Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:138352058-138355312[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.1 95 4.3 0.1 2 23 233 255 232 255 0.95

2 16 0.041 1.3 10.2 0.3 1 23 290 313 290 313 0.98

3 16 0.001 0.031 15.2 5.0 1 23 327 349 327 349 0.97

4 16 1 32 5.8 0.4 2 23 365 387 364 387 0.88

5 16 0.024 0.72 10.9 0.6 2 23 423 444 422 444 0.97

6 16 7e-05 0.0022 18.9 0.6 1 23 476 498 476 498 0.97

7 16 0.00077 0.024 15.6 0.3 1 23 504 527 504 527 0.95

8 16 0.00025 0.0075 17.2 0.6 1 22 533 554 533 557 0.90

9 16 0.0031 0.095 13.7 0.1 1 22 563 584 563 584 0.96

10 16 0.25 7.5 7.7 1.0 2 23 625 646 624 646 0.88

11 16 0.053 1.6 9.8 7.4 2 23 653 674 652 674 0.97

12 16 5.1e-07 1.6e-05 25.6 0.8 1 23 681 703 681 703 0.98

13 16 0.00023 0.0069 17.3 1.0 1 23 709 731 709 731 0.98

14 16 2.7e-05 0.00082 20.2 0.4 1 23 762 784 762 784 0.99

15 16 1.6e-05 0.0005 20.9 0.5 1 23 790 812 790 812 0.99

16 16 0.005 0.15 13.1 0.2 1 21 818 838 818 839 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.1	95	4.3	0.1	2	23	233	255	232	255	0.95
2	16	0.041	1.3	10.2	0.3	1	23	290	313	290	313	0.98
3	16	0.001	0.031	15.2	5.0	1	23	327	349	327	349	0.97
4	16	1	32	5.8	0.4	2	23	365	387	364	387	0.88
5	16	0.024	0.72	10.9	0.6	2	23	423	444	422	444	0.97
6	16	7e-05	0.0022	18.9	0.6	1	23	476	498	476	498	0.97
7	16	0.00077	0.024	15.6	0.3	1	23	504	527	504	527	0.95
8	16	0.00025	0.0075	17.2	0.6	1	22	533	554	533	557	0.90
9	16	0.0031	0.095	13.7	0.1	1	22	563	584	563	584	0.96
10	16	0.25	7.5	7.7	1.0	2	23	625	646	624	646	0.88
11	16	0.053	1.6	9.8	7.4	2	23	653	674	652	674	0.97
12	16	5.1e-07	1.6e-05	25.6	0.8	1	23	681	703	681	703	0.98
13	16	0.00023	0.0069	17.3	1.0	1	23	709	731	709	731	0.98
14	16	2.7e-05	0.00082	20.2	0.4	1	23	762	784	762	784	0.99
15	16	1.6e-05	0.0005	20.9	0.5	1	23	790	812	790	812	0.99
16	16	0.005	0.15	13.1	0.2	1	21	818	838	818	839	0.94

Sequence Information

Coding Sequence: ATGCTTCTGCGGCACGTCATCCCGACCAACAACGATGTGGAGGAAATTTACATCGTCAAGCAGGAAGATGAGCAGACCGATCCGGCTGGCAACCCGCTGGCGGGCGGACCAGGGCCTAGTCGGTCCGGGTTGCATCCGACGGCGCTGCTCGAGAACGAGGACGTTGAAATCAAGGACGAACCGCTGAGCGTGCAGGGTAGCGAGGAGGAAGATGAAAAGTACGATCCCCCGGTTCCGCTGCTGCATGCCCTTCCGGTCGAGGTGCGGCTGGTTGAAGATTTGCCGAAAAAGTTGGAGGCTGCGATCAAAAAGGAGAAGGAAGtggaggagcagcagcagcaaacgaGGAAGTCTCCGGTGGAACCGGTAAAAGCGGTCAAGCATAGTGTGAAGCAGGAGAGGGACTCCAGCTCGGACGGTGACTGGGGACAGGATGACTTTGAGCCACTGGCTAAGGAGGTGGTGGTCAAGAGGAAGCGTGGCCGGCCACCGAAGAAAAAGGTTGAGGTAAAGAAGGAAAAGTCAGCTGGTTCTGATAGCGATATGGACGCGGACGATGTGGATGATGACGATTATAGACCTCCAGCGGGTAGTCCGGTCAAGAAGGAGCGCAAACGAGGTCGCAAGAAAAAGATCAAGACGGAACCGGATGGGTTCGATAGCGATGCTTCCAACGTGGAGGAAACGGAAATAGTCAAATGCTTCATTTGCGTGATTGACCTGAAGGAGGCCGATCTGCTGGACAAACATTTGCGCCAAAAGCACAAGCACATGCTTCCGTTTAGCTGCGTTACGTGCGTGGGACGTAGGGTAACACGGTTGAAGGATTTGAACTTGCACTTTCAGCAGCATGACGAGACTAGGAAGTATAAGTGTCTCTATTGTGCGGCGCGGTTCCCATCGCCACAGGGACAGAGCAGCCACATGCGTCGGATGCACAGCGAGAAGTACAACACCGATATGGATCGCTATCGGCGGTTCATGTGCCGCTTTTGCGATAAAAAGTTCACCAAGAAACACGACTTGGAAATTCACGAGAAGCGTCACATCGCGGAGGAGTCGAACGATCCGGCAGTTATGCGACGAGCTCTGAAGTGTTacatttgcaacaaatttgtgGGGAAGAATCGAGATGATCTGAACACACACGTCGCTACGCACGAAGACTGGCTTCCGTATCACTGCGAAAAGTGTGACAACAAAAAGATTTGCACCGTTCGAATACTTTGCGAGCACCTGCGGCAGCACCAGGAGGGACTGGCGGTTAAATGCGTTTACTGCGATGAACGGTTCGTCAGTTTGGGCGAATGTCAGGCTCACGAGCGGACTCACGCGGCGGAGAAGGAAGCGCACGAAATTGAGGACGCGAAAATGATCGCGGAAATGACCGGAAACAGCGTCGTTGTGGTGGATGGCGTCAAACGGTTCCAGTGCGGCAAGTGTGACCGGTCGTACGCGTTGTCCAGCAGTCTGCGGAAGCATCAGGGTGTCCATGCCAAGGGAAATGCGTTCGTTTGTTCAAAATGTGGCCGAGCGTTCATGAAGGCTTCGTCGTTGGCATTGCACGAGAGTCGTAACCACCTGGAAGGAGGCAGTTTCACGTGCGAAGGTTGTGGTAAAGTTTTCCCGACAATTGGACACCTGCTGGATCACCGAACCCGAACTCAGCACTTTGCCGGAAAGCCGTTCATTTGCGAGGGTTGTACGACCACGTTCGTGCTGCAGGAAGAGCTGACGGAGCACCAGAAGACGTGCACCGAAACGGAAGCGAATCGAGCGTGCTTCTGCGGTCTCTGCGCCAACAATTTCCCCTCTCTGGCGATTGCGATGGAACACGTCAAAAGCGAACACGAGCCGGAAATTCCGGAAACCAAGTGCAGATATTGCGATCTGACCTTCAGGGACTCGGAGCGAATTGTGGAGCACGAATTCAAGCACACTCTGCCGGGAATTATGACCTGCAAGATGTGCAACCGGATCTTTAAGCACTTGAAGAATTTGCAGTGCCACATGAAGAACCATGGCAAGGTGGCGATTCCGTTCATGTGCGATATCTGCGGCAAAACGTTCACCCAGAAGGGCACGCTCACTATTCATACGCGTCTTCATACGGGCGAGCGTCCGTATACCTGCGTACTGTGCCAGAAGGGATTCGTCGACAAGAACGAGATGAGAAGACACTACAATATGCATTTCAATCCACAGAGCAAGCTGTACATTCCGAACGCGCAGCAGATCGCCGCCCCGGTGGACGTCGGAGCGCAGGGCAAAAAGTACAAACAGTACACGTGCAAGATCTGCGGCCGCCAGCTGACGACGTCGACGGCGCTGGCCAAGCACATCACAACGCATACGGGTGAAAAGAAATATCAATGCGAATTCTGTGACAAACGCTTTGCCCAAGGAGGGCAATTGACGGTACATCGACGAATCCACACCGGCGAGCGTCCGTTTGCGTGCGAGAAATGTGGCCAGCGGTTCGTAGGAGGCAGCAATTACAAGCGTCACGTCAAGCAGGGCATGTGTAAGGCGCTAACTGCTGGAGCGATCCCTTCCGGTGAAGGCGGAACAGCGAACATGCACccacagcaacagcagcagcagctggagcACCCGTATCTCGGCGGTGCCGAGGTGATTGGAAGTTCGGAACTACGGATCTACCCCGACGAAAAGGAAATGCACTAG
Protein Sequence: MLLRHVIPTNNDVEEIYIVKQEDEQTDPAGNPLAGGPGPSRSGLHPTALLENEDVEIKDEPLSVQGSEEEDEKYDPPVPLLHALPVEVRLVEDLPKKLEAAIKKEKEVEEQQQQTRKSPVEPVKAVKHSVKQERDSSSDGDWGQDDFEPLAKEVVVKRKRGRPPKKKVEVKKEKSAGSDSDMDADDVDDDDYRPPAGSPVKKERKRGRKKKIKTEPDGFDSDASNVEETEIVKCFICVIDLKEADLLDKHLRQKHKHMLPFSCVTCVGRRVTRLKDLNLHFQQHDETRKYKCLYCAARFPSPQGQSSHMRRMHSEKYNTDMDRYRRFMCRFCDKKFTKKHDLEIHEKRHIAEESNDPAVMRRALKCYICNKFVGKNRDDLNTHVATHEDWLPYHCEKCDNKKICTVRILCEHLRQHQEGLAVKCVYCDERFVSLGECQAHERTHAAEKEAHEIEDAKMIAEMTGNSVVVVDGVKRFQCGKCDRSYALSSSLRKHQGVHAKGNAFVCSKCGRAFMKASSLALHESRNHLEGGSFTCEGCGKVFPTIGHLLDHRTRTQHFAGKPFICEGCTTTFVLQEELTEHQKTCTETEANRACFCGLCANNFPSLAIAMEHVKSEHEPEIPETKCRYCDLTFRDSERIVEHEFKHTLPGIMTCKMCNRIFKHLKNLQCHMKNHGKVAIPFMCDICGKTFTQKGTLTIHTRLHTGERPYTCVLCQKGFVDKNEMRRHYNMHFNPQSKLYIPNAQQIAAPVDVGAQGKKYKQYTCKICGRQLTTSTALAKHITTHTGEKKYQCEFCDKRFAQGGQLTVHRRIHTGERPFACEKCGQRFVGGSNYKRHVKQGMCKALTAGAIPSGEGGTANMHPQQQQQQLEHPYLGGAEVIGSSELRIYPDEKEMH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401946;
90% Identity: iTF_00401946;
80% Identity: -