Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:21273881-21275993[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00032 0.0099 16.8 2.5 3 23 65 85 63 85 0.96

2 12 1.1e-06 3.4e-05 24.5 1.5 1 23 93 116 93 116 0.95

3 12 7.5e-05 0.0023 18.8 2.4 1 23 149 171 149 171 0.99

4 12 2.7e-06 8.4e-05 23.3 0.2 1 23 179 202 179 202 0.98

5 12 0.8 24 6.1 6.0 1 23 221 243 221 243 0.97

6 12 0.00015 0.0045 17.9 0.8 1 23 252 274 252 274 0.94

7 12 1.3e-05 0.00039 21.2 1.3 2 23 288 309 287 309 0.98

8 12 0.0063 0.19 12.7 0.3 1 23 317 339 317 339 0.94

9 12 0.00016 0.0049 17.7 0.2 1 23 362 384 362 384 0.98

10 12 2.1e-05 0.00065 20.5 2.0 1 23 392 414 392 414 0.99

11 12 3.1e-05 0.00094 20.0 4.1 1 23 430 452 430 452 0.97

12 12 0.2 6.2 8.0 0.2 1 23 460 482 460 482 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00032	0.0099	16.8	2.5	3	23	65	85	63	85	0.96
2	12	1.1e-06	3.4e-05	24.5	1.5	1	23	93	116	93	116	0.95
3	12	7.5e-05	0.0023	18.8	2.4	1	23	149	171	149	171	0.99
4	12	2.7e-06	8.4e-05	23.3	0.2	1	23	179	202	179	202	0.98
5	12	0.8	24	6.1	6.0	1	23	221	243	221	243	0.97
6	12	0.00015	0.0045	17.9	0.8	1	23	252	274	252	274	0.94
7	12	1.3e-05	0.00039	21.2	1.3	2	23	288	309	287	309	0.98
8	12	0.0063	0.19	12.7	0.3	1	23	317	339	317	339	0.94
9	12	0.00016	0.0049	17.7	0.2	1	23	362	384	362	384	0.98
10	12	2.1e-05	0.00065	20.5	2.0	1	23	392	414	392	414	0.99
11	12	3.1e-05	0.00094	20.0	4.1	1	23	430	452	430	452	0.97
12	12	0.2	6.2	8.0	0.2	1	23	460	482	460	482	0.96

Sequence Information

Coding Sequence: ATGGCCGAAATTACGGTGAAAACGGAGCCCGGTTACGAAATGCACTCCACCCTGGAGGATCAGCAAACGCAGCAGGAGGAATCTAAGGCCACGACTTCTTTCTGTTACGAAACTGTGACGAAGGAAGAAGTAATCCTGGAAGACGAATTTGTTTCGCCAGAAGAGGAGAGCGCCACCAAACAAGATATGTTTTGTGAAGAATGCAACAAATCGTTCACAAATCGAGCGCTTTTCAGAACTCACAAGTATAAACATAAGGTTGTCAAAGAGGGAAAGTATACCTGCCAAATCTGCGATAAGTGCTTTAGAGACAAATATGCTCTGACCATTCACCTGCAGGGCATTCATCTGGTGTCCAAGCTcactaaaaacaaaaagaacGAAGAATTGAACGAACCGGATGTTAAACAgtttccaaaaaccatcacGAACGAAAATGGACAATTCAAATGCACCGAGTGTGACGAGAGATTTGAGTTCCAGTACCTGCAGCAGCGACACATTCGAAGGCATTCGGCATTGAAGCAAGGGTTGTACAAGTGCGAAGAGTGCAATAAGGCCTTTGCTACGCCCAGTGAAATCAAAAGTCACCTCAAACGAGCTCACGAGAAACATGCACAGAAGAGTTCGGAAGTTTCCGTGCAGGAAGAGGATGGAGTGTTTATCTGCAGTAAATGTAACAGGAAGTTTGAGGAGCGACACTTGTGCCAGCAACATATTTTGAGACATTTGGCACTGATGAAGGAACGGGTTTTCACTTGCTCCAAGTGTCCTAAGaaattcaTATCAgaaaaatatctcgaaaaacaTGAAGCATGGCACGAAGTAAAAGCAGCTCGTGTCGAACAATGTGAAATGGTGAAATGCGACGAGTGTAACAGGGAATTCCGAAATAAGCTCCTGTTGTCCCGACATATTCGCAGGCACAAGCTCATAAAAGAAGGCAAATTCCTTTGCGAGATTTGTGACGCGCGATACACAGCCAAGCGGCAGTTGATGAAACACGCAGAGAAGCATAAGAAGAATCCGTACCTGCCGTCATTCGAGCCTCCCGTTGTAATTGAACGGAACAACCACAGCGCGTTCAAGTGTCCGGACTGTGGCATGGTATTCACCGTTCGACGTGCGTATGACAATCACGCGCAGAGGCATGTAAATTTACGAAATGGCACGTACAAGTGCGACATTTGTGAGAAGGTGTGCGGATCAGAAAACAATCTGTACAATCATATGCGGCGCCACCGAATTGGCGAAATAAAGGAAATTTCTGAGCCGAGAGATCTTCCGTTTGATTGTCCCAAGTGTGATAAGAAGTTTGGCAAGAAGCATCTTTTGAAAAGACACACCAAAGTGCACGAGGCGATAGAAAAGGGTCTCTACAAGTGCAAGACTTGTTTGAAGTACCTAGGATCATCTGCCTCGCTTGCGATACACGAACAGGGACACACTGGCAAGACCGCAAAGGATTAA
Protein Sequence: MAEITVKTEPGYEMHSTLEDQQTQQEESKATTSFCYETVTKEEVILEDEFVSPEEESATKQDMFCEECNKSFTNRALFRTHKYKHKVVKEGKYTCQICDKCFRDKYALTIHLQGIHLVSKLTKNKKNEELNEPDVKQFPKTITNENGQFKCTECDERFEFQYLQQRHIRRHSALKQGLYKCEECNKAFATPSEIKSHLKRAHEKHAQKSSEVSVQEEDGVFICSKCNRKFEERHLCQQHILRHLALMKERVFTCSKCPKKFISEKYLEKHEAWHEVKAARVEQCEMVKCDECNREFRNKLLLSRHIRRHKLIKEGKFLCEICDARYTAKRQLMKHAEKHKKNPYLPSFEPPVVIERNNHSAFKCPDCGMVFTVRRAYDNHAQRHVNLRNGTYKCDICEKVCGSENNLYNHMRRHRIGEIKEISEPRDLPFDCPKCDKKFGKKHLLKRHTKVHEAIEKGLYKCKTCLKYLGSSASLAIHEQGHTGKTAKD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401933;
90% Identity: iTF_00401933;
80% Identity: -