Basic Information

Insect
Culex pipiens
Gene Symbol
-
Assembly
GCA_016801865.2
Location
NC:21296898-21308116[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 5.4e-05 0.0017 19.2 2.1 2 23 220 241 219 241 0.98
2 10 0.00052 0.016 16.1 0.2 1 23 249 271 249 271 0.98
3 10 0.0071 0.22 12.6 0.3 3 23 310 330 310 330 0.98
4 10 0.00051 0.016 16.2 0.4 2 23 361 383 360 383 0.95
5 10 0.0047 0.15 13.1 2.0 2 23 399 420 398 420 0.97
6 10 0.00093 0.029 15.4 0.8 1 21 428 448 428 449 0.95
7 10 2.4e-05 0.00074 20.3 0.7 1 23 477 499 477 499 0.99
8 10 0.65 20 6.4 0.1 2 23 653 676 652 676 0.90
9 10 0.00072 0.022 15.7 0.2 1 23 684 707 684 707 0.98
10 10 0.0015 0.047 14.7 0.1 2 22 748 768 747 768 0.95

Sequence Information

Coding Sequence
ATGGAAAATCCACCATCTAGCCGGCAGAAACCTCCCCAGCTGGATGACTTTTGTCGCATTTGTCTGCTGCGGGAGCCATCGCTCCGTCCGCTGGCGGTCCCACTCTCCGGCGTTATGATTCCGGAGATGTTGTACAAGGTAACCGGCACGATGCTCAACTTGCAGGAACAGTTGCCGCGGGTCATTTGCGAGCGGTGCCTCGTGAAGCTTGAGCTAGCGTTCAGCGTCGCCGAGGAGTTCCGCCGGCAGGAGGAGAAGCTACGACTGTTTTGGTTTAAGGGGGGTGTGCTGGTGGATGAGTTGGTGGCGTACCAGCGGACGGAGGAGTCACGGATGAAGGGGCACTCGGAGGAAGTTATAGAGAGGTTGACGGTTGGCCGATTGGATCCGGTTGACAAAGATACGATTCTTAAGCAAGACCTGGAAGTAAAACAAGAAGCATCGGAATTTTGTATTGAGATCCTGTCGGATGATTCTGCGGACGAACAGCAGCAACCCGATGTTGGCGAGCCTCCGTCCCCAGCGGAATCCGAACTGGAACAGGACGATAATGTCAACGATTCGGATTACGTACCTGATGACATGGTCCAGCTCGATGAGGACGGTTACTCCGACTCTTCGCATGCCGATGTACCGAGACTTGGAAAAGAGGCAACGAAATGTCCGGTGTGCAGTAAAGAGTTTAGTACGACGTTGTCTTTGAAGCGCCATTACAGACGGCACGTTATCCGAGCGAAAGAGAAATTCAAATGCACAAAGTGCGATAAAGCATTAGCATCCGAACAAGAGCTGGAACTCCATCAATTGTCTCACTCAAACCCATTCAAGTCCCAACCACGCCTGCGAGCGCATCAGAAGATTTACGAGCAGCGGAAGGATCCGTTGCCGTCTCCATCCTTTACCGCAAAGAAGAAATTTTGGTCCTGGTGCAAGTTTTGTGGGAAGGGCTTTGGCCGGGAAGATCGTTTGGAGCAGCACGAAGCAACGCACGAAAAAGGGCGGTCCGACGGAAACGCCTCGGTAAACGTTTATCACAAGTTGGAGCAAATACTTGCGAAGCAGAGACAAAAGCAGCAAATGGAGTGCGAGTTTTGTCCAAGGACATTCCGGAACGAAACTGAACTGGCGCAACACTTGGAAAAGCGTCATAACGACCAGTTGTACGAAAAGTCTGACAACGCTGACGGTCGCCTAAAATGCTCCAGATGTGGACGAACATTCGAGAACGATTATAAATTCGGGATGCACATGAAGAAGCACGCAAACGTTGACAGTGGTAAATTCAAGTGCGTAAATTGTGACCACGCATTCGGAACCAAATTCGAACTGCTGAGACACATGCTCCGGTACGAAAAACAATCGGAGTGGCAAAAGGCTTGTGAGAAGATGACGCCCCCGCTCACGATCGACACAGGCGTAAAACCCTTCTTCAAGTGCCCCGTCTGTGACAACGTGTTCGTCTCGCGATCGAACTACTTCCAGCACGCGCAGACTCACACCGAGGCCTGGCCGAAAGTGCAAAGAAAGTCCAACTCGGTTGCGAAAGCAGAGTCATCAGGCGCCACGACGGTTCTGTTTTCGTCGCAGGAGAGCTACGAAATTCATCTGCAGCAGGGACATCGGGACGAAGGAGCACCTGGAGAGCCGACCAACCAAGAATCTGACCATCCCTCCGATCTACCCATCATTCGAGAAGTGGCGGGTTCTTACGTCAAGGAGGAAGTACCTATCGAAGAAAGTCACATTGCTCACGAGAACCTCCCAATGGACGAGTATGAGCGGGAACCGCCGAAACCGGAGCAAGTCGTTAACAAAATGGAAACCGATCACGACGAGGTCGATAACCTAGGTTCGGAATATGCGACCGAGTTTAGCATCGAAATGCTGTCGGATGATCCGGACGATGAAGCGCTCGAACCGCCCACCAGTGGCGCCGAGTCCACGTCCAAATCATGGAAGTGCAACATCTGTGGCATTGTAATCAACACGACAACGGACGCTTCCGTCACGAGGCACATGCTCATGCACGAAAACATCCAGAATGGGACGTACGAGTGTGAAGTTTGTAACAAGCGATATGGTTTCAACCCGGGCCTTCAGCAGCATAGACGAATTGTTCACAATTTGAAGCCACAAGCGTCGGATGATTCCTTTGAGTGTGAGCAGTGTAAGAAGTACATCAAGAAGACTAAGTACACCTTTCATCTCAGTTGTCATAGAAACATTAAGTTGCGTACTATCGTGTGCGAAAAGTGTGATAAGGCGTTTGGCGCGAAGCAATATCTGCAGAGCCACATGATGACAAGAGCGTGCGAAAAAGTCAGCCGAAGTCAGAGCCGGAACACGCTGTAG
Protein Sequence
MENPPSSRQKPPQLDDFCRICLLREPSLRPLAVPLSGVMIPEMLYKVTGTMLNLQEQLPRVICERCLVKLELAFSVAEEFRRQEEKLRLFWFKGGVLVDELVAYQRTEESRMKGHSEEVIERLTVGRLDPVDKDTILKQDLEVKQEASEFCIEILSDDSADEQQQPDVGEPPSPAESELEQDDNVNDSDYVPDDMVQLDEDGYSDSSHADVPRLGKEATKCPVCSKEFSTTLSLKRHYRRHVIRAKEKFKCTKCDKALASEQELELHQLSHSNPFKSQPRLRAHQKIYEQRKDPLPSPSFTAKKKFWSWCKFCGKGFGREDRLEQHEATHEKGRSDGNASVNVYHKLEQILAKQRQKQQMECEFCPRTFRNETELAQHLEKRHNDQLYEKSDNADGRLKCSRCGRTFENDYKFGMHMKKHANVDSGKFKCVNCDHAFGTKFELLRHMLRYEKQSEWQKACEKMTPPLTIDTGVKPFFKCPVCDNVFVSRSNYFQHAQTHTEAWPKVQRKSNSVAKAESSGATTVLFSSQESYEIHLQQGHRDEGAPGEPTNQESDHPSDLPIIREVAGSYVKEEVPIEESHIAHENLPMDEYEREPPKPEQVVNKMETDHDEVDNLGSEYATEFSIEMLSDDPDDEALEPPTSGAESTSKSWKCNICGIVINTTTDASVTRHMLMHENIQNGTYECEVCNKRYGFNPGLQQHRRIVHNLKPQASDDSFECEQCKKYIKKTKYTFHLSCHRNIKLRTIVCEKCDKAFGAKQYLQSHMMTRACEKVSRSQSRNTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00402018;
90% Identity
iTF_00402018;
80% Identity
-