCTTAAGCAGGAAGTAGCTGGAAATCCAGCTGAGCAGGAAGAGGGCCGTTCGGAAGATGGAGGGGACAATGCTCAGGCGAGTTCGCCGGAGGAGAATTCCGACGAGTCTGACTGGGATGTACCGCTGGCTCGGCGTGTGGCGAAAGTGAAGCAGAGGCGGAAACGGGCTTTGAAGAAGCGAGTTCAACGTGCCCGGTCGCGCAAGGAAAAGGCTGACAACGATGAGTTGAACGTCCTTATAAGGCAGCACATGGATATTACGTGCCACAAGTGTACGGAAGCCGGGACGGACAATGGGGAAACATTTGATTCTTTCTATCAGTTGAGGTTGCACTTTAAAAATCAGCACGACAACTCGTACGGTTACATTGTTTGTTGTAACCGAAAGTGGGTTTCGAAGCCCGGTTTGGCGGAACACTTGCAGAATCACGAACCAAGCAAGACAGACCACAGCCGGTGCGTGGAGTGCAATTGCATCTTCAAGGACAAGAGTAGCTACGCGAATCACATGTTTCTGGTGCACACGCCCGAGGAGCAGAAACAGTTCAAGTGCGATCGCTGTGCGAAGGCGTTCGCGGCGGAAGATCTGTTGAACAGTCATCTCAAGTGGCACGACGAGGTTGAGAAGAAGAATCATTACTGTGAAAAGTGCAACAAGTATTTCTTGAGCGCACGAAATCTGGAGAATCACATTTTTTCCCATCACAACGTTGGCGAGAGTTCGACCTCGATTCAACAACCCGCGGAAGCATTCGTCGAACAATCGACGGAAGAACCCGCACCGCAACTGGAACCGTCCAAGGGCAAACGAACCGCCGAGGATGTCGCCAAGGAGGACGACCTAATTCGGCAATTCATCTCGCTAAACTGTTCCAAGTGTGACTTTGTGGGGGAAACGTTCAACAAGCTGTCCTACCATGCCCTCAAGGCGCACAACATGAACACCCATGCGGTCATTTGCTGCGACCGCCGTTTTGGAAAACGGCAACGGCTGTACGAGCACTGTCTGCGGCACCTCAATCCGGACCACTTCAAGTGTGAACTGTGCGGTAAAACGTACGCCGACAGTTCCGGGCTGCAGATTCACAAGTGGTGGATCCACACCCCGGTCTCGGAGCGGCCCTTCAAGTGCGATATATGCGGAGCCGCTTTCGTCAAGGATTACCTCCTAAAGCAGCACACAAACTGGCACGTGAACAAGGAACGCAAGAAGTACTACTGCGAGTTGTGCAACAAGGCGTACTCGAACTCGCTCCAGCTGCGCGCGCATCACCAAAAGAAGCATGGCGCCGTGTGCGACTGGGTGTGCGATGTATGCGCGAAAGGATTCATCCATCGGGCACTGCTCGAAGAACACCGACTCACCCACACCGAAGAAGGACTCGCGAGTCTTAAGATCCAGTGCGAAAAATGTCAACGCTGGCTGATTAACAAGAAGAGCTATTTGAGGCATCGTAGGCGCTGCTACGACACGTCCGGTCCGATCAAGTGTGACATTTGTGGAAAAGAGTCAGCGAACGAGGCGGCCCTAGCCGGACACAAGAACTTCCATCACTCGAATCGTCCGATGTTCCGGTGCACGTTCTGCGGCAAGGAGTGCAAGACGCAGCTGCGGTTGAAGGAACACGAAGCTACCCACACCGGAGTGGTGCTCTACCAGTGCCCGTACTGTCCGCGAACGTCCAACTCCAGCTCCAATATGTACACGCACAAAAAGACCGCCCATCCGGAAAAGTGGCAGGAGGAGGCCGACGCGCGGTCCTACACGAGGTAG
Protein Sequence: MSPPSSHLESCFTCLRRTDNFLCITERDEASGEAVEAIFAKHFWFTKCDYQDRTVCTSCWEKIDEFHKFYCEVERVHATEVLAEIKTEEEEDDEENALMVVESSGEQGEPVCKVELKQEVAGNPAEQEEGRSEDGGDNAQASSPEENSDESDWDVPLARRVAKVKQRRKRALKKRVQRARSRKEKADNDELNVLIRQHMDITCHKCTEAGTDNGETFDSFYQLRLHFKNQHDNSYGYIVCCNRKWVSKPGLAEHLQNHEPSKTDHSRCVECNCIFKDKSSYANHMFLVHTPEEQKQFKCDRCAKAFAAEDLLNSHLKWHDEVEKKNHYCEKCNKYFLSARNLENHIFSHHNVGESSTSIQQPAEAFVEQSTEEPAPQLEPSKGKRTAEDVAKEDDLIRQFISLNCSKCDFVGETFNKLSYHALKAHNMNTHAVICCDRRFGKRQRLYEHCLRHLNPDHFKCELCGKTYADSSGLQIHKWWIHTPVSERPFKCDICGAAFVKDYLLKQHTNWHVNKERKKYYCELCNKAYSNSLQLRAHHQKKHGAVCDWVCDVCAKGFIHRALLEEHRLTHTEEGLASLKIQCEKCQRWLINKKSYLRHRRRCYDTSGPIKCDICGKESANEAALAGHKNFHHSNRPMFRCTFCGKECKTQLRLKEHEATHTGVVLYQCPYCPRTSNSSSNMYTHKKTAHPEKWQEEADARSYTR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402110;
90% Identity: iTF_00402110;
80% Identity: -