Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:223586027-223696903[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 3.8e-05 0.0012 19.7 2.0 1 23 212 234 212 234 0.98

2 18 1.6 50 5.2 5.7 1 23 240 262 240 262 0.98

3 18 8.8e-07 2.7e-05 24.9 3.1 1 23 268 290 268 290 0.99

4 18 4.1e-05 0.0012 19.6 0.3 1 23 296 318 296 318 0.98

5 18 0.39 12 7.1 0.5 2 23 423 445 422 445 0.96

6 18 0.57 17 6.6 0.2 1 23 592 614 592 614 0.95

7 18 4.1 1.3e+02 3.9 0.3 1 23 624 646 624 646 0.89

8 18 0.0036 0.11 13.5 1.1 1 23 654 678 654 678 0.92

9 18 0.012 0.37 11.8 0.1 1 23 683 706 683 706 0.93

10 18 0.029 0.88 10.7 1.5 1 23 713 736 713 736 0.98

11 18 0.005 0.15 13.0 2.0 1 23 768 790 768 791 0.96

12 18 1.8 57 5.0 0.2 1 23 1001 1025 1001 1025 0.93

13 18 0.0046 0.14 13.2 0.2 2 23 1034 1056 1033 1056 0.96

14 18 0.012 0.36 11.9 0.1 1 23 1062 1084 1062 1084 0.98

15 18 0.5 15 6.8 2.6 2 23 1092 1113 1092 1113 0.96

16 18 3.2 97 4.2 1.4 2 23 1244 1265 1244 1265 0.95

17 18 0.0047 0.15 13.1 0.3 1 23 1275 1297 1275 1297 0.97

18 18 0.0037 0.11 13.5 1.6 1 23 1304 1326 1304 1326 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	3.8e-05	0.0012	19.7	2.0	1	23	212	234	212	234	0.98
2	18	1.6	50	5.2	5.7	1	23	240	262	240	262	0.98
3	18	8.8e-07	2.7e-05	24.9	3.1	1	23	268	290	268	290	0.99
4	18	4.1e-05	0.0012	19.6	0.3	1	23	296	318	296	318	0.98
5	18	0.39	12	7.1	0.5	2	23	423	445	422	445	0.96
6	18	0.57	17	6.6	0.2	1	23	592	614	592	614	0.95
7	18	4.1	1.3e+02	3.9	0.3	1	23	624	646	624	646	0.89
8	18	0.0036	0.11	13.5	1.1	1	23	654	678	654	678	0.92
9	18	0.012	0.37	11.8	0.1	1	23	683	706	683	706	0.93
10	18	0.029	0.88	10.7	1.5	1	23	713	736	713	736	0.98
11	18	0.005	0.15	13.0	2.0	1	23	768	790	768	791	0.96
12	18	1.8	57	5.0	0.2	1	23	1001	1025	1001	1025	0.93
13	18	0.0046	0.14	13.2	0.2	2	23	1034	1056	1033	1056	0.96
14	18	0.012	0.36	11.9	0.1	1	23	1062	1084	1062	1084	0.98
15	18	0.5	15	6.8	2.6	2	23	1092	1113	1092	1113	0.96
16	18	3.2	97	4.2	1.4	2	23	1244	1265	1244	1265	0.95
17	18	0.0047	0.15	13.1	0.3	1	23	1275	1297	1275	1297	0.97
18	18	0.0037	0.11	13.5	1.6	1	23	1304	1326	1304	1326	0.95

Sequence Information

Coding Sequence: ATGTCACGCAGGAAGCAGGCCAAACCGCGTGCGTTTAAACatgatgacgacgatgacGGACTGGTGGAAAATCGTGGCGAAGCCGGAGGACTGTTGGCCGTCAACGATAACAGCGAAAAGGAAAATGATATGCCAGACAATGACACcgacgccgacgacgacgacgacgaagagggTGAGGGGGAAGATGGGGAAGAGGAAGCTGACGAGGACGGGGCCGAAATGCTCGAGGATGGTGATGAGCCGGAAAATGGAGGTGACCCGATAAAGCACGAACTCTTTGACAATGATTCGATCAATTCCAACGATTACAACGACGATGATCTCACCTCGGAGAGCTTCTGTTCCGAACTCTACTCGTCGCACACGTCGTCCAGCTTTTCGCCGTCGATATCGGATGGCATGACGACGCCGAACTCGATAACCAACGACGGCGACCATCATCATCAACCCGGATCGGCCAACGGAGGCACAGCAGATTCCGAGCAGGCACCGGCTGGACAGGACAAACGTGGTGGCCATCAGCACCGACggcaccatcaccaccaccatcgGTCCTCCGCcgacaataataataaaataattaaaaataacaatcacacaaacagccacagcAAGAATAATGACGGCACTTATCGGTGTCAGTTTTGTGATAAAACGTTTCCCCGGCTCGGCTACCTGAAGAAGCACGAACAGAGCCATACCGAACATATGCCATTCAAGTGTGAATACTGCGCTCGTTTGTTCAAACACAAGAGGTCACGGGATCGTCATACCAAGCTGCATACGGGAGATCGGCGATACCGGTGCCCTCACTGCGAGGCGGCATTCTCCAGAAGTGATCACCTGAAGATCCACATGAAGACGCACGACAACCAGAAACCTTTCCAGTGTACGATCTGTAATCGGGGCTACAATACGGCGGCGGCCCTGACCAGTCACATGCAGAACCATAAGAAGCAGATTGCGCTGACCGGGAGTCCAAACCTGACGTACAGTCCTCGGTCAACCAGTTCGCTGTCGAGCAGTGCGTCGAATCCCAAGCGGAAATTTTCGCCGTACGAACAGAACCTGATGATGATCAATCGCTCCAAGTTGCTCAAATCTGGTGAACTCACTTGCATCTACTGCACGCGAACAGATTTCGCAAACCTGGAGCAGCTGGGAGCTCACGTACAAACCATGCACAGTAATCTACTGCTGAACGAGAACAATTTCCATCGAATGCCGACCTCGCCGGATGCCCTCCTTTCGTATCCGCCAATATCCTGCGAGTTTTGCACCATGAAGTTCCCCACTGTTCCGATGATGTTCAACCATCTCAAGACAACCCATCTGGACCGGATCAACAGCCCAAAGAGCTATCTGGAACAGTTCAACAAGAACCTCATGAACACGTACACCTCGTTCTACGGATCGTCAGCCTTCCTCGAAGACAAACACGAGCCGAACGCGGAGGTTAAAAATGAACGTCCCAGCAGTGAGAAAAGCATCCGGGATGAAAACGGCAACGAAGAGACGACCGCAGCTTCACCACCACCAATAGAACCCAAGGTCATCAAACAGGAAAAAAAGGATGAAAACGACAACTCCCAGGACGCTGCCGATCACCAGGAACAGCTCGCTCCAACCGACCTGAGTCAACCGCGCATGAAGCGACTCAAGCTGGAGCACGAGAACCATTCGACCTCGTCCTCCTCAAGTCGAGATATAACCCGCGAAGCGGAAAAAGACACCACCCCAGTGTCGAACCTATCAACCGCTCCGGGCGCATATCTCTGCAACCAGTGCAACGCCGCCCTGCCCGATTTCGAGTCCTTCCGAACCCATCTGAAAGCTCACCTCGAGCAGGGCTCAACGGCGTCCTCGTTCGTGTGTCAACAGTGCGGCGCCACCCTGGCCGACCAGCAGGAACACGAAAAGCACGTCACCGGGCACTACCTGGTGGCCGGAGCGGAGTACCAGTGCGAACCCACCTGCAGCAAGTCGTTCGCCAAGGCCGAAGAACTGCACAAACATCTGTACGACTCGCACACCCAGGTCCTGTACAAGTGCGTGCTGTGCGGCGAAACCTTCGACACCAAGGTCACCATCCAGGTCCACTTTGCCGTGGCCCACTCGAACGAGGTCAAGCTGTACCGGTGTTCTGCTTGCGCCGAGGTGTTCCGCGCCGAACGGGACTTTAGACATCACATCCGGACGCGTCACATCACTTCCGGTGCGGTTCAGTGCGTCTTCTGCCGCGTCGTGTGCACTTCCGAGCTGGAAATGCAGTTCCATCTGGCAGCCCACGCTCGCAAGTTCAAATGTCCCGCCTGCCCGGAATCGTTCCACGTCGAGTTCCTGCTGGACCGTCACATGCAAACCCACCACAGCCAGAAGGAAATCTCGAACGCGGCTGCCGCGGGAGCTTCAAGCACCACGGTCAACAACCAACCCACAAACAGCACCAACCTGGACTATCTCCAGCTGCACGGACAAATGGCCGCGGCAGCAGCGGCCGCCAACTGGCAAAATCTGTACGCCGCCAACAAGTTCTACAACCCGCTGCACGTGGACACGCTCAACCCGATCAAACATCCCAACTTCCTGCACGGCTTCTACGACAGCCTCAACAAGTCCCACGCCCAGCGCTACCTGGACCAGTCCAAGAAGGGCTTCGTCAgtcccaacaacaacaacaacaacaactcccaACAGTCCAAAGCGGCTCTTTTGAACCTGTACAACCAGCAGCGTTCGGCGGCCATGAACGGTCTCTACTCGCCGGATCACAATCCCGCATCCCAATCGGGCCAAACCGCCGCCAACGCTGCCCCCGCGACGACCAACAAATCTCCCCAGATCTACTCACCAACGGCTTTGCTGCACCGCTACGGACTCAACTCGTCCGGTTCCGGCAGTGGTTCGACAGCCAACAGCAACAACGGAAGCGCTTCCGCCGTTGCAGCACCGGAAAAGGCGACTTCCTCCAACACCAAGAACAACACCGTAAACTACTACAGCTGTGGAATCTGCGAGCGAACGGACTTTAGCACCGAGAACGAGGTCCAGACGCACCGTAAGATCGTGCACAACCTCAAGACTGGGGTGAGTCTGCGGTGTGCTTACTGCAGCGGGGACTTCCGGTCAAGAAACGAGCTGGAGAACCACATGAAAATCGCTCACAACACCGGCGGCAAGCACAAGTGTCTGATCTGCGACGAAATCTTCCCGTCGCCAGCGGTCCTGGCGGAACACAAGCTGACCCACTGCAAGGTGGGCGCCTCCGGCCGATGCTCGCACTGTCCAACGACTCTGCCCGATGTGCACAGCTTCAAGGCCCACCTCTCCCAGCACATTCAACCGGCGTCGGCGACTTCCTCGACGTCGTCAACGGGGAAGAACGAATCCAACGGAACGAGTTCCGGTCAAGAGCAGGAACGCTTTCCGATCCAGTGCATCTGCTGTCGCCAGACGCTCAACTCTGAGTTTGAGATTAGCTTGCATGCAAAATTCCACACCAAGTCCAGCGAAACCAACGAGAAAACGTGCGCCCTCTGTCTGGAACCGCTGGCCAACGGCCAGGACGCCAAGATCTGCGAAAGCTGCCTCAAGCGGCACAACTTTCCCTCGAAGCTGCTCTCAATCAACAACTTCATCAAGTCATCGTCGAGCTCCACCGCGGAAGACCCCACCAGCCACCATCACCAACACCATCCGCCTCCTACTCTAAGTCAATCCCCCGCCCAGTGCAACCTGTGCAAGAAGCACCTCTACGACGGACAAAAACTCCAGGAACACCTGATCGATCACACGTTCGCCGGCTGTGAAGATCGCGGCTTCGTGTGCTATCTCTGCTCATCGGTCTTCACCTCGTCCGGAGGACTGCAGACGCACATGGACCAACATGGTCCGCAGGCCAAGCCGTACGATTGTAACCACTGTGACGAAGCGTTCTTCTTCCGGGCCGAGCTGGAGCATCACCTGATTGACCACGAGCTGGGCAAGGTACATCTGCCGGCAGCGTTCGTCCAGGAGGAACACGCGCGGACGAGCCCGCCGGAGATTAAGCCGGAAATTGTCGAGGCGATCGTGGAGAAAACTACTCCAGCTGACGCCGATCCGGAAAGTGGTTCCGAACAGGAAGGGGGAATCGTCGCTGGGGAGGAACCGGAAGTGACGGAACGGGAAGAGGGGGAAGAGGATGACGAAGAGGTGGCGGATGATGATGACGAGTACATTGAGGTGGAGCACAACGTGGAGGAGAGTGCAAAGGAGGATCGTAAATCGATCGAGTGCTCGCAGTAA
Protein Sequence: MSRRKQAKPRAFKHDDDDDGLVENRGEAGGLLAVNDNSEKENDMPDNDTDADDDDDEEGEGEDGEEEADEDGAEMLEDGDEPENGGDPIKHELFDNDSINSNDYNDDDLTSESFCSELYSSHTSSSFSPSISDGMTTPNSITNDGDHHHQPGSANGGTADSEQAPAGQDKRGGHQHRRHHHHHHRSSADNNNKIIKNNNHTNSHSKNNDGTYRCQFCDKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQIALTGSPNLTYSPRSTSSLSSSASNPKRKFSPYEQNLMMINRSKLLKSGELTCIYCTRTDFANLEQLGAHVQTMHSNLLLNENNFHRMPTSPDALLSYPPISCEFCTMKFPTVPMMFNHLKTTHLDRINSPKSYLEQFNKNLMNTYTSFYGSSAFLEDKHEPNAEVKNERPSSEKSIRDENGNEETTAASPPPIEPKVIKQEKKDENDNSQDAADHQEQLAPTDLSQPRMKRLKLEHENHSTSSSSSRDITREAEKDTTPVSNLSTAPGAYLCNQCNAALPDFESFRTHLKAHLEQGSTASSFVCQQCGATLADQQEHEKHVTGHYLVAGAEYQCEPTCSKSFAKAEELHKHLYDSHTQVLYKCVLCGETFDTKVTIQVHFAVAHSNEVKLYRCSACAEVFRAERDFRHHIRTRHITSGAVQCVFCRVVCTSELEMQFHLAAHARKFKCPACPESFHVEFLLDRHMQTHHSQKEISNAAAAGASSTTVNNQPTNSTNLDYLQLHGQMAAAAAAANWQNLYAANKFYNPLHVDTLNPIKHPNFLHGFYDSLNKSHAQRYLDQSKKGFVSPNNNNNNNSQQSKAALLNLYNQQRSAAMNGLYSPDHNPASQSGQTAANAAPATTNKSPQIYSPTALLHRYGLNSSGSGSGSTANSNNGSASAVAAPEKATSSNTKNNTVNYYSCGICERTDFSTENEVQTHRKIVHNLKTGVSLRCAYCSGDFRSRNELENHMKIAHNTGGKHKCLICDEIFPSPAVLAEHKLTHCKVGASGRCSHCPTTLPDVHSFKAHLSQHIQPASATSSTSSTGKNESNGTSSGQEQERFPIQCICCRQTLNSEFEISLHAKFHTKSSETNEKTCALCLEPLANGQDAKICESCLKRHNFPSKLLSINNFIKSSSSSTAEDPTSHHHQHHPPPTLSQSPAQCNLCKKHLYDGQKLQEHLIDHTFAGCEDRGFVCYLCSSVFTSSGGLQTHMDQHGPQAKPYDCNHCDEAFFFRAELEHHLIDHELGKVHLPAAFVQEEHARTSPPEIKPEIVEAIVEKTTPADADPESGSEQEGGIVAGEEPEVTEREEGEEDDEEVADDDDEYIEVEHNVEESAKEDRKSIECSQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401984;
90% Identity: iTF_00401984;
80% Identity: -