Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:47558699-47565189[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0064 0.2 12.7 0.8 2 23 184 206 183 206 0.96

2 14 1.1 33 5.7 0.4 6 23 215 233 215 233 0.98

3 14 4.3 1.3e+02 3.8 0.4 1 21 245 267 245 270 0.88

4 14 0.014 0.42 11.7 0.2 1 23 278 300 278 300 0.93

5 14 0.00048 0.015 16.3 3.1 3 23 310 331 308 331 0.94

6 14 0.27 8.3 7.6 0.1 3 23 411 432 409 432 0.96

7 14 4.6e-05 0.0014 19.5 0.4 1 23 464 487 464 487 0.94

8 14 0.00016 0.0049 17.8 0.9 1 23 495 517 495 517 0.98

9 14 1e-05 0.00032 21.5 0.3 1 23 525 548 525 548 0.96

10 14 0.00011 0.0034 18.3 0.5 2 23 555 576 554 576 0.96

11 14 2.2 68 4.7 1.8 2 22 587 607 586 607 0.94

12 14 0.21 6.5 7.9 0.1 2 23 615 637 614 637 0.93

13 14 0.0027 0.082 13.9 0.8 1 23 643 665 643 665 0.93

14 14 0.0012 0.036 15.0 2.4 1 23 671 694 671 694 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0064	0.2	12.7	0.8	2	23	184	206	183	206	0.96
2	14	1.1	33	5.7	0.4	6	23	215	233	215	233	0.98
3	14	4.3	1.3e+02	3.8	0.4	1	21	245	267	245	270	0.88
4	14	0.014	0.42	11.7	0.2	1	23	278	300	278	300	0.93
5	14	0.00048	0.015	16.3	3.1	3	23	310	331	308	331	0.94
6	14	0.27	8.3	7.6	0.1	3	23	411	432	409	432	0.96
7	14	4.6e-05	0.0014	19.5	0.4	1	23	464	487	464	487	0.94
8	14	0.00016	0.0049	17.8	0.9	1	23	495	517	495	517	0.98
9	14	1e-05	0.00032	21.5	0.3	1	23	525	548	525	548	0.96
10	14	0.00011	0.0034	18.3	0.5	2	23	555	576	554	576	0.96
11	14	2.2	68	4.7	1.8	2	22	587	607	586	607	0.94
12	14	0.21	6.5	7.9	0.1	2	23	615	637	614	637	0.93
13	14	0.0027	0.082	13.9	0.8	1	23	643	665	643	665	0.93
14	14	0.0012	0.036	15.0	2.4	1	23	671	694	671	694	0.97

Sequence Information

Coding Sequence: ATGACCGAGGAAAGCCTGCTGCAGGACTGCCTCACCTGTCGGCGCAAGACGGAAACTTTCCTCCGAATTCGGAACGACATCGCCGATGACGAAGATACCGTCGAGTCCGTCCTCGCGAAGCACTTTTGGTTTGAGGCCATCCAGTACCGCGACCGGGTGCTGTGCACCAGCTGCTGGGAAAAGATCGACGAGTTTCACAAGTTTTACTGCGAGGTCGAGGAGCGATGGGGACTGCACGTGGAGGTCAAAACAGAACAGCTGGAGGAGGAGGGCGTTGCTTTTGATGTAGTTAAGGCTGAACGGTTGGAGTCGGATGGGGGAAGTTTTGGGGAGGATTCGGACGGAGATTTTGAGCCGGGTGAAGCGAAGATGGAACTTCCGGATGATTTTTCTGAGGATTCGGAAGAGGAGTCTACGACCCCAATAGCTAAGAGGAAACGGTCCGCGCGGGACGAAGGAACGGGTTCAGTGCGTAAAACAAGCTACGTCCGGTCGCACAAGCGAGCTAACCGGGAACGGAACGACCTGATTGCGAAATACGTCCAGCTTCAGTGTGACATTTGCAGCGAACGGTTCGCGACATTTTCCCGGCTGCTTCTACACTACAAACGGTCCCACGAAACGCAAGGGTACGTGACCTGCTGCGAGAAACCGTTCCACAAGCGGTCCGTACTTGTCGAACATCTCCGGAAGGTGCACGAATTTGTCGCCGGTGGCGATGACGAGTCTCAGTTCCGGTGTGAACTTTGCGAGCCGGTGAGGAACTTCAAGGACGAAGAGGGACTTCAGCTGCACAACGTGGTGTGTCACACGGCGGAGGGGGAGCGGATCTACAAGTGCGACCAGTGCGAGAAGGCGTTCGACAGCGAGTGGGCCCTGAGTGGACACAAGTACTGGCACCAGAACATTGAGAGCTTGAACATTTGCTGCGAAAAGTGCAATAAATATTTCAATTCCGCCCGCACGCTCAACACTCACATGCGTGCCTTCCACCCGGAAGGCACCACCACAACATCCGGAACATCCTTCTCGACGACGATGTCCACCGACGCCATCACTATGGCCGAACCAACACTCCCAGATCAGCTCATTGCCGGAGCTGCTCCGGAAGATTCCTTCAAAGCCCCAAGCCAATCGGCGCGAGCCACCTCAGCCACCCGGAAGGCGCCCAAATCCGCCGAAGAGCTGGCCCAAGAGGACGACCTGATTCGGCAGTTTTGCACGCTGCTCTGCGAAAGCTGTGACTTCGTTGCGGACAGCTTCTACGCCCTCGAGCGGCACTACAAGACGGAACACGACCAGCGCGGGTACGCCATCTGCTGTGGGCGAAAGTTTTGCAAGAAACGCCGCCTGTACGAGCACTGCCAACGGCACGTCAATCCGGACGCGTTCCGATGCGAAGTGTGCAACAAGTCGTTCACCGAGAGCGACGGGCTGGAGAAGCACAACAAGTGGGTCCACACGCCGGACTCGGAGAAGCCGTTCAAGTGTGAGATCTGCGACGCGGCGTTCTACAAGGACTATCTGCTGCGAAACCACATGAAGTACCACATCTCGATGGAGCAGAAGATTTTCAACTGCAAGGATTGCGACAAGTCCTTCGGCACGGCGGTCCTGCTGCGGGCGCACCAGCAAAACATCCACGGCGCCGCGTCCAGCTGGGTTTGCGACATCTGCGCCAAGGGGTTCGTGCACAAATCCCAGCTCGAAACGCACCGCCTCTCGCACTCCGAGGAGGGCGCGGCCAGCCTGAAAAAGCAGTGCGAACGGTGcaaaaagtggctcaaaaacaaGGACACGTACACGAACCACCTGAAGCGGTGCCTCGCCGGAGGTCCGGTTACGTGTGACATTTGCGGCAAGGAGGCGGTCAACGAGCTGGCACTGGCCTCGCACAAGCGATTCAACCACGAGGACAAACCGGCGTTCGCGTGCAGCTACTGTGGGAAGCAATTTAAGCGGCTGCTGCGGCTCAAGGAACACGAAGCGAATCATCGCGGCGAGTTGCTCTACTCGTGTCCGTACTGTCCGCGGCAGTGCAACTCCAGCTCGAACATGTACACCCACAAGAAGGTGGCCCACCCGGAGCTGTGGGCTGCCAAGGTGGCGGACAGGTACTACAAGCGATGA
Protein Sequence: MTEESLLQDCLTCRRKTETFLRIRNDIADDEDTVESVLAKHFWFEAIQYRDRVLCTSCWEKIDEFHKFYCEVEERWGLHVEVKTEQLEEEGVAFDVVKAERLESDGGSFGEDSDGDFEPGEAKMELPDDFSEDSEEESTTPIAKRKRSARDEGTGSVRKTSYVRSHKRANRERNDLIAKYVQLQCDICSERFATFSRLLLHYKRSHETQGYVTCCEKPFHKRSVLVEHLRKVHEFVAGGDDESQFRCELCEPVRNFKDEEGLQLHNVVCHTAEGERIYKCDQCEKAFDSEWALSGHKYWHQNIESLNICCEKCNKYFNSARTLNTHMRAFHPEGTTTTSGTSFSTTMSTDAITMAEPTLPDQLIAGAAPEDSFKAPSQSARATSATRKAPKSAEELAQEDDLIRQFCTLLCESCDFVADSFYALERHYKTEHDQRGYAICCGRKFCKKRRLYEHCQRHVNPDAFRCEVCNKSFTESDGLEKHNKWVHTPDSEKPFKCEICDAAFYKDYLLRNHMKYHISMEQKIFNCKDCDKSFGTAVLLRAHQQNIHGAASSWVCDICAKGFVHKSQLETHRLSHSEEGAASLKKQCERCKKWLKNKDTYTNHLKRCLAGGPVTCDICGKEAVNELALASHKRFNHEDKPAFACSYCGKQFKRLLRLKEHEANHRGELLYSCPYCPRQCNSSSNMYTHKKVAHPELWAAKVADRYYKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402012;
90% Identity: iTF_00402012;
80% Identity: -