Cpip008326.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NC:110044360-110045863[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.007 0.21 12.6 0.2 3 23 150 170 148 170 0.97 2 9 0.00011 0.0035 18.2 0.4 2 23 177 198 177 198 0.97 3 9 0.0017 0.053 14.5 4.2 1 21 204 224 204 226 0.95 4 9 5.6e-05 0.0017 19.2 1.8 1 21 233 253 233 255 0.95 5 9 2.4e-05 0.00073 20.4 0.3 1 23 261 284 261 284 0.96 6 9 9.6e-05 0.0029 18.5 0.4 3 23 292 312 290 312 0.96 7 9 5.5e-06 0.00017 22.4 3.1 1 23 318 341 318 341 0.97 8 9 0.0016 0.05 14.6 1.5 1 23 347 369 347 369 0.98 9 9 3.2e-05 0.00097 20.0 0.7 2 22 376 396 375 396 0.96
Sequence Information
- Coding Sequence
- ATGATGGACTTTTCCAACCGGTGCCGGGGCTGCTTATCGAACGATGAAGAAACCTTGCAACTTCTTGACGACCCCACCGTCCTGCTGTTTGAGGACTGCGTTAGAATCCAGATTTCCTCCGATGAACCAAAACTCCCAAAGCACATCTGCAGCACCTGCTACGGAAAGTGTTCCGCTTGGGCCAAATTTCGCCAGCAGTGCTGGGAAACGAACGAGCTGCTCAGTTTCCGGCTTGGCCACGAGCAGCTCGAAATAATCGGCTCGACGAGCAGCATTGAAAAGGAGGAAGTTCCGGAAACGGTTGAGGAGCCTTCTGTGGTGCGGATTGAAAATGCGGAAGTTGCGGTTGAGGATGGTTGTTCCGACGCGGTTTTCTCGCCCGATGAGGAGGATGAGCAGGTCTCCTCCGTTGAGGTGTACGAGATTAAGAGTGGTCGCGATATCGCCTGCACTCAATGTCCGATGCAGTTCCGCAGTATGGAGCGATTTGAAGCGCACTGGCGCACTCACCAGGGGTTGAAGGCGGAAGTTTGCAAGATTTGCAACGGTGAATTTAACAATGCCCGGGCGCTGCGTCGTCACATGTTGAAGCACGTGGAGGGGAAAAAGTTCACCTGCCAAGAGTGCGGCAAGAGTTACAAGTTTGCGACCTCGCTGACGCTGCACCGGAAGTGCCATCAGGACGGGCCGCGGCGGTTCGTTTGCGACCTGTGCGGGAAGGCGTTCGTGCGGGCGCACGGGCTGAAGAGTCACATGTCGTGCCACTCGACGGAGATGCCGTTTGAGTGCGGGGAGTGTGGGAAGCGGTTCAAGAACGAGATTATGTTGAGGAATCACGTGACGAGGGTTCACGAAGGGGTGAAACGGTTTGGGTGTTTGAGTTGTGGAAAGAAGTTTAAAACGGCGGCGGAGCTTAAAATTCACGAGAGGTCGCACACAAATTTGAAGCCGTTCAAGTGCAAAGAATGTGAAAAGAGTTATAAAACCCAGAGTCATCTGGCGGTTCACTTCCGGAACGCGCACACTTCGGAACGACCGTATGAGTGTGAGTTCTGCGGGTTGCGTTTTGGCCATAGCAAGGTGCTTAAAAGCcatcgattgatccacacgcaGGAGAAACCGTGGCAGTGCCAGGTTTGTAAGCAGAACTTCCGGCAGCAGGCGACGCTGAAGTCGCACATGCGAACTCGTTGTTCCGCAGGAGTTCAACCGGATAATGGGATGAATGTGGAGGAAGTGAGCAGCGTTGGGGAGGTAAGATCTGGAATCGATTTTGGCGTAATCGAGGTTATAGAATCTTCTCAGTAG
- Protein Sequence
- MMDFSNRCRGCLSNDEETLQLLDDPTVLLFEDCVRIQISSDEPKLPKHICSTCYGKCSAWAKFRQQCWETNELLSFRLGHEQLEIIGSTSSIEKEEVPETVEEPSVVRIENAEVAVEDGCSDAVFSPDEEDEQVSSVEVYEIKSGRDIACTQCPMQFRSMERFEAHWRTHQGLKAEVCKICNGEFNNARALRRHMLKHVEGKKFTCQECGKSYKFATSLTLHRKCHQDGPRRFVCDLCGKAFVRAHGLKSHMSCHSTEMPFECGECGKRFKNEIMLRNHVTRVHEGVKRFGCLSCGKKFKTAAELKIHERSHTNLKPFKCKECEKSYKTQSHLAVHFRNAHTSERPYECEFCGLRFGHSKVLKSHRLIHTQEKPWQCQVCKQNFRQQATLKSHMRTRCSAGVQPDNGMNVEEVSSVGEVRSGIDFGVIEVIESSQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00402008;
- 90% Identity
- iTF_00402008;
- 80% Identity
- -