Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:184978482-184983124[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.016 0.49 11.5 5.2 1 23 173 195 173 195 0.97

2 15 0.0004 0.012 16.5 0.9 1 23 223 246 223 246 0.90

3 15 6.9e-06 0.00021 22.1 4.3 1 23 252 274 252 274 0.98

4 15 2.8e-05 0.00085 20.2 2.5 1 23 280 303 280 303 0.95

5 15 0.0038 0.12 13.4 0.4 1 19 309 327 309 330 0.94

6 15 0.0007 0.022 15.7 1.5 1 21 336 356 336 358 0.95

7 15 4.9e-07 1.5e-05 25.7 1.0 1 23 367 389 367 389 0.99

8 15 6.7e-06 0.00021 22.1 0.5 1 23 395 417 395 417 0.98

9 15 0.00051 0.016 16.2 1.5 1 21 424 444 424 445 0.94

10 15 0.00031 0.0095 16.9 1.0 1 23 548 570 548 570 0.98

11 15 8.2e-07 2.5e-05 25.0 1.9 1 23 588 610 588 610 0.98

12 15 0.0095 0.29 12.2 0.4 1 23 617 639 617 639 0.97

13 15 0.00015 0.0046 17.8 3.2 1 23 647 669 647 669 0.98

14 15 2.8e-06 8.6e-05 23.3 0.3 1 23 675 697 675 697 0.98

15 15 0.4 12 7.1 0.0 3 23 706 726 704 726 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.016	0.49	11.5	5.2	1	23	173	195	173	195	0.97
2	15	0.0004	0.012	16.5	0.9	1	23	223	246	223	246	0.90
3	15	6.9e-06	0.00021	22.1	4.3	1	23	252	274	252	274	0.98
4	15	2.8e-05	0.00085	20.2	2.5	1	23	280	303	280	303	0.95
5	15	0.0038	0.12	13.4	0.4	1	19	309	327	309	330	0.94
6	15	0.0007	0.022	15.7	1.5	1	21	336	356	336	358	0.95
7	15	4.9e-07	1.5e-05	25.7	1.0	1	23	367	389	367	389	0.99
8	15	6.7e-06	0.00021	22.1	0.5	1	23	395	417	395	417	0.98
9	15	0.00051	0.016	16.2	1.5	1	21	424	444	424	445	0.94
10	15	0.00031	0.0095	16.9	1.0	1	23	548	570	548	570	0.98
11	15	8.2e-07	2.5e-05	25.0	1.9	1	23	588	610	588	610	0.98
12	15	0.0095	0.29	12.2	0.4	1	23	617	639	617	639	0.97
13	15	0.00015	0.0046	17.8	3.2	1	23	647	669	647	669	0.98
14	15	2.8e-06	8.6e-05	23.3	0.3	1	23	675	697	675	697	0.98
15	15	0.4	12	7.1	0.0	3	23	706	726	704	726	0.97

Sequence Information

Coding Sequence: ATGGCAGAAGATTTATCGATCAATAAAAATAAGATCTGTGCTTCGCGGTACCACAACAACGACATCTGTCGTCTGTGCTTGAAGAATGAGGCCCATATGGAGCCGCTTTTTTACGAGAATCTATTTCCGAACATTCTGCTCACCAAGAAGATTTACGACTGCACGTCGATACAGATAATTTACGAGCGCAACCTGCCAATGTTCGTGTGCAAACTGTGCGCCAACAAGCTGGACGAGTACATGAGATTCCGAGAACGGTGCGTAGCCAACGATGAGTTTCTGCGGAACGCGCTGGCATTCTTCGACGCTGGCCAGAACAGCATCAAGCTGGAACAGCAACACCACGAAGAAATTAAGCAGGAACCCTCCAGCCATGGACATTCGATTCAGCAGACGCAGCAATACTCAGTTGCAACGGCTCCGATTGACTTTCGCCAGATTAAACGTTCGCCGGAACgggtcgacgacgacgaggaagaGCCCCTTGAAGACGAGCCCGAGGAAGACGACAAAACGTACTCGTGCACGGTCTGCTCGAAATCGTTCAAGATTCGGCAGCATTTGCTGATTCACAGCCATACCCACGTGGAGCTTCTACAACCACAGCAGCAACAGCCGCAGCAATCGCGTCAGGAACCAGTGACGACACCGGAGGGCAAGCCCACATACAGCTGTGGCAAGTGCACCAAGGTGTTCATCAACCGGGGCAATCTGCTGAACCACGCCGCAGAGTGCCACGGTCATGTGAAGAACTTTTGCTGTCAGATTTGCAACAAATCTTTCAAATACAATGTACAACTTCGAATTCACCTTCGCACACACTCCGGAGAGCGGCCTCACGCGTGCGAGATATGCCATCGTGGGTTTTCCCAACTTTCAAACCTTAGGTCGCACCGTAAGGTTGTCCACTCCAAGGTCAAGCCGTACAAGTGTCAGCTGTGCTTGAAAAGCTTCACCATGCTGGACAGCCTGACCGCGCACAGCCTAAAGTGCGTCAAGGACAAGTACCGGTGCCAACTGTGCTCGAAGTCGTTCGCCAAAGAGGGCAACCTGATCGCGCATCTGCAGTGCCATAGCGAGGGGGTCATCGAGAAGAACTTCAAGTGTGAAATGTGCCCCAAAAGCTTTCGCAACAAGGAAGACTGGAAGCGGCACGTACGCGTCCACACGGGTGAAAAACCCTACATCTGCGACCTGTGCAACAAAGGGTTCGCGCAGAAAGCCAACCTGCTGTCCCACCGCAAGACTCACCTCAAGCCGGAAGTCATCTTCAAGTGCGAACGCTGCGGCAAGGTGTGTCGCACGCAGAAACTGCTCGAACTGCACGTGCAAAAGTGTGGCCTGCTCGAACTGCCCGGTACTCCGGTCCCCTCCGTGCCACCGACGCCGTCTTCGATGGGCTCGCCACCACCGCTGGGAGAagcggcagcagcagcgccGGCCACACCCACGCTCGAGACGCTGTCCGACCTGCTGCGGTACGAGTTTGCCATGCGGGCACCCATCGAGCTGCAGGATCTGCTGATGGCCACGATGGAGAAGAAGCGGGCggcggatgctgctgctgcggcgatTGTCTCGACGCCAGCGGTTGTTGCAGCACCGAACCCGGCACCGCCCAACGCCGCTGCTCGTCACACGTATCGGTGCGAAATTTGCTTCAAAGCGTACTCGCAGTACCCGAGCCTGGTTAAGCACCGGAAGCTGCATCTGAAGACGCCCCGGGCGAGGACCAAGTCCACCGAGGCGGACGATCGGCCGTACTATTGTGATATCTGCGGGAAGAACTTCAAGTTCAACCGGAATCTGAAGGTCCACATGAAGCTGCACACCAAAGCGAACGGGTTCTACAAGTGCGACAAGTGCAGCGGGACGTTCGAAACGGGCGAACTGCTGAAGACGCACCTGCTGGAGCACCCGATCGACGTCGAGAAGATCTTCAACTGCGAGTTCTGCTCGAACACGTTCAAATCGAACGAGGACCTGAAGCGGCACCGAAGGTCCCACACTGGGGAACGTCCGTTCAAGTGTGAGGCGTGTCCGAAGGCTTTCACGCAGCTGTCGAATCTGCGCGCCCACACCAAGATTCACGAGAAGAAGCGGCCGGCGTACGGGTGCAACATTTGCCTGCTGGAGCTGGACTCACTGGAGGCGCTGAACGTGCACCTGAAGACGCACCAGTTTCAGCTGTTTGAACTGTGCAAGGATATGAAGTAG
Protein Sequence: MAEDLSINKNKICASRYHNNDICRLCLKNEAHMEPLFYENLFPNILLTKKIYDCTSIQIIYERNLPMFVCKLCANKLDEYMRFRERCVANDEFLRNALAFFDAGQNSIKLEQQHHEEIKQEPSSHGHSIQQTQQYSVATAPIDFRQIKRSPERVDDDEEEPLEDEPEEDDKTYSCTVCSKSFKIRQHLLIHSHTHVELLQPQQQQPQQSRQEPVTTPEGKPTYSCGKCTKVFINRGNLLNHAAECHGHVKNFCCQICNKSFKYNVQLRIHLRTHSGERPHACEICHRGFSQLSNLRSHRKVVHSKVKPYKCQLCLKSFTMLDSLTAHSLKCVKDKYRCQLCSKSFAKEGNLIAHLQCHSEGVIEKNFKCEMCPKSFRNKEDWKRHVRVHTGEKPYICDLCNKGFAQKANLLSHRKTHLKPEVIFKCERCGKVCRTQKLLELHVQKCGLLELPGTPVPSVPPTPSSMGSPPPLGEAAAAAPATPTLETLSDLLRYEFAMRAPIELQDLLMATMEKKRAADAAAAAIVSTPAVVAAPNPAPPNAAARHTYRCEICFKAYSQYPSLVKHRKLHLKTPRARTKSTEADDRPYYCDICGKNFKFNRNLKVHMKLHTKANGFYKCDKCSGTFETGELLKTHLLEHPIDVEKIFNCEFCSNTFKSNEDLKRHRRSHTGERPFKCEACPKAFTQLSNLRAHTKIHEKKRPAYGCNICLLELDSLEALNVHLKTHQFQLFELCKDMK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401917;
90% Identity: iTF_00401917;
80% Identity: -