Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:3735153-3737875[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.28 8.4 7.6 0.7 2 23 203 221 202 221 0.93

2 12 4.5e-07 1.4e-05 25.8 2.4 1 23 227 249 227 249 0.99

3 12 0.053 1.6 9.8 3.4 1 23 255 279 255 279 0.97

4 12 3.4e-06 0.0001 23.0 3.2 1 23 285 307 285 307 0.99

5 12 2.6e-05 0.00078 20.3 0.7 1 23 313 335 313 335 0.98

6 12 2.4e-05 0.00073 20.4 3.4 2 23 342 363 341 363 0.96

7 12 0.14 4.4 8.5 0.5 2 23 370 391 369 391 0.95

8 12 0.0097 0.3 12.1 1.1 2 23 396 417 395 417 0.97

9 12 2.8e-05 0.00085 20.2 0.4 1 23 422 445 422 445 0.98

10 12 6.1e-05 0.0019 19.1 2.2 1 23 476 498 476 498 0.97

11 12 0.00018 0.0056 17.6 1.4 1 23 505 528 505 528 0.93

12 12 1.1e-05 0.00035 21.4 0.4 3 23 536 556 534 556 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.28	8.4	7.6	0.7	2	23	203	221	202	221	0.93
2	12	4.5e-07	1.4e-05	25.8	2.4	1	23	227	249	227	249	0.99
3	12	0.053	1.6	9.8	3.4	1	23	255	279	255	279	0.97
4	12	3.4e-06	0.0001	23.0	3.2	1	23	285	307	285	307	0.99
5	12	2.6e-05	0.00078	20.3	0.7	1	23	313	335	313	335	0.98
6	12	2.4e-05	0.00073	20.4	3.4	2	23	342	363	341	363	0.96
7	12	0.14	4.4	8.5	0.5	2	23	370	391	369	391	0.95
8	12	0.0097	0.3	12.1	1.1	2	23	396	417	395	417	0.97
9	12	2.8e-05	0.00085	20.2	0.4	1	23	422	445	422	445	0.98
10	12	6.1e-05	0.0019	19.1	2.2	1	23	476	498	476	498	0.97
11	12	0.00018	0.0056	17.6	1.4	1	23	505	528	505	528	0.93
12	12	1.1e-05	0.00035	21.4	0.4	3	23	536	556	534	556	0.98

Sequence Information

Coding Sequence: ATGAGTTTGATGAAATCCACTGTCTGCCCCTTCGAAAAGCAGGAAATTGGGTGCAAAATCTGCGATGGCACGAGCGGTGCCATGGAGTCGATCTTTTGCGCTACCGACAACAGCCGCCTGCTGGACAAAATCTTTAAATGTACAAATGTACGGGTGGTTCCCGTATGTGGGATAATTTCACCGGTTTGCGAGTTTTGCCACGATCGCATTAATCAGTTTGATGAGAGTTTTAAGCCCCGGTGTAGCGAGTACGTTGTGGAGAAGGTTAAGAGGAGCGTAGAGCCGGACGATGATCCGTTTGGGTGTTTGGAGGATCCGATGGCGGTTGAGGTAGAGCATAAGGTGGTTAAGGTTGTGGAGGTTCCCAAGGTTCGGGAGGTTAAAGTTCCGACGATCATGGAAGAGGCCAAGGTTGGAGTTGACAATGTTTTGGAACAGGTCGATGAGATCAAGAAAGAGCTGAATAACTTGTTGGAAGCGGCTGAGGAGGATCAAGTGGAGGATGATGATTGGGACGACAATAAGGAGGATGGTGAGGGAAATTCTGAAGCTGAGGAAAGGCCTAAATCTAAAAGGGAGGTTTCCGATAAACCAAAAAAGCTTTCCAAATGTGAGGTTTGCGGGAAGGAGGTGGCTTATTTGAAGGACCACATGCGGATTCACAAGAAGGAGAAGAAGTTCAAGTGTCCGCACTGCGATCGCGGGTTTAGTCAGAGCAGTAACTTGGTCTATCACGTTCGGAAGCACACCGGAGATAAGCCATTTGTCTGCACTTATGATAAATGTGATAAAGCATTCATCTGCAAAGCGCACCTGCTTTCCCATGAGcGATCTCACATCGATGATAAGCCATTCCAGTGCGAAGTTTGCTCAAAACGCTTCAATCAGgcgtGTAATTTGACCAAACATCTTCGCGTGCACTCTGGAGCGAAACCTTACACTTGTAGCATTTGCGGAAGAGACTTTATGAATCTCTCAAACATGAAGGCTCATGAGAAACGCCATAAAGGAGAGCGGAACTTATCCTGCCAGTTATGCCCTAAAACATTCTATGACAAGCATCATCTGGAACGTCACGCCCGCGTTCATTCCAAGCCGTCCAAAGTTTCATGTGGCTTCTGCTCCAAAGAATTCACATCGGAACGAGCCGCCAAAACCCACGAGCTCAAGCACGCGGAACAGCTGGTTTGTAAGATTTGCTTCACCACCTTCGAAAGCGCCCGTTTGCTCAAGTTCCACATGAAGAGCCACGACCGGAAGCAGTTCCAGTGCCTCAACTGCCCGAAAAGTTTCATCCGGGAAGATGTGCTCACGAAGCACATTCAGCGCGTTCACGTGGACGGTCTGGCCAAGCCGAATCAAACGGTGATTCTGGTCGCTCCGGAGCGCGCCCAAGCTCAGCTGGACGCTGGCCTGGAGGAACCGTACTGCTGTCTGGTCTGTGACAAGCTGTTTAGCACGTCACAATCGCTTAAAGTGCACTTGCGAATCCACATTACCGGAGCGCGTCCGTTTCCGTGCGTAAAGTGTCCACGATCGTTCAACCAGAAGGAGCACCTGCGCGTGCACGACCGGACGATTCACACGGGGGAGCGGCCGTTTGGTTGTACTGTTTGTGGGGAGACATTTGTGCGGGCACATTCGTTGAAAGAGCACATGCTGGTTCATGAACGTGGATTGTCGCTGGAGGTCAGTGAGGAGGTGGAAGTTATAACTGGGGACGTGGACGCTGAGGAGATTGGAGGGGATGCGCAGTTGGTGGAGCTGGCGTCGAGTGTGGTTCCGGAGACCGGACAGGTCGTTGTTAAGTTTGAGGTGAAATGTGCGAAATGA
Protein Sequence: MSLMKSTVCPFEKQEIGCKICDGTSGAMESIFCATDNSRLLDKIFKCTNVRVVPVCGIISPVCEFCHDRINQFDESFKPRCSEYVVEKVKRSVEPDDDPFGCLEDPMAVEVEHKVVKVVEVPKVREVKVPTIMEEAKVGVDNVLEQVDEIKKELNNLLEAAEEDQVEDDDWDDNKEDGEGNSEAEERPKSKREVSDKPKKLSKCEVCGKEVAYLKDHMRIHKKEKKFKCPHCDRGFSQSSNLVYHVRKHTGDKPFVCTYDKCDKAFICKAHLLSHERSHIDDKPFQCEVCSKRFNQACNLTKHLRVHSGAKPYTCSICGRDFMNLSNMKAHEKRHKGERNLSCQLCPKTFYDKHHLERHARVHSKPSKVSCGFCSKEFTSERAAKTHELKHAEQLVCKICFTTFESARLLKFHMKSHDRKQFQCLNCPKSFIREDVLTKHIQRVHVDGLAKPNQTVILVAPERAQAQLDAGLEEPYCCLVCDKLFSTSQSLKVHLRIHITGARPFPCVKCPRSFNQKEHLRVHDRTIHTGERPFGCTVCGETFVRAHSLKEHMLVHERGLSLEVSEEVEVITGDVDAEEIGGDAQLVELASSVVPETGQVVVKFEVKCAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400854;
90% Identity: iTF_00401954; iTF_00400854;
80% Identity: -