Cpip017355.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culex pipiens
Gene Symbol
-
Assembly
GCA_016801865.2
Location
NC:161928914-161962513[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 3.3e-05 0.001 19.9 1.9 2 23 193 214 192 214 0.97
2 26 3.9 1.2e+02 3.9 3.7 2 23 219 243 218 243 0.87
3 26 8.6e-07 2.6e-05 24.9 0.6 2 23 301 322 301 322 0.98
4 26 0.024 0.73 10.9 0.2 2 23 383 404 382 404 0.97
5 26 0.012 0.37 11.9 2.6 1 23 475 498 475 498 0.95
6 26 8.4 2.6e+02 2.9 0.1 1 21 535 555 535 558 0.85
7 26 0.00023 0.007 17.3 4.0 1 23 573 595 573 595 0.95
8 26 0.0038 0.12 13.4 7.1 1 23 602 624 602 624 0.99
9 26 7.8e-05 0.0024 18.7 1.8 3 23 639 659 637 659 0.96
10 26 4.5e-05 0.0014 19.5 1.4 1 23 665 687 665 687 0.99
11 26 1.2e-05 0.00036 21.3 3.1 2 23 694 715 693 715 0.97
12 26 1.9e-06 5.9e-05 23.8 1.3 1 23 721 743 721 743 0.98
13 26 0.00044 0.013 16.4 0.1 1 23 749 773 749 773 0.93
14 26 0.42 13 7.0 0.2 3 23 1674 1694 1672 1694 0.96
15 26 7.3e-05 0.0023 18.8 2.9 2 23 1701 1722 1700 1722 0.98
16 26 0.09 2.8 9.1 0.3 3 23 1728 1749 1726 1749 0.92
17 26 0.0002 0.0061 17.5 0.3 3 23 1786 1806 1785 1806 0.98
18 26 0.3 9.1 7.5 1.1 3 23 1881 1902 1880 1902 0.97
19 26 0.43 13 7.0 1.2 3 21 1910 1928 1910 1929 0.97
20 26 8e-05 0.0024 18.7 1.2 1 23 1988 2010 1988 2010 0.98
21 26 1.4e-06 4.4e-05 24.2 3.0 1 23 2017 2039 2017 2039 0.98
22 26 1.7e-06 5.3e-05 23.9 0.3 3 23 2057 2077 2056 2077 0.98
23 26 5.7e-05 0.0017 19.2 2.4 1 23 2083 2105 2083 2105 0.99
24 26 7.9e-06 0.00024 21.9 2.2 3 23 2113 2133 2111 2133 0.97
25 26 2.2e-06 6.8e-05 23.6 1.1 1 23 2139 2161 2139 2161 0.99
26 26 0.0069 0.21 12.6 0.0 1 22 2167 2188 2167 2191 0.92

Sequence Information

Coding Sequence
ATGGACCCGTCCGTCGACTTCGATCTGGCCAAACTGTGCCGGTGCTGCCGCAAGCGGGGCTCGGGCCTGCAGTCCATCTTCACCTTCGTCTGCAAATCCGGTGCCGCCACACTGCACGAGATGCTGCTCATTTGCATCCCCCAGTCGCAGCTCCAACCGGACGACGGTCTGCCGGAGCAGCTGTGCTCGCGGTGTATCGCCGCCGTCAGCTCGGCGTACCATTTCCGGAAGCGGTTCGAGGAGAGCGATGGGATTTTGAGGGCGTATGTGAAGGAGAGGGGTCGACAGGTGGAGAGCTTGCTGGGGGGGATGTCTGTGAAGGTGGAACTGGTGGACATTAAGGCGGAGCAGATTATCGTTGAGGCGAATCCGCTGGTTGAGGAGGAGCAGGAGGAAGAACAGGTGGAACCCGTCAAGGTGGAGCTGCAAATGGATTCCGATGATGGAAGTGAATTTGTGGGGGATGATAATGTGGACTTTAGTTCGGAGGAGGAGCAGTACGAGGAGAAGCCCAAAGTTAGTGGTGAGAAAAAAAGAGTCAGGAATCGGAAGAAGCCGGATCCGAGCGAGTACAAGGAATGTCCCACGTGTGGGAAGAAGTTTGATACAAAGTATCACTTGGACAGACACGTGAGGGCGCACAAGAATGACACCCAGTGCGAGCATTGCGAGAAGCGATTCTCGGCCATGGATTATAAGGACTATCGGAAGCACATGCTGACGGATCATCCTGGGATGGACATTCAGCCGCACAGGAAATCGACGGACAAGTCGGAAGGTCGAGACGATGAGGGCAGTGATAATGTGCCAAGTGCCAACGAGCCGGACGAGGATGACGAAGACAAGCCCGCTGGTAAAAAGAAAAGAGCCGGGAAACGGCGAGGTGCGAACGAGTACCGGGAATGTCCAATATGCGGCAAGGGTTTCCCCTCGAAGTATCACCTGGAGAGGCACGTTAAAACGCACAACAACGACACCAGGTGCGAGTTCTGCGACCAACAGTTCTCCGCCACGGCTTACAAAGAGTACTGCGAGCACATGCAGCTGGAACATCCCGGAATGCCGGTTCAACCGCACAAGAAGACAAAACCCATTGATAATTCGCTGGTCGAAGAATTCTtcaaaagtattcagcaaaaggaaatttccTGCAAGCTGTGCGATGCCAAACTTGAGCGGATCGCAGAGTTGCGGAACCACCTACGAACTCACTCCGATCCCAGCACGCTGATCAACGCAGGCATCCCGACAAAGACGTTCCTCTTCGCGGAGGGTTACGTCCCGGACAATTACCTCGACATCTTGGTTCAGCAAATCAATAACTGGGACGTACAACGCTTCTACCAGATCGTCGAACCCACCGGCGAAGAACTCACCTTAAGCGATTCCGACTCCGACCCGGAAGACCTCGTCCAACGAGTCCACACCTGCTTCATCTGCCACCAGAGCTTCCCCCGGCTCAAACTCCTCACCGACCACGCCGCCACCAGCCACAACCCCGAACAACTCCTCACCTGCCAGCACTGCCAGCAGCAAGGCTTCCCAAACAACACCATCCTCGAGCGTCACCAGCGGCAGCAGTGCGCCAATAGCGCCAAAAAGTTCCTCTGCGCCATCTGCAACACCAAGTTCATGTGGCAATCCAGTCTCGATAAACACGCCGCCGCCAACCACGCCAACCCGTCCGCCGATCCGCAGCACGATTCCGGCAAGCGGTTCCTCTGCCCGATGTGCAACAAGGGCTTCACCCAGATGCACCATCTCAAGCGGCACGTCCGCGGCCACGTGCCGTCCGAGAAGAAGTTCGAGTGTCCGGAGTGTCACCGGAAGTTCCACCGCAAGGACAATATGAAGTTTCACATGCGGACGCACCAGCCGAAGCGCGAGGACGAACCGCCCAAGCAGACGCACCTGTGCTCGCTGTGTGGACGGGGGTTTACGTCGAATTACAACTATGTGGTTCATATGCGACGGCACACCGGGGAGAGGCCCTTCAAGTGTGATCAGTGTGATAAGGCTTTCCCGCGTTCGCTGGATTTAACGTATCACAAACGGACGCACACTGGCGATAAACCGAGCGTTTGCAACATATGTGGCAAGGcattctcgcgccatcACCGCCTGGTCCGTCACATGCGCGTCCACACCGGCGCCCGGCCCTACGCTTGCACCTACTGCGACCGTACCTTTACCCAGTCCAACGACCTCACGCTGCACATCCGACGGCACACCGGCGAGAAGCCCTACTCCTGCCCCATCTGTAACGAGCGCTTCATCCAGGGAACGGCCCTGCGCGCCCACCAGCGCTCCGTCGGCCACATCACCGAGGAGACACTGCTTCCGGTGAGCAACTACGGGCGCAGTTTGCTGGAGGGTTGTCGTAGTTTAGCGAATCGGAATTCGTCGGATGCCCCAGCGGAGGCGCAGCTTGCCGTCTTTGAGGTAGATTTCGGCGCGGCTTTTGAGCAAAAAGTCCGGCATGAAGAGGACGCGTTCGAGCGTGCGGCCGCTCTGTCGCAGGGTCCACCCGTTGGCGTCGACCGTGAGCAGTTCGACAAAGTACTCGTGGCACGTGGGAGGGTCCGCCGGGGGACCGTCTTCGCACTGGCCAATCGTGACGGCCATGTGCCTGCGCTCGTGTTCGGTGGCGCCCTGGTTCAGTCTGACTTCGAGTCGCCAAGCGATTTTGTTCGCGTCCAGCAGCGTTTGGGATTGAGTCGTGCGGCTGGTCAGGAAGTCCGGGATCGTGAGGTGGCCCTCGACGAACTTGGGCATCCGTTTGAGGTTGTGATCAGCAGGAATCTGCTTCAGTCTTTTACCCAACACGAGGGTGCTCCGCTCGGCGTCCGGATCCAAGGGGACTATGGCCACGCGCAGCTTGAGAGTGCCGTCCGCGGCAAAGTAGCCATCGTCGCGCAGCTGGGACACGGCAGCGAGCGTGCTGCAGTAGACCGTCCGGAGGCGACTCACTTCCATCGAATCGCTGCGCTGGAAGCTCTTGAGTGGAGATTCGTGGATGAAGCGCACCAACAGCTGGAAACGTCCCATCACGCCACGGCACTGGCTCGTGTCGACGTCCAAAATCAACCAGTCCATGTCCTTGCGGAGGCGCAACTGCCACGGAACACCGTACTGGTCACGGATGGTGGTCGCGCTCGTGGCATCTTCCACGATTCCCACACTGATGATCGACGGAACCTACTAGGAGTGGTCGTACTGCGGCAGCGGCACCTTCACCTTCGCCGGCTCCACGTCCTGCGCCAGCCGCGCCACATCGAACAGCTTCATCAGCTGATCCTGCTGCTTGGTCTGCAGGCTCTTCAGCAGCTGCCCACTTTCGTTCCGGAGCGCCCGCTCGACCACCTTCTGCATCTGCTTCTTCGGGTCGAGCGCGGCCATAATTTCCGCAAGCTCCCCCGCCAGCACCGCATTCTGCTCCGGCGGTTTTTCCTTCGCTTCCGGCTGGTCCTTGTCCTTGGGCAGCACGTCAAAGTGGTGGCACAGCACCCACAGGCTGTGCTCGATCTCCTCCAGCTTCCGGGCGTGCTGCTCGTTGGTGATGTGGTCCGGCAGGACGGGGCGCTTGTAGCGTCGGTCGGCCGTCGTGGTGGCCACGTCGAAAAAGACGATCGCCGGACACGGCTGGAAGCTCTTGGATGCGGTGGCCATTTCTTTCTTCGCAGCGGGGGAGATTCTTTGCTGGCGGGAAGACCGAAGCCCATATCGTCGTCCTCGGACTCGGACTCTTCCTTCTTCTCCTCCTTGGCGGCGGCAGCCGGAGCGgccgaagcagcagcagcagccggggCAGCGACCGCGGCGAACTTGCTCGGGTCCTTGATGAACTCCTTGACCGTTTCGGCCTCCTTGAACTCGACCTCGGTGACGGCGGCGATGGCCAGCAGGTTGCGGAAACCGTTGGCAATGCTGTGCGGCACGGAAGCCAGCGTCGGAATCTCCGGCGAGAAGATCGAACCAGAGTCGTACACCTGCTCAATCTGCAGACCGTACGAGAACGGCGAGATGTTCAACATGTTGAGCAGCGTGGCCTCGGAAGCTCCGACCTTGTCACCGGGCTTCAGAATGGGCACATCGTTGATGATTTCAATCGTACCCTTGGAAATCTTGGTCGGGATGGACAGCGCCTGGAAGAAGGAGGTCTTCTCGGGGCCGAGACCGGTGTTCTGGGCCGGGATGATGACCTCCAGCGGAGCGATGGCACCAGCACGAGCCGGGGCACGCACCTTGCTCTCCATCAGCTTGTCGCGGATGTCGGCCAGATCGCCCTTGGTGAACACGAAGCCGACATTGCCGCGGATGTGCGGCAGCAGCTTCTCCAGGACGATGGCCGAGCCACGGAGCGAGATACGGATGGTCTGCATCTGGCGGGAACCGACATTGTCGGCGCCCACGATGAAGCACTTGGGGTACTCATCGAGCAGTTGCTCACCTTCGGAGCGCTTCCAAACAATGGAGGTAATCGACATGAACCTCGAGTACGACCTGGCCCGCATCTGCCGGTGCTGCCGTCGCGACTCCCCGGATCTGCAACCCATCTTCCTGGACGGTGCCGCCGTCGCAGACGGCACCACGCTGTACGAAATGCTCGCCAGCTGCACCCAGAGCCAGCCGAACTTCAACGACGGCTTGCCGTCGCAGCTGTGCGGGGATTGCGTCTCGGAGGTGACCACGGCGTACGGGTTCCGCAAGCGGTACGAGCAGAGTGAGTTGCTGCTGCGGGAGTATCTGTCGCGGAGGAAGGTGGAGCCTGCGGCCTGCGGGGTGAAGGTAGAGGAGCTGTTTGACGTCAAGACGGAGCTGATCGTGGTGGAGACTGTTGGGGAGGAGGAGGATGAGTTGATGACGGTGGAGTTTGTGGAGGAGAGTGGGGAGGATGAGGATCAAGATTATGAGGTGGGAAGTTTGGACGAGATGATTGAGGAGTTGGAGGAGTTGAAGCCGCAGGCGAGGGGGCGGAAGGCGAATGGGTATTCGAAGATTAAGGGGGGAGGATTTGGGTGCGATTCTTGCGAGCGGGTGTTTGCGGATCGTCGGGGGATTACGAACCACGTGAAGCAGCATGAAAGGAAGGAGGTGAAGCAGTGTCCGCTGTGCAGCCGGGAGTTTACCTCGTCGTATCACTTGAATAGGCACGTGAAGATGCACGAAAACGACACGGATTGCGGGGTTTGCGGGAAGAAGTTTGGGCTTTATCACGACTACAAGGACCACATGGCGGCGGAACATCCGGGGGTGGCGTTGGTGGAGCCGAAGAAGACGGAGCGGTCGGAGCGTGAGCTGGCTCTCACGTTGACGGCGGAGCTGTTGGAGGATCCGGGCAGGATGGAAGCGATTTGTCGGATTTGTGACGCCACGTTTGAGCGGATAGCGCAGCTGAGGAGGCATCTGCGGACGCACGAGGATGTGAAGTCGTTTGAGAACgtcaacatcgccaacaagccGTACCTGTTTGAGGAAGGTTACGTGCTGGAGAACTACCTCGAGTACCTGGTGCAGCAGGTTTGCAAGGGGAATCTGTTGCGATTCTACCAGATTGTCGAGCCTGACGGTGAGGAGTTGGAACTGAGCGATTCCGACACGGATGGTGAAGATGAGGAAGTGGTTCGACGCGAGCATGGTTGTGGCCTCTGTCAGCAGAGCTTCCCGCGGATTAAACTGCTCCGCGAGCACGCTAAAAGTTGCCATCGTCCGGAAGAATTGATCGGTTGCAAGCACTGCGCCCGAGGCTTCCCCAACACGACCCTCTTCATGCGGCACCTGCGCCAGCAGTGCGAAAACACCGTCAAGAAGTTCCACTGCACCTTTTGCAACGAAAAGTTCATGTGGCAAACCTCGCTCAACAAGCACGCCCAGCACCACCACAAACCCACGAAACCGCTCTGGGAGCGACCCGGCGACGAGTCCGGAACCTCAGCCGCGAACGAAGAATCCGCGAAAAAGTTCGTCTGCCAAGTCTGCTCCAAAGGCTTCCAGCGGCTGGAACACCTCGAGCGCCACATCAAGATCCACATCCCGTCGGAGAAAAAGTTCGAATGTCCCGTCTGCCACAAAAAGTTCAACCGCAAGGACAACCTCCGCTCGCACCTCAAAATCCACCAAAAAGACCCCGACGCGGACGCCGACCCCGCCAACAAGCAGAACCAACTGTGCGTCTACTGCGGCCGCGGCTTCTCCAACTCCTCCAACCTCATCGTCCACATGCGACGCCACACCGGCGAACGCCCCTACCGCTGCGACATCTGCGACAAGGGCTTCCCCCGCTCCTCGGACCTCCAGTGCCACCGCCGAACGCACACCGGCGAAAAGCCCTGTCTCTGCACCATCTGCGGCAAGGGCTTCTCCCGCTCCAACAAACTGGTCCGCCACATGCGCATCCACACCGGCGCCCGGCCCTACTCCTGCTCGTACTGCGACCGCGCCTTCACCCAGTCCAACGACCTCACCCTGCACATCCGGCGCCACACCGGCGAAAAACCCTACGTCTGCGGCGTCTGCAACGAGCGCTTCATCCAGGGCACCGCCCTCAAGGCCCACCAGCGCGCCACCGGCCACAACGACGACGGCGCCACCCAGCCGGAACGCTTCGCCGCAATCAGCGTCAACAACCCGCACCGGATGGGCGTGAACGGGCCGAAGGCTCTGCGACAAAGCGCCACCGTCAAAGCGGTCAAGTCGCGCAAGAAGAAGGCGGCCGCCGCCGTAGAACCGATGACCGTCGTCGAGGAGGTGGCTGCGCCCCCACCGCAACCGTACGTCCCGACCGTGCCGTCGTACGTCATGCAGAACTACGACCTGACGGCCGGCGGGTTGTTTGCGCAGAGTTTTACCCAGCAGTAg
Protein Sequence
MDPSVDFDLAKLCRCCRKRGSGLQSIFTFVCKSGAATLHEMLLICIPQSQLQPDDGLPEQLCSRCIAAVSSAYHFRKRFEESDGILRAYVKERGRQVESLLGGMSVKVELVDIKAEQIIVEANPLVEEEQEEEQVEPVKVELQMDSDDGSEFVGDDNVDFSSEEEQYEEKPKVSGEKKRVRNRKKPDPSEYKECPTCGKKFDTKYHLDRHVRAHKNDTQCEHCEKRFSAMDYKDYRKHMLTDHPGMDIQPHRKSTDKSEGRDDEGSDNVPSANEPDEDDEDKPAGKKKRAGKRRGANEYRECPICGKGFPSKYHLERHVKTHNNDTRCEFCDQQFSATAYKEYCEHMQLEHPGMPVQPHKKTKPIDNSLVEEFFKSIQQKEISCKLCDAKLERIAELRNHLRTHSDPSTLINAGIPTKTFLFAEGYVPDNYLDILVQQINNWDVQRFYQIVEPTGEELTLSDSDSDPEDLVQRVHTCFICHQSFPRLKLLTDHAATSHNPEQLLTCQHCQQQGFPNNTILERHQRQQCANSAKKFLCAICNTKFMWQSSLDKHAAANHANPSADPQHDSGKRFLCPMCNKGFTQMHHLKRHVRGHVPSEKKFECPECHRKFHRKDNMKFHMRTHQPKREDEPPKQTHLCSLCGRGFTSNYNYVVHMRRHTGERPFKCDQCDKAFPRSLDLTYHKRTHTGDKPSVCNICGKAFSRHHRLVRHMRVHTGARPYACTYCDRTFTQSNDLTLHIRRHTGEKPYSCPICNERFIQGTALRAHQRSVGHITEETLLPVSNYGRSLLEGCRSLANRNSSDAPAEAQLAVFEVDFGAAFEQKVRHEEDAFERAAALSQGPPVGVDREQFDKVLVARGRVRRGTVFALANRDGHVPALVFGGALVQSDFESPSDFVRVQQRLGLSRAAGQEVRDREVALDELGHPFEVVISRNLLQSFTQHEGAPLGVRIQGDYGHAQLESAVRGKVAIVAQLGHGSERAAVDRPEATHFHRIAALEALEWRFVDEAHQQLETSHHATALARVDVQNQPVHVLAEAQLPRNTVLVTDGGRARGIFHDSHTDDRRNLLGVVVLRQRHLHLRRLHVLRQPRHIEQLHQLILLLGLQALQQLPTFVPERPLDHLLHLLLRVERGHNFRKLPRQHRILLRRFFLRFRLVLVLGQHVKVVAQHPQAVLDLLQLPGVLLVGDVVRQDGALVASVGRRGGHVEKDDRRTRLEALGCGGHFFLRSGGDSLLAGRPKPISSSSDSDSSFFSSLAAAAGAAEAAAAAGAATAANLLGSLMNSLTVSASLNSTSVTAAMASRLRKPLAMLCGTEASVGISGEKIEPESYTCSICRPYENGEMFNMLSSVASEAPTLSPGFRMGTSLMISIVPLEILVGMDSAWKKEVFSGPRPVFWAGMMTSSGAMAPARAGARTLLSISLSRMSARSPLVNTKPTLPRMCGSSFSRTMAEPRSEIRMVCIWREPTLSAPTMKHLGYSSSSCSPSERFQTMEVIDMNLEYDLARICRCCRRDSPDLQPIFLDGAAVADGTTLYEMLASCTQSQPNFNDGLPSQLCGDCVSEVTTAYGFRKRYEQSELLLREYLSRRKVEPAACGVKVEELFDVKTELIVVETVGEEEDELMTVEFVEESGEDEDQDYEVGSLDEMIEELEELKPQARGRKANGYSKIKGGGFGCDSCERVFADRRGITNHVKQHERKEVKQCPLCSREFTSSYHLNRHVKMHENDTDCGVCGKKFGLYHDYKDHMAAEHPGVALVEPKKTERSERELALTLTAELLEDPGRMEAICRICDATFERIAQLRRHLRTHEDVKSFENVNIANKPYLFEEGYVLENYLEYLVQQVCKGNLLRFYQIVEPDGEELELSDSDTDGEDEEVVRREHGCGLCQQSFPRIKLLREHAKSCHRPEELIGCKHCARGFPNTTLFMRHLRQQCENTVKKFHCTFCNEKFMWQTSLNKHAQHHHKPTKPLWERPGDESGTSAANEESAKKFVCQVCSKGFQRLEHLERHIKIHIPSEKKFECPVCHKKFNRKDNLRSHLKIHQKDPDADADPANKQNQLCVYCGRGFSNSSNLIVHMRRHTGERPYRCDICDKGFPRSSDLQCHRRTHTGEKPCLCTICGKGFSRSNKLVRHMRIHTGARPYSCSYCDRAFTQSNDLTLHIRRHTGEKPYVCGVCNERFIQGTALKAHQRATGHNDDGATQPERFAAISVNNPHRMGVNGPKALRQSATVKAVKSRKKKAAAAVEPMTVVEEVAAPPPQPYVPTVPSYVMQNYDLTAGGLFAQSFTQQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00401903;
90% Identity
iTF_00401903;
80% Identity
-