Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NW:556928-583669[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.27 8.4 7.6 0.5 2 23 278 296 277 296 0.93

2 12 5.2e-07 1.6e-05 25.6 2.4 1 23 302 324 302 324 0.99

3 12 0.061 1.9 9.6 3.4 1 23 330 354 330 354 0.97

4 12 3.9e-06 0.00012 22.8 3.2 1 23 360 382 360 382 0.99

5 12 2.9e-05 0.0009 20.1 0.7 1 23 388 410 388 410 0.98

6 12 2.7e-05 0.00084 20.2 3.4 2 23 417 438 416 438 0.96

7 12 0.024 0.73 10.9 0.4 2 23 445 466 444 466 0.95

8 12 0.072 2.2 9.4 2.4 2 23 471 492 470 492 0.97

9 12 3.2e-05 0.00098 20.0 0.4 1 23 497 520 497 520 0.98

10 12 7e-05 0.0021 18.9 2.2 1 23 551 573 551 573 0.97

11 12 0.00021 0.0065 17.4 1.4 1 23 580 603 580 603 0.93

12 12 6.7e-05 0.002 19.0 0.5 3 23 611 631 609 631 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.27	8.4	7.6	0.5	2	23	278	296	277	296	0.93
2	12	5.2e-07	1.6e-05	25.6	2.4	1	23	302	324	302	324	0.99
3	12	0.061	1.9	9.6	3.4	1	23	330	354	330	354	0.97
4	12	3.9e-06	0.00012	22.8	3.2	1	23	360	382	360	382	0.99
5	12	2.9e-05	0.0009	20.1	0.7	1	23	388	410	388	410	0.98
6	12	2.7e-05	0.00084	20.2	3.4	2	23	417	438	416	438	0.96
7	12	0.024	0.73	10.9	0.4	2	23	445	466	444	466	0.95
8	12	0.072	2.2	9.4	2.4	2	23	471	492	470	492	0.97
9	12	3.2e-05	0.00098	20.0	0.4	1	23	497	520	497	520	0.98
10	12	7e-05	0.0021	18.9	2.2	1	23	551	573	551	573	0.97
11	12	0.00021	0.0065	17.4	1.4	1	23	580	603	580	603	0.93
12	12	6.7e-05	0.002	19.0	0.5	3	23	611	631	609	631	0.97

Sequence Information

Coding Sequence: ATGCATCACGGACGGAAGAAACGCACCACCGATAACGATGAGATAATTGCCCTGTGTCCGTCCAACTTGGGCTGCAACAACAACCTGAAGAGACCCAATCATCATCATCGTGTGACATCATCGTCGTCTATTAGGCAGGGCGCCAAACCCGTTGGAGAAATGCGGAAATCCGATCCGGTGGCCAGTCGCCGGACAAACCGGTTCAACGATGCGTTTGTGAAACATTTTCTAACGCAGCTGGGCATGGCCAACCCTTTCGAAAAGCAGGAAATCGGGTGCAAAATCTGCGACGGCACGAGCGGTGCCATGGAGTCGATCTTTTGCGCTCCCGACAACAGCCGCCTGCtggaaaaaatcttcaaatgtacAAATGTACGGGTGGTTCCCGTATGTGGGATAATTTCGCCGGTTTGCGAGTTTTGTCACGATCGCATTAATCAGTTTGATGAGAGTTTTAAGCCTCGGTGTAGCGAGTACGTTGTGGAGAAGGTTAAGAGGAGCGTAGAGCCGGATGATGATCCGTTTGGGTGTTTGGAGGATCCGATGGCGGTTGAGGAAGAGAATAAGGCGGTTAAAGTTGTGGATGTCCCCAAGGTTCGGGAGGTTAAAGTTCCGAAAATCTTGGAAGAAGCCAAGGTTGGAGTTGAAAATGTTACGGAACAGGTCGATGAGATCAGAAAGGAGCTGAATAACTTGTTGGAAGCGGTTGAGGAGGATCAAGTGGAGCATGATGATTGGGACGATCATCATGAAAATGATGAAGAATCTTCTGAAGCTGAGGAAAAGCCTAAATCTAAAAGAGAGGTTTTCGATAAACTAAGAAAGCTTTCCAAATGTGAAGTTTGCGGGAAGGAGGTGGCTTATTTGAAGGACCACATGCGGGTACACAAAAAGGAGAAAAAGTTCAAGTGTCCGCACTGCGATCGCGGGTTTAGTCAGAGCAGTAACTTGGTCTACCATGTTCGGAAGCACACCGGAGATAAGCCGTTTGTCTGCACTTATGATAAATGTGATAAAGCATTTATCTGCAAAGCGCATCTGCTTTCCCATGAGCGATCTCACATCGACGATAAGCCATTTCAGTGCGAAGTTTGCTCAAAACGCTTCAATcaggccTGTAATTTGACCAAACACCTTCGAGTTCACTCCGGAGCTAAGCCTTATACTTGCAGCATTTGCGGAAGAGACTTTATGAATCTCTCAAACATGAAGGCTCATGAAAAACGTCATAAAGGAGAGCGGAACTTATCCTGCCAATTGTGCCCTAAAACATTCTATGACAAGCATCATCTGGAACGTCACGCCCGCGTTCACTTCAAGCCGTCCAAAGTTTCCTGTAGCATTTGCTCCAAGGAATTCACATCGGAACGAGCCGCTAAAACCCACGAGCTGAAGCACACAGAACAGCtggtttgtaaaatttgctacaCCCACTTCGAAAGCGCCCGTTTGCTCAAGTTCCACATGAAGAGCCACGACCGGAAGCAGTTCCAGTGCCTCAACTGCCCGAAAAGCTTCATCCGGGAAGATGTGCTCACGAAGCACATTCAGCGCGTTCACGTGGACGGTCTGGCCAAGCCGAATCAAACGGTGATTCTGGTCGCTCCGGAGCGCGCCCAAGCTCAGCTGGACGCTGGCCTGGAGGAACCGTACTGCTGCCTGGTCTGCGACAAACTGTTTAGCACGTCGCAATCCCTTAAAGTTCACTTGCGAATCCACATTACCGGTGCGCGTCCATTTCCGTGCGTAAAGTGTCCCCGATCGTTCAACCAGAAGGAGCATCTGCGCGTGCACGACCGGACGATTCACACGGGGGAGCGGCCGTTTGGTTGTACTGTTTGCGGGGAGAGATTTGTGCGGGCACATTCGTTGAAGGAGCACATGCTGGGCCATGGAAGCGGATTGGTGCAGGAGGCGGAGCTGGAGGTCAGTGAGGAGGTGGAGGTTATAACCGGGGATGTGTGCCCTGAGGAGATCGGAGGCGATGCGCAGCTGGTGGAGCTGGCGTCGAGTGTGGTTCCGGAGACCGGACAGGTCGTTGTTAAGTTTGAGGTGAAATGTGCGAAATGA
Protein Sequence: MHHGRKKRTTDNDEIIALCPSNLGCNNNLKRPNHHHRVTSSSSIRQGAKPVGEMRKSDPVASRRTNRFNDAFVKHFLTQLGMANPFEKQEIGCKICDGTSGAMESIFCAPDNSRLLEKIFKCTNVRVVPVCGIISPVCEFCHDRINQFDESFKPRCSEYVVEKVKRSVEPDDDPFGCLEDPMAVEEENKAVKVVDVPKVREVKVPKILEEAKVGVENVTEQVDEIRKELNNLLEAVEEDQVEHDDWDDHHENDEESSEAEEKPKSKREVFDKLRKLSKCEVCGKEVAYLKDHMRVHKKEKKFKCPHCDRGFSQSSNLVYHVRKHTGDKPFVCTYDKCDKAFICKAHLLSHERSHIDDKPFQCEVCSKRFNQACNLTKHLRVHSGAKPYTCSICGRDFMNLSNMKAHEKRHKGERNLSCQLCPKTFYDKHHLERHARVHFKPSKVSCSICSKEFTSERAAKTHELKHTEQLVCKICYTHFESARLLKFHMKSHDRKQFQCLNCPKSFIREDVLTKHIQRVHVDGLAKPNQTVILVAPERAQAQLDAGLEEPYCCLVCDKLFSTSQSLKVHLRIHITGARPFPCVKCPRSFNQKEHLRVHDRTIHTGERPFGCTVCGERFVRAHSLKEHMLGHGSGLVQEAELEVSEEVEVITGDVCPEEIGGDAQLVELASSVVPETGQVVVKFEVKCAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401954; iTF_00400852;
90% Identity: iTF_00400852;
80% Identity: -